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Thermotogae
Classification of phyla is from NCBI page
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76 projects found  

4 accessions found for Cupriavidus metallidurans CH34  

Data for CP000353  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000353.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000353_1338 CDS_1487956-1484588 94.9 8.7e-27 1
CP000353_0634 CDS_697161-701417 89.9 2.3e-25 1
CP000353_1341 CDS_1492833-1489978 83.3 1.6e-23 1
CP000353_2082 CDS_2320130-2323252 83.2 1.8e-23 1
CP000353_2096 CDS_2334195-2336549 82.0 3.8e-23 1
CP000353_0366 CDS_408380-404910 79.2 2.5e-22 1
CP000353_0633 CDS_694898-696943 79.0 2.8e-22 1
CP000353_1001 CDS_1109252-1106301 77.8 6.1e-22 1
CP000353_0980 CDS_1083349-1079420 77.1 9.5e-22 1
CP000353_2045 CDS_2284935-2286323 76.0 1.9e-21 1
CP000353_1704 CDS_1897012-1898427 64.0 4.8e-18 1
CP000353_1230 CDS_1365930-1367705 62.7 1.1e-17 1
CP000353_0421 CDS_459328-460659 61.6 2.4e-17 1
CP000353_1352 CDS_1508200-1506869 61.6 2.4e-17 1
CP000353_2169 CDS_2409145-2407814 60.1 6.3e-17 1
CP000353_1205 CDS_1336702-1338075 59.8 7.7e-17 1
CP000353_1699 CDS_1888924-1890366 59.2 1.1e-16 1
CP000353_0844 CDS_915252-916694 57.7 2.9e-16 1
CP000353_1694 CDS_1886116-1884527 53.1 5.9e-15 1
CP000353_1765 CDS_1971467-1972819 51.3 1.9e-14 1
CP000353_1681 CDS_1870158-1864924 34.5 1.1e-09 1
CP000353_0316 CDS_345399-346826 34.4 1.2e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000353_1338 1/1 515 580 .. 1 87 [] 94.9 8.7e-27
CP000353_0634 1/1 797 862 .. 1 87 [] 89.9 2.3e-25
CP000353_1341 1/1 369 434 .. 1 87 [] 83.3 1.6e-23
CP000353_2082 1/1 645 711 .. 1 87 [] 83.2 1.8e-23
CP000353_2096 1/1 310 375 .. 1 87 [] 82.0 3.8e-23
CP000353_0366 1/1 535 600 .. 1 87 [] 79.2 2.5e-22
CP000353_0633 1/1 430 495 .. 1 87 [] 79.0 2.8e-22
CP000353_1001 1/1 388 453 .. 1 87 [] 77.8 6.1e-22
CP000353_0980 1/1 797 862 .. 1 87 [] 77.1 9.5e-22
CP000353_2045 1/1 238 304 .. 1 87 [] 76.0 1.9e-21
CP000353_1704 1/1 243 309 .. 1 87 [] 64.0 4.8e-18
CP000353_1230 1/1 227 292 .. 1 87 [] 62.7 1.1e-17
CP000353_0421 1/1 223 288 .. 1 87 [] 61.6 2.4e-17
CP000353_1352 1/1 223 288 .. 1 87 [] 61.6 2.4e-17
CP000353_2169 1/1 223 288 .. 1 87 [] 60.1 6.3e-17
CP000353_1205 1/1 235 300 .. 1 87 [] 59.8 7.7e-17
CP000353_1699 1/1 230 295 .. 1 87 [] 59.2 1.1e-16
CP000353_0844 1/1 253 319 .. 1 87 [] 57.7 2.9e-16
CP000353_1694 1/1 297 365 .. 1 87 [] 53.1 5.9e-15
CP000353_1765 1/1 228 293 .. 1 87 [] 51.3 1.9e-14
CP000353_1681 1/1 1517 1587 .. 1 87 [] 34.5 1.1e-09
CP000353_0316 1/1 247 309 .. 1 87 [] 34.4 1.2e-09

Alignments of top-scoring domains:
CP000353_1338: domain 1 of 1, from 515 to 580: score 94.9, E = 8.7e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL++++g +elL+ ++l++ q
CP000353_1 515 AKSAFLATMSHEIRTPLNGMLGSIELLEV---------SALDAAQ-- 550

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ le+++++a++l ++ind+Ld+s+ieag
CP000353_1 551 ----------RDQLEVMQQSAQSLIQIINDVLDFSKIEAG 580

CP000353_0634: domain 1 of 1, from 797 to 862: score 89.9, E = 2.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fla++sHE+RTP+++I+g++elL++ t+l++eq
CP000353_0 797 AKDSFLAMMSHEIRTPMNGILGLIELLQR---------TPLTAEQ-- 832

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ + ++++ l r+++d+Ld++++eag
CP000353_0 833 ----------QRMVALAGESGQALGRILDDILDYAKLEAG 862

CP000353_1341: domain 1 of 1, from 369 to 434: score 83.3, E = 1.6e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +++g++elL t+l++ q
CP000353_1 369 AKSIFLAAMSHEMRTPLYGMLGTLELLSL---------TALDDRQ-- 404

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ + ti+ ++ ll++i+dlLd+++ e g
CP000353_1 405 ----------RQDVGTIQTSSATLLSIIDDLLDYTKFEGG 434

CP000353_2082: domain 1 of 1, from 645 to 711: score 83.2, E = 1.8e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTP++aI+g++el l d l++++
CP000353_2 645 AKSAFLASISHEIRTPMNAILGMLELTLQ--------DKRLPDDD-- 681

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +et++++a++l Li+d+Ld s++eag
CP000353_2 682 ----------RLQVETAQESAKSLIGLIDDILDASKMEAG 711

CP000353_2096: domain 1 of 1, from 310 to 375: score 82.0, E = 3.8e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTPL+++++ ++lL+e +els q
CP000353_2 310 AKSRFLATMSHEIRTPLATVIASLDLLRE---------SELSTHQ-- 345

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re l+ ++++a+ ll+++ d+Ld+srieag
CP000353_2 346 ----------REELDLADHSAKLLLEILGDILDFSRIEAG 375

CP000353_0366: domain 1 of 1, from 535 to 600: score 79.2, E = 2.5e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+s f+a++sHE+RTPL+a++g++elL + ++ e +
CP000353_0 535 ARSNFFAAMSHEIRTPLNALLGNLELLGR---------SAGLEAH-- 570

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l+ +++++e l+r++nd+Ld+s+i+ag
CP000353_0 571 ----------ATRLRALQSSSEGLRRIVNDILDFSKIDAG 600

CP000353_0633: domain 1 of 1, from 430 to 495: score 79.0, E = 2.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks fla++sHE+RTPL +I+g++el + ++ls+eq
CP000353_0 430 TKSSFLAMMSHEIRTPLQGILGLLELVEY---------SPLSAEQ-- 465

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ ++ + ++++ l+++++d+Ld+++++ag
CP000353_0 466 ----------RRQVRLASEAGQALRQILDDVLDYAKMDAG 495

CP000353_1001: domain 1 of 1, from 388 to 453: score 77.8, E = 6.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+ f+a++sHE+RTPL++++g+ el + ++l+++q
CP000353_1 388 ARVAFFASMSHEIRTPLASLLGNMELVAR---------GPLPPDQ-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + ++ +ae ll+++nd+Ld+sri+ g
CP000353_1 424 ----------RTRVGAMQVSAEGLLQIVNDVLDFSRIDVG 453

CP000353_0980: domain 1 of 1, from 797 to 862: score 77.1, E = 9.5e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fla++sHE+RTP+++++g+aelL t l++eq
CP000353_0 797 AKDSFLAMMSHEIRTPMNGVLGLAELLSH---------TSLTPEQ-- 832

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++a ll++++d+Ld+s+ieag
CP000353_0 833 ----------SATVGMMGDSASALLQILDDILDYSKIEAG 862

CP000353_2045: domain 1 of 1, from 238 to 304: score 76.0, E = 1.9e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++sef ++l+HELRTPLt +++ ++++l +++++e+
CP000353_2 238 RLSEFSSDLAHELRTPLTNLMTQTQVALS---------QPRDAEK-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yre+l + +e++rl+r+++d+L l+++e+g
CP000353_2 274 ---------YREILASNAEELQRLSRMVSDMLYLAKMEHG 304

CP000353_1704: domain 1 of 1, from 243 to 309: score 64.0, E = 4.8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELR PL+ +r+ +e+ l+ ++ +++
CP000353_1 243 QQRRFTADASHELRSPLSRLRTEIEVTLR---------RPRESQE-- 278

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y + l++ l+e+ rl rLi++lL l+r +ag
CP000353_1 279 ---------YVDTLRSCLDEVGRLTRLIEELLMLARFDAG 309

CP000353_1230: domain 1 of 1, from 227 to 292: score 62.7, E = 1.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sH+LR+PL+a+ +++ L + t+l++ q
CP000353_1 227 AKSVFLASASHDLRQPLHALGLFLVSLGR---------TPLDAHQ-- 262

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++l+ i+ ++ ++++n lLd+s++eag
CP000353_1 263 ----------RQLLDHIEASSGAAREMLNTLLDFSKLEAG 292

CP000353_0421: domain 1 of 1, from 223 to 288: score 61.6, E = 2.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a+++HELR PLta+++ ae L e +e+s+
CP000353_0 223 SQRRFVADAAHELRSPLTAMSLQAERLAE---------AEMSSVA-- 258

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re l ++++ +er ++L+++lL+l+++++
CP000353_0 259 ----------RERLTVLRQGIERGRSLLDQLLTLAKAQSA 288

CP000353_1352: domain 1 of 1, from 223 to 288: score 61.6, E = 2.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a+++HELR PLta+++ ae L e +e+s+
CP000353_1 223 SQRRFVADAAHELRSPLTAMSLQAERLAE---------AEMSSVA-- 258

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re l ++++ +er ++L+++lL+l+++++
CP000353_1 259 ----------RERLTVLRQGIERGRSLLDQLLTLAKAQSA 288

CP000353_2169: domain 1 of 1, from 223 to 288: score 60.1, E = 6.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++H LRTPL+a+++ a+l ++ + ++e r
CP000353_2 223 TQRAFVADAAHALRTPLAALQLQAQLVER----------AENAEAR- 258

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++ +++ +erl +L+ +lL+l+r e g
CP000353_2 259 ----------QEAVGQLRQGLERLTHLVAQLLTLARQEPG 288

CP000353_1205: domain 1 of 1, from 235 to 300: score 59.8, E = 7.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++a+++HELRTPL+a+++ e++++ ++ + e
CP000353_1 235 HERRLTADAAHELRTPLAALKAQWEVARR---------SDDPTER-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ++ ++ ++rL+++lL++sr+e +
CP000353_1 271 ----------SRAAANVEAGIDGMSRLVSQLLTMSRLEDE 300

CP000353_1699: domain 1 of 1, from 230 to 295: score 59.2, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a+++HELR P+ta+++ ae L++ te++e
CP000353_1 230 MQRRFVADAAHELRSPMTALSLQAERLER---------TEMPEAA-- 265

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l t++r +er ++L+++lL l+r+++
CP000353_1 266 ----------RTRLATLRRGIERSRALLEQLLSLARAQSA 295

CP000353_0844: domain 1 of 1, from 253 to 319: score 57.7, E = 2.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+l+H++RTP++ + g +++ l+ + +++ +
CP000353_0 253 RLSTFSADLAHDFRTPISNLVGQTQVTLA---------QRRTAAE-- 288

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ +le+ l+e erl+r+i+++L l+r+++
CP000353_0 289 ---------YESLLESNLEEYERLSRMIENMLFLARADNA 319

CP000353_1694: domain 1 of 1, from 297 to 365: score 53.1, E = 5.9e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f++++sHE+RTPLt+I gya+ L + ++ls e +
CP000353_1 297 LQRNFVSMVSHEFRTPLTVIDGYAQRLSH-------IKPPLSLEAV- 335

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ++i+ +++r+ +Li+d+L s+
CP000353_1 336 ----------QDRSSRIRAAVRRMTALIEDMLGASQVLDL 365

CP000353_1765: domain 1 of 1, from 228 to 293: score 51.3, E = 1.9e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+an +HELRTP++a ++ ++ L++ +++ +++
CP000353_1 228 AERSFTANSAHELRTPIAAALAQTQRLKA----------DMPTDDM- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++ ++++++ l rL + l++l+++e+g
CP000353_1 264 ----------RERVQNVEHSLRTLARLSESLMQLAKAENG 293

CP000353_1681: domain 1 of 1, from 1517 to 1587: score 34.5, E = 1.1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a+++HE ++PLtaI + +++ l++l+ +++ + ++
CP000353_1 1517 VMGTLAASIAHEVNQPLTAIVASVDASLRWLN-----RATPNLGEV- 1557

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l i++ + r ++i+ l+ l+r
CP000353_1 1558 ----------QDGLAHIRKNGLRAAEIIRALRALARQTPS 1587

CP000353_0316: domain 1 of 1, from 247 to 309: score 34.4, E = 1.2e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +fl +++H+LRT Lt +rg+++ + + ++
CP000353_0 247 NQKRFLDDAAHQLRTSLTLVRGHVDQRIR-------------ASDH- 279

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l ++ +++r rL n+lL+l+r + g
CP000353_0 280 ----------GGDLAEVKAAIDRTVRLTNQLLTLARTGDG 309


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-14 2 0|=
-13 14 1|*=
-12 94 52|======*=====
-11 181 274|======================= *
-10 390 508|================================================= *
-9 445 525|======================================================== *
-8 404 393|=================================================*=
-7 301 247|==============================*=======
-6 195 142|=================*=======
-5 118 78|=========*=====
-4 65 41|=====*===
-3 40 22|==*==
-2 16 11|=*
-1 15 6|*=
0 1 3|*
1 4 1|*
2 1 0|=
3 1 0|=
> 4 26 -|====


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 196.7736
P(chi-square) = 3.472e-36

Total sequences searched: 2313

Whole sequence top hits:
tophits_s report:
Total hits: 22
Satisfying E cutoff: 22
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 22
Satisfying E cutoff: 22
Total memory: 29K


Acknowledgements:

This research is funded by:

Developed by: