Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
76 projects found  

2 accessions found for Burkholderia mallei NCTC 10229  

Data for CP000545  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000545.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000545_1259 CDS_1340456-1338138 75.9 2e-21 1
CP000545_0395 CDS_406011-407405 67.8 3.9e-19 1
CP000545_0043 CDS_43116-41737 57.8 2.6e-16 1
CP000545_0027 CDS_26343-27644 57.1 4.2e-16 1
CP000545_0109 CDS_102069-103574 55.8 9.4e-16 1
CP000545_0089 CDS_84053-82725 47.4 2.3e-13 1
CP000545_0167 CDS_153007-155472 46.5 4.1e-13 1
CP000545_0653 CDS_706983-705622 45.3 9.4e-13 1
CP000545_1890 CDS_1974475-1975644 38.0 1.1e-10 2
CP000545_1480 CDS_1566073-1567041 31.6 7e-09 1
CP000545_1634 CDS_1710402-1709623 29.0 3.9e-08 1
CP000545_1561 CDS_1641868-1642962 28.0 7.2e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000545_1259 1/1 395 460 .. 1 87 [] 75.9 2e-21
CP000545_0395 1/1 242 308 .. 1 87 [] 67.8 3.9e-19
CP000545_0043 1/1 233 298 .. 1 87 [] 57.8 2.6e-16
CP000545_0027 1/1 218 283 .. 1 87 [] 57.1 4.2e-16
CP000545_0109 1/1 240 305 .. 1 87 [] 55.8 9.4e-16
CP000545_0089 1/1 207 272 .. 1 87 [] 47.4 2.3e-13
CP000545_0167 1/1 588 656 .. 1 87 [] 46.5 4.1e-13
CP000545_0653 1/1 230 295 .. 1 87 [] 45.3 9.4e-13
CP000545_1480 1/1 86 154 .. 1 87 [] 31.6 7e-09
CP000545_1634 1/1 27 94 .. 1 87 [] 29.0 3.9e-08
CP000545_1561 1/1 143 206 .. 1 87 [] 28.0 7.2e-08

Alignments of top-scoring domains:
CP000545_1259: domain 1 of 1, from 395 to 460: score 75.9, E = 2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+e+la++sHELRTPL++I g +e+L++ + ++ q
CP000545_1 395 LKDELLATVSHELRTPLNVIYGWIEVLRN---------PVDGALQ-- 430

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i+r+a++l+r++ d+Ld s + +g
CP000545_1 431 ----------QQAIDAIDRSARSLSRMVGDILDASSLATG 460

CP000545_0395: domain 1 of 1, from 242 to 308: score 67.8, E = 3.9e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f +nl+H++RTPLt +++ a+++l ++++++
CP000545_0 242 RLSQFSSNLAHDMRTPLTNLLAEAQVALS---------KPRTADE-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+ +e+ ++e +rl+r+i+d+L l+r ++
CP000545_0 278 ---------YRDVIESSIDEYQRLSRMIEDMLFLARSDNA 308

CP000545_0043: domain 1 of 1, from 233 to 298: score 57.8, E = 2.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++HELRTP+ +++ ++lL++ ++s+++r
CP000545_0 233 LQRHFIADAAHELRTPIMGLSIQTQLLQR----------TASADER- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ + rl++L ++lL+l+r+e +
CP000545_0 269 ----------ARILAQIQAGTTRLSHLAEQLLTLARLEPE 298

CP000545_0027: domain 1 of 1, from 218 to 283: score 57.1, E = 4.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ ++sHELRTPL+ +r+++e L+e + s+ +
CP000545_0 218 TQRDLTNGISHELRTPLARVRFALESLRE----------PGSAAE-- 252

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++++i++++ l++Li+ L+++r+e
CP000545_0 253 ---------YQNAIDSIEQDVSELDELIDMSLTYARLEYS 283

CP000545_0109: domain 1 of 1, from 240 to 305: score 55.8, E = 9.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+L+TPL+a ++ +el+l+ ++ e +
CP000545_0 240 ARRRFFADAAHQLKTPLAAAQAGVELALR----------PAERERV- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++ ++++ +++++lL lsr+e+
CP000545_0 276 ----------SVHLRRVNGAVRQAAKIVQQLLSLSRLESD 305

CP000545_0089: domain 1 of 1, from 207 to 272: score 47.4, E = 2.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++ ++sHEL+TPL+ + + + lL ++++e
CP000545_0 207 QQREMMHGISHELKTPLARLEFGLALLSS---------PDAPERM-- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++r+++ l++L+ +lL++ r+e+g
CP000545_0 243 ----------RERQAALRRDVRELDELVTELLTIGRLEQG 272

CP000545_0167: domain 1 of 1, from 588 to 656: score 46.5, E = 4.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +sH+L PL a+ g ++lL++++ + l++
CP000545_0 588 DLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQ------GQLDARA-- 626

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e++ + + a r+++Li+dlL +sr +
CP000545_0 627 ----------DEFIGHAVDGATRMQSLIDDLLSYSRVGRL 656

CP000545_0653: domain 1 of 1, from 230 to 295: score 45.3, E = 9.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+an +HELRTP++a ++ ++ L + e+++e +
CP000545_0 230 AERSFAANSAHELRTPIAAALAQTQRLIA----------EAPAEPL- 265

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++++ +++ l+r ++l++l+++e g
CP000545_0 266 ----------RERARRVEGALHTLSRVSEQLMQLAKAEDG 295

CP000545_1480: domain 1 of 1, from 86 to 154: score 31.6, E = 7e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+aI+++++ + + + +s++
CP000545_1 86 ALGQMAAGITHELNQPLAAIMTLSSNAVRMAA------LGRSADL-- 124

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ le + + a r+ +++ + ++r e+
CP000545_1 125 ----------TRNLELVNDLAGRMGKIVAHMKGFARHESV 154

CP000545_1634: domain 1 of 1, from 27 to 94: score 29.0, E = 3.9e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ l+ +sH+LR PL+a+ a +L++ + ++s+e +
CP000545_1 27 VRDHALSVASHDLRSPLNAMHSWAYVLER--------RLTASDENL- 64

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ i+ +e+ +L++ d r+e+
CP000545_1 65 ----------ARALDGIRIGIEQQTKLLETTIDAPRAETR 94

CP000545_1561: domain 1 of 1, from 143 to 206: score 28.0, E = 7.2e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e l lsH++RTP t+I++++++ ++ ++ + +
CP000545_1 143 QRDEVLDFLSHDMRTPQTSILALLDVYRN---------EHGAMPPI- 179

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ a+r l+L + + l+r++++
CP000545_1 180 -------------LERIETHARRALALADGFIHLTRAQSE 206


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-15 3 0|=
-14 18 0|===
-13 55 1|*======
-12 139 49|======*===========
-11 232 258|============================= *
-10 384 478|================================================ *
-9 432 494|====================================================== *
-8 337 370|=========================================== *
-7 249 233|=============================*==
-6 130 134|================*
-5 93 73|=========*==
-4 39 39|====*
-3 16 20|==*
-2 18 10|=*=
-1 10 5|*=
0 2 2|*
1 3 1|*
> 2 17 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 207.4909
P(chi-square) = 2.07e-38

Total sequences searched: 2177

Whole sequence top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 11
Satisfying E cutoff: 11
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: