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Firmicutes Fusobacteria Gammaproteobacteria
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Thermotogae
Classification of phyla is from NCBI page
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4 accessions found for   

Data for CP000441  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000441.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000441_1928 CDS_2183660-2186668 90.8 1.3e-25 1
CP000441_1926 CDS_2179199-2182267 87.4 1.1e-24 1
CP000441_0573 CDS_661977-663971 72.5 2e-20 1
CP000441_0487 CDS_561202-559754 67.0 7e-19 1
CP000441_1960 CDS_2217447-2216032 60.5 5e-17 1
CP000441_0450 CDS_517795-519186 60.0 6.7e-17 1
CP000441_1146 CDS_1305458-1304328 58.2 2.2e-16 1
CP000441_1135 CDS_1283496-1284872 56.3 7.4e-16 1
CP000441_1920 CDS_2174322-2172511 53.0 6.4e-15 1
CP000441_1860 CDS_2111828-2110236 44.8 1.4e-12 1
CP000441_0002 CDS_2213-1434 42.9 4.7e-12 1
CP000441_1467 CDS_1676871-1678787 32.2 5e-09 1
CP000441_2097 CDS_2366701-2365280 29.7 2.6e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000441_1928 1/1 520 585 .. 1 87 [] 90.8 1.3e-25
CP000441_1926 1/1 501 566 .. 1 87 [] 87.4 1.1e-24
CP000441_0573 1/1 285 350 .. 1 87 [] 72.5 2e-20
CP000441_0487 1/1 234 301 .. 1 87 [] 67.0 7e-19
CP000441_1960 1/1 250 316 .. 1 87 [] 60.5 5e-17
CP000441_0450 1/1 240 305 .. 1 87 [] 60.0 6.7e-17
CP000441_1146 1/1 161 226 .. 1 87 [] 58.2 2.2e-16
CP000441_1135 1/1 233 298 .. 1 87 [] 56.3 7.4e-16
CP000441_1920 1/1 235 300 .. 1 87 [] 53.0 6.4e-15
CP000441_1860 1/1 157 225 .. 1 87 [] 44.8 1.4e-12
CP000441_0002 1/1 28 95 .. 1 87 [] 42.9 4.7e-12
CP000441_1467 1/1 402 470 .. 1 87 [] 32.2 5e-09
CP000441_2097 1/1 241 298 .. 1 79 [. 29.7 2.6e-08

Alignments of top-scoring domains:
CP000441_1928: domain 1 of 1, from 520 to 585: score 90.8, E = 1.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL+aI g++el+++ ++l++e+
CP000441_1 520 AKSTFLATMSHEIRTPLNAIVGNLELMER---------APLPAEE-- 555

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+t+ ++++ llr ind+Ldls+ e++
CP000441_1 556 ----------RRRLQTVMSSSDALLRVINDVLDLSKVESN 585

CP000441_1926: domain 1 of 1, from 501 to 566: score 87.4, E = 1.1e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla+ sHE+RTPL++I+g++elL++ t+l++ q
CP000441_1 501 AKSSFLAATSHEIRTPLNVILGNLELLER---------TALDASQ-- 536

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++t++ +ae ll++++d+Ld+s+ieag
CP000441_1 537 ----------QSRVQTLRASAEGLLAIVSDILDFSKIEAG 566

CP000441_0573: domain 1 of 1, from 285 to 350: score 72.5, E = 2e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+e+la++sHELRTPL++I g +e+L+ +e
CP000441_0 285 MKDELLATVSHELRTPLNVIYGWVEVLRS---------GEGQGFA-- 320

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i+r+a++l+r++ dlLd s + +g
CP000441_0 321 ----------HQAIDAIDRSARSLSRMVGDLLDASSLATG 350

CP000441_0487: domain 1 of 1, from 234 to 301: score 67.0, E = 7e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f a+++HELRTP++ ++g ++++l+ + ++s + +
CP000441_0 234 RLEAFNADVAHELRTPISILIGQTQVALT--------SRDRSVDRM- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l++ l+e erl+ +ind+L lsr + g
CP000441_0 272 ----------RQTLQSNLEEFERLRVIINDMLFLSRSDRG 301

CP000441_1960: domain 1 of 1, from 250 to 316: score 60.5, E = 5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f ++l+H++RTPL+ ++ +++ l +++ e+
CP000441_1 250 RLSQFSSDLAHDMRTPLANVISSSQVTLS---------RARTTEE-- 285

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++++ ++e erl+r+i+++L l+r ++
CP000441_1 286 ---------YEALIDSNIEECERLQRMIENMLFLARTDNA 316

CP000441_0450: domain 1 of 1, from 240 to 305: score 60.0, E = 6.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+L+TPL+a+++ +el+l+ ++ +
CP000441_0 240 ARRRFFADAAHQLKTPLAAVQAGVELALR---------PAEQPRV-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++ ++++ +++++lL lsr+++
CP000441_0 276 ----------NVHLRRVNGAVRQAAKIVQQLLSLSRLDSD 305

CP000441_1146: domain 1 of 1, from 161 to 226: score 58.2, E = 2.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++ ++sHELRTPL+ +r+++e+L+e + s+ +
CP000441_1 161 AQRDLTNGISHELRTPLARVRFALEMLRE----------PGSAAE-- 195

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ +le+i +++ l++Li+ L+++r+e
CP000441_1 196 ---------YHGALESIAQDVTELEELIDMSLTYARLEYS 226

CP000441_1135: domain 1 of 1, from 233 to 298: score 56.3, E = 7.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++HELRTP+ +++ ++lL++ ++ s+e
CP000441_1 233 LQRHFIADAAHELRTPIMGLSIQSQLLRR---------AATSDER-- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ + rl +L ++lL+l+r+e
CP000441_1 269 ----------EQILAQIHAGTTRLGHLAEQLLTLARLEPD 298

CP000441_1920: domain 1 of 1, from 235 to 300: score 53.0, E = 6.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl ++sHELRTPL aI g +e+Ll+ ++s+
CP000441_1 235 AKNAFLGMVSHELRTPLQAICGSIEILLA---------RPQSDAN-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++a +l++L+ dl d+ ++++
CP000441_1 271 ----------LKTIRRLQNSASSLEALVKDLTDYIKLRST 300

CP000441_1860: domain 1 of 1, from 157 to 225: score 44.8, E = 1.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+a+l+HELR+ L+ +r ++ +L+ + ++el++
CP000441_1 157 RLDVFIATLAHELRNQLAPLRHTIGILQG------LPSSELGPAL-- 195

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++++r++e+l rL++dlLd+ ri +
CP000441_1 196 ----------TQCKDIADRQIEQLVRLVDDLLDIGRIKSD 225

CP000441_0002: domain 1 of 1, from 28 to 95: score 42.9, E = 4.7e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ l+++sH+LR PL+a+ a +L+++l + +++
CP000441_0 28 LRDQALSTASHDLRSPLNAMHSWAYVLERQL-------ASADPSL-- 65

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ +++ +Li+d+Ld r+e+
CP000441_0 66 ----------QRALAGIRTGIDQQVALIDDVLDAPRAETR 95

CP000441_1467: domain 1 of 1, from 402 to 470: score 32.2, E = 5e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++a+l HEL++PL aIr++++ ++++++ ++++
CP000441_1 402 VLGQMAAGLTHELNQPLVAIRTLCDNARTFFE------RGQPAPA-- 440

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i + ++++ L +l +++r
CP000441_1 441 ----------YANLERIGKLVDSMAVLTGELKTFARKPDV 470

CP000441_2097: domain 1 of 1, from 241 to 298: score 29.7, E = 2.6e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H++RTPL+ + + +elL ++ ++ +
CP000441_2 241 AMQRFIADAAHQMRTPLARLDAQIELLDG---------EADPARH-- 276

peLRledpeyreyletilreaerllrLindlL<-*
+ l+ ++ + rL +lL
CP000441_2 277 ----------AARLDALRATSADVGRLTGQLL 298


Histogram of all scores:
score obs exp (one = represents 9 sequences)
----- --- ---
-14 5 0|=
-13 20 1|*==
-12 67 53|=====*==
-11 214 278|======================== *
-10 400 515|============================================= *
-9 488 532|======================================================= *
-8 426 398|============================================*===
-7 288 251|===========================*====
-6 203 144|===============*=======
-5 95 79|========*==
-4 53 42|====*=
-3 30 22|==*=
-2 15 11|=*
-1 12 6|*=
0 3 3|*
1 6 1|*
2 2 0|=
> 3 19 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 93.2939
P(chi-square) = 3.761e-15

Total sequences searched: 2346

Whole sequence top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: