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2 accessions found for Burkholderia mallei NCTC 10247  

Data for CP000547  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000547.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000547_2228 CDS_2198023-2195708 75.9 2.2e-21 1
CP000547_1158 CDS_1149188-1147794 67.8 4.3e-19 1
CP000547_1547 CDS_1513457-1514836 57.8 2.9e-16 1
CP000547_1566 CDS_1530204-1528903 57.1 4.6e-16 1
CP000547_1477 CDS_1453235-1451730 55.8 1e-15 1
CP000547_1495 CDS_1471258-1472586 47.4 2.5e-13 1
CP000547_1412 CDS_1402285-1399820 46.5 4.4e-13 1
CP000547_1599 CDS_1564717-1563356 45.3 1e-12 1
CP000547_0595 CDS_546513-547682 38.0 1.2e-10 2
CP000547_0085 CDS_70902-71834 31.6 7.7e-09 1
CP000547_0319 CDS_282515-281736 29.0 4.2e-08 1
CP000547_0250 CDS_213969-215066 28.0 7.8e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000547_2228 1/1 394 459 .. 1 87 [] 75.9 2.2e-21
CP000547_1158 1/1 242 308 .. 1 87 [] 67.8 4.3e-19
CP000547_1547 1/1 233 298 .. 1 87 [] 57.8 2.9e-16
CP000547_1566 1/1 218 283 .. 1 87 [] 57.1 4.6e-16
CP000547_1477 1/1 240 305 .. 1 87 [] 55.8 1e-15
CP000547_1495 1/1 207 272 .. 1 87 [] 47.4 2.5e-13
CP000547_1412 1/1 588 656 .. 1 87 [] 46.5 4.4e-13
CP000547_1599 1/1 230 295 .. 1 87 [] 45.3 1e-12
CP000547_0085 1/1 74 142 .. 1 87 [] 31.6 7.7e-09
CP000547_0319 1/1 27 94 .. 1 87 [] 29.0 4.2e-08
CP000547_0250 1/1 144 207 .. 1 87 [] 28.0 7.8e-08

Alignments of top-scoring domains:
CP000547_2228: domain 1 of 1, from 394 to 459: score 75.9, E = 2.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+e+la++sHELRTPL++I g +e+L++ + ++ q
CP000547_2 394 LKDELLATVSHELRTPLNVIYGWIEVLRN---------PVDGALQ-- 429

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i+r+a++l+r++ d+Ld s + +g
CP000547_2 430 ----------QQAIDAIDRSARSLSRMVGDILDASSLATG 459

CP000547_1158: domain 1 of 1, from 242 to 308: score 67.8, E = 4.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f +nl+H++RTPLt +++ a+++l ++++++
CP000547_1 242 RLSQFSSNLAHDMRTPLTNLLAEAQVALS---------KPRTADE-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+ +e+ ++e +rl+r+i+d+L l+r ++
CP000547_1 278 ---------YRDVIESSIDEYQRLSRMIEDMLFLARSDNA 308

CP000547_1547: domain 1 of 1, from 233 to 298: score 57.8, E = 2.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++HELRTP+ +++ ++lL++ ++s+++r
CP000547_1 233 LQRHFIADAAHELRTPIMGLSIQTQLLQR----------TASADER- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ + rl++L ++lL+l+r+e +
CP000547_1 269 ----------ARILAQIQAGTTRLSHLAEQLLTLARLEPE 298

CP000547_1566: domain 1 of 1, from 218 to 283: score 57.1, E = 4.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ ++sHELRTPL+ +r+++e L+e + s+ +
CP000547_1 218 TQRDLTNGISHELRTPLARVRFALESLRE----------PGSAAE-- 252

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++++i++++ l++Li+ L+++r+e
CP000547_1 253 ---------YQNAIDSIEQDVSELDELIDMSLTYARLEYS 283

CP000547_1477: domain 1 of 1, from 240 to 305: score 55.8, E = 1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+L+TPL+a ++ +el+l+ ++ e +
CP000547_1 240 ARRRFFADAAHQLKTPLAAAQAGVELALR----------PAERERV- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++ ++++ +++++lL lsr+e+
CP000547_1 276 ----------SVHLRRVNGAVRQAAKIVQQLLSLSRLESD 305

CP000547_1495: domain 1 of 1, from 207 to 272: score 47.4, E = 2.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++ ++sHEL+TPL+ + + + lL ++++e
CP000547_1 207 QQREMMHGISHELKTPLARLEFGLALLSS---------PDAPERM-- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++r+++ l++L+ +lL++ r+e+g
CP000547_1 243 ----------RERQAALRRDVRELDELVTELLTIGRLEQG 272

CP000547_1412: domain 1 of 1, from 588 to 656: score 46.5, E = 4.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +sH+L PL a+ g ++lL++++ + l++
CP000547_1 588 DLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQ------GQLDARA-- 626

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e++ + + a r+++Li+dlL +sr +
CP000547_1 627 ----------DEFIGHAVDGATRMQSLIDDLLSYSRVGRL 656

CP000547_1599: domain 1 of 1, from 230 to 295: score 45.3, E = 1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+an +HELRTP++a ++ ++ L + e+++e +
CP000547_1 230 AERSFAANSAHELRTPIAAALAQTQRLIA----------EAPAEPL- 265

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re ++++ +++ l+r ++l++l+++e g
CP000547_1 266 ----------RERARRVEGALHTLSRVSEQLMQLAKAEDG 295

CP000547_0085: domain 1 of 1, from 74 to 142: score 31.6, E = 7.7e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+aI+++++ + + + +s++
CP000547_0 74 ALGQMAAGITHELNQPLAAIMTLSSNAVRMAA------LGRSADL-- 112

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ le + + a r+ +++ + ++r e+
CP000547_0 113 ----------TRNLELVNDLAGRMGKIVAHMKGFARHESV 142

CP000547_0319: domain 1 of 1, from 27 to 94: score 29.0, E = 4.2e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ l+ +sH+LR PL+a+ a +L++ + ++s+e +
CP000547_0 27 VRDHALSVASHDLRSPLNAMHSWAYVLER--------RLTASDENL- 64

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ i+ +e+ +L++ d r+e+
CP000547_0 65 ----------ARALDGIRIGIEQQTKLLETTIDAPRAETR 94

CP000547_0250: domain 1 of 1, from 144 to 207: score 28.0, E = 7.8e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e l lsH++RTP t+I++++++ ++ ++ + +
CP000547_0 144 QRDEVLDFLSHDMRTPQTSILALLDVYRN---------EHGAMPPI- 180

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ a+r l+L + + l+r++++
CP000547_0 181 -------------LERIETHARRALALADGFIHLTRAQSE 207


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-15 2 0|=
-14 16 0|==
-13 72 1|*========
-12 157 54|======*=============
-11 268 281|================================== *
-10 432 522|====================================================== *
-9 456 539|========================================================= *
-8 357 403|============================================= *
-7 271 254|===============================*==
-6 137 146|==================*
-5 98 80|=========*===
-4 41 43|=====*
-3 19 22|==*
-2 17 11|=*=
-1 9 6|*=
0 3 3|*
1 3 1|*
> 2 18 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 238.5788
P(chi-square) = 1.326e-314

Total sequences searched: 2376

Whole sequence top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 11
Satisfying E cutoff: 11
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: