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Classification of phyla is from NCBI page
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106 projects found  

1 accessions found for Mycobacterium smegmatis str. MC2 155  

Data for CP000480  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000480.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000480_4817 CDS_5087411-5085828 90.8 3.5e-25 1
CP000480_2811 CDS_2979652-2978144 85.8 9.5e-24 1
CP000480_0972 CDS_1065556-1064543 74.9 1.2e-20 1
CP000480_0916 CDS_1016604-1017758 71.5 1e-19 1
CP000480_1818 CDS_1951266-1952852 70.2 2.4e-19 1
CP000480_5675 CDS_5936157-5934730 69.5 3.9e-19 1
CP000480_5302 CDS_5569535-5568015 59.3 3.1e-16 1
CP000480_5213 CDS_5473206-5475725 57.6 9.2e-16 1
CP000480_2701 CDS_2857979-2859376 54.1 8.7e-15 1
CP000480_5473 CDS_5756171-5757511 52.0 3.6e-14 1
CP000480_5928 CDS_6192889-6191312 47.2 8.1e-13 1
CP000480_0237 CDS_275161-276513 45.6 2.2e-12 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000480_4817 1/1 303 370 .. 1 87 [] 90.8 3.5e-25
CP000480_2811 1/1 268 335 .. 1 87 [] 85.8 9.5e-24
CP000480_0972 1/1 110 176 .. 1 87 [] 74.9 1.2e-20
CP000480_0916 1/1 146 212 .. 1 87 [] 71.5 1e-19
CP000480_1818 1/1 269 336 .. 1 87 [] 70.2 2.4e-19
CP000480_5675 1/1 248 312 .. 1 87 [] 69.5 3.9e-19
CP000480_5302 1/1 254 326 .. 1 87 [] 59.3 3.1e-16
CP000480_5213 1/1 614 682 .. 1 87 [] 57.6 9.2e-16
CP000480_2701 1/1 241 307 .. 1 87 [] 54.1 8.7e-15
CP000480_5473 1/1 230 296 .. 1 87 [] 52.0 3.6e-14
CP000480_5928 1/1 281 349 .. 1 87 [] 47.2 8.1e-13
CP000480_0237 1/1 225 291 .. 1 87 [] 45.6 2.2e-12

Alignments of top-scoring domains:
CP000480_4817: domain 1 of 1, from 303 to 370: score 90.8, E = 3.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+aIrgy+el+++ +++el+++
CP000480_4 303 RVRQFVADASHELRTPLAAIRGYTELAQR-------KRGELPDDV-- 340

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++++e+ r+ +L++d+L l+r++ag
CP000480_4 341 ----------AHAMSRVESETSRMTQLVEDMLLLARLDAG 370

CP000480_2811: domain 1 of 1, from 268 to 335: score 85.8, E = 9.5e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPL+aI gyael + ++ + l+e +
CP000480_2 268 RMRQFITDASHELRTPLAAIHGYAELTRQDS-------SVLPETT-- 305

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l +i+ ea+r+++L++dlL l+r+++g
CP000480_2 306 ----------EYSLARIEAEAQRMNSLVSDLLLLARLDEG 335

CP000480_0972: domain 1 of 1, from 110 to 176: score 74.9, E = 1.2e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a +sH+LRTPL++Ir+ ae++ + + +++++
CP000480_0 110 SRRRLVAFVSHDLRTPLAGIRAVAEAIAD---------GVVTDDEV- 146

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + i++e+ rl ++++dl ++s+i ag
CP000480_0 147 ----------RVHAKQIEQESIRLAEMVDDLFEMSKINAG 176

CP000480_0916: domain 1 of 1, from 146 to 212: score 71.5, E = 1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a++ +ae+Ll+ ++ +++++
CP000480_0 146 TRRDFVANVSHELKTPVGAMSVLAEALLA---------SADDPDTV- 182

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ e++ e++rl ++i +l +lsr++
CP000480_0 183 ----------RRFAEKMVAESHRLADMIGELIELSRLQGA 212

CP000480_1818: domain 1 of 1, from 269 to 336: score 70.2, E = 2.4e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++++l++
CP000480_1 269 LQRRFTSDVSHELRTPLTTVRMAADLIYD-------HSEDLDPAL-- 306

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e + +e++r + L+ dlL++sr +ag
CP000480_1 307 ----------RRSTELMVNELDRFETLLADLLEISRHDAG 336

CP000480_5675: domain 1 of 1, from 248 to 312: score 69.5, E = 3.9e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ + ++
CP000480_5 248 RMRRFITDASHELRTPLTTIRGFAELYRQGA-----------ARDI- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +i++e++r+ L++dlL l+r++a+
CP000480_5 283 ----------EMLMGRIESESRRMGLLVEDLLLLARLDAQ 312

CP000480_5302: domain 1 of 1, from 254 to 326: score 59.3, E = 3.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++++++ HELRTPLt++r+++elL + ++ +g ++l+e+++
CP000480_5 254 RQARLVSDAGHELRTPLTSLRTNVELLMAAQE---PGAPPLPEDEM- 296

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ ++e l+ L+ dl dl+r +ag
CP000480_5 297 ----------AGLRADVIAQIEELSTLVGDLVDLTREDAG 326

CP000480_5213: domain 1 of 1, from 614 to 682: score 57.6, E = 9.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +l+++sH+LRTPL+a +++a+ L+ d + s+e++
CP000480_5 614 LSRSLLSAVSHDLRTPLAAAKAAASSLRS-------CDIDFSAEDT- 652

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l ti+++++ l +L+ +lLd sr+ ag
CP000480_5 653 ----------AELLATIEESVDALTALVGNLLDSSRLAAG 682

CP000480_2701: domain 1 of 1, from 241 to 307: score 54.1, E = 8.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a +sHELRTPLta+r+++e+L + ++++eqr
CP000480_2 241 SARDFAAVASHELRTPLTAMRTNLEVLST---------LDMTPEQR- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + + r r+++ + l l++ e
CP000480_2 278 ----------QEVIGDVMRTQSRIEATLTALERLAQGELT 307

CP000480_5473: domain 1 of 1, from 230 to 296: score 52.0, E = 3.6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f++ +HELRTPLta+r+++e+L + +l++eqr
CP000480_5 230 SARDFASVSAHELRTPLTAMRTNLEVLST---------LDLPDEQR- 266

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ ++r r+++ + l l++ e
CP000480_5 267 ----------KEVVNDVIRTQSRIEATLGALERLAQGELS 296

CP000480_5928: domain 1 of 1, from 281 to 349: score 47.2, E = 8.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL + +++lL++++ +++ +e
CP000480_5 281 ELEQFAYVASHDLQEPLRKVASFCQLLERRY-------GDKLDERG- 319

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+ + + a+r++ LindlL++sr +
CP000480_5 320 ----------VEYIGFAVDGAKRMQVLINDLLTFSRVGRL 349

CP000480_0237: domain 1 of 1, from 225 to 291: score 45.6, E = 2.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+an++HELRTPLta+r+ +++L+ ++l+e++r
CP000480_0 225 AAQDFAANAAHELRTPLTAMRADLDTLRI---------HDLPEDER- 261

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e + + r+ +r +++i l +l+ +
CP000480_0 262 ----------DEVVADLSRAQRRVEAIITALGQLASGQLA 291


Histogram of all scores:
score obs exp (one = represents 23 sequences)
----- --- ---
-15 4 0|=
-14 25 0|==
-13 110 5|*====
-12 315 153|======*=======
-11 626 796|============================ *
-10 1171 1476|=================================================== *
-9 1319 1525|==========================================================*
-8 1151 1141|=================================================*=
-7 844 719|===============================*=====
-6 471 414|=================*===
-5 326 227|=========*=====
-4 155 121|=====*=
-3 89 64|==*=
-2 31 33|=*
-1 34 17|*=
0 13 9|*
1 6 4|*
2 4 2|*
3 3 1|*
4 3 0|=
> 5 16 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 2591.8284
P(chi-square) = 0

Total sequences searched: 6716

Whole sequence top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: