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1 accessions found for Methanosaeta thermophila PT  

Data for CP000477  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000477.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000477_0374 CDS_383999-389077 94.5 8.2e-27 1
CP000477_0064 CDS_54727-55860 81.4 4.1e-23 1
CP000477_1462 CDS_1610820-1613105 50.0 3.4e-14 1
CP000477_0618 CDS_657385-655244 46.0 4.6e-13 1
CP000477_1486 CDS_1644275-1646098 34.2 1e-09 1
CP000477_1493 CDS_1651160-1652983 34.2 1e-09 1
CP000477_1500 CDS_1658045-1659868 34.2 1e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000477_0374 1/1 1099 1164 .. 1 87 [] 94.5 8.2e-27
CP000477_0064 1/1 147 215 .. 1 87 [] 81.4 4.1e-23
CP000477_1462 1/1 545 613 .. 1 87 [] 50.0 3.4e-14
CP000477_0618 1/1 481 549 .. 1 87 [] 46.0 4.6e-13
CP000477_1486 1/1 378 446 .. 1 87 [] 34.2 1e-09
CP000477_1493 1/1 378 446 .. 1 87 [] 34.2 1e-09
CP000477_1500 1/1 378 446 .. 1 87 [] 34.2 1e-09

Alignments of top-scoring domains:
CP000477_0374: domain 1 of 1, from 1099 to 1164: score 94.5, E = 8.2e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k eflan+sHE+RTPL+aI+g++ lLl+ t+ ++eq
CP000477_0 1099 SKAEFLANMSHEIRTPLNAIIGMSGLLLR---------TNVTPEQ-- 1134

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r y++ i+++++ ll+++ d+Ldlsrie+g
CP000477_0 1135 ----------RSYVSAIQSSGNALLEMLADILDLSRIEEG 1164

CP000477_0064: domain 1 of 1, from 147 to 215: score 81.4, E = 4.1e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ksef++++sHELRTPLt+I y+e+ ++++ ++l++ q
CP000477_0 147 IKSEFVSMVSHELRTPLTVINSYIEMFEDGM------LGDLTDVQ-- 185

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l+ i+++++ + +L+nd+Ld+ ri++
CP000477_0 186 ----------KEKLQLIRSQTDTMIQLVNDMLDILRIGSR 215

CP000477_1462: domain 1 of 1, from 545 to 613: score 50.0, E = 3.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+ ++sH+LR PL +I+g+a l++ +l ++ + e++
CP000477_1 545 EIESFVYTVSHDLRRPLITISGLAGLAEFDL-------EKGNLEKA- 583

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re l+t++r+ e +++L++d+L+lsri+
CP000477_1 584 ----------RESLRTVQRSCENMDALLRDILELSRIGKV 613

CP000477_0618: domain 1 of 1, from 481 to 549: score 46.0, E = 4.6e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sH+LR PL +I+g++ L+e+l ++ ++++
CP000477_0 481 EMERFVYTVSHDLRSPLITILGFIGYLREDL------RSGQTDKV-- 519

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ i++++ ++rL+ + L+lsri+
CP000477_0 520 ----------ESDIRFIENSVLKMDRLLTNTLELSRIGRV 549

CP000477_1486: domain 1 of 1, from 378 to 446: score 34.2, E = 1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sH+LR PL +++g++ L+++ +k ++++
CP000477_1 378 EMERFIYTVSHDLRSPLITVSGFLGFLRDDIEK-----GAWDKVG-- 417

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e +++++ ++ ++ L++d L+lsri+
CP000477_1 418 -----------EDIDILEGAITKMDMLLQDTLELSRIGRM 446

CP000477_1493: domain 1 of 1, from 378 to 446: score 34.2, E = 1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sH+LR PL +++g++ L+++ +k ++++
CP000477_1 378 EMERFIYTVSHDLRSPLITVSGFLGFLRDDIEK-----GAWDKVG-- 417

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e +++++ ++ ++ L++d L+lsri+
CP000477_1 418 -----------EDIDILEGAITKMDMLLQDTLELSRIGRM 446

CP000477_1500: domain 1 of 1, from 378 to 446: score 34.2, E = 1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sH+LR PL +++g++ L+++ +k ++++
CP000477_1 378 EMERFIYTVSHDLRSPLITVSGFLGFLRDDIEK-----GAWDKVG-- 417

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e +++++ ++ ++ L++d L+lsri+
CP000477_1 418 -----------EDIDILEGAITKMDMLLQDTLELSRIGRM 446


Histogram of all scores:
score obs exp (one = represents 6 sequences)
----- --- ---
-14 6 0|=
-13 16 1|*==
-12 73 38|======*======
-11 154 201|========================== *
-10 287 372|================================================ *
-9 316 385|===================================================== *
-8 293 288|===============================================*=
-7 221 181|==============================*======
-6 128 104|=================*====
-5 68 57|=========*==
-4 50 30|====*====
-3 30 16|==*==
-2 18 8|=*=
-1 9 4|*=
0 8 2|*=
1 6 1|*
2 2 0|=
> 3 11 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 123.6676
P(chi-square) = 9.103e-22

Total sequences searched: 1696

Whole sequence top hits:
tophits_s report:
Total hits: 7
Satisfying E cutoff: 7
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 7
Satisfying E cutoff: 7
Total memory: 23K


Acknowledgements:

This research is funded by:

Developed by: