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Classification of phyla is from NCBI page
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106 projects found  

2 accessions found for Mycobacterium sp. MCS  

Data for CP000384  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000384.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000384_3908 CDS_4182966-4181368 86.3 5.5e-24 1
CP000384_0659 CDS_721179-722357 74.1 1.6e-20 1
CP000384_0349 CDS_388781-392953 73.9 1.8e-20 1
CP000384_4571 CDS_4865305-4863884 71.7 7.2e-20 1
CP000384_1338 CDS_1458149-1459816 71.3 9.6e-20 1
CP000384_0707 CDS_760884-759850 67.8 9.6e-19 1
CP000384_4212 CDS_4489338-4491848 62.8 2.4e-17 1
CP000384_4283 CDS_4568811-4567264 60.5 1.1e-16 1
CP000384_2980 CDS_3163321-3164676 53.5 1.1e-14 1
CP000384_2674 CDS_2841614-2843197 50.3 8.5e-14 1
CP000384_4431 CDS_4732403-4733749 48.8 2.3e-13 1
CP000384_0165 CDS_181082-182419 46.1 1.3e-12 1
CP000384_2891 CDS_3066027-3067166 45.1 2.6e-12 1
CP000384_1428 CDS_1566082-1564898 44.3 4.2e-12 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000384_3908 1/1 300 367 .. 1 87 [] 86.3 5.5e-24
CP000384_0659 1/1 158 224 .. 1 87 [] 74.1 1.6e-20
CP000384_0349 1/1 351 417 .. 1 87 [] 73.9 1.8e-20
CP000384_4571 1/1 245 309 .. 1 87 [] 71.7 7.2e-20
CP000384_1338 1/1 297 364 .. 1 87 [] 71.3 9.6e-20
CP000384_0707 1/1 112 178 .. 1 87 [] 67.8 9.6e-19
CP000384_4212 1/1 607 675 .. 1 87 [] 62.8 2.4e-17
CP000384_4283 1/1 240 312 .. 1 87 [] 60.5 1.1e-16
CP000384_2980 1/1 235 301 .. 1 87 [] 53.5 1.1e-14
CP000384_2674 1/1 288 356 .. 1 87 [] 50.3 8.5e-14
CP000384_4431 1/1 231 297 .. 1 87 [] 48.8 2.3e-13
CP000384_0165 1/1 221 287 .. 1 87 [] 46.1 1.3e-12
CP000384_2891 1/1 141 205 .. 1 87 [] 45.1 2.6e-12
CP000384_1428 1/1 156 220 .. 1 87 [] 44.3 4.2e-12

Alignments of top-scoring domains:
CP000384_3908: domain 1 of 1, from 300 to 367: score 86.3, E = 5.5e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+aIrgy+el+++ ++++l+ +
CP000384_3 300 RVRQFVADASHELRTPLAAIRGYTELAQR-------HSDALPGDV-- 337

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++++e+ r+ rL++d+L l+r++ g
CP000384_3 338 ----------AHAMNRVESETARMTRLVEDMLLLARLDDG 367

CP000384_0659: domain 1 of 1, from 158 to 224: score 74.1, E = 1.6e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a+ ++ae+Ll+ ++ ++e++
CP000384_0 158 TRRDFVANVSHELKTPVGAMGLLAEALLA---------SADDPETV- 194

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ ++ +ea+rl ++i +l +lsr++ g
CP000384_0 195 ----------RRFAGKMVDEAHRLADMIGELIELSRLQGG 224

CP000384_0349: domain 1 of 1, from 351 to 417: score 73.9, E = 1.8e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ f++n+sHE+RTPLt I+g + +l+ +el+
CP000384_0 351 AKTTFFSNISHEFRTPLTLILGPLAEMLR--------TSELDVRV-- 387

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re le ++r + rl +L+n lLd+sri+ag
CP000384_0 388 ----------REELELAHRNGLRLAKLVNTLLDFSRIQAG 417

CP000384_4571: domain 1 of 1, from 245 to 309: score 71.7, E = 7.2e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ +++ e +
CP000384_4 245 RMRRFITDASHELRTPLTTIRGFAELYRQGA--------ARDVEML- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++i++e++r+ L++dlL l+r++a+
CP000384_4 283 -------------MNRIESESRRMGLLVEDLLLLARLDAQ 309

CP000384_1338: domain 1 of 1, from 297 to 364: score 71.3, E = 9.6e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++++l++
CP000384_1 297 LQRRFTSDVSHELRTPLTTVRMAADLIHD-------HSDDLDPAL-- 334

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e + +e++r + L++dlL++sr +ag
CP000384_1 335 ----------RRSTELMVSELDRFETLLSDLLEISRHDAG 364

CP000384_0707: domain 1 of 1, from 112 to 178: score 67.8, E = 9.6e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a +sH+LRTPL++Ir+ +e++ + + + +++
CP000384_0 112 SRRQLVAFVSHDLRTPLAGIRAVSEAIAD---------GLVGGDEV- 148

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + i++e+ rl+++++dl ++s+i ag
CP000384_0 149 ----------RAHAKHIEQESIRLSEMVDDLFEMSKINAG 178

CP000384_4212: domain 1 of 1, from 607 to 675: score 62.8, E = 2.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPL+a +++++ L+ + + s+++r
CP000384_4 607 LRRSLLSAVSHDLRTPLAAAKAAVSSLRS-------DEVDFSADDR- 645

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l t+++++++l +L+ +lLd sr+ ag
CP000384_4 646 ----------AELLATVEESVDQLTALVANLLDSSRLAAG 675

CP000384_4283: domain 1 of 1, from 240 to 312: score 60.5, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++++++ HELRTPLt++r+++elL + + ++g + l+ee++
CP000384_4 240 RQARLVSDAGHELRTPLTSLRTNVELLMASQ---APGAPRLPEEEM- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ ++e l+ L+ dl dl+r eag
CP000384_4 283 ----------AGLRADVIAQIEELSTLVGDLVDLTRDEAG 312

CP000384_2980: domain 1 of 1, from 235 to 301: score 53.5, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a +sHELRTPLta+r+++e+L + ++++eqr
CP000384_2 235 SARDFAAVASHELRTPLTAMRTNLEVLST---------LDMTDEQR- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ + r r+++ + l l++ e
CP000384_2 272 ----------KEVINDVVRTQTRIEATLTALERLAQGELT 301

CP000384_2674: domain 1 of 1, from 288 to 356: score 50.3, E = 8.5e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL + +++lL++++ +++ +e
CP000384_2 288 ELEQFAYVASHDLQEPLRKVASFCQLLEKRY-------GDKLDERG- 326

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey++ + + a+r++ LindlL++sr +
CP000384_2 327 ----------VEYIKYAVDGAKRMQVLINDLLTFSRVGRL 356

CP000384_4431: domain 1 of 1, from 231 to 297: score 48.8, E = 2.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f++ +HELRTPLta+r+++e+L + +l +eqr
CP000384_4 231 SARDFASVSAHELRTPLTAMRTNLEVLAT---------LDLADEQR- 267

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ ++r r+++ ++ l l++ e
CP000384_4 268 ----------KEVINDVIRTQSRIEATLSALERLAQGELS 297

CP000384_0165: domain 1 of 1, from 221 to 287: score 46.1, E = 1.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+an++HELRTPLta+r+ +++L+ ++l+e++r
CP000384_0 221 AAQDFAANAAHELRTPLTAMRADLDTLRI---------HDLPEDER- 257

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + + r+ +r +++i l +l+ +
CP000384_0 258 ----------AEVVADLSRAQRRVEAIITALGQLASGQLA 287

CP000384_2891: domain 1 of 1, from 141 to 205: score 45.1, E = 2.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++++l+HE+RTPL+++ +y e++++++ l++e+
CP000384_2 141 TRRRLFSDLAHEIRTPLAVLEAYFEAIEDGV-------RSLTPET-- 178

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ rl r dl l+r+e+
CP000384_2 179 -------------AAMLRDQTGRLVRFAGDLGALARAEES 205

CP000384_1428: domain 1 of 1, from 156 to 220: score 44.3, E = 4.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ +l+HE+RTP++++ +y+e+L++++ +l++++
CP000384_1 156 TRQQLFGDLAHEIRTPVAVLDAYIEALEDGV-------RTLTPQT-- 193

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++rl r d+ l+r+e+
CP000384_1 194 -------------AAMLRDQTRRLVRFSGDVAALARAEES 220


Histogram of all scores:
score obs exp (one = represents 19 sequences)
----- --- ---
-15 2 0|=
-14 11 0|=
-13 56 4|*==
-12 207 123|======*====
-11 502 639|=========================== *
-10 917 1185|================================================= *
-9 1109 1224|==========================================================*
-8 967 916|================================================*==
-7 680 577|==============================*=====
-6 385 332|=================*===
-5 241 182|=========*===
-4 143 97|=====*==
-3 55 51|==*
-2 46 27|=*=
-1 27 14|*=
0 11 7|*
1 6 3|*
2 5 2|*
3 3 1|*
4 1 0|=
> 5 17 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 254.1918
P(chi-square) = 0

Total sequences searched: 5391

Whole sequence top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: