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Thermotogae
Classification of phyla is from NCBI page
Search:
19 projects found  

2 accessions found for Leptospira borgpetersenii serovar Hardjo-bovis JB197  

Data for CP000350  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000350.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000350_1190 CDS_1625348-1627867 127.1 7.2e-36 2
CP000350_1478 CDS_1988138-1991209 98.1 1.2e-27 1
CP000350_0167 CDS_223413-222022 83.5 1.7e-23 1
CP000350_1087 CDS_1482619-1486314 73.2 1.4e-20 2
CP000350_1968 CDS_2677031-2678419 70.1 1e-19 1
CP000350_1482 CDS_1994911-1993790 63.7 6.7e-18 1
CP000350_0231 CDS_302854-301736 58.2 2.4e-16 1
CP000350_1088 CDS_1486333-1487448 52.6 9.7e-15 1
CP000350_1191 CDS_1627884-1629032 52.4 1.1e-14 1
CP000350_1058 CDS_1447916-1446792 52.1 1.3e-14 1
CP000350_1723 CDS_2312389-2311052 41.9 1e-11 1
CP000350_1257 CDS_1706628-1704838 41.7 1.1e-11 1
CP000350_0528 CDS_731151-729640 33.9 1.9e-09 1
CP000350_2387 CDS_3247433-3248536 33.5 2.5e-09 1
CP000350_0876 CDS_1198899-1201496 33.2 3.1e-09 1
CP000350_0878 CDS_1201931-1203460 30.6 1.7e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000350_1478 1/1 510 575 .. 1 87 [] 98.1 1.2e-27
CP000350_1190 1/2 208 274 .. 1 87 [] 84.2 1e-23
CP000350_0167 1/1 232 300 .. 1 87 [] 83.5 1.7e-23
CP000350_1087 2/2 569 637 .. 1 87 [] 72.5 2.1e-20
CP000350_1968 1/1 238 306 .. 1 87 [] 70.1 1e-19
CP000350_1482 1/1 148 214 .. 1 87 [] 63.7 6.7e-18
CP000350_0231 1/1 149 214 .. 1 87 [] 58.2 2.4e-16
CP000350_1088 1/1 152 220 .. 1 87 [] 52.6 9.7e-15
CP000350_1191 1/1 151 217 .. 1 87 [] 52.4 1.1e-14
CP000350_1058 1/1 149 217 .. 1 87 [] 52.1 1.3e-14
CP000350_1190 2/2 606 674 .. 1 87 [] 42.9 5.3e-12
CP000350_1723 1/1 225 288 .. 1 87 [] 41.9 1e-11
CP000350_1257 1/1 365 437 .. 1 87 [] 41.7 1.1e-11
CP000350_0528 1/1 284 350 .. 1 87 [] 33.9 1.9e-09
CP000350_2387 1/1 144 210 .. 1 87 [] 33.5 2.5e-09
CP000350_0876 1/1 633 700 .. 1 87 [] 33.2 3.1e-09
CP000350_0878 1/1 153 219 .. 1 87 [] 30.6 1.7e-08

Alignments of top-scoring domains:
CP000350_1478: domain 1 of 1, from 510 to 575: score 98.1, E = 1.2e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak++fla++sHE+RTPL++++g+++lL+ t l++eq
CP000350_1 510 AKTDFLAMMSHEIRTPLNGVIGTVSLLEG---------TSLGAEQ-- 545

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
reyl++i+++++ ll L+nd+Ldlsrie+g
CP000350_1 546 ----------REYLDIIKSSGQNLLILLNDILDLSRIESG 575

CP000350_1190: domain 1 of 2, from 208 to 274: score 84.2, E = 1e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks+f+an+sHELRTPLt I+g + +Ll+ d++ s+ q
CP000350_1 208 LKSQFFANVSHELRTPLTLIIGPTRTLLK--------DQKISATQ-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +let++r + ll+ +ndlLdls++eag
CP000350_1 245 ----------RTFLETMERNSYTLLKHVNDLLDLSKLEAG 274

CP000350_0167: domain 1 of 1, from 232 to 300: score 83.5, E = 1.7e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ n+sHEL+TP+t+I+gy+e+Ll+ + ls+e +
CP000350_0 232 IREQFVQNASHELKTPITSIKGYTETLLD--------RLRLSPESHE 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ i r ++r+ r++ d+L+++rie++
CP000350_0 271 ----------KRFLDAISRNTDRMVRIVADMLTITRIENQ 300

CP000350_1087: domain 2 of 2, from 569 to 637: score 72.5, E = 2.1e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++ +++ L + + +l+e+q
CP000350_1 569 YKSEFLANMSHELRTPLNSLLILSKDLAD------NKKKNLDEDQ-- 607

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e ++i+++++ ll Lin++Ldls+ie+g
CP000350_1 608 ----------VESANIIYKSGHDLLVLINEVLDLSKIESG 637

CP000350_1968: domain 1 of 1, from 238 to 306: score 70.1, E = 1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f ++sH+LR P+ +I+g++++Lle++ tel+ee
CP000350_1 238 DLEAFSYSVSHDLRSPIRGILGFSKILLEDYG------TELGEES-- 276

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+++++i++++e + +Li+dlL++sr++
CP000350_1 277 ----------RRIVNIIIQSSENMGELIDDLLEYSRLGRR 306

CP000350_1482: domain 1 of 1, from 148 to 214: score 63.7, E = 6.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + + a+++HE+++PL +++ yae++ + + + +
CP000350_1 148 AIGTLSAGVAHEINNPLMGVINYAEMMFN---------GIENGNPL- 184

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y +ilre++r+++++ d+L+++r e +
CP000350_1 185 ----------RKYAGIILREGNRISEIVKDMLTFTRVEKE 214

CP000350_0231: domain 1 of 1, from 149 to 214: score 58.2, E = 2.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+++l ++ H+L++P+++I+g++elL+e ++ +
CP000350_0 149 SKNRLLTTVVHDLKNPINGILGLIELLKE---------QTDNQNR-- 184

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+l+ + r+a+ l++i+dlL+++ +e++
CP000350_0 185 ----------TELLNMMFRAADKSLNIIQDLLQIAEMENE 214

CP000350_1088: domain 1 of 1, from 152 to 220: score 52.6, E = 9.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f ++sH+L+ PL +Irgy+++L+e++ ++l+ee
CP000350_1 152 ELDAFCYSVSHDLKAPLRGIRGYTKILKEDYK------DKLDEEG-- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ + ++ Li+ lL ls+++
CP000350_1 191 ----------ERILGLVIENSLKMSTLIDSLLLLSKLGKK 220

CP000350_1191: domain 1 of 1, from 151 to 217: score 52.4, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++ +++HE+++PL aI+ ya ++ + +e +++++
CP000350_1 151 AMGVMAGTMAHEINNPLIAISEYAAIIAK---------GEVDADKT- 187

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++i++e+ r++ + +lL +sr + g
CP000350_1 188 ----------KQLASKIRDESARISTIMKNLLRFSRDDKG 217

CP000350_1058: domain 1 of 1, from 149 to 217: score 52.1, E = 1.3e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+++++HEL++PLt+++++++ Ll++l t ++e
CP000350_1 149 SLGIFISGVAHELNNPLTGMSLTLQSLLNNL-------TSIDPEF-- 186

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+r+ l+ +++++ r ++ d+ +++ +
CP000350_1 187 ---------FRKRLDMMKEDLTRAAMIVTDIISFAKPDRL 217

CP000350_1190: domain 2 of 2, from 606 to 674: score 42.9, E = 5.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f ++sH+LR P+ +I g++++ le++ ++++++e
CP000350_1 606 DMESFSYSVSHDLRAPILGIEGFLQIVLEDF------SEKMDSEA-- 644

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l+t+++ + ++++Li+dlL + +i
CP000350_1 645 ----------LRLLKTVQKNVIYMNNLIQDLLNFHKISKI 674

CP000350_1723: domain 1 of 1, from 225 to 288: score 41.9, E = 1e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++ HE++ PL+++++ +el+ e +++ +
CP000350_1 225 YVENYVQSMTHEIKSPLSSLLASSELIIE------------NPDRL- 258

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ i+ e++r++ +++ lL+ls +e++
CP000350_1 259 ----------EFLISNIQLEGKRIQTILEKLLELSSLENQ 288

CP000350_1257: domain 1 of 1, from 365 to 437: score 41.7, E = 1.1e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a e + ++HE+++PLt I++ ae +++++ + eq
CP000350_1 365 AWKEVAQRMAHEIKNPLTPIQLSAERIRRKM-------KSENKEQ-- 402

peLRledpeyreyl....etilreaerllrLindlLdlsrieag<-*
+ e+++++++ti+++++ l++L+n++ d++r+ ++
CP000350_1 403 ---------FYEIVstgtDTIIKQVRVLEHLVNEFSDFARMPTP 437

CP000350_0528: domain 1 of 1, from 284 to 350: score 33.9, E = 1.9e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s +++++ HE+++ LtaI+g++e+++ ++++e+ r
CP000350_0 284 FLSVLASSIGHEINNSLTAIQGHIEIAKL---------PDATEQIR- 320

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +++ ++ l+ L n+lL+l + ++
CP000350_0 321 ----------QKTIQITWGQLIKLQTLTNNLLQLGKPGES 350

CP000350_2387: domain 1 of 1, from 144 to 210: score 33.5, E = 2.5e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks++l+ l+H+LRTPL I+ +++l ++ +e ++ ++
CP000350_2 144 IKSQLLSILAHDLRTPLIQIISLISLFKN---------EEIPSIDL- 180

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l+++ +++ +Li++ L + +
CP000350_2 181 ----------HQHLSKLNIQTHLTIDLIDNTLNWVKTNSK 210

CP000350_0876: domain 1 of 1, from 633 to 700: score 33.2, E = 3.1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +sH+L PL I+++ + Ll++ ++l++e
CP000350_0 633 DLEDFAFIASHDLQEPLRKIKAFGDRLLKRN-------SNLDSES-- 670

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+++ +a+rl++Li+ lL +sri +
CP000350_0 671 ----------VDYLQRMFFSAHRLSNLIEGLLSYSRIKSR 700

CP000350_0878: domain 1 of 1, from 153 to 219: score 30.6, E = 1.7e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
s+f +++H++++ L++I +++++L++ + ++ +++
CP000350_0 153 TISQFSGGIAHDFNNILNVIVANLDMLEM---------QCKNQPDV- 189

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++++ r + lL +sr ++
CP000350_0 190 ----------LNRIRSAQNAVMRGAEVNKKLLNFSRKQSL 219


Histogram of all scores:
score obs exp (one = represents 10 sequences)
----- --- ---
-14 6 0|=
-13 29 1|*==
-12 109 60|=====*=====
-11 269 313|=========================== *
-10 463 581|=============================================== *
-9 539 600|====================================================== *
-8 453 449|============================================*=
-7 339 283|============================*=====
-6 176 163|================*=
-5 100 89|========*=
-4 51 47|====*=
-3 47 25|==*==
-2 20 13|=*
-1 17 6|*=
0 6 3|*
1 0 1|*
2 0 0|
> 3 21 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 125.8674
P(chi-square) = 1.191e-21

Total sequences searched: 2645

Whole sequence top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 17
Satisfying E cutoff: 17
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: