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Classification of phyla is from NCBI page
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106 projects found  

3 accessions found for Mycobacterium sp. KMS  

Data for CP000518  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000518.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000518_3972 CDS_4217403-4215850 86.3 5.5e-24 1
CP000518_0670 CDS_728483-729661 74.1 1.6e-20 1
CP000518_0358 CDS_396121-400293 73.9 1.8e-20 1
CP000518_4649 CDS_4904445-4903024 71.7 7.3e-20 1
CP000518_1359 CDS_1462457-1464124 71.3 9.7e-20 1
CP000518_0719 CDS_768188-767154 67.8 9.7e-19 1
CP000518_4268 CDS_4518002-4520512 62.8 2.5e-17 1
CP000518_4358 CDS_4608016-4606469 60.5 1.2e-16 1
CP000518_3014 CDS_3181209-3182564 53.5 1.1e-14 1
CP000518_2708 CDS_2859502-2861085 50.3 8.6e-14 1
CP000518_4508 CDS_4771543-4772889 48.8 2.3e-13 1
CP000518_0174 CDS_188473-189759 46.1 1.3e-12 1
CP000518_2925 CDS_3083915-3085054 45.1 2.6e-12 1
CP000518_1449 CDS_1570390-1569206 44.3 4.3e-12 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000518_3972 1/1 285 352 .. 1 87 [] 86.3 5.5e-24
CP000518_0670 1/1 158 224 .. 1 87 [] 74.1 1.6e-20
CP000518_0358 1/1 351 417 .. 1 87 [] 73.9 1.8e-20
CP000518_4649 1/1 245 309 .. 1 87 [] 71.7 7.3e-20
CP000518_1359 1/1 297 364 .. 1 87 [] 71.3 9.7e-20
CP000518_0719 1/1 112 178 .. 1 87 [] 67.8 9.7e-19
CP000518_4268 1/1 607 675 .. 1 87 [] 62.8 2.5e-17
CP000518_4358 1/1 240 312 .. 1 87 [] 60.5 1.2e-16
CP000518_3014 1/1 235 301 .. 1 87 [] 53.5 1.1e-14
CP000518_2708 1/1 288 356 .. 1 87 [] 50.3 8.6e-14
CP000518_4508 1/1 231 297 .. 1 87 [] 48.8 2.3e-13
CP000518_0174 1/1 204 270 .. 1 87 [] 46.1 1.3e-12
CP000518_2925 1/1 141 205 .. 1 87 [] 45.1 2.6e-12
CP000518_1449 1/1 156 220 .. 1 87 [] 44.3 4.3e-12

Alignments of top-scoring domains:
CP000518_3972: domain 1 of 1, from 285 to 352: score 86.3, E = 5.5e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+aIrgy+el+++ ++++l+ +
CP000518_3 285 RVRQFVADASHELRTPLAAIRGYTELAQR-------HSDALPGDV-- 322

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++++e+ r+ rL++d+L l+r++ g
CP000518_3 323 ----------AHAMNRVESETARMTRLVEDMLLLARLDDG 352

CP000518_0670: domain 1 of 1, from 158 to 224: score 74.1, E = 1.6e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a+ ++ae+Ll+ ++ ++e++
CP000518_0 158 TRRDFVANVSHELKTPVGAMGLLAEALLA---------SADDPETV- 194

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ ++ +ea+rl ++i +l +lsr++ g
CP000518_0 195 ----------RRFAGKMVDEAHRLADMIGELIELSRLQGG 224

CP000518_0358: domain 1 of 1, from 351 to 417: score 73.9, E = 1.8e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ f++n+sHE+RTPLt I+g + +l+ +el+
CP000518_0 351 AKTTFFSNISHEFRTPLTLILGPLAEMLR--------TSELDVRV-- 387

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re le ++r + rl +L+n lLd+sri+ag
CP000518_0 388 ----------REELELAHRNGLRLAKLVNTLLDFSRIQAG 417

CP000518_4649: domain 1 of 1, from 245 to 309: score 71.7, E = 7.3e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ +++ e +
CP000518_4 245 RMRRFITDASHELRTPLTTIRGFAELYRQGA--------ARDVEML- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++i++e++r+ L++dlL l+r++a+
CP000518_4 283 -------------MNRIESESRRMGLLVEDLLLLARLDAQ 309

CP000518_1359: domain 1 of 1, from 297 to 364: score 71.3, E = 9.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++++l++
CP000518_1 297 LQRRFTSDVSHELRTPLTTVRMAADLIHD-------HSDDLDPAL-- 334

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e + +e++r + L++dlL++sr +ag
CP000518_1 335 ----------RRSTELMVSELDRFETLLSDLLEISRHDAG 364

CP000518_0719: domain 1 of 1, from 112 to 178: score 67.8, E = 9.7e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a +sH+LRTPL++Ir+ +e++ + + + +++
CP000518_0 112 SRRQLVAFVSHDLRTPLAGIRAVSEAIAD---------GLVGGDEV- 148

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + i++e+ rl+++++dl ++s+i ag
CP000518_0 149 ----------RAHAKHIEQESIRLSEMVDDLFEMSKINAG 178

CP000518_4268: domain 1 of 1, from 607 to 675: score 62.8, E = 2.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPL+a +++++ L+ + + s+++r
CP000518_4 607 LRRSLLSAVSHDLRTPLAAAKAAVSSLRS-------DEVDFSADDR- 645

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l t+++++++l +L+ +lLd sr+ ag
CP000518_4 646 ----------AELLATVEESVDQLTALVANLLDSSRLAAG 675

CP000518_4358: domain 1 of 1, from 240 to 312: score 60.5, E = 1.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++++++ HELRTPLt++r+++elL + + ++g + l+ee++
CP000518_4 240 RQARLVSDAGHELRTPLTSLRTNVELLMASQ---APGAPRLPEEEM- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ ++e l+ L+ dl dl+r eag
CP000518_4 283 ----------AGLRADVIAQIEELSTLVGDLVDLTRDEAG 312

CP000518_3014: domain 1 of 1, from 235 to 301: score 53.5, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a +sHELRTPLta+r+++e+L + ++++eqr
CP000518_3 235 SARDFAAVASHELRTPLTAMRTNLEVLST---------LDMTDEQR- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ + r r+++ + l l++ e
CP000518_3 272 ----------KEVINDVVRTQTRIEATLTALERLAQGELT 301

CP000518_2708: domain 1 of 1, from 288 to 356: score 50.3, E = 8.6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL + +++lL++++ +++ +e
CP000518_2 288 ELEQFAYVASHDLQEPLRKVASFCQLLEKRY-------GDKLDERG- 326

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey++ + + a+r++ LindlL++sr +
CP000518_2 327 ----------VEYIKYAVDGAKRMQVLINDLLTFSRVGRL 356

CP000518_4508: domain 1 of 1, from 231 to 297: score 48.8, E = 2.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f++ +HELRTPLta+r+++e+L + +l +eqr
CP000518_4 231 SARDFASVSAHELRTPLTAMRTNLEVLAT---------LDLADEQR- 267

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ ++r r+++ ++ l l++ e
CP000518_4 268 ----------KEVINDVIRTQSRIEATLSALERLAQGELS 297

CP000518_0174: domain 1 of 1, from 204 to 270: score 46.1, E = 1.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+an++HELRTPLta+r+ +++L+ ++l+e++r
CP000518_0 204 AAQDFAANAAHELRTPLTAMRADLDTLRI---------HDLPEDER- 240

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + + r+ +r +++i l +l+ +
CP000518_0 241 ----------AEVVADLSRAQRRVEAIITALGQLASGQLA 270

CP000518_2925: domain 1 of 1, from 141 to 205: score 45.1, E = 2.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++++l+HE+RTPL+++ +y e++++++ l++e+
CP000518_2 141 TRRRLFSDLAHEIRTPLAVLEAYFEAIEDGV-------RSLTPET-- 178

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ rl r dl l+r+e+
CP000518_2 179 -------------AAMLRDQTGRLVRFAGDLGALARAEES 205

CP000518_1449: domain 1 of 1, from 156 to 220: score 44.3, E = 4.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ +l+HE+RTP++++ +y+e+L++++ +l++++
CP000518_1 156 TRQQLFGDLAHEIRTPVAVLDAYIEALEDGV-------RTLTPQT-- 193

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++rl r d+ l+r+e+
CP000518_1 194 -------------AAMLRDQTRRLVRFSGDVAALARAEES 220


Histogram of all scores:
score obs exp (one = represents 19 sequences)
----- --- ---
-15 2 0|=
-14 11 0|=
-13 60 4|*===
-12 226 124|======*=====
-11 508 647|=========================== *
-10 932 1200|================================================== *
-9 1105 1239|==========================================================*
-8 985 928|================================================*===
-7 685 585|==============================*======
-6 385 336|=================*===
-5 244 184|=========*===
-4 146 98|=====*==
-3 55 52|==*
-2 45 27|=*=
-1 27 14|*=
0 11 7|*
1 6 3|*
2 5 2|*
3 3 1|*
4 1 0|=
> 5 18 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 280.1799
P(chi-square) = 0

Total sequences searched: 5460

Whole sequence top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: