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3 accessions found for Burkholderia cenocepacia AU 1054  

Data for CP000378  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000378.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000378_0819 CDS_892054-893373 93.4 2.9e-26 1
CP000378_1365 CDS_1512915-1510609 73.8 1e-20 1
CP000378_1494 CDS_1671830-1670370 72.4 2.5e-20 1
CP000378_1661 CDS_1855766-1852923 70.0 1.2e-19 1
CP000378_2028 CDS_2255710-2257263 67.3 7.3e-19 1
CP000378_1549 CDS_1736666-1735152 65.1 3.1e-18 1
CP000378_1992 CDS_2215892-2214546 59.8 9.9e-17 1
CP000378_2961 CDS_3289264-3290748 55.9 1.3e-15 1
CP000378_1775 CDS_1977809-1976544 53.1 7.7e-15 1
CP000378_1381 CDS_1529950-1531530 52.0 1.5e-14 1
CP000378_0039 CDS_35447-36814 49.7 7.2e-14 1
CP000378_0863 CDS_946623-945214 49.6 7.6e-14 1
CP000378_2490 CDS_2754645-2752231 38.6 9.5e-11 1
CP000378_2243 CDS_2490409-2488400 34.4 1.5e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000378_0819 1/1 206 272 .. 1 87 [] 93.4 2.9e-26
CP000378_1365 1/1 393 458 .. 1 87 [] 73.8 1e-20
CP000378_1494 1/1 262 328 .. 1 87 [] 72.4 2.5e-20
CP000378_1661 1/1 678 756 .. 1 87 [] 70.0 1.2e-19
CP000378_2028 1/1 283 348 .. 1 87 [] 67.3 7.3e-19
CP000378_1549 1/1 273 341 .. 1 87 [] 65.1 3.1e-18
CP000378_1992 1/1 213 278 .. 1 87 [] 59.8 9.9e-17
CP000378_2961 1/1 240 305 .. 1 87 [] 55.9 1.3e-15
CP000378_1775 1/1 220 278 .. 1 87 [] 53.1 7.7e-15
CP000378_1381 1/1 154 220 .. 1 87 [] 52.0 1.5e-14
CP000378_0039 1/1 235 301 .. 1 87 [] 49.7 7.2e-14
CP000378_0863 1/1 207 269 .. 1 87 [] 49.6 7.6e-14
CP000378_2490 1/1 541 613 .. 1 87 [] 38.6 9.5e-11
CP000378_2243 1/1 420 482 .. 1 81 [. 34.4 1.5e-09

Alignments of top-scoring domains:
CP000378_0819: domain 1 of 1, from 206 to 272: score 93.4, E = 2.9e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt+++g++e+++e +l+ee+r
CP000378_0 206 MRRDFVANVSHELKTPLTVLSGFLETMRE---------LPLNEEDR- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ ++++a r+++++ dlL l+++e +
CP000378_0 243 ----------ARYLDMMEQQASRMRHIVTDLLVLAKLEGE 272

CP000378_1365: domain 1 of 1, from 393 to 458: score 73.8, E = 1e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+e+la++sHELRTPL++I g +e+L++ t + q
CP000378_1 393 LKDELLATVSHELRTPLNVIYGWIEVLRN---------TGDHALQ-- 428

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i+r+a++l r++ d+Ld s + +g
CP000378_1 429 ----------HQAIDAIDRSARSLTRMVGDILDASSLATG 458

CP000378_1494: domain 1 of 1, from 262 to 328: score 72.4, E = 2.5e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s+f a+l+H+LRTPL+ +rg++e++l+ ++s ++
CP000378_1 262 HLSQFSADLAHDLRTPLNNMRGATEVALA---------RPRSVDE-- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ +le+ l+e +rl r+i+++L l+r+e++
CP000378_1 298 ---------YQTLLESNLEEYDRLARMIENVLFLARAEHP 328

CP000378_1661: domain 1 of 1, from 678 to 756: score 70.0, E = 1.2e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPLt+I g++++L + g++++ + +++
CP000378_1 678 LRNSLLSAISHDLRTPLTTIVGFSSMLAN-------GRAAAQAGDAA 717

peLR....ledpeyreyletilreaerllrLindlLdlsrieag<-*
++R +++ e+++ i++ea r+ ++ +lLd++r++ag
CP000378_1 718 AAARlaqrE-----GELVDAIHDEALRMTGIVTNLLDMARLQAG 756

CP000378_2028: domain 1 of 1, from 283 to 348: score 67.3, E = 7.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ae +l+ ++ +++
CP000378_2 283 LQKRFIADAAHQMKTPLAGLRTQAEFALR---------HPVPPDV-- 318

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ le i ++e+ rL+ +lL l+r+e+
CP000378_2 319 ----------QRSLEQIATSSEQAARLVTQLLALARAENR 348

CP000378_1549: domain 1 of 1, from 273 to 341: score 65.1, E = 3.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++ n+sH+LRTPLt++ gy+e+L ++ ++l e++r
CP000378_1 273 QRRELITNISHDLRTPLTSLHGYLETLSLKA-------DTLAEPER- 311

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+yl+++l ++ rL + l +l+r+e+g
CP000378_1 312 ----------RRYLSIALAQSAKVGRLAQALFELARLESG 341

CP000378_1992: domain 1 of 1, from 213 to 278: score 59.8, E = 9.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+a++ a+l + ++ ++
CP000378_1 213 TQKAFVADAAHELRTPLAAVQIQAQLVAR---------AKDDASR-- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re++ +++ + r rL ++lL l+r+e
CP000378_1 249 ----------REAIADLQDGVSRATRLTEQLLALARAEPD 278

CP000378_2961: domain 1 of 1, from 240 to 305: score 55.9, E = 1.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLta++++ae + ++++ q+
CP000378_2 240 AQRKFIADAAHQLRTPLTAVKLHAEQAAV----------ARDPHQT- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++ +a+r rL n+lL l+r+e g
CP000378_2 276 ----------FAAVRELRAAADRAVRLSNQLLSLARAEPG 305

CP000378_1775: domain 1 of 1, from 220 to 278: score 53.1, E = 7.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+LRTPL+ +r+ ae++ +
CP000378_1 220 DRAVMLAGVAHDLRTPLARMRLRAEMMDD------------------ 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + + r++++++++++++L ++ +a
CP000378_1 249 ----------ARLRDGVVRDVDSMSHIVDQFLVFAHGGAD 278

CP000378_1381: domain 1 of 1, from 154 to 220: score 52.0, E = 1.5e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f+a+l+HELR+ L+ +r + +L+ + +++ +
CP000378_1 154 RLSVFIAMLAHELRNHLAPLRNSVGVLQS---------LPDPAPVL- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + + r++ +l rL++dlLd ri ag
CP000378_1 191 ----------AQCRDAVNRQVAQLTRLVDDLLDVGRITAG 220

CP000378_0039: domain 1 of 1, from 235 to 301: score 49.7, E = 7.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++H+LRTP++++ + ++ ++ +++ + e
CP000378_0 235 TQRRFIADAAHQLRTPIAVLDTQIQYAQQ--------RGNGDHEL-- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l++++r+++ + + + lL l+ +ea
CP000378_0 272 ----------ASVLDSMQRSSRKMADVTDKLLLLAHAEAT 301

CP000378_0863: domain 1 of 1, from 207 to 269: score 49.6, E = 7.6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++ ++sHEL+TPL+ + + + lL + ++++
CP000378_0 207 QQREMMHGISHELKTPLARLEFGLALLAD-------------ADET- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + ++r+++ l++L+ +lL++ r+e+g
CP000378_0 240 ----------GRMRDALRRDVRELDELVTELLTIGRLEQG 269

CP000378_2490: domain 1 of 1, from 541 to 613: score 38.6, E = 9.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l +++l +++ +
CP000378_2 541 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL------SDKLAPPD-A 580

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ L ++ i +++ + r+++d+++++r
CP000378_2 581 DVL-------KRGATMIVNQVAAMKRMVDDFREYARTPPA 613

CP000378_2243: domain 1 of 1, from 420 to 482: score 34.4, E = 1.5e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+a+r +++ + +++e+ ++
CP000378_2 420 ALGQMAAGITHELNQPLAALRSFSDNTRV--------LLDRGEQAAA 458

peLRledpeyreyletilreaerllrLindlLdl<-*
re le i +er+ ++ n+l +
CP000378_2 459 ----------RENLEAIAALTERMGKITNQLKLF 482


Histogram of all scores:
score obs exp (one = represents 11 sequences)
----- --- ---
-14 4 0|=
-13 37 2|*===
-12 114 67|======*====
-11 260 351|======================== *
-10 484 652|============================================ *
-9 614 673|======================================================== *
-8 514 504|=============================================*=
-7 371 317|============================*=====
-6 245 182|================*======
-5 152 100|=========*====
-4 66 53|====*=
-3 42 28|==*=
-2 28 14|=*=
-1 11 7|*
0 3 4|*
1 3 2|*
2 0 1|*
3 0 0|
> 4 17 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 183.0887
P(chi-square) = 2.36e-33

Total sequences searched: 2965

Whole sequence top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: