Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
132 projects found  

2 accessions found for Jannaschia sp. CCS1  

Data for CP000264  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000264.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000264_0265 CDS_272732-274882 97.9 2.2e-27 1
CP000264_2288 CDS_2294101-2295141 85.9 5.4e-24 1
CP000264_0537 CDS_527405-529129 67.4 9.6e-19 1
CP000264_2693 CDS_2705751-2703070 66.1 2.3e-18 1
CP000264_1833 CDS_1818999-1820306 54.7 3.8e-15 1
CP000264_2013 CDS_2020089-2018857 50.2 7.1e-14 1
CP000264_2237 CDS_2241755-2242822 50.2 7.2e-14 1
CP000264_2239 CDS_2244354-2246624 47.4 4.6e-13 1
CP000264_1984 CDS_1980629-1982887 46.3 9.3e-13 1
CP000264_2542 CDS_2547963-2546197 45.5 1.6e-12 1
CP000264_4060 CDS_4164349-4165773 38.8 1.2e-10 1
CP000264_1731 CDS_1724847-1722982 35.8 8.5e-10 1
CP000264_1796 CDS_1785771-1784416 34.8 1.7e-09 1
CP000264_0646 CDS_616749-618203 29.1 6.8e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000264_0265 1/1 218 283 .. 1 87 [] 97.9 2.2e-27
CP000264_2288 1/1 115 182 .. 1 87 [] 85.9 5.4e-24
CP000264_0537 1/1 345 410 .. 1 87 [] 67.4 9.6e-19
CP000264_2693 1/1 667 734 .. 1 87 [] 66.1 2.3e-18
CP000264_1833 1/1 229 287 .. 1 87 [] 54.7 3.8e-15
CP000264_2013 1/1 211 272 .. 1 87 [] 50.2 7.1e-14
CP000264_2237 1/1 128 192 .. 1 87 [] 50.2 7.2e-14
CP000264_2239 1/1 516 588 .. 1 87 [] 47.4 4.6e-13
CP000264_1984 1/1 376 442 .. 1 87 [] 46.3 9.3e-13
CP000264_2542 1/1 363 431 .. 1 87 [] 45.5 1.6e-12
CP000264_4060 1/1 217 271 .. 1 75 [. 38.8 1.2e-10
CP000264_1731 1/1 390 458 .. 1 87 [] 35.8 8.5e-10
CP000264_1796 1/1 212 277 .. 1 87 [] 34.8 1.7e-09
CP000264_0646 1/1 265 329 .. 1 87 [] 29.1 6.8e-08

Alignments of top-scoring domains:
CP000264_0265: domain 1 of 1, from 218 to 283: score 97.9, E = 2.2e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks flan+sHE+RTP++++ +aelL++ t+l+eeq
CP000264_0 218 AKSHFLANMSHEIRTPMNGVVSMAELLRD---------TALDEEQ-- 253

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ y +ti++++e ll +ind+Ld+s+ieag
CP000264_0 254 ----------QMYADTIRSSGEALLVIINDILDFSKIEAG 283

CP000264_2288: domain 1 of 1, from 115 to 182: score 85.9, E = 5.4e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHELRTPLt+++g++e+L+ ++++++ ++
CP000264_2 115 MRRDFVANVSHELRTPLTSVMGFIETLRG---------PARNDPAAQ 152

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l +++ ea r++rLi+dlL ls+ ea
CP000264_2 153 ----------DRFLGIMEAEAGRMNRLISDLLSLSKVEAA 182

CP000264_0537: domain 1 of 1, from 345 to 410: score 67.4, E = 9.6e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHE+++PL+++r ++ +L+ +++++qr
CP000264_0 345 SNEQFAADVSHEIKNPLASLRSAVGTLEF----------AKTDDQR- 380

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++i+++++rl+rL++d+ sr++++
CP000264_0 381 ----------KRLIDVIEHDVHRLDRLVSDISNASRLDSE 410

CP000264_2693: domain 1 of 1, from 667 to 734: score 66.1, E = 2.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+ fl+ +sHELRTP+t+Ir+++e+L +++ ++ r
CP000264_2 667 QKDAFLSQISHELRTPMTSIRAFSEILMQ--------SDPVDDAAR- 704

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +++++e+ rl rL++dlLdls +e+g
CP000264_2 705 ----------LRFSRIMHDESLRLTRLLDDLLDLSVLENG 734

CP000264_1833: domain 1 of 1, from 229 to 287: score 54.7, E = 3.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +l+++sH+LRTPLt +r+++ ++++
CP000264_1 229 QRTLMLSGVSHDLRTPLTRMRLALGMMED------------------ 257

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++e ++ L+ +Ld+ r +a
CP000264_1 258 ----------GPDRDALVQDVEEMEVLVATFLDFVRGDAL 287

CP000264_2013: domain 1 of 1, from 211 to 272: score 50.2, E = 7.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + +lan+sHELRTPL+ Ir+ +e+ +e + +
CP000264_2 211 AHRVLLANASHELRTPLSRIRLGLEMFRE----------TGEAHR-- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l ++ ++ +l++Li+++L+lsr++a
CP000264_2 246 -------------LAHVETDIGQLDSLIDEILTLSRLDAA 272

CP000264_2237: domain 1 of 1, from 128 to 192: score 50.2, E = 7.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++ +l+HE+++PL++I g+a+l+ + ++++e+
CP000264_2 128 SAIGMAEMLAHEIKNPLAGITGAAQLISM----------NANAED-- 162

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re+++ i e++r l+L++++ d+ + +
CP000264_2 163 ----------RELTDLIVAETRRVLKLLEQVEDFGNVRPP 192

CP000264_2239: domain 1 of 1, from 516 to 588: score 47.4, E = 4.6e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++ ++ ++HE+++PLt I++ ae +++++ + l +e++
CP000264_2 516 AWGDVARRIAHEIKNPLTPIQLSAERIKRKF------SRMLEDEDKV 556

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++e+i r+++ l+r+++++ ++r+ ++
CP000264_2 557 SL--------EQMTEVIVRQTNDLRRIVDEFSKFARMPEP 588

CP000264_1984: domain 1 of 1, from 376 to 442: score 46.3, E = 9.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e++ +++H++++ LtaI g+++lLl ++++++++
CP000264_1 376 AIGELAGGVAHDFNNLLTAITGHCDLLLL--------RHDQGDQD-- 412

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l i + a+r +L+ +lL +sr ++
CP000264_1 413 ----------YADLVQINQNANRAASLVGQLLAFSRKQTL 442

CP000264_2542: domain 1 of 1, from 363 to 431: score 45.5, E = 1.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++e+ a++sHEL++PL+a+++y+ ++ l +++ee
CP000264_2 363 ALGEMSAAVSHELNQPLAAMKTYLAGARLLLQ------RKRTEEA-- 401

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++i++ +er+ ++ ++l ++r +
CP000264_2 402 ----------ASSFQRIDDLIERMGAITRQLKSYARKGGD 431

CP000264_4060: domain 1 of 1, from 217 to 271: score 38.8, E = 1.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +a+++HEL TPL++I+++a Ll+ +ls++ +l
CP000264_4 217 DLGGVIAAAAHELGTPLATIKLTATELLD----------DLSDQPTL 253

peLRledpeyreyletilreaerllrLi<-*
+e ++ i+++a+r+ +++
CP000264_4 254 ----------AEDVSLIRDQADRCGDIL 271

CP000264_1731: domain 1 of 1, from 390 to 458: score 35.8, E = 8.5e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++ a+lsHE+++PL+a++ yae + ++ld + +e
CP000264_1 390 ALGQMSAALSHEFNQPLAAVKSYAENAGTFLD------RGRMDEA-- 428

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +++i a+r+ ++ l+ ++r
CP000264_1 429 ----------RGNIQRISGLADRMAAISKHLRNFARRPGD 458

CP000264_1796: domain 1 of 1, from 212 to 277: score 34.8, E = 1.7e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +++ +++H++++ Lta++g +el e + + e
CP000264_1 212 AIGRLSGGIAHDFNNILTALQGSLELYYE---------VPEGQER-- 247

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++++ r +L+ +lL ++r
CP000264_1 248 ----------DALVDEAREAGIRATALVAQLLSFARRAPL 277

CP000264_0646: domain 1 of 1, from 265 to 329: score 29.1, E = 6.8e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e +a +sH+LR+ L++ + a+ L++ +++
CP000264_0 265 QLGEAVAKISHDLRNMLSVATLVADRLET----------VQDPTV-- 299

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++++++ r +L + L + r+e++
CP000264_0 300 ----------KRIAPKLINSLSRAINLTEATLAFGRAEEP 329


Histogram of all scores:
score obs exp (one = represents 16 sequences)
----- --- ---
-14 3 0|=
-13 47 3|*==
-12 179 96|=====*======
-11 430 499|=========================== *
-10 737 926|=============================================== *
-9 887 956|======================================================== *
-8 724 716|============================================*=
-7 497 451|============================*===
-6 326 259|================*====
-5 158 142|========*=
-4 79 76|====*
-3 49 40|==*=
-2 30 21|=*
-1 23 11|*=
0 13 5|*
1 5 3|*
2 5 1|*
3 1 0|=
> 4 19 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 175.4632
P(chi-square) = 3.634e-31

Total sequences searched: 4212

Whole sequence top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: