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Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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7 projects found  

3 accessions found for Deinococcus geothermalis DSM 11300  

Data for CP000359  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000359.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000359_2086 CDS_2207240-2203818 126.0 1.4e-35 2
CP000359_2305 CDS_2438361-2436787 87.5 1.1e-24 1
CP000359_1262 CDS_1351283-1348458 68.0 3.5e-19 1
CP000359_1261 CDS_1348461-1347211 55.6 1.2e-15 1
CP000359_1512 CDS_1612653-1611340 53.6 4.4e-15 1
CP000359_0906 CDS_970075-971241 52.5 9.1e-15 1
CP000359_0128 CDS_119442-118468 50.1 4.2e-14 1
CP000359_0087 CDS_82042-83121 49.0 8.6e-14 1
CP000359_2169 CDS_2298569-2296437 46.5 4.4e-13 1
CP000359_2138 CDS_2261532-2259220 45.5 8.3e-13 1
CP000359_2204 CDS_2335125-2333683 31.0 1.1e-08 1
CP000359_1616 CDS_1728792-1729865 29.8 2.4e-08 1
CP000359_1549 CDS_1658519-1657272 27.3 1.2e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000359_2305 1/1 293 359 .. 1 87 [] 87.5 1.1e-24
CP000359_2086 1/2 350 418 .. 1 87 [] 78.5 3.7e-22
CP000359_1262 1/1 718 786 .. 1 87 [] 68.0 3.5e-19
CP000359_1261 1/1 189 251 .. 1 87 [] 55.6 1.2e-15
CP000359_1512 1/1 207 271 .. 1 87 [] 53.6 4.4e-15
CP000359_0906 1/1 152 218 .. 1 87 [] 52.5 9.1e-15
CP000359_0128 1/1 112 168 .. 1 78 [. 50.1 4.2e-14
CP000359_0087 1/1 141 204 .. 1 87 [] 49.0 8.6e-14
CP000359_2086 2/2 918 986 .. 1 87 [] 47.4 2.4e-13
CP000359_2169 1/1 489 557 .. 1 87 [] 46.5 4.4e-13
CP000359_2138 1/1 540 608 .. 1 87 [] 45.5 8.3e-13
CP000359_2204 1/1 250 316 .. 1 87 [] 31.0 1.1e-08
CP000359_1616 1/1 122 188 .. 1 87 [] 29.8 2.4e-08
CP000359_1549 1/1 194 245 .. 1 73 [. 27.3 1.2e-07

Alignments of top-scoring domains:
CP000359_2305: domain 1 of 1, from 293 to 359: score 87.5, E = 1.1e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f++++sHELRTP+taI+g+a+ Ll+ +t+ +e q
CP000359_2 293 AQRRFTSDASHELRTPVTAISGHASYLLR--------RTDPTEGQ-- 329

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re l++i+re+erl +Li lL+l+r ++g
CP000359_2 330 ----------RESLNIIRRESERLTNLIASLLQLARSDSG 359

CP000359_2086: domain 1 of 2, from 350 to 418: score 78.5, E = 3.7e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ f+an+sHELRTPLt ++g +e Ll+ + ++l++ q
CP000359_2 350 AKTAFFANASHELRTPLTLMLGPLEDLLT------GDAGPLTARQ-- 388

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e le ++r + rllrL+n lLd+sr+eag
CP000359_2 389 ----------QEVLEMAHRGSLRLLRLVNTLLDFSRLEAG 418

CP000359_1262: domain 1 of 1, from 718 to 786: score 68.0, E = 3.5e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f ++sH+LRTPL I g+ +lL++++ ++l+++
CP000359_1 718 ELEAFSYSVSHDLRTPLRHIVGFGDLLRKDAA------GHLTPKG-- 756

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+++ ++aer+++Li+dlL++sr++ +
CP000359_1 757 ----------ERYLSVMTDAAERMSQLIDDLLEFSRMGRQ 786

CP000359_1261: domain 1 of 1, from 189 to 251: score 55.6, E = 1.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ fla sHELRTPLta++gy+ +++ + ++++
CP000359_1 189 LQKTFLAETSHELRTPLTALLGYLRRAER---------EVGGSQT-- 224

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+ ++r ae + rL+ndlL+lsr e
CP000359_1 225 -------------LQDAQRVAENMTRLVNDLLQLSRGELV 251

CP000359_1512: domain 1 of 1, from 207 to 271: score 53.6, E = 4.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++ +a+++HELRTP++ +++ +++L+++++ +l++ q
CP000359_1 207 ERQQAVADIAHELRTPIAIMQARLDALEDGVY-------PLDAGQ-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++ l rL+ dl++l+ ++ag
CP000359_1 245 -------------IALLSAQTQLLTRLVGDLRTLTLADAG 271

CP000359_0906: domain 1 of 1, from 152 to 218: score 52.5, E = 9.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ +l H+L++P++a++g++e+ +e d+ +++
CP000359_0 152 VRDQLVHMLVHDLKNPIAAVMGLLEVVEE--------DHRVPDDL-- 188

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++++++++e+++ll+L ++Ld +i+ag
CP000359_0 189 ----------RDLIKVAHDETQHLLHLAVNMLDVRKIQAG 218

CP000359_0128: domain 1 of 1, from 112 to 168: score 50.1, E = 4.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e +a lsHE+RTP+t++rg +e+L+ +++++ +
CP000359_0 112 ELREATAVLSHEFRTPVTGLRGVLEALEY----------DMPPDLA- 147

peLRledpeyreyletilreaerllrLindl<-*
+ +++ l+e+erl rL++dl
CP000359_0 148 ----------QNFVRQGLQEVERLARLVEDL 168

CP000359_0087: domain 1 of 1, from 141 to 204: score 49.0, E = 8.6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++ n+ HELRTPL+a+rgy+e+L +++
CP000359_0 141 DRVALIGNVGHELRTPLAALRGYLEALTDGV-----------MVP-- 174

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ++re++ ++rL +dl srieag
CP000359_0 175 ----------SQAAPALRREVRAIERLASDLSLVSRIEAG 204

CP000359_2086: domain 2 of 2, from 918 to 986: score 47.4, E = 2.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L P+ ++ +a lL +++ ++ +e
CP000359_2 918 ELERFAYIASHDLQEPIRTVGSFAGLLARRY-------GDVLDERG- 956

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+yl+t++ a r+ L++dlL +sr+ a
CP000359_2 957 ----------RQYLHTVELGALRMKTLVDDLLVFSRLNAA 986

CP000359_2169: domain 1 of 1, from 489 to 557: score 46.5, E = 4.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L P+ a+ +a l +++ + l+e
CP000359_2 489 ELEQFAYVASHDLQAPIRAVTSFAGLVSRKYA------AQLDERG-- 527

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ yl+ i + +e++ rL++dlL +sr+ ++
CP000359_2 528 ----------QAYLRQIVENGEHMKRLVDDLLAFSRLHTQ 557

CP000359_2138: domain 1 of 1, from 540 to 608: score 45.5, E = 8.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL ++ yaelL +++ + l++
CP000359_2 540 ELEQFAYVASHDLQEPLRTVGSYAELLARRYQ------GQLDPRA-- 578

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl +++++er+++Li+dlL ++r +
CP000359_2 579 ----------DQYLAFMQDAVERMRSLIQDLLGFARVGRM 608

CP000359_2204: domain 1 of 1, from 250 to 316: score 31.0, E = 1.1e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++fl++++H+LR PL+a+ + +++ l+ ++ +e
CP000359_2 250 RQQDFLRAAAHDLRSPLAALTARVDATLA---------RDRAPER-- 285

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr l+ i ++ rl++L n lL l+r a
CP000359_2 286 ---------YRAELREIGTDLTRLSSLANHLLLLARDPAA 316

CP000359_1616: domain 1 of 1, from 122 to 188: score 29.8, E = 2.4e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f+a+l H+L+TPL a +a +L e ++l++ r
CP000359_1 122 RRSAFMATLVHDLKTPLIATGHLARVLSE---------QTLPDAAR- 158

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + +lre rll+L+ ++ d r e +
CP000359_1 159 ----------QEVGRELLRENARLLALVAQMADAHRFERE 188

CP000359_1549: domain 1 of 1, from 194 to 245: score 27.3, E = 1.2e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e l+ +sHELR PL a++++++lL+ + ++eqr
CP000359_1 194 RQREALSLASHELRRPLQALLFASDLLRQ----------ADTPEQR- 229

peLRledpeyreyletilreaerllr<-*
+ +l+ i++++ +l +
CP000359_1 230 ----------EHLLSLIEDSTAQLAS 245


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-14 3 0|=
-13 14 1|*=
-12 78 53|======*===
-11 213 276|=========================== *
-10 388 513|================================================= *
-9 444 530|======================================================== *
-8 409 397|=================================================*==
-7 327 250|===============================*=========
-6 176 143|=================*====
-5 110 78|=========*====
-4 66 42|=====*===
-3 32 22|==*=
-2 25 11|=*==
-1 15 6|*=
0 8 3|*
1 3 1|*
2 8 0|=
3 0 0|
4 1 0|=
5 0 0|
> 6 15 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 159.4229
P(chi-square) = 1.756e-28

Total sequences searched: 2335

Whole sequence top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: