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Thermotogae
Classification of phyla is from NCBI page
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76 projects found  

3 accessions found for Burkholderia cenocepacia AU 1054  

Data for CP000380  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000380.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000380_0441 CDS_502036-503178 61.1 1.5e-17 1
CP000380_0138 CDS_153124-155466 55.9 4.4e-16 1
CP000380_0113 CDS_116474-115197 43.2 1.8e-12 1
CP000380_1007 CDS_1141175-1139904 43.1 1.8e-12 1
CP000380_0451 CDS_517920-515404 42.8 2.2e-12 1
CP000380_0651 CDS_736644-735283 40.2 1.2e-11 1
CP000380_0090 CDS_96097-94262 34.7 4.4e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000380_0441 1/1 152 220 .. 1 87 [] 61.1 1.5e-17
CP000380_0138 1/1 446 510 .. 1 87 [] 55.9 4.4e-16
CP000380_0113 1/1 212 270 .. 1 87 [] 43.2 1.8e-12
CP000380_1007 1/1 202 266 .. 1 87 [] 43.1 1.8e-12
CP000380_0451 1/1 588 658 .. 1 87 [] 42.8 2.2e-12
CP000380_0651 1/1 234 293 .. 1 87 [] 40.2 1.2e-11
CP000380_0090 1/1 348 449 .. 1 87 [] 34.7 4.4e-10

Alignments of top-scoring domains:
CP000380_0441: domain 1 of 1, from 152 to 220: score 61.1, E = 1.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++nl+HE+++PL +Irg+a+lL+ el +e+ ++
CP000380_0 152 VNKQLIRNLAHEIKNPLGGIRGAAQLLEFEL-------GERERGEL- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey+++i++e++rl+ L+++lL+ r +
CP000380_0 191 ----------REYTQVIIKESDRLQTLVDRLLEPHRHPHI 220

CP000380_0138: domain 1 of 1, from 446 to 510: score 55.9, E = 4.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k e l ++sH+LR PL++I gya+lLle ++ q
CP000380_0 446 QKIETLGYVSHDLRAPLSTINGYAKLLLE----------GATRGQ-- 480

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++i+r++++ l+Li++lL ++++e +
CP000380_0 481 ----------ARLIRSIDRSIRYQLALIDELLAFTKAELQ 510

CP000380_0113: domain 1 of 1, from 212 to 270: score 43.2, E = 1.8e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+++H+LRTP+t ++ a+lL +
CP000380_0 212 ERAVMLASIAHDLRTPITRMQVRADLLTD------------------ 240

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r e lr++e+++r i ++Ld++r +
CP000380_0 241 ----------RGDREGFLRDTESMSRVITQFLDFAREIPE 270

CP000380_1007: domain 1 of 1, from 202 to 266: score 43.1, E = 1.8e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a ++HE+R+P+ a+r+ ae +l+ + q
CP000380_1 202 MLGKLAAQVAHEIRNPMGAMRLKAENALA----------GDGRRQ-- 236

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l++il ++er++++++ lL l++ +
CP000380_1 237 ----------QDALRVILAQIERIDAQLSSLLALTQPVRP 266

CP000380_0451: domain 1 of 1, from 588 to 658: score 42.8, E = 2.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL++PL+aI y++ l+ l +++ ++e++
CP000380_0 588 TMGEMASSIAHELNQPLAAINNYCSGTLA-----LVKSGRGTPETL- 628

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le+ ++a r ++ +++++ + ++
CP000380_0 629 ----------QPALEKTAQQALRAGMIVKRIREFVKRSEP 658

CP000380_0651: domain 1 of 1, from 234 to 293: score 40.2, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ +
CP000380_0 234 DRALMLAGISHDLRTPLARLRLETEMSPSD----------------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + +++e+++r+i + d++r +
CP000380_0 264 ----------QATKDAMVDDIEQMDRIIAAFIDYARPSQR 293

CP000380_0090: domain 1 of 1, from 348 to 449: score 34.7, E = 4.4e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldk....v.lagdtels
+ ++++a+++HE+++P+ +++++ +L++++ ++ +v +a++++l+
CP000380_0 348 SIGQLAAGVAHEINNPIGFVSANLNTLKTWV-RslldVvAAHEAALP 393

eeqrlpeLR..l..........edp.eyreyletilreaerllrLindlL
+ p+ R+ l+ ++ + + +++e++ +++ ++ a r +r+++dl+
CP000380_0 394 QLD--PATRdaLtavhravdldYVRdEIAMLIDESIDGALRVRRIVQDLR 441

dlsrieag<-*
d+sr +
CP000380_0 442 DFSRPASD 449


Histogram of all scores:
score obs exp (one = represents 4 sequences)
----- --- ---
-14 1 0|=
-13 6 0|==
-12 39 23|=====*====
-11 87 123|====================== *
-10 161 228|========================================= *
-9 203 236|=================================================== *
-8 214 176|===========================================*==========
-7 149 111|===========================*==========
-6 82 64|===============*=====
-5 47 35|========*===
-4 17 18|====*
-3 7 9|==*
-2 8 5|=*
-1 4 2|*
0 2 1|*
1 3 0|=
> 2 10 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 77.0904
P(chi-square) = 1.862e-12

Total sequences searched: 1040

Whole sequence top hits:
tophits_s report:
Total hits: 7
Satisfying E cutoff: 7
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 7
Satisfying E cutoff: 7
Total memory: 23K


Acknowledgements:

This research is funded by:

Developed by: