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Thermotogae
Classification of phyla is from NCBI page
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2 accessions found for Burkholderia mallei SAVP1  

Data for CP000526  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000526.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000526_1276 CDS_1274651-1275961 92.0 8.4e-26 1
CP000526_1071 CDS_1069107-1071971 66.0 1.9e-18 1
CP000526_2610 CDS_2646800-2645283 61.8 3.1e-17 1
CP000526_2206 CDS_2242917-2241775 61.8 3.1e-17 1
CP000526_3310 CDS_3351508-3352974 60.0 1e-16 1
CP000526_0595 CDS_612409-613725 56.0 1.4e-15 1
CP000526_0978 CDS_975467-976780 54.5 3.6e-15 1
CP000526_1378 CDS_1368997-1370961 52.5 1.4e-14 1
CP000526_3199 CDS_3229942-3231321 49.7 8.2e-14 1
CP000526_2187 CDS_2215519-2218176 42.1 1.2e-11 1
CP000526_2738 CDS_2784631-2782223 41.3 2e-11 1
CP000526_1941 CDS_1958264-1959601 39.7 5.6e-11 1
CP000526_2851 CDS_2899199-2900479 27.1 2.1e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000526_1276 1/1 206 272 .. 1 87 [] 92.0 8.4e-26
CP000526_1071 1/1 638 709 .. 1 87 [] 66.0 1.9e-18
CP000526_2610 1/1 271 336 .. 1 87 [] 61.8 3.1e-17
CP000526_2206 1/1 152 220 .. 1 87 [] 61.8 3.1e-17
CP000526_3310 1/1 233 298 .. 1 87 [] 60.0 1e-16
CP000526_0595 1/1 213 278 .. 1 87 [] 56.0 1.4e-15
CP000526_0978 1/1 219 277 .. 1 87 [] 54.5 3.6e-15
CP000526_1378 1/1 45 110 .. 1 87 [] 52.5 1.4e-14
CP000526_3199 1/1 238 304 .. 1 87 [] 49.7 8.2e-14
CP000526_2187 1/1 636 706 .. 1 87 [] 42.1 1.2e-11
CP000526_2738 1/1 540 612 .. 1 87 [] 41.3 2e-11
CP000526_1941 1/1 227 286 .. 1 87 [] 39.7 5.6e-11
CP000526_2851 1/1 201 270 .. 1 87 [] 27.1 2.1e-07

Alignments of top-scoring domains:
CP000526_1276: domain 1 of 1, from 206 to 272: score 92.0, E = 8.4e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt+++g++e+++e +ls+++r
CP000526_1 206 MRRDFVANVSHELKTPLTVLSGFLETMRE---------LPLSDDER- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle ++++a r+++++ dlL l+++e +
CP000526_1 243 ----------ARYLELMEQQASRMRHIVTDLLVLAKLEGE 272

CP000526_1071: domain 1 of 1, from 638 to 709: score 66.0, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPLtaI g++++L + + g t +++ r
CP000526_1 638 LRNSLLSAISHDLRTPLTAIVGLSSMLAN-----ARGATREGSPARE 679

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ i++ea r+ ++ +lLd++r++ag
CP000526_1 680 ----------DELVDAIHDEALRMTGIVTNLLDMARLQAG 709

CP000526_2610: domain 1 of 1, from 271 to 336: score 61.8, E = 3.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ae +l+ +e +++
CP000526_2 271 LQKRFIADAAHQMKTPLAGLRTQAEFALR---------HEVNADV-- 306

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ le i ++e+ rL+ +lL l+r+e+
CP000526_2 307 ----------AHSLEQIATSSEQAARLVTQLLALARAENR 336

CP000526_2206: domain 1 of 1, from 152 to 220: score 61.8, E = 3.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++nl+HE+++PL +Irg+a+lL+ el +e+ +++
CP000526_2 152 VNKQLIRNLAHEIKNPLGGIRGAAQLLEFEL-------GERERDEL- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey+++i++e++rl+ L+++lL+ r +
CP000526_2 191 ----------REYTQVIIKESDRLQTLVDRLLEPHRHPHI 220

CP000526_3310: domain 1 of 1, from 233 to 298: score 60.0, E = 1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLtaI+++ae + +++++q+
CP000526_3 233 AQRKFIADAAHQLRTPLTAIKLHAEQAAV----------ARDPQQA- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++++a+r rL n+lL l+r+e g
CP000526_3 269 ----------LTAVRELRSAADRAVRLSNQLLSLARAEPG 298

CP000526_0595: domain 1 of 1, from 213 to 278: score 56.0, E = 1.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+a++ a+l + ++++ r
CP000526_0 213 TQKAFVADAAHELRTPLAAVQIQAQLVAR----------AQDDVSR- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re++ +++ + r rL ++lL l+r+e g
CP000526_0 249 ----------REAIVDLQSGVTRATRLAEQLLALARAEPG 278

CP000526_0978: domain 1 of 1, from 219 to 277: score 54.5, E = 3.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+LRTPL+ +r+ ae++ +
CP000526_0 219 DRAVMLAGVAHDLRTPLARMRLRAEMMDD------------------ 247

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + + r+++++ ++++++L ++ +a
CP000526_0 248 ----------ARLRDGVVRDVDSMTHIVDQFLVFAHGDAD 277

CP000526_1378: domain 1 of 1, from 45 to 110: score 52.5, E = 1.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + la++sHELR P++++++++el + + l +eq
CP000526_1 45 ASRGSLATASHELRAPVNGMLALVELVRQ---------GLLAPEQ-- 80

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++++++l r +nd+Ld + ieag
CP000526_1 81 ----------QRLLGLVQDSGQSLARVLNDILDHASIEAG 110

CP000526_3199: domain 1 of 1, from 238 to 304: score 49.7, E = 8.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++H+LRTP+++I + ++ ++ e ++ +
CP000526_3 238 TQRRFIADAAHQLRTPIAVIDTQIQCARQ---------RENGDAAL- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +++r+++r+ + + lL l+ +ea
CP000526_3 275 ----------AALLASMQRSSRRMADVTDKLLLLAHAEAA 304

CP000526_2187: domain 1 of 1, from 636 to 706: score 42.1, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL++PL+aI y++ l+ l +++ +s+e++
CP000526_2 636 TMGEMASSIAHELNQPLAAINNYCSGTLA-----LVKSGRASPETL- 676

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le+ ++a r ++ +++++ + ++
CP000526_2 677 ----------APALEKTAQQALRAGMIVKRIREFVKRSEP 706

CP000526_2738: domain 1 of 1, from 540 to 612: score 41.3, E = 2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l +++ls ++ +
CP000526_2 540 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL------SDKLSQPD-A 579

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ L ++ ti +++ + r+++d++d++r
CP000526_2 580 DVL-------KRGATTIVNQVAAMKRMVDDFRDYARTPPA 612

CP000526_1941: domain 1 of 1, from 227 to 286: score 39.7, E = 5.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ +
CP000526_1 227 DRALMLAGISHDLRTPLARLRLETEMSPSD----------------- 256

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + +++e+++r+i + d++r +
CP000526_1 257 ----------QATKDAMVDDIEQMDRIIAAFIDYARPAQR 286

CP000526_2851: domain 1 of 1, from 201 to 270: score 27.1, E = 2.1e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ +a+++HE+ TPL++I +++e L+e a +t+++
CP000526_2 201 ALGVQAATVAHEMGTPLSTIAMLTEELRE------AARTDAGLAR-- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y l++++++ ++ + + +l+ + +
CP000526_2 240 ---------YDADLKVLEEQMSQCTSALARLRSRASERPS 270


Histogram of all scores:
score obs exp (one = represents 12 sequences)
----- --- ---
-14 29 0|===
-13 75 2|*======
-12 185 78|======*=========
-11 344 409|============================= *
-10 590 759|================================================== *
-9 677 784|========================================================= *
-8 596 587|================================================*=
-7 387 370|==============================*==
-6 248 213|=================*===
-5 149 116|=========*===
-4 68 62|=====*
-3 50 33|==*==
-2 24 17|=*
-1 7 9|*
0 8 4|*
1 1 2|*
2 1 1|*
3 0 0|
> 4 16 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 233.2246
P(chi-square) = 1.698e-313

Total sequences searched: 3455

Whole sequence top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: