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Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
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Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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76 projects found  

3 accessions found for Acidovorax sp. JS42  

Data for CP000539  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000539.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000539_2271 CDS_2516968-2515571 88.8 8.1e-25 1
CP000539_0636 CDS_678520-681933 81.2 1.1e-22 1
CP000539_3485 CDS_3833521-3835221 72.2 4e-20 1
CP000539_0548 CDS_580146-582173 67.0 1.2e-18 1
CP000539_3846 CDS_4253806-4252325 66.9 1.3e-18 1
CP000539_1167 CDS_1261671-1262759 65.6 3e-18 1
CP000539_1413 CDS_1521369-1519984 62.0 3.2e-17 1
CP000539_2613 CDS_2889959-2891362 59.6 1.5e-16 1
CP000539_0639 CDS_683403-684551 57.3 6.7e-16 1
CP000539_3743 CDS_4135188-4132900 56.4 1.2e-15 1
CP000539_1576 CDS_1699441-1698038 56.0 1.5e-15 1
CP000539_0192 CDS_211889-210609 52.1 1.9e-14 1
CP000539_0010 CDS_10828-13482 51.8 2.4e-14 1
CP000539_2337 CDS_2588764-2590224 50.3 6.4e-14 1
CP000539_1320 CDS_1427829-1429187 49.1 1.4e-13 1
CP000539_1858 CDS_2026233-2024071 49.0 1.5e-13 1
CP000539_1039 CDS_1114007-1112475 45.3 1.7e-12 1
CP000539_1876 CDS_2048354-2046999 44.5 2.7e-12 1
CP000539_3023 CDS_3334242-3335747 38.9 1.1e-10 1
CP000539_2039 CDS_2248822-2251368 36.9 4e-10 1
CP000539_0627 CDS_669218-669988 32.3 8e-09 1
CP000539_3864 CDS_4278007-4275857 28.1 1.3e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000539_2271 1/1 205 271 .. 1 87 [] 88.8 8.1e-25
CP000539_0636 1/1 459 527 .. 1 87 [] 81.2 1.1e-22
CP000539_3485 1/1 327 392 .. 1 87 [] 72.2 4e-20
CP000539_0548 1/1 299 364 .. 1 87 [] 67.0 1.2e-18
CP000539_3846 1/1 256 322 .. 1 87 [] 66.9 1.3e-18
CP000539_1167 1/1 138 203 .. 1 87 [] 65.6 3e-18
CP000539_1413 1/1 239 305 .. 1 87 [] 62.0 3.2e-17
CP000539_2613 1/1 243 309 .. 1 87 [] 59.6 1.5e-16
CP000539_0639 1/1 160 225 .. 1 87 [] 57.3 6.7e-16
CP000539_3743 1/1 526 598 .. 1 87 [] 56.4 1.2e-15
CP000539_1576 1/1 248 311 .. 1 87 [] 56.0 1.5e-15
CP000539_0192 1/1 207 269 .. 1 87 [] 52.1 1.9e-14
CP000539_0010 1/1 518 583 .. 1 87 [] 51.8 2.4e-14
CP000539_2337 1/1 235 307 .. 1 87 [] 50.3 6.4e-14
CP000539_1320 1/1 224 288 .. 1 87 [] 49.1 1.4e-13
CP000539_1858 1/1 340 406 .. 1 87 [] 49.0 1.5e-13
CP000539_1039 1/1 272 336 .. 1 87 [] 45.3 1.7e-12
CP000539_1876 1/1 237 299 .. 1 87 [] 44.5 2.7e-12
CP000539_3023 1/1 255 314 .. 1 87 [] 38.9 1.1e-10
CP000539_2039 1/1 598 668 .. 1 87 [] 36.9 4e-10
CP000539_0627 1/1 32 102 .. 1 87 [] 32.3 8e-09
CP000539_3864 1/1 478 555 .. 1 87 [] 28.1 1.3e-07

Alignments of top-scoring domains:
CP000539_2271: domain 1 of 1, from 205 to 271: score 88.8, E = 8.1e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHE+RTPLt+++g++e+L++ ls e+r
CP000539_2 205 MRRDFVANVSHEIRTPLTVLMGFVETLQT---------LQLSNEER- 241

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ + ++a r+++L++dlL+lsr+e
CP000539_2 242 ----------ARYLRMMSQQAVRMQNLVQDLLTLSRLEGS 271

CP000539_0636: domain 1 of 1, from 459 to 527: score 81.2, E = 1.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++ + +a+lL + + ++l++eq
CP000539_0 459 YKSEFLANMSHELRTPLNSSLILAKLLAD------NKQQNLTAEQ-- 497

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y +ti++++ ll+Lind+Ldl++ieag
CP000539_0 498 ----------VRYAQTIHNAGTDLLNLINDILDLAKIEAG 527

CP000539_3485: domain 1 of 1, from 327 to 392: score 72.2, E = 4e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++ a+++HE+R+PL+aI + elL+e +l+++++
CP000539_3 327 AMGRMSAAVAHEIRNPLAAIVQANELLEE----------DLDDPTQ- 362

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ +++ a+rl r+ +d+Ld++r +++
CP000539_3 363 ----------KRLTHMVRQNADRLVRITEDVLDIARVQHQ 392

CP000539_0548: domain 1 of 1, from 299 to 364: score 67.0, E = 1.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++fla++sH+LR+P++a+ +++e+L+ + +s+e
CP000539_0 299 DKTRFLAAASHDLRQPMHALNLLLEALKQ---------ESRSDER-- 334

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++le+i+ +++ +++L++ lLd+sr++ag
CP000539_0 335 ----------ARLLERIEASSQAMSALLDALLDISRLDAG 364

CP000539_3846: domain 1 of 1, from 256 to 322: score 66.9, E = 1.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +fla+++H+L+TPL+++r+ a+l+++ +++ +ee
CP000539_3 256 TQKRFLADAAHQLKTPLAGLRMQADLAQR--------EGTSTEEL-- 292

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l+ i r++ r + +n+lL l+r+e g
CP000539_3 293 ----------KQSLKQIGRSSIRATHTVNQLLALARAEGG 322

CP000539_1167: domain 1 of 1, from 138 to 203: score 65.6, E = 3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a e+++nl+HE+++PL +Irg+a+lL++ el + ++
CP000539_1 138 ANKELIRNLAHEIKNPLGGIRGAAQLLEM----------ELESRDL- 173

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+++i++ea+rl++L+++lL r +
CP000539_1 174 ----------TEYTQVIIHEADRLQSLVDRLLAPHRHPHL 203

CP000539_1413: domain 1 of 1, from 239 to 305: score 62.0, E = 3.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++sef ++l+HE+RTP++ +++ ++++l+ ++++++
CP000539_1 239 RLSEFSSDLAHEIRTPISNLLTQTQVALA---------NKRDADT-- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr++l + +e +rl r+++d+L l++ + g
CP000539_1 275 ---------YRDILASNAEEFQRLARMVSDMLFLAKTDRG 305

CP000539_2613: domain 1 of 1, from 243 to 309: score 59.6, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f ++l+HELRTP++ +++ ++++l+ t++++ +
CP000539_2 243 RLTDFSSDLAHELRTPISNLLTQTQVALA---------TKRDAAT-- 278

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr++l + +e +rl r++ d+L l++ e g
CP000539_2 279 ---------YRDILASNAEEFQRLARMVADMLFLAKTERG 309

CP000539_0639: domain 1 of 1, from 160 to 225: score 57.3, E = 6.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a lsH+LR PL+aI++ a++L++ ++ +++
CP000539_0 160 INEMFMAVLSHDLRSPLSAIMAVASALQR---------APEPAKV-- 195

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++++++r+ r+i+dlLd +r+++
CP000539_0 196 ----------QALACNVQQAGRRMGRMIEDLLDVTRARQH 225

CP000539_3743: domain 1 of 1, from 526 to 598: score 56.4, E = 1.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+ +l +++l++ +++
CP000539_3 526 AWGEVARRLAHEIKNPLTPIQLSAERLEIKL------SGKLPAAEQA 566

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ti ++++ + rL+n+++d++r+ +
CP000539_3 567 VL--------TKSVKTIVDQVDAMKRLVNEFRDYARLPSA 598

CP000539_1576: domain 1 of 1, from 248 to 311: score 56.0, E = 1.5e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sH+LRTPL+++++ ++ +l+ ++l++ q+
CP000539_1 248 HQQRFVRDASHQLRTPLAVLKTQVQSALR---------GDLPPTQA- 284

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+ i + ++r +L n++L l++ e+
CP000539_1 285 -------------LREIGDTVDRATQLANQMLALAKVEQL 311

CP000539_0192: domain 1 of 1, from 207 to 269: score 52.1, E = 1.9e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +lan+sHELR PLt Ir+ +el++ ++ s+
CP000539_0 207 SHKSLLANASHELRSPLTRIRMGLELMQG---------GTPSPAF-- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
i+r + l++L++++L sr+++g
CP000539_0 243 -------------RAEIERNIAELDQLVDEILLASRLDSG 269

CP000539_0010: domain 1 of 1, from 518 to 583: score 51.8, E = 2.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f+a++ H+L +PL+a r++a+lL+ + ++
CP000539_0 518 YKTRFVAAAVHDLLQPLNAARMFASLLRG---------HLHDAAG-- 553

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ ++i+ ++ + ++n lLd+sr+e+g
CP000539_0 554 ----------RQVADSIDGALAAQDGILNSLLDISRMESG 583

CP000539_2337: domain 1 of 1, from 235 to 307: score 50.3, E = 6.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkv.lagdtelseeqr
++++a+++HELRTPLtaI++++++++ + +ag ++s++++
CP000539_2 235 HERRWTADAAHELRTPLTAIKTHVQVAQL----TlAAGNNNASPDKA 277

lpeLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l+ + + ++++ + +++lL+l+r e+
CP000539_2 278 -----------ANALRQAGEGIDHMHATLRQLLQLARVESA 307

CP000539_1320: domain 1 of 1, from 224 to 288: score 49.1, E = 1.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+ +++HELRTPLt+I +++++++ +e +e
CP000539_1 224 SQRAFTDAAAHELRTPLTVIDTHLQVARI---------SEGDEVA-- 259

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++++ ++rl+r ++++++l+r+ea+
CP000539_1 260 -----------SSLSSAEEGVKRLRRTLDQMMTLARAEAP 288

CP000539_1858: domain 1 of 1, from 340 to 406: score 49.0, E = 1.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++ +++H++++ L+aI+g++el+++ + + +
CP000539_1 340 AVGTMAGGIAHDFNNILHAILGNVELAKA---------DCPPGTPM- 376

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e l i+++++r ++L++++L++sr e +
CP000539_1 377 ----------YESLLEIDKAGRRARDLVRQILTFSRNEPP 406

CP000539_1039: domain 1 of 1, from 272 to 336: score 45.3, E = 1.7e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++ + +HELRTPL+a+r+ +e+ ++++ + +e++
CP000539_1 272 SRRQWIGDTAHELRTPLAAMRAEIEAVQDGV-------RPFDEKT-- 309

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++r++ rl +L+ dl+ +
CP000539_1 310 -------------ARRLHRQVMRLIQLVGDLRASVDMAGD 336

CP000539_1876: domain 1 of 1, from 237 to 299: score 44.5, E = 2.7e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++an++HELRTPLta r+ ++++le +
CP000539_1 237 VERALAANAAHELRTPLTAARLRLQTALE-------------HGLH- 269

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ ++ ++ +++ l+r + lL+lsr+e+
CP000539_1 270 ----------RDDVQAAIAALQTLSRRTEKLLQLSRAESS 299

CP000539_3023: domain 1 of 1, from 255 to 314: score 38.9, E = 1.1e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ ++
CP000539_3 255 DRAVMLAGISHDLRTPLARLRLETEMSVTD----------------- 284

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e + ++ +l++ i+ +Ld++r ++
CP000539_3 285 ----------DVAREHMVADIVQLDATIDKFLDYARPDTT 314

CP000539_2039: domain 1 of 1, from 598 to 668: score 36.9, E = 4e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL++PLtaI y++ + + + + see +
CP000539_2 598 TMGEMASSVAHELNQPLTAINNYCSGMVSRI-----QGGQISEEAL- 638

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++ ++a+r ++i++++ + + ++
CP000539_2 639 ----------LTALQKTAHQAQRAGQIIQRIRAFVKKSEP 668

CP000539_0627: domain 1 of 1, from 32 to 102: score 32.3, E = 8e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++fl+++sH+LR PL + y l +e +++++ +++
CP000539_0 32 AQEDFLRGVSHDLRAPLRHVTSYGALVRE-----VLQEQPPQVDEA- 72

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l t++++a+r+ ++i+ l ++r+++
CP000539_0 73 ----------LGFLATMEQSARRMAQMIDGLQAIARARSA 102

CP000539_3864: domain 1 of 1, from 478 to 555: score 28.1, E = 1.3e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldk...v.lagdtelse
+e+++ lsHEL++PL+aI+ ya l+ l+ ++ +l++ ++l +
CP000539_3 478 TVGEMASLLSHELNQPLAAISSYANGSLNLLEPapgAeLPSPQDLQD 524

eqrlpeLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++i +aer r i + d+ r + +
CP000539_3 525 VRVG-------------VQRIAAQAERAGRVIKSVHDFVRRRDQ 555


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-14 6 0|=
-13 30 3|*==
-12 144 91|======*=====
-11 338 474|========================== *
-10 696 881|====================================================== *
-9 733 909|========================================================= *
-8 715 681|====================================================*==
-7 515 429|================================*=======
-6 354 247|==================*=========
-5 204 135|==========*=====
-4 113 72|=====*===
-3 55 38|==*==
-2 41 20|=*==
-1 16 10|*=
0 8 5|*
1 9 2|*
2 2 1|*
3 2 0|=
4 1 0|=
5 0 0|
> 6 25 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 297.9573
P(chi-square) = 0

Total sequences searched: 4007

Whole sequence top hits:
tophits_s report:
Total hits: 22
Satisfying E cutoff: 22
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 22
Satisfying E cutoff: 22
Total memory: 29K


Acknowledgements:

This research is funded by:

Developed by: