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Classification of phyla is from NCBI page
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76 projects found  

4 accessions found for Burkholderia cenocepacia HI2424  

Data for CP000459  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000459.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000459_1458 CDS_1613583-1617005 81.6 5.9e-23 1
CP000459_1198 CDS_1322515-1324515 71.2 5e-20 1
CP000459_0506 CDS_533906-535330 68.7 2.6e-19 1
CP000459_1111 CDS_1228765-1227281 67.0 8e-19 1
CP000459_1070 CDS_1181867-1183291 61.0 4e-17 1
CP000459_0235 CDS_240376-238967 59.5 1e-16 1
CP000459_1759 CDS_1945808-1944678 59.1 1.4e-16 1
CP000459_1618 CDS_1785607-1784156 57.5 3.9e-16 1
CP000459_1746 CDS_1923209-1924576 54.3 3.1e-15 1
CP000459_0194 CDS_200461-198629 52.3 1.2e-14 1
CP000459_2630 CDS_2936627-2935542 44.7 1.7e-12 1
CP000459_0676 CDS_716437-715658 39.1 6.2e-11 1
CP000459_0031 CDS_37732-39177 36.4 3.8e-10 1
CP000459_2007 CDS_2238727-2236829 33.6 2.4e-09 1
CP000459_0414 CDS_434815-433391 30.6 1.6e-08 1
CP000459_0266 CDS_269775-271160 30.0 2.5e-08 1
CP000459_2161 CDS_2431185-2433089 26.9 1.9e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000459_1458 1/1 686 753 .. 1 87 [] 81.6 5.9e-23
CP000459_1198 1/1 282 347 .. 1 87 [] 71.2 5e-20
CP000459_0506 1/1 242 308 .. 1 87 [] 68.7 2.6e-19
CP000459_1111 1/1 234 301 .. 1 87 [] 67.0 8e-19
CP000459_1070 1/1 244 309 .. 1 87 [] 61.0 4e-17
CP000459_0235 1/1 247 313 .. 1 87 [] 59.5 1e-16
CP000459_1759 1/1 161 226 .. 1 87 [] 59.1 1.4e-16
CP000459_1618 1/1 255 320 .. 1 87 [] 57.5 3.9e-16
CP000459_1746 1/1 230 295 .. 1 87 [] 54.3 3.1e-15
CP000459_0194 1/1 235 300 .. 1 87 [] 52.3 1.2e-14
CP000459_2630 1/1 134 198 .. 1 87 [] 44.7 1.7e-12
CP000459_0676 1/1 28 95 .. 1 87 [] 39.1 6.2e-11
CP000459_0031 1/1 257 319 .. 1 80 [. 36.4 3.8e-10
CP000459_2007 1/1 404 474 .. 1 87 [] 33.6 2.4e-09
CP000459_0414 1/1 241 298 .. 1 79 [. 30.6 1.6e-08
CP000459_0266 1/1 247 305 .. 1 87 [] 30.0 2.5e-08
CP000459_2161 1/1 398 466 .. 1 87 [] 26.9 1.9e-07

Alignments of top-scoring domains:
CP000459_1458: domain 1 of 1, from 686 to 753: score 81.6, E = 5.9e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+ +++lsHELRTPL++I+gya+lLl +el++
CP000459_1 686 AKSRYVSGLSHELRTPLNSILGYAQLLLQ-------AKEELTPMR-- 723

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ti+r++e+ll+L++ lLd++rieag
CP000459_1 724 ----------YNAVRTIHRSGEHLLALVDGLLDIARIEAG 753

CP000459_1198: domain 1 of 1, from 282 to 347: score 71.2, E = 5e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+e+la++sHELRTPL++I g +e+L++ ++
CP000459_1 282 LKDELLATVSHELRTPLNVIYGWVEVLRN---------ADGQGFA-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i+r+a++l++++ dlLd s + +g
CP000459_1 318 ----------QQAVDAIDRSARSLSHMVADLLDASSLATG 347

CP000459_0506: domain 1 of 1, from 242 to 308: score 68.7, E = 2.6e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f +nl+H++RTPLt ++++a++ l +++s+++
CP000459_0 242 RLSQFSSNLAHDMRTPLTNLQAAAQVVLS---------QPRSADE-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr +e+ ++e +rl+r+i+d+L l+r e+
CP000459_0 278 ---------YRSVIESSIDEYQRLSRMIEDMLFLARSEQA 308

CP000459_1111: domain 1 of 1, from 234 to 301: score 67.0, E = 8e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f a+++HELRTP++ ++g ++++l+ + ++s + +
CP000459_1 234 RLEAFNADVAHELRTPISILIGQTQVALT--------SRDRSVDRM- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l++ l+e erl+ +ind+L lsr + g
CP000459_1 272 ----------RQTLQSNLEEFERLRVIINDMLFLSRSDRG 301

CP000459_1070: domain 1 of 1, from 244 to 309: score 61.0, E = 4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+L+TPL+a+++ +el+l+ ++ +
CP000459_1 244 ARRRFFADAAHQLKTPLAAVQAGVELALR---------PDEQPRA-- 279

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++ ++++ +++++lL lsr+++
CP000459_1 280 ----------NVHLRRANGAVRQAAKIVQQLLSLSRLDSD 309

CP000459_0235: domain 1 of 1, from 247 to 313: score 59.5, E = 1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f ++l+H++RTPL+ ++ +++ l +++ ++
CP000459_0 247 RLSQFSSDLAHDMRTPLANVISSSQITLS---------RARTTDE-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++e+ ++e erl+r+i+++L l+r ++
CP000459_0 283 ---------YEALIESNIEECERLQRMIENMLFLARTDNA 313

CP000459_1759: domain 1 of 1, from 161 to 226: score 59.1, E = 1.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++ ++sHELRTPL+ +r+++e+L+e + s+ +
CP000459_1 161 AQRDLTNGISHELRTPLARVRFALEMLRE----------PGSAAE-- 195

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ +l++i +++ l++Li+ L+++r+e
CP000459_1 196 ---------YQGALDSIAQDVTELEELIDMSLTYARLEYS 226

CP000459_1618: domain 1 of 1, from 255 to 320: score 57.5, E = 3.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + +l HE++ PL+aI+g+aelL+e +++ r
CP000459_1 255 YVETYIHTLTHEMKSPLAAISGAAELLQE----------DMPVANR- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+++e i+r+a rl+++i+ lL l+ e+
CP000459_1 291 ----------RRFTENIRRQAGRLEQMIRKLLALAEVEQK 320

CP000459_1746: domain 1 of 1, from 230 to 295: score 54.3, E = 3.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++HELRTP+ +++ ++lL++ +++ e+r
CP000459_1 230 LQRHFIADAAHELRTPIMGLSIQSQLLRR----------AATVEER- 265

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l i+ + rl +L ++lL+l+r+e
CP000459_1 266 ----------EHILAQIQAGTTRLGHLAEQLLTLARLEPD 295

CP000459_0194: domain 1 of 1, from 235 to 300: score 52.3, E = 1.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl ++sHELRTPL aI g +e+Ll+ ++s+
CP000459_0 235 AKNAFLGMVSHELRTPLQAICGSIEILLA---------RPQSDAN-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++a +l++L+ dl d+ ++++
CP000459_0 271 ----------LKTIRRLQNSALSLEALVKDLTDYIKLRST 300

CP000459_2630: domain 1 of 1, from 134 to 198: score 44.7, E = 1.7e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ + a+++HELRTP+t++rg ++ L e + ++ +
CP000459_2 134 EQTFWNAAIAHELRTPVTVLRGRLQGLAE---------GVFTPSD-- 169

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++l ++e l rLi+dl+ s +++g
CP000459_2 170 -----------ALYRSLLVQVEGLTRLIEDLRVVSLADSG 198

CP000459_0676: domain 1 of 1, from 28 to 95: score 39.1, E = 6.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ l+++sH+LR PL+a+ a +L+++l +++++
CP000459_0 28 LRDQALSTASHDLRSPLNAMHSWAYVLERQL-------ANADPNL-- 65

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ +++ +Li+ +Ld r+e+
CP000459_0 66 ----------QRALAGIRTGIDQQVALIDGVLDAPRAETR 95

CP000459_0031: domain 1 of 1, from 257 to 319: score 36.4, E = 3.8e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+l+HEL++PLtaI +++ ++++ ld t+ + +
CP000459_0 257 TLGEMAAGLAHELNQPLTAIVTHTRAAERMLD------TPSERDSV- 296

peLRledpeyreyletilreaerllrLindlLd<-*
r++l+t +a+r +++++l++
CP000459_0 297 ----------RRALQTSVAQAKRAAAILDRLRT 319

CP000459_2007: domain 1 of 1, from 404 to 474: score 33.6, E = 2.4e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++a+++HE +PL+aI ++ e+ + + ++s+++
CP000459_2 404 MLGELAASIAHEVTQPLAAIVTAGEAGMR--------WIKRSPPD-- 440

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e++ +l + ++a+r + i +++ +++ + +
CP000459_2 441 ------FTEVQYALGQMTHDARRATQVIHQIRSMAQRRDP 474

CP000459_0414: domain 1 of 1, from 241 to 298: score 30.6, E = 1.6e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H++RTPL+ + + +elL + ++ +
CP000459_0 241 AMQRFIADAAHQMRTPLARLDAQIELLDG---------ESDPARH-- 276

peLRledpeyreyletilreaerllrLindlL<-*
+ l+ ++ + rL +lL
CP000459_0 277 ----------AARLDALRATSSDVGRLTGQLL 298

CP000459_0266: domain 1 of 1, from 247 to 305: score 30.0, E = 2.5e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++fla+++HEL TPLt +rg +el ++ s +
CP000459_0 247 VQQQFLADAAHELQTPLTLVRGQIEL--Q---------PDISQKA-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+lre++ + r++ +lL l+ +
CP000459_0 281 ---------------LLLREIDLMARQVKQLLHLAEVSEA 305

CP000459_2161: domain 1 of 1, from 398 to 466: score 26.9, E = 1.9e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++a+l HEL++PL aIr++++ ++++++ ++++
CP000459_2 398 VLGQMAAGLTHELNQPLVAIRTLCDNARTFFE------RGQPAPA-- 436

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le++ + ++ + L +l +++r
CP000459_2 437 ----------LANLERVGKLVDGMAVLTGELKTFARKPDV 466


Histogram of all scores:
score obs exp (one = represents 10 sequences)
----- --- ---
-14 10 0|=
-13 15 2|*=
-12 92 61|======*===
-11 231 318|======================== *
-10 464 590|=============================================== *
-9 533 609|====================================================== *
-8 505 456|=============================================*=====
-7 345 287|============================*======
-6 205 165|================*====
-5 123 90|========*====
-4 66 48|====*==
-3 35 25|==*=
-2 12 13|=*
-1 11 7|*=
0 6 3|*
1 5 1|*
2 3 0|=
> 3 25 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 125.2842
P(chi-square) = 1.562e-21

Total sequences searched: 2686

Whole sequence top hits:
tophits_s report:
Total hits: 17
Satisfying E cutoff: 17
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 17
Satisfying E cutoff: 17
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: