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Thermotogae
Classification of phyla is from NCBI page
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132 projects found  

3 accessions found for Novosphingobium aromaticivorans DSM 12444  

Data for CP000248  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000248.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000248_1992 CDS_2137295-2134947 86.9 2.2e-24 1
CP000248_2263 CDS_2415703-2416887 86.1 3.8e-24 1
CP000248_1655 CDS_1743718-1745310 75.7 3.4e-21 1
CP000248_0386 CDS_426051-424543 61.9 2.7e-17 1
CP000248_2892 CDS_3124042-3122465 59.7 1.2e-16 1
CP000248_1623 CDS_1709143-1707602 55.6 1.6e-15 1
CP000248_1920 CDS_2041595-2043823 54.3 3.8e-15 1
CP000248_1918 CDS_2038957-2040078 53.7 5.7e-15 1
CP000248_2614 CDS_2846748-2843398 49.9 6.7e-14 1
CP000248_1765 CDS_1871233-1872684 49.4 9.3e-14 1
CP000248_1503 CDS_1555621-1554185 44.5 2.4e-12 1
CP000248_1441 CDS_1489693-1492128 42.2 1e-11 1
CP000248_0036 CDS_37528-39198 41.9 1.3e-11 1
CP000248_1568 CDS_1632386-1633933 39.8 4.9e-11 1
CP000248_1345 CDS_1397264-1395459 37.2 2.8e-10 1
CP000248_1591 CDS_1663284-1664690 33.0 4.1e-09 1
CP000248_0441 CDS_481428-482825 29.3 4.8e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000248_1992 1/1 559 627 .. 1 87 [] 86.9 2.2e-24
CP000248_2263 1/1 165 233 .. 1 87 [] 86.1 3.8e-24
CP000248_1655 1/1 88 152 .. 1 87 [] 75.7 3.4e-21
CP000248_0386 1/1 273 341 .. 1 87 [] 61.9 2.7e-17
CP000248_2892 1/1 297 362 .. 1 87 [] 59.7 1.2e-16
CP000248_1623 1/1 282 349 .. 1 87 [] 55.6 1.6e-15
CP000248_1920 1/1 506 577 .. 1 87 [] 54.3 3.8e-15
CP000248_1918 1/1 148 204 .. 9 87 .] 53.7 5.7e-15
CP000248_2614 1/1 757 821 .. 1 87 [] 49.9 6.7e-14
CP000248_1765 1/1 258 322 .. 1 87 [] 49.4 9.3e-14
CP000248_1503 1/1 264 323 .. 1 87 [] 44.5 2.4e-12
CP000248_1441 1/1 430 496 .. 1 87 [] 42.2 1e-11
CP000248_0036 1/1 171 239 .. 1 87 [] 41.9 1.3e-11
CP000248_1568 1/1 284 354 .. 1 87 [] 39.8 4.9e-11
CP000248_1345 1/1 353 421 .. 1 87 [] 37.2 2.8e-10
CP000248_1591 1/1 238 303 .. 1 87 [] 33.0 4.1e-09
CP000248_0441 1/1 255 313 .. 1 87 [] 29.3 4.8e-08

Alignments of top-scoring domains:
CP000248_1992: domain 1 of 1, from 559 to 627: score 86.9, E = 2.2e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f+an+s E+RTPLt+I g+aelL+ ++ ++l+e+q
CP000248_1 559 VKTRFIANMSYEFRTPLTSIGGFAELLQS------GIAGDLTEQQ-- 597

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+e il ++erl ++i+++Ldls+ eag
CP000248_1 598 ----------NEYVEAILTSVERLGEQIENVLDLSQSEAG 627

CP000248_2263: domain 1 of 1, from 165 to 233: score 86.1, E = 3.8e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+an+sHELRTPL++I+gy+e+L + d++ +e ++
CP000248_2 165 AHTDFVANASHELRTPLASIIGYIETLAD-------PDAKVDEATA- 203

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ t+lrea+rl++L++dl+ lsriea+
CP000248_2 204 ----------ARFHATVLREARRLQSLVEDLMSLSRIEAE 233

CP000248_1655: domain 1 of 1, from 88 to 152: score 75.7, E = 3.4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+ la++sHE+R PL+aI gya+l ++ e + +
CP000248_1 88 AKSRYLASVSHEIRSPLNAIYGYAQLVER----------EGTVDP-- 122

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ ++i+r+ae+l +L++ lLd++ ie+g
CP000248_1 123 ----------RDAARVIRRSAEHLTNLVEGLLDIASIEQG 152

CP000248_0386: domain 1 of 1, from 273 to 341: score 61.9, E = 2.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks +l+++sH+LRTPLtaI++ a+ L e++ + + e+
CP000248_0 273 LKSALLSSVSHDLRTPLTAISASASSLIEFG-------SRFDRETS- 311

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l+ i +e +rl+r +lL+lsr++ag
CP000248_0 312 ----------KALLQGIVDECDRLNRFTANLLELSRLQAG 341

CP000248_2892: domain 1 of 1, from 297 to 362: score 59.7, E = 1.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+a+++HEL++PL++++ ++e++++ e ++
CP000248_2 297 AVEMFAADVAHELKNPLASLSSALETMER---------VEDPALR-- 332

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ ++ ++++r++rLi ++ d sri+a+
CP000248_2 333 ----------RQLAGIAAHDVQRIDRLITEIADASRIDAE 362

CP000248_1623: domain 1 of 1, from 282 to 349: score 55.6, E = 1.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++fla++sHELRTPL+ +r ae+ l+ ++++ +++
CP000248_1 282 LRRQFLADASHELRTPLSIMRSEAEITLR--------KADADMDEL- 319

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l+++ r + + ++i+d+L+ +r+e++
CP000248_1 320 ----------RTGLDRVVRLSALMAEMIEDMLQVARAEEP 349

CP000248_1920: domain 1 of 1, from 506 to 577: score 54.3, E = 3.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a s+ ++ ++HE+++PLt I++++e L++++ g++ +++++
CP000248_1 506 AWSDVARRIAHEIKNPLTPIQLATERLKRRY-----GRQIENDPEL- 546

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++e+++ti+r++ l+++++++ ++r+ +
CP000248_1 547 ---------FEELTSTIIRQVGDLRKMVDEFSSFARLPKP 577

CP000248_1918: domain 1 of 1, from 148 to 204: score 53.7, E = 5.7e-15
*->lsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrlpeLRledp
l+HE+++PL++I+g+a+lL + +lse +
CP000248_1 148 LAHEIKNPLAGIKGAAQLLDR----------KLSESD---------- 174

eyreyletilreaerllrLindlLdlsrieag<-*
r ++ i e++r+ +Li+++ lsr a+
CP000248_1 175 --RAMTGLITAEVDRIAKLIDQMQSLSRRSAE 204

CP000248_2614: domain 1 of 1, from 757 to 821: score 49.9, E = 6.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++fla++sH+L +PL+a r++a++L + +l
CP000248_2 757 EKTRFLAAASHDLLQPLHAARLFASALDR----------NLEGNA-- 791

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++r++ ++L++ lLd+s+++ag
CP000248_2 792 ----------KVLAARVDRSIVAAEALLRALLDISKLDAG 821

CP000248_1765: domain 1 of 1, from 258 to 322: score 49.4, E = 9.3e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++la ++HELRTPL+++rg +e+L++ + + + +
CP000248_1 258 ARRRWLAEIAHELRTPLAVLRGEIEALRD---------GIRQPGRAE 295

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++l ea +l rL++dl ls e +
CP000248_1 296 -------------IDSLLAEAGSLGRLVDDLHFLSVSELE 322

CP000248_1503: domain 1 of 1, from 264 to 323: score 44.5, E = 2.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+l+H++RTPLt I g + L +
CP000248_1 264 LRRTLLASLAHDFRTPLTIITGRLAELASG----------------- 293

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +a+r++r+ ndl +rieag
CP000248_1 294 ----------NPAATDALAAAQRMDRMMNDLIGAARIEAG 323

CP000248_1441: domain 1 of 1, from 430 to 496: score 42.2, E = 1e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ LtaI+gy++l+l+ +++ ++ +
CP000248_1 430 AVGQLAGGVAHDFNNVLTAIIGYCDLMLM--------RHTPGDSD-- 466

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ++ ++r +L ++lL +sr ++
CP000248_1 467 ----------YDDIQQVKANSNRAASLTRQLLAFSRQQTL 496

CP000248_0036: domain 1 of 1, from 171 to 239: score 41.9, E = 1.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I g+ e++ ++l+ + ++++
CP000248_0 171 AVGQLTGGLAHDFNNLLAGITGAFEMIARRLE------QGRTADV-- 209

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl l +a+r +L +lL +sr ++
CP000248_0 210 ----------ERYLAAGLGAAHRAAALTHRLLAFSRRQTL 239

CP000248_1568: domain 1 of 1, from 284 to 354: score 39.8, E = 4.9e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++e++++l+HE+++PL+aI y+ + l+ +++ + + +
CP000248_1 284 ALGEMASALAHEINQPLSAIANYLRGSAT-----LLARPDPPLDRV- 324

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++e++ +ea r ++i++l+d+ ++
CP000248_1 325 ----------ADAVERAAKEALRAGDIIRRLRDFVGRGET 354

CP000248_1345: domain 1 of 1, from 353 to 421: score 37.2, E = 2.8e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + l+ l HELRTP++aI+g+ae+++ +++ +++ q
CP000248_1 353 SEADRLRQLLHELRTPINAIQGFAEVIQQQVF-------GATPHQ-- 390

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr + +i +a +l+ +++ l ++e+
CP000248_1 391 ---------YRAMAASIAADAAVMLAGFEEVERLVKLESR 421

CP000248_1591: domain 1 of 1, from 238 to 303: score 33.0, E = 4.1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + l+H+L+ PLt ++ +++ + + + ++e
CP000248_1 238 ELKIATDVLAHDLKSPLTRLLSALDRASA---------RAEDAEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++e ++ ea+r l++i+ L +s++eag
CP000248_1 274 ----------LAAVEQAEAEARRVLSIIDTALGISKAEAG 303

CP000248_0441: domain 1 of 1, from 255 to 313: score 29.3, E = 4.8e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+ +l ++ H+L+TPL+a+r +e+ + + +
CP000248_0 255 EKDVMLGAIGHDLKTPLAALRVRIEAVDD-------------DTE-- 286

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +e ++r ++d+L l+r + +
CP000248_0 287 -------------RARMAATIEDINRSLDDILSLARVGRP 313


Histogram of all scores:
score obs exp (one = represents 12 sequences)
----- --- ---
-14 3 0|=
-13 31 2|*==
-12 121 75|======*====
-11 285 394|======================== *
-10 518 730|============================================ *
-9 688 754|==========================================================*
-8 599 565|===============================================*==
-7 445 356|=============================*========
-6 281 204|================*=======
-5 146 112|=========*===
-4 84 60|====*==
-3 44 31|==*=
-2 25 16|=*=
-1 13 8|*=
0 11 4|*
1 2 2|*
2 3 1|*
3 1 0|=
> 4 24 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 207.5826
P(chi-square) = 1.981e-38

Total sequences searched: 3324

Whole sequence top hits:
tophits_s report:
Total hits: 17
Satisfying E cutoff: 17
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 17
Satisfying E cutoff: 17
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: