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Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
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Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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76 projects found  

1 accessions found for Neisseria meningitidis 053442  

Data for CP000381  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000381.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000381_0409 CDS_451516-452736 51.6 1.4e-14 1
CP000381_1444 CDS_1537578-1539095 44.9 1.1e-12 1
CP000381_0509 CDS_566281-564875 44.8 1.2e-12 1
CP000381_1936 CDS_2079907-2077787 36.9 2e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000381_0409 1/1 183 248 .. 1 87 [] 51.6 1.4e-14
CP000381_1444 1/1 312 381 .. 1 87 [] 44.9 1.1e-12
CP000381_0509 1/1 236 299 .. 1 87 [] 44.8 1.2e-12
CP000381_1936 1/1 483 555 .. 1 87 [] 36.9 2e-10

Alignments of top-scoring domains:
CP000381_0409: domain 1 of 1, from 183 to 248: score 51.6, E = 1.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++HELRTP+ta+++ ae L + l+++
CP000381_0 183 HRQRFVADAAHELRTPMTALSLQAERLNN---------MSLPPDA-- 218

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +++++++r +L+++lL l+r ++
CP000381_0 219 ----------ARQPAVLQQSIRRNKHLLEQLLALARSQSD 248

CP000381_1444: domain 1 of 1, from 312 to 381: score 44.9, E = 1.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++anl+HE+R+P++aIr + +lL+e+++ +++++
CP000381_1 312 ALGQLTANLAHEIRNPMSAIRHANDLLRENME-----AGAADPFN-- 351

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++i+ + r++++++d+ l +
CP000381_1 352 ----------AKLCKIIDGNVCRIDKMLEDISSLNKRNKT 381

CP000381_0509: domain 1 of 1, from 236 to 299: score 44.8, E = 1.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +l ++sHE+R PL+ +++ + l+++ ++ +q
CP000381_0 236 KERHLLHHVSHEMRSPLARMQAIVGLIQA-----------QPQKQ-- 269

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl++++ e+ r++ L +lL+lsr+e+
CP000381_0 270 ----------EQYLKRLEGELTRMDTLAGELLTLSRLETS 299

CP000381_1936: domain 1 of 1, from 483 to 555: score 36.9, E = 2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e + l+HE+R+PLt I++ ae L +l ++l+e++++
CP000381_1 483 AWGEVAKRLAHEIRNPLTPIQLSAERLAWKLG------GKLDEQDAQ 523

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ti +++ l ++++ ++ ++r +
CP000381_1 524 IL--------TRSTDTIVKQVAALKEMVEAFRNYARSPSL 555


Histogram of all scores:
score obs exp (one = represents 7 sequences)
----- --- ---
-15 3 0|=
-14 12 0|==
-13 64 1|*=========
-12 129 46|======*============
-11 258 239|==================================*==
-10 349 444|================================================== *
-9 402 458|==========================================================*
-8 301 343|=========================================== *
-7 207 216|==============================*
-6 125 124|=================*
-5 63 68|=========*
-4 44 36|=====*=
-3 31 19|==*==
-2 11 10|=*
-1 7 5|*
0 4 2|*
1 3 1|*
2 1 0|=
> 3 6 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 192.7451
P(chi-square) = 2.374e-35

Total sequences searched: 2020

Whole sequence top hits:
tophits_s report:
Total hits: 4
Satisfying E cutoff: 4
Total memory: 20K

Domain top hits:
tophits_s report:
Total hits: 4
Satisfying E cutoff: 4
Total memory: 22K


Acknowledgements:

This research is funded by:

Developed by: