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Thermotogae
Classification of phyla is from NCBI page
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106 projects found  

2 accessions found for Mycobacterium ulcerans Agy99  

Data for CP000325  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000325.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000325_3788 CDS_5124218-5125720 88.9 7.5e-25 1
CP000325_2139 CDS_2883785-2882106 75.4 5.1e-21 1
CP000325_0388 CDS_477216-478661 72.2 4.1e-20 1
CP000325_3733 CDS_5058614-5059834 69.9 1.9e-19 1
CP000325_3852 CDS_5204730-5203195 62.0 3.3e-17 1
CP000325_0208 CDS_256527-257867 53.4 8.8e-15 1
CP000325_1243 CDS_1624498-1626018 51.1 3.8e-14 1
CP000325_2172 CDS_2928219-2926597 41.3 2.4e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000325_3788 1/1 258 325 .. 1 87 [] 88.9 7.5e-25
CP000325_2139 1/1 295 362 .. 1 87 [] 75.4 5.1e-21
CP000325_0388 1/1 249 313 .. 1 87 [] 72.2 4.1e-20
CP000325_3733 1/1 154 220 .. 1 87 [] 69.9 1.9e-19
CP000325_3852 1/1 239 311 .. 1 87 [] 62.0 3.3e-17
CP000325_0208 1/1 230 296 .. 1 87 [] 53.4 8.8e-15
CP000325_1243 1/1 276 348 .. 1 87 [] 51.1 3.8e-14
CP000325_2172 1/1 296 364 .. 1 87 [] 41.3 2.4e-11

Alignments of top-scoring domains:
CP000325_3788: domain 1 of 1, from 258 to 325: score 88.9, E = 7.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPL+aI+gyael + ++ ++l++ +
CP000325_3 258 RMRQFITDASHELRTPLAAIQGYAELTRQDS-------SDLPPTT-- 295

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +i++ea+r+ +L+++lL lsr+++g
CP000325_3 296 ----------EYALARIESEARRMASLVDELLLLSRLGEG 325

CP000325_2139: domain 1 of 1, from 295 to 362: score 75.4, E = 5.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++++l++
CP000325_2 295 LQRRFTSDVSHELRTPLTTVRMAADLIYD-------HSADLDPTL-- 332

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e + +e++r ++L+ndlL++sr +ag
CP000325_2 333 ----------RRSTELMVNELDRFESLLNDLLEISRHDAG 362

CP000325_0388: domain 1 of 1, from 249 to 313: score 72.2, E = 4.1e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ + ++
CP000325_0 249 RMRRFITDASHELRTPLTTIRGFAELYRQGA-----------ARDV- 283

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l++i++ea r+ L++dlL+l+r++ +
CP000325_0 284 ----------AMLLSRIESEASRMGLLVDDLLTLARLDVQ 313

CP000325_3733: domain 1 of 1, from 154 to 220: score 69.9, E = 1.9e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a+ ++ae+Ll+ ++ +++++
CP000325_3 154 TRRDFVANVSHELKTPVGAMALLAEALLA---------SADDSDTV- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ e++l ea+rl +++ +l +lsr++
CP000325_3 191 ----------RRFAEKVLIEANRLGDMVAELIELSRLQGA 220

CP000325_3852: domain 1 of 1, from 239 to 311: score 62.0, E = 3.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++++++ HELRTPLt++r+++elL + ++ +g + l+e+++
CP000325_3 239 RQARLVSDAGHELRTPLTSLRTNVELLMASME---PGAPRLPEQEM- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e + ++e l+ L+ dl dl+r +ag
CP000325_3 282 ----------VGLREDVVAQIEELSTLVGDLVDLTRGDAG 311

CP000325_0208: domain 1 of 1, from 230 to 296: score 53.4, E = 8.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a sHELRTPLta+r+++e+L + +l+++qr
CP000325_0 230 SARDFAAVSSHELRTPLTAMRTNLEVLST---------LDLPDDQR- 266

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l+ ++r r+++ + l l++ e
CP000325_0 267 ----------KEVLNDVIRTQSRIEATLGALERLAQGELS 296

CP000325_1243: domain 1 of 1, from 276 to 348: score 51.1, E = 3.8e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++fl +++HELRTP+++++ +ae L ++ + e+
CP000325_1 276 ATRQFLVDAAHELRTPIAGMQVAAEQLAS--------SAGQQQED-- 312

peLR.ledpeyreyletilreaerllrLindlLdlsrieag<-*
p++R+ + + +l++a+r rL+ d+Ldlsri+ag
CP000325_1 313 PAARgQ-----YRRASLLLSDARRAGRLVADMLDLSRIDAG 348

CP000325_2172: domain 1 of 1, from 296 to 364: score 41.3, E = 2.4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL + ++++lL++++ + l+e +
CP000325_2 296 ELEQFAYVASHDLQEPLRKVAAFCQLLERRYA------DQLDERGI- 335

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+ + + a+r++ LindlL +sr +
CP000325_2 336 -----------EYIGFAVDGAKRMQVLINDLLSFSRVGRL 364


Histogram of all scores:
score obs exp (one = represents 15 sequences)
----- --- ---
-15 1 0|=
-14 10 0|=
-13 40 3|*==
-12 202 95|======*=======
-11 360 493|======================== *
-10 773 914|==================================================== *
-9 827 944|======================================================== *
-8 801 707|===============================================*======
-7 488 445|=============================*===
-6 280 256|=================*=
-5 152 140|=========*=
-4 103 75|====*==
-3 42 39|==*
-2 37 20|=*=
-1 17 10|*=
0 9 5|*
1 6 2|*
2 1 1|*
3 1 0|=
> 4 10 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 240.3794
P(chi-square) = 2.652e-314

Total sequences searched: 4160

Whole sequence top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: