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4 accessions found for Burkholderia ambifaria AMMD  

Data for CP000440  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000440.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000440_1593 CDS_1768676-1770793 98.4 1.2e-27 1
CP000440_1180 CDS_1293823-1295142 93.6 2.8e-26 1
CP000440_2829 CDS_3127698-3125272 67.6 6.3e-19 1
CP000440_2696 CDS_2974887-2976440 67.3 7.9e-19 1
CP000440_2318 CDS_2560976-2558139 66.5 1.3e-18 1
CP000440_2180 CDS_2406246-2405104 61.2 4.3e-17 1
CP000440_2659 CDS_2935431-2934094 58.8 2e-16 1
CP000440_0065 CDS_76660-75176 58.7 2.1e-16 1
CP000440_2440 CDS_2694220-2692904 54.1 4.4e-15 1
CP000440_0023 CDS_36804-35437 51.1 3.1e-14 1
CP000440_1232 CDS_1350436-1349066 47.8 2.5e-13 1
CP000440_2170 CDS_2390336-2392852 42.8 6.9e-12 1
CP000440_2118 CDS_2334542-2333421 41.8 1.3e-11 1
CP000440_1922 CDS_2122178-2123539 40.2 3.6e-11 1
CP000440_3171 CDS_3512633-3510219 38.6 1e-10 1
CP000440_2922 CDS_3228111-3226093 34.4 1.7e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000440_1593 1/1 26 91 .. 1 87 [] 98.4 1.2e-27
CP000440_1180 1/1 206 272 .. 1 87 [] 93.6 2.8e-26
CP000440_2829 1/1 322 386 .. 1 87 [] 67.6 6.3e-19
CP000440_2696 1/1 281 346 .. 1 87 [] 67.3 7.9e-19
CP000440_2318 1/1 678 754 .. 1 87 [] 66.5 1.3e-18
CP000440_2180 1/1 152 220 .. 1 87 [] 61.2 4.3e-17
CP000440_2659 1/1 213 278 .. 1 87 [] 58.8 2e-16
CP000440_0065 1/1 240 305 .. 1 87 [] 58.7 2.1e-16
CP000440_2440 1/1 220 278 .. 1 87 [] 54.1 4.4e-15
CP000440_0023 1/1 235 301 .. 1 87 [] 51.1 3.1e-14
CP000440_1232 1/1 207 272 .. 1 87 [] 47.8 2.5e-13
CP000440_2170 1/1 588 658 .. 1 87 [] 42.8 6.9e-12
CP000440_2118 1/1 151 216 .. 1 87 [] 41.8 1.3e-11
CP000440_1922 1/1 234 293 .. 1 87 [] 40.2 3.6e-11
CP000440_3171 1/1 541 613 .. 1 87 [] 38.6 1e-10
CP000440_2922 1/1 423 485 .. 1 81 [. 34.4 1.7e-09

Alignments of top-scoring domains:
CP000440_1593: domain 1 of 1, from 26 to 91: score 98.4, E = 1.2e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla +sHE+RTP+++++g++elL++ t l+++q
CP000440_1 26 AKSDFLARMSHEIRTPMNGVLGMTELLQR---------TRLTSKQ-- 61

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++++t++r+++ ll +i+d+Ld+s+ieag
CP000440_1 62 ----------RKFVDTVYRSGQTLLVIIDDILDFSKIEAG 91

CP000440_1180: domain 1 of 1, from 206 to 272: score 93.6, E = 2.8e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt+++g++e+++e +l+ee+r
CP000440_1 206 MRRDFVANVSHELKTPLTVLSGFLETMRE---------LPLNEEDR- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle ++++a r+++++ dlL l+++e +
CP000440_1 243 ----------ARYLEMMEQQASRMRHIVTDLLVLAKLEGE 272

CP000440_2829: domain 1 of 1, from 322 to 386: score 67.6, E = 6.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +fla lsHE+RTPL+a++g +elL+ + s eq
CP000440_2 322 NRLRFLAVLSHEIRTPLNALIGSVELLRQ----------TTSREQ-- 356

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+++ ++e l++L+nd+L l+riea+
CP000440_2 357 ----------ADLLHIAGTASEALSALLNDILALARIEAN 386

CP000440_2696: domain 1 of 1, from 281 to 346: score 67.3, E = 7.9e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ae +l+ ++ +++
CP000440_2 281 LQKRFIADAAHQMKTPLAGLRTQAEFALR---------HPVPPDV-- 316

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ le i ++e+ rL+ +lL l+r+e+
CP000440_2 317 ----------QRSLEQIATSSEQAARLVTQLLALARAENR 346

CP000440_2318: domain 1 of 1, from 678 to 754: score 66.5, E = 1.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPLt+I g++++L + + + +++++
CP000440_2 678 LRNSLLSAISHDLRTPLTTIVGFSSMLAN---------ARAAAPHTP 715

peLR....ledpeyreyletilreaerllrLindlLdlsrieag<-*
+ R+ +++ e+++ i++ea r+ ++ +lLd++r++ag
CP000440_2 716 AAERsaqrE-----GELVDAIHDEALRMMGIVTNLLDMARLQAG 754

CP000440_2180: domain 1 of 1, from 152 to 220: score 61.2, E = 4.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++nl+HE+++PL +Irg+a+lL+ else +r
CP000440_2 152 VNKQLIRNLAHEIKNPLGGIRGAAQLLEF----------ELSERER- 187

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e rey+++i++e++rl+ L+++lL+ r +
CP000440_2 188 -------GELREYTQVIIKESDRLQTLVDRLLEPHRHPHI 220

CP000440_2659: domain 1 of 1, from 213 to 278: score 58.8, E = 2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+a++ a+l + ++++ r
CP000440_2 213 TQKAFVADAAHELRTPLAAVQIQAQLVAR----------AKDDTSR- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re++ +++ + r rL ++lL l+r+e
CP000440_2 249 ----------REAIADLQDGVSRATRLTEQLLALARAEPD 278

CP000440_0065: domain 1 of 1, from 240 to 305: score 58.7, E = 2.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLta++++ae + +++++q+
CP000440_0 240 AQRKFIADAAHQLRTPLTAVKLHAEQAAV----------ARDPQQT- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++ +a+r rL n+lL l+r+e g
CP000440_0 276 ----------YAAVRELRAAADRAVRLSNQLLSLARAEPG 305

CP000440_2440: domain 1 of 1, from 220 to 278: score 54.1, E = 4.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+LRTPL+ +r+ ae++ +
CP000440_2 220 DRAVMLAGVAHDLRTPLARMRLRAEMMDD------------------ 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + + r++++++++++++L ++ +a
CP000440_2 249 ----------ARLRDGVVRDVDSMSHIVDQFLAFAHGGAD 278

CP000440_0023: domain 1 of 1, from 235 to 301: score 51.1, E = 3.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++H+LRTP++++ + ++ ++ +++ +++
CP000440_0 235 TQRRFIADAAHQLRTPIAVLDTQIQYAQQ--------RGNGDPDL-- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l++++r+++ + + + lL l+ +ea
CP000440_0 272 ----------ASVLDSMQRSSRKMADVTDKLLLLAHAEAT 301

CP000440_1232: domain 1 of 1, from 207 to 272: score 47.8, E = 2.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++ ++sHEL+TPL+ + + + lL e ++ s
CP000440_1 207 QQREMMHGISHELKTPLARLEFGLALLAE---------SDESGRM-- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re + ++r+++ l++L+ +lL++ r+e+g
CP000440_1 243 ----------RERRDELRRDVRELDELVTELLTIGRLEQG 272

CP000440_2170: domain 1 of 1, from 588 to 658: score 42.8, E = 6.9e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL++PL+aI y++ l+ l +++ ++e++
CP000440_2 588 TMGEMASSIAHELNQPLAAINNYCSGTLA-----LVKSGRGTPETL- 628

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le+ ++a r ++ +++++ + ++
CP000440_2 629 ----------QPALEKTAQQALRAGMIVKRIREFVKRSEP 658

CP000440_2118: domain 1 of 1, from 151 to 216: score 41.8, E = 1.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +l +l H++RTPL +I +a+ L + +++e
CP000440_2 151 SRNLLLGMLGHDMRTPLQTIHVTASYLAA---------LNAGEAV-- 186

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +++r++ r++ L++dl d+ r + g
CP000440_2 187 ----------SDAAARLIRSGSRMQGLLDDLCDYNRTQLG 216

CP000440_1922: domain 1 of 1, from 234 to 293: score 40.2, E = 3.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ +
CP000440_1 234 DRALMLAGISHDLRTPLARLRLETEMSPSD----------------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + +++e+++r+i + d++r +
CP000440_1 264 ----------QATKDAMVDDIEQMDRIIAAFIDYARPSQR 293

CP000440_3171: domain 1 of 1, from 541 to 613: score 38.6, E = 1e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l +++l +++ +
CP000440_3 541 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL------SDKLAPPD-A 580

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ L ++ i +++ + r+++d+++++r
CP000440_3 581 DVL-------KRGATMIVNQVAAMKRMVDDFREYARTPPA 613

CP000440_2922: domain 1 of 1, from 423 to 485: score 34.4, E = 1.7e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+a+r +++ + +++e+ ++
CP000440_2 423 ALGQMAAGITHELNQPLAALRSFSDNTRV--------LLDRGEQAAA 461

peLRledpeyreyletilreaerllrLindlLdl<-*
re le i +er+ ++ n+l +
CP000440_2 462 ----------RENLEAIAALTERMGKITNQLKLF 485


Histogram of all scores:
score obs exp (one = represents 11 sequences)
----- --- ---
-14 7 0|=
-13 33 2|*==
-12 130 73|======*=====
-11 298 380|============================ *
-10 533 706|================================================= *
-9 603 729|======================================================= *
-8 571 546|=================================================*==
-7 439 344|===============================*========
-6 263 198|=================*======
-5 152 108|=========*====
-4 78 58|=====*==
-3 35 30|==*=
-2 24 16|=*=
-1 11 8|*
0 8 4|*
1 4 2|*
2 2 1|*
3 0 0|
> 4 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 203.8667
P(chi-square) = 1.172e-37

Total sequences searched: 3213

Whole sequence top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: