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Classification of phyla is from NCBI page
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2 accessions found for Burkholderia pseudomallei 668  

Data for CP000570  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000570.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000570_1479 CDS_1455770-1457080 92.0 9.6e-26 1
CP000570_2001 CDS_2017891-2014643 78.0 9e-22 1
CP000570_1239 CDS_1218478-1221459 66.0 2.2e-18 1
CP000570_0804 CDS_789970-788399 61.8 3.5e-17 1
CP000570_2603 CDS_2610229-2609087 61.8 3.5e-17 1
CP000570_3943 CDS_3906963-3908429 60.0 1.2e-16 1
CP000570_0842 CDS_823905-825221 56.0 1.5e-15 1
CP000570_1090 CDS_1072161-1073474 54.5 4.1e-15 1
CP000570_1603 CDS_1580170-1582104 52.5 1.5e-14 1
CP000570_0779 CDS_767565-765730 51.2 3.5e-14 1
CP000570_0041 CDS_38076-39455 49.7 9.4e-14 1
CP000570_2584 CDS_2584487-2586994 42.1 1.4e-11 1
CP000570_0156 CDS_149776-152184 41.3 2.3e-11 1
CP000570_2330 CDS_2327369-2328706 40.0 5.1e-11 1
CP000570_0455 CDS_428870-430903 34.4 2.1e-09 1
CP000570_0186 CDS_181540-182820 27.1 2.4e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000570_1479 1/1 206 272 .. 1 87 [] 92.0 9.6e-26
CP000570_2001 1/1 493 558 .. 1 87 [] 78.0 9e-22
CP000570_1239 1/1 677 748 .. 1 87 [] 66.0 2.2e-18
CP000570_0804 1/1 289 354 .. 1 87 [] 61.8 3.5e-17
CP000570_2603 1/1 152 220 .. 1 87 [] 61.8 3.5e-17
CP000570_3943 1/1 233 298 .. 1 87 [] 60.0 1.2e-16
CP000570_0842 1/1 213 278 .. 1 87 [] 56.0 1.5e-15
CP000570_1090 1/1 219 277 .. 1 87 [] 54.5 4.1e-15
CP000570_1603 1/1 30 95 .. 1 87 [] 52.5 1.5e-14
CP000570_0779 1/1 244 309 .. 1 87 [] 51.2 3.5e-14
CP000570_0041 1/1 238 304 .. 1 87 [] 49.7 9.4e-14
CP000570_2584 1/1 586 656 .. 1 87 [] 42.1 1.4e-11
CP000570_0156 1/1 540 612 .. 1 87 [] 41.3 2.3e-11
CP000570_2330 1/1 227 286 .. 1 87 [] 40.0 5.1e-11
CP000570_0455 1/1 432 494 .. 1 81 [. 34.4 2.1e-09
CP000570_0186 1/1 201 270 .. 1 87 [] 27.1 2.4e-07

Alignments of top-scoring domains:
CP000570_1479: domain 1 of 1, from 206 to 272: score 92.0, E = 9.6e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt+++g++e+++e +ls+++r
CP000570_1 206 MRRDFVANVSHELKTPLTVLSGFLETMRE---------LPLSDDER- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle ++++a r+++++ dlL l+++e +
CP000570_1 243 ----------ARYLELMEQQASRMRHIVTDLLVLAKLEGE 272

CP000570_2001: domain 1 of 1, from 493 to 558: score 78.0, E = 9e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak f+a++sHE+RTPL+++ g++el+ + ++l +eq
CP000570_2 493 AKVAFFASMSHEIRTPLSSLVGNIELIAR---------GPLAPEQ-- 528

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ++ +a+ l +++nd+Ld+s+i+ g
CP000570_2 529 ----------QARVKAMETSARGLMQIVNDVLDFSKIDVG 558

CP000570_1239: domain 1 of 1, from 677 to 748: score 66.0, E = 2.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPLtaI g++++L + + g t +++ r
CP000570_1 677 LRNSLLSAISHDLRTPLTAIVGLSSMLAN-----ARGATREGSPARE 718

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ i++ea r+ ++ +lLd++r++ag
CP000570_1 719 ----------DELVDAIHDEALRMTGIVTNLLDMARLQAG 748

CP000570_0804: domain 1 of 1, from 289 to 354: score 61.8, E = 3.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ae +l+ +e +++
CP000570_0 289 LQKRFIADAAHQMKTPLAGLRTQAEFALR---------HEVNADV-- 324

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ le i ++e+ rL+ +lL l+r+e+
CP000570_0 325 ----------AHSLEQIATSSEQAARLVTQLLALARAENR 354

CP000570_2603: domain 1 of 1, from 152 to 220: score 61.8, E = 3.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++nl+HE+++PL +Irg+a+lL+ el +e+ +++
CP000570_2 152 VNKQLIRNLAHEIKNPLGGIRGAAQLLEFEL-------GERERDEL- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey+++i++e++rl+ L+++lL+ r +
CP000570_2 191 ----------REYTQVIIKESDRLQTLVDRLLEPHRHPHI 220

CP000570_3943: domain 1 of 1, from 233 to 298: score 60.0, E = 1.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLtaI+++ae + +++++q+
CP000570_3 233 AQRKFIADAAHQLRTPLTAIKLHAEQAAV----------ARDPQQA- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++++a+r rL n+lL l+r+e g
CP000570_3 269 ----------LTAVRELRSAADRAVRLSNQLLSLARAEPG 298

CP000570_0842: domain 1 of 1, from 213 to 278: score 56.0, E = 1.5e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+a++ a+l + ++++ r
CP000570_0 213 TQKAFVADAAHELRTPLAAVQIQAQLVAR----------AQDDVSR- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re++ +++ + r rL ++lL l+r+e g
CP000570_0 249 ----------REAIVDLQSGVTRATRLAEQLLALARAEPG 278

CP000570_1090: domain 1 of 1, from 219 to 277: score 54.5, E = 4.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+LRTPL+ +r+ ae++ +
CP000570_1 219 DRAVMLAGVAHDLRTPLARMRLRAEMMDD------------------ 247

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + + r+++++ ++++++L ++ +a
CP000570_1 248 ----------ARLRDGVVRDVDSMTHIVDQFLVFAHGDAD 277

CP000570_1603: domain 1 of 1, from 30 to 95: score 52.5, E = 1.5e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + la++sHELR P++++++++el + + l +eq
CP000570_1 30 ASRGSLATASHELRAPVNGMLALVELVRQ---------GLLAPEQ-- 65

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++++++l r +nd+Ld + ieag
CP000570_1 66 ----------QRLLGLVQDSGQSLARVLNDILDHASIEAG 95

CP000570_0779: domain 1 of 1, from 244 to 309: score 51.2, E = 3.5e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl ++sHELRTPL aI g +e+Ll+ ++se
CP000570_0 244 AKNAFLGMVSHELRTPLQAICGSIEVLLA---------RPQSEAN-- 279

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++a +l+++++dl d+ ++++
CP000570_0 280 ----------MKTIKRLQNSAASLEAQVQDLTDYIKLRST 309

CP000570_0041: domain 1 of 1, from 238 to 304: score 49.7, E = 9.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++H+LRTP+++I + ++ ++ e ++ +
CP000570_0 238 TQRRFIADAAHQLRTPIAVIDTQIQCARQ---------RENGDAAL- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +++r+++r+ + + lL l+ +ea
CP000570_0 275 ----------AALLASMQRSSRRMADVTDKLLLLAHAEAA 304

CP000570_2584: domain 1 of 1, from 586 to 656: score 42.1, E = 1.4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL++PL+aI y++ l+ l +++ +s+e++
CP000570_2 586 TMGEMASSIAHELNQPLAAINNYCSGTLA-----LVKSGRASPETL- 626

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le+ ++a r ++ +++++ + ++
CP000570_2 627 ----------APALEKTAQQALRAGMIVKRIREFVKRSEP 656

CP000570_0156: domain 1 of 1, from 540 to 612: score 41.3, E = 2.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l +++ls ++ +
CP000570_0 540 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL------SDKLSQPD-A 579

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ L ++ ti +++ + r+++d++d++r
CP000570_0 580 DVL-------KRGATTIVNQVAAMKRMVDDFRDYARTPPA 612

CP000570_2330: domain 1 of 1, from 227 to 286: score 40.0, E = 5.1e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ +
CP000570_2 227 DRALMLAGISHDLRTPLARLRLETEMSPSD----------------- 256

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + +++e+++r+i + d++r +
CP000570_2 257 ----------QVTKDAMVDDIEQMDRIIAAFIDYARPAQR 286

CP000570_0455: domain 1 of 1, from 432 to 494: score 34.4, E = 2.1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+a+r +++ + +++e+ ++
CP000570_0 432 ALGQMAAGITHELNQPLAALRSFSDNTRV--------LLDRGEQAAA 470

peLRledpeyreyletilreaerllrLindlLdl<-*
re le i +er+ ++ n+l +
CP000570_0 471 ----------RENLEAIAALTERMGKITNQLKLF 494

CP000570_0186: domain 1 of 1, from 201 to 270: score 27.1, E = 2.4e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ +a+++HE+ TPL++I +++e L+e a +t+++
CP000570_0 201 ALGVQAATVAHEMGTPLSTIAMLTEELRE------AARTDAGLAR-- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y l++++++ ++ + + +l+ + +
CP000570_0 240 ---------YDADLKVLEEQMSQCTSALARLRSRASERPS 270


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-15 1 0|=
-14 36 0|===
-13 85 2|*======
-12 270 90|======*==============
-11 413 468|================================ *
-10 655 868|=================================================== *
-9 729 897|========================================================= *
-8 666 671|===================================================*
-7 430 423|================================*=
-6 296 243|==================*====
-5 172 133|==========*===
-4 78 71|=====*
-3 53 37|==*==
-2 28 19|=*=
-1 9 10|*
0 7 5|*
1 1 2|*
2 3 1|*
3 0 0|
> 4 19 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 481.4476
P(chi-square) = 0

Total sequences searched: 3951

Whole sequence top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: