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Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
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Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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76 projects found  

4 accessions found for Cupriavidus metallidurans CH34  

Data for CP000352  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000352.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000352_2172 CDS_2388023-2386671 87.3 1.9e-24 1
CP000352_2147 CDS_2351526-2353973 76.7 2e-21 1
CP000352_1174 CDS_1284914-1286428 70.4 1.2e-19 1
CP000352_0041 CDS_44406-47309 70.0 1.5e-19 1
CP000352_0464 CDS_494681-493107 66.1 1.9e-18 1
CP000352_2053 CDS_2233642-2232479 64.9 4.1e-18 1
CP000352_3522 CDS_3833371-3835053 63.9 8.2e-18 1
CP000352_1745 CDS_1901477-1902886 63.4 1.1e-17 1
CP000352_2992 CDS_3261256-3262587 61.6 3.7e-17 1
CP000352_3077 CDS_3351288-3349252 61.1 4.9e-17 2
CP000352_2868 CDS_3134356-3132458 54.7 3.3e-15 1
CP000352_3570 CDS_3892338-3890851 54.4 4e-15 1
CP000352_1648 CDS_1787430-1785985 53.9 5.5e-15 1
CP000352_3002 CDS_3274783-3273371 53.3 8.2e-15 1
CP000352_0516 CDS_552515-553798 52.8 1.1e-14 1
CP000352_1623 CDS_1755750-1754314 48.8 1.5e-13 1
CP000352_1941 CDS_2118232-2119581 45.2 1.6e-12 1
CP000352_1692 CDS_1839378-1840331 45.1 1.8e-12 1
CP000352_3546 CDS_3862550-3860067 44.6 2.3e-12 1
CP000352_2374 CDS_2596769-2595681 43.7 4.3e-12 1
CP000352_3462 CDS_3757480-3756167 39.7 5.7e-11 1
CP000352_2937 CDS_3208823-3207687 37.7 2.2e-10 1
CP000352_2938 CDS_3210215-3208827 35.4 9.5e-10 1
CP000352_0589 CDS_633967-632195 34.5 1.7e-09 1
CP000352_1195 CDS_1312041-1309429 32.7 5.4e-09 1
CP000352_0229 CDS_242959-244965 29.2 5.4e-08 1
CP000352_0136 CDS_142426-141047 27.4 1.8e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000352_2172 1/1 206 272 .. 1 87 [] 87.3 1.9e-24
CP000352_2147 1/1 330 395 .. 1 87 [] 76.7 2e-21
CP000352_1174 1/1 268 336 .. 1 87 [] 70.4 1.2e-19
CP000352_0041 1/1 729 796 .. 1 87 [] 70.0 1.5e-19
CP000352_0464 1/1 290 355 .. 1 87 [] 66.1 1.9e-18
CP000352_2053 1/1 163 228 .. 1 87 [] 64.9 4.1e-18
CP000352_3522 1/1 283 348 .. 1 87 [] 63.9 8.2e-18
CP000352_1745 1/1 243 309 .. 1 87 [] 63.4 1.1e-17
CP000352_2992 1/1 223 288 .. 1 87 [] 61.6 3.7e-17
CP000352_3077 2/2 422 489 .. 1 87 [] 59.2 1.7e-16
CP000352_2868 1/1 266 331 .. 1 87 [] 54.7 3.3e-15
CP000352_3570 1/1 257 330 .. 1 87 [] 54.4 4e-15
CP000352_1648 1/1 255 320 .. 1 87 [] 53.9 5.5e-15
CP000352_3002 1/1 249 314 .. 1 87 [] 53.3 8.2e-15
CP000352_0516 1/1 218 276 .. 1 87 [] 52.8 1.1e-14
CP000352_1623 1/1 241 306 .. 1 87 [] 48.8 1.5e-13
CP000352_1941 1/1 236 295 .. 1 87 [] 45.2 1.6e-12
CP000352_1692 1/1 56 126 .. 1 87 [] 45.1 1.8e-12
CP000352_3546 1/1 585 657 .. 1 87 [] 44.6 2.3e-12
CP000352_2374 1/1 224 288 .. 1 87 [] 43.7 4.3e-12
CP000352_3462 1/1 232 290 .. 1 87 [] 39.7 5.7e-11
CP000352_2937 1/1 142 214 .. 1 87 [] 37.7 2.2e-10
CP000352_2938 1/1 240 308 .. 1 87 [] 35.4 9.5e-10
CP000352_0589 1/1 360 428 .. 1 87 [] 34.5 1.7e-09
CP000352_1195 1/1 636 706 .. 1 87 [] 32.7 5.4e-09
CP000352_0229 1/1 440 503 .. 1 82 [. 29.2 5.4e-08
CP000352_0136 1/1 223 292 .. 1 87 [] 27.4 1.8e-07

Alignments of top-scoring domains:
CP000352_2172: domain 1 of 1, from 206 to 272: score 87.3, E = 1.9e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt++ g++e+ ++ + see+r
CP000352_2 206 MRRDFVANVSHELKTPLTVLTGFLETVRD---------LPVSEEDR- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y++ +l ++ r++++++dlL l+++e+
CP000352_2 243 ----------KRYIDMMLVQSMRMQHIVEDLLALAKLESD 272

CP000352_2147: domain 1 of 1, from 330 to 395: score 76.7, E = 2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ksefla +sHE+RTP++a+ g++elL + ++ + +
CP000352_2 330 VKSEFLAIMSHEIRTPISAVVGALELLDR---------EDNNTPR-- 365

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re+l++++++a++ll+ +n++Ld+s i +g
CP000352_2 366 ----------RELLHRARESADSLLAVLNNVLDYSSISTG 395

CP000352_1174: domain 1 of 1, from 268 to 336: score 70.4, E = 1.2e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++an+sH+LRTPLt++ gy+e+L ++ ++ls+e+r
CP000352_1 268 ERREMVANISHDLRTPLTSLHGYLETLSLKA-------DKLSAEER- 306

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl ++l ++ L + l +l+r+e+g
CP000352_1 307 ----------QRYLAIALAQSAKVGGLAQSLFELARLEHG 336

CP000352_0041: domain 1 of 1, from 729 to 796: score 70.0, E = 1.5e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s +la++sH+LRTPLt+++g+ae+L++ + +l++
CP000352_0 729 LRSSLLAAVSHDLRTPLTGLIGMAETLQR-------AEMPLPASV-- 766

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +e ++ +a+r++ ++ +lLd++r+++
CP000352_0 767 ----------AETVEAMRVQAQRMRTMVVNLLDMARLQHH 796

CP000352_0464: domain 1 of 1, from 290 to 355: score 66.1, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ael+++ e+s+e++
CP000352_0 290 TQKRFIADAAHQMKTPLAGLRMQAELAQR----------EQSPEEL- 325

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l i +++r +L+ +lL l+r+e+
CP000352_0 326 ----------HRSLAQIAGSSKRTAHLVTQLLSLARMENL 355

CP000352_2053: domain 1 of 1, from 163 to 228: score 64.9, E = 4.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a e+++nl+HE+++PL +Irg+a+lL+ el+e +
CP000352_2 163 ANKELIRNLAHEIKNPLGGIRGAAQLLEF----------ELPERAL- 198

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey+++i++e++rl+ L+++lL+ r +
CP000352_2 199 ----------REYTQVIIKESDRLQTLVDRLLEPHRHPHI 228

CP000352_3522: domain 1 of 1, from 283 to 348: score 63.9, E = 8.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLta++++a+ + + + s e +
CP000352_3 283 AQRKFIADAAHQLRTPLTAVKLHADRAVD----------ADSLEVA- 318

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++l+ ++ +a+r rL n+lL l+r+e g
CP000352_3 319 ----------RQALREVQTAADRAVRLSNQLLSLARAEPG 348

CP000352_1745: domain 1 of 1, from 243 to 309: score 63.4, E = 1.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f a+l+H++RTP+t ++g ++++l +++s e+
CP000352_1 243 RLSQFSADLAHDFRTPITNLLGQTQVALS---------SDRSIEE-- 278

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ +l + +e erl+r+i+++L l+r+++
CP000352_1 279 ---------YQSLLVSNVEEYERLSRMIENMLFLARADNA 309

CP000352_2992: domain 1 of 1, from 223 to 288: score 61.6, E = 3.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a+++HELR PLta+++ ae L e +e+s+
CP000352_2 223 SQRRFVADAAHELRSPLTAMSLQAERLAE---------AEMSSVA-- 258

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re l ++++ +er ++L+++lL+l+++++
CP000352_2 259 ----------RERLTVLRQGIERGRSLLDQLLTLAKAQSA 288

CP000352_3077: domain 2 of 2, from 422 to 489: score 59.2, E = 1.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a+++H++R+PL+aI+ + elL + + + + +
CP000352_3 422 AMGRLVASVAHQIRNPLAAISQANELLADSG-------GGEGNID-- 459

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l++i + ++rl++ i+d+L+lsr
CP000352_3 460 ----------ARLLRIISDNVRRLDQVISDVLQLSRRPRT 489

CP000352_2868: domain 1 of 1, from 266 to 331: score 54.7, E = 3.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+fla++sH+LR+P++a+ +++e+L++ ++s+
CP000352_2 266 EKSRFLAAASHDLRQPVHALVMLVEALRA---------RNQSSSL-- 301

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++e + ++ ++ L + lLdls++e
CP000352_2 302 ----------HPLVEQVAAGTQTIDLLFRSLLDLSKLEGR 331

CP000352_3570: domain 1 of 1, from 257 to 330: score 54.4, E = 4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+ +f+a+++H+LRTPL+ +++ ae ++++ld +++g++++ +
CP000352_3 257 AQAQFIADAAHQLRTPLAILKTQAEFAQRQLD-TFGGEGAAHSGA-- 300

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++ i +++e+ r+ n+lL l+r ++
CP000352_3 301 ----------AEAVGGIVKQLEQAARMTNQLLALARVRQH 330

CP000352_1648: domain 1 of 1, from 255 to 320: score 53.9, E = 5.5e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + +l HE++ PL+aI g+aelL+e +++ +r
CP000352_1 255 YVEHYIHTLTHEMKSPLAAIGGAAELLQE----------DMPTADR- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+++a+rl+ Li+ lL l+ e+
CP000352_1 291 ----------QRFLGNIRSQAQRLDLLIRKLLALAEVEQR 320

CP000352_3002: domain 1 of 1, from 249 to 314: score 53.3, E = 8.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f ++++HELRTPL+ Ir ae +l ++++ +
CP000352_3 249 RERRFSRDVAHELRTPLAEIRISAENALI----------DADPTRI- 284

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ +++++ r++r ++ lL l+r+e+g
CP000352_3 285 ----------QRALNAMIQASSRMQRSVDTLLLLARLESG 314

CP000352_0516: domain 1 of 1, from 218 to 276: score 52.8, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +la+++H+L+TPL+ +r+ ae+L +
CP000352_0 218 ERNTMLAGIAHDLKTPLARLRLRAEMLSD------------------ 246

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + r++e+++++++++L++++ ++
CP000352_0 247 ----------PKAAAGVTRDVESMSAIVEQFLTFAQSSEP 276

CP000352_1623: domain 1 of 1, from 241 to 306: score 48.8, E = 1.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+L+TPL+ I++ +el+l+ e++ + +
CP000352_1 241 GRKRFFADAAHQLKTPLAIIQAESELALR----------EKDLPSV- 276

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +e+++ ++++ + + +lL lsr+e
CP000352_1 277 ----------RAHVERLHGSVQQAAKEVAQLLSLSRLEPD 306

CP000352_1941: domain 1 of 1, from 236 to 295: score 45.2, E = 1.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPLt +r+ +e+ ++ + +
CP000352_1 236 DRVVMLAGISHDLRTPLTRLRLETEM------------SPVDNVT-- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ++e+++++i ++L ++r +++
CP000352_1 269 -------------RDAMIADIEQMDAIIGQFLNYARPGQE 295

CP000352_1692: domain 1 of 1, from 56 to 126: score 45.1, E = 1.8e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++ +++HEL++PLtaI +a++++e ++ ++++++ ++
CP000352_1 56 GMNELAGSIAHELNQPLTAITSNAQAARE-----YLASGPCDPAEV- 96

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re+l+ i +a r ++++++++ l ea+
CP000352_1 97 ----------REILDDIVADASRASEIVRRVRALILGEAP 126

CP000352_3546: domain 1 of 1, from 585 to 657: score 44.6, E = 2.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l +++ ++ ++e +
CP000352_3 585 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL---SPKLETSDAEVL- 627

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ti +++ + r+++d++d++r
CP000352_3 628 ----------KRGAATIVNQVAAMKRMVDDFRDYARTPPA 657

CP000352_2374: domain 1 of 1, from 224 to 288: score 43.7, E = 4.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+ +++HELRTPLt+I +++++++ +e +e
CP000352_2 224 SQRAFTDAAAHELRTPLTVIDTHLQVARI---------SEGDEVA-- 259

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++++ ++rl+r +++++ l+r+e+
CP000352_2 260 -----------SSLSSAEEGVKRLRRTLDQMMILARAETS 288

CP000352_3462: domain 1 of 1, from 232 to 290: score 39.7, E = 5.7e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+fla++sH+LRTPLt +++ +e +++
CP000352_3 232 QQSRFLAAVSHDLRTPLTRMSLRIERIED------------------ 260

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++ ++ Li+ L + r +
CP000352_3 261 ----------NNVRYRLRQDLAEMNGLIDATLYYLRERDD 290

CP000352_2937: domain 1 of 1, from 142 to 214: score 37.7, E = 2.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e la l+HEL+TPL+aI +a +++++ +e + + +
CP000352_2 142 AIDETLAFLAHELNTPLAAIANFARGIEARVA------GEYNQQRN- 181

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ ++ +++ a+++l+ ++ +L+ r ag
CP000352_2 182 -------AEIGRAAGAMHDNAQYCLAVLSSFLQSVRSSAG 214

CP000352_2938: domain 1 of 1, from 240 to 308: score 35.4, E = 9.5e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++a+l HE ++P++ ++++e++ e +++ +
CP000352_2 240 AIGTLAAGLLHEVNNPVNFCLMAIEVAME---------EPAAKSE-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
p+++e l +++ +r++++++dl +++ g
CP000352_2 276 -------PGIQECLVDAKQGMQRIQHIVSDLKTFAYRKPG 308

CP000352_0589: domain 1 of 1, from 360 to 428: score 34.5, E = 1.7e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +++ a+++HEL++PLta+r+++ ++l + + ++
CP000352_0 360 AVGQMSAGIAHELNQPLTALRTLSGNTGKFL-------ERGDYATV- 398

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l++i +er+ r+ l ++r +
CP000352_0 399 ----------QHNLDKIVGLVERMGRITGALKSFARNPSA 428

CP000352_1195: domain 1 of 1, from 636 to 706: score 32.7, E = 5.4e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++l+HEL++PL+aI y+ + ++l +++ ++e+++
CP000352_1 636 TMGEMASSLAHELNQPLAAINNYCMGAVARL-----HSGRSTPEDLI 677

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
p le+ +a r +i++++ + + ++
CP000352_1 678 PV-----------LEKTSAQAVRAGTIISRIRGFVKRSQP 706

CP000352_0229: domain 1 of 1, from 440 to 503: score 29.2, E = 5.4e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+a+r++++ + l++++ l++ +
CP000352_0 440 ALGQMAAGITHELNQPLAALRTFSDNTRV-----LLERGQLDAAT-- 479

peLRledpeyreyletilreaerllrLindlLdls<-*
l+ i + +er+ ++ +l ++
CP000352_0 480 -----------GNLSAIADLTERMGKITGQLKLFA 503

CP000352_0136: domain 1 of 1, from 223 to 292: score 27.4, E = 1.8e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++ +a+++HE+ TPL+++ a L+++++ t++s+ ++
CP000352_0 223 ALNDQAAAVAHEIGTPLATLAVIAGELRADAE-----NTNRSDTPVA 264

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + l+t+++++e +++++ +l r++++
CP000352_0 265 DY--------QADLRTMEQQLELCRSILARL----RADHE 292


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-14 6 0|=
-13 30 2|*==
-12 134 82|======*====
-11 315 426|========================= *
-10 572 791|============================================ *
-9 751 817|==========================================================*
-8 647 612|===============================================*==
-7 462 385|=============================*======
-6 304 222|=================*======
-5 144 121|=========*==
-4 106 65|====*====
-3 47 34|==*=
-2 27 18|=*=
-1 13 9|*
0 6 4|*
1 9 2|*
> 2 28 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 215.4460
P(chi-square) = 8.68e-310

Total sequences searched: 3601

Whole sequence top hits:
tophits_s report:
Total hits: 27
Satisfying E cutoff: 27
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 27
Satisfying E cutoff: 27
Total memory: 31K


Acknowledgements:

This research is funded by:

Developed by: