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Classification of phyla is from NCBI page
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2 accessions found for Burkholderia pseudomallei 1106a  

Data for CP000572  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000572.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000572_1509 CDS_1478146-1479456 92.0 9.7e-26 1
CP000572_2057 CDS_2073631-2070383 78.0 9.2e-22 1
CP000572_1247 CDS_1228963-1231944 66.0 2.2e-18 1
CP000572_0808 CDS_797997-796441 63.2 1.4e-17 1
CP000572_2656 CDS_2656829-2655687 61.8 3.6e-17 1
CP000572_4013 CDS_3982457-3983941 60.0 1.2e-16 1
CP000572_0847 CDS_832076-833392 56.0 1.6e-15 1
CP000572_1095 CDS_1081288-1082601 54.5 4.2e-15 1
CP000572_1625 CDS_1589717-1591798 52.5 1.6e-14 1
CP000572_0791 CDS_782649-780841 50.9 4.4e-14 1
CP000572_0041 CDS_38143-39522 49.7 9.6e-14 1
CP000572_2637 CDS_2631093-2633600 42.1 1.4e-11 1
CP000572_0166 CDS_157169-159577 41.3 2.3e-11 1
CP000572_2371 CDS_2361068-2362405 39.7 6.5e-11 1
CP000572_0475 CDS_443351-445384 34.4 2.1e-09 1
CP000572_0196 CDS_187363-188643 27.1 2.4e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000572_1509 1/1 206 272 .. 1 87 [] 92.0 9.7e-26
CP000572_2057 1/1 493 558 .. 1 87 [] 78.0 9.2e-22
CP000572_1247 1/1 677 748 .. 1 87 [] 66.0 2.2e-18
CP000572_0808 1/1 284 349 .. 1 87 [] 63.2 1.4e-17
CP000572_2656 1/1 152 220 .. 1 87 [] 61.8 3.6e-17
CP000572_4013 1/1 239 304 .. 1 87 [] 60.0 1.2e-16
CP000572_0847 1/1 213 278 .. 1 87 [] 56.0 1.6e-15
CP000572_1095 1/1 219 277 .. 1 87 [] 54.5 4.2e-15
CP000572_1625 1/1 84 149 .. 1 87 [] 52.5 1.6e-14
CP000572_0791 1/1 235 300 .. 1 87 [] 50.9 4.4e-14
CP000572_0041 1/1 238 304 .. 1 87 [] 49.7 9.6e-14
CP000572_2637 1/1 586 656 .. 1 87 [] 42.1 1.4e-11
CP000572_0166 1/1 540 612 .. 1 87 [] 41.3 2.3e-11
CP000572_2371 1/1 227 286 .. 1 87 [] 39.7 6.5e-11
CP000572_0475 1/1 432 494 .. 1 81 [. 34.4 2.1e-09
CP000572_0196 1/1 201 270 .. 1 87 [] 27.1 2.4e-07

Alignments of top-scoring domains:
CP000572_1509: domain 1 of 1, from 206 to 272: score 92.0, E = 9.7e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt+++g++e+++e +ls+++r
CP000572_1 206 MRRDFVANVSHELKTPLTVLSGFLETMRE---------LPLSDDER- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle ++++a r+++++ dlL l+++e +
CP000572_1 243 ----------ARYLELMEQQASRMRHIVTDLLVLAKLEGE 272

CP000572_2057: domain 1 of 1, from 493 to 558: score 78.0, E = 9.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak f+a++sHE+RTPL+++ g++el+ + ++l +eq
CP000572_2 493 AKVAFFASMSHEIRTPLSSLVGNIELIAR---------GPLAPEQ-- 528

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ++ +a+ l +++nd+Ld+s+i+ g
CP000572_2 529 ----------QARVKAMETSARGLMQIVNDVLDFSKIDVG 558

CP000572_1247: domain 1 of 1, from 677 to 748: score 66.0, E = 2.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPLtaI g++++L + + g t +++ r
CP000572_1 677 LRNSLLSAISHDLRTPLTAIVGLSSMLAN-----ARGATREGSPARE 718

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ i++ea r+ ++ +lLd++r++ag
CP000572_1 719 ----------DELVDAIHDEALRMTGIVTNLLDMARLQAG 748

CP000572_0808: domain 1 of 1, from 284 to 349: score 63.2, E = 1.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ae +l+ +e +++
CP000572_0 284 LQKRFIADAAHQMKTPLAGLRTQAEFALR---------HEVNADV-- 319

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ le i ++e+ rL+ +lL l+r+e+
CP000572_0 320 ----------ARSLEQIATSSEQAARLVTQLLALARAENR 349

CP000572_2656: domain 1 of 1, from 152 to 220: score 61.8, E = 3.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++nl+HE+++PL +Irg+a+lL+ el +e+ +++
CP000572_2 152 VNKQLIRNLAHEIKNPLGGIRGAAQLLEFEL-------GERERDEL- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey+++i++e++rl+ L+++lL+ r +
CP000572_2 191 ----------REYTQVIIKESDRLQTLVDRLLEPHRHPHI 220

CP000572_4013: domain 1 of 1, from 239 to 304: score 60.0, E = 1.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLtaI+++ae + +++++q+
CP000572_4 239 AQRKFIADAAHQLRTPLTAIKLHAEQAAV----------ARDPQQA- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++++a+r rL n+lL l+r+e g
CP000572_4 275 ----------LTAVRELRSAADRAVRLSNQLLSLARAEPG 304

CP000572_0847: domain 1 of 1, from 213 to 278: score 56.0, E = 1.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+a++ a+l + ++++ r
CP000572_0 213 TQKAFVADAAHELRTPLAAVQIQAQLVAR----------AQDDVSR- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re++ +++ + r rL ++lL l+r+e g
CP000572_0 249 ----------REAIVDLQSGVTRATRLAEQLLALARAEPG 278

CP000572_1095: domain 1 of 1, from 219 to 277: score 54.5, E = 4.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+LRTPL+ +r+ ae++ +
CP000572_1 219 DRAVMLAGVAHDLRTPLARMRLRAEMMDD------------------ 247

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + + r+++++ ++++++L ++ +a
CP000572_1 248 ----------ARLRDGVVRDVDSMTHIVDQFLVFAHGDAD 277

CP000572_1625: domain 1 of 1, from 84 to 149: score 52.5, E = 1.6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + la++sHELR P++++++++el + + l +eq
CP000572_1 84 ASRGSLATASHELRAPVNGMLALVELVRQ---------GLLAPEQ-- 119

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++++++l r +nd+Ld + ieag
CP000572_1 120 ----------QRLLGLVQDSGQSLARVLNDILDHASIEAG 149

CP000572_0791: domain 1 of 1, from 235 to 300: score 50.9, E = 4.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl ++sHELRTPL aI g +e+Ll+ ++se
CP000572_0 235 AKNAFLGMVSHELRTPLQAICGSIEVLLA---------RPQSEAN-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++a +l++++ dl d+ ++++
CP000572_0 271 ----------MKTIKRLQNSAASLEAQVKDLTDYIKLRST 300

CP000572_0041: domain 1 of 1, from 238 to 304: score 49.7, E = 9.6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++H+LRTP+++I + ++ ++ e ++ +
CP000572_0 238 TQRRFIADAAHQLRTPIAVIDTQIQCARQ---------RENGDAAL- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +++r+++r+ + + lL l+ +ea
CP000572_0 275 ----------AALLASMQRSSRRMADVTDKLLLLAHAEAA 304

CP000572_2637: domain 1 of 1, from 586 to 656: score 42.1, E = 1.4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL++PL+aI y++ l+ l +++ +s+e++
CP000572_2 586 TMGEMASSIAHELNQPLAAINNYCSGTLA-----LVKSGRASPETL- 626

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le+ ++a r ++ +++++ + ++
CP000572_2 627 ----------APALEKTAQQALRAGMIVKRIREFVKRSEP 656

CP000572_0166: domain 1 of 1, from 540 to 612: score 41.3, E = 2.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l +++ls ++ +
CP000572_0 540 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL------SDKLSQPD-A 579

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ L ++ ti +++ + r+++d++d++r
CP000572_0 580 DVL-------KRGATTIVNQVAAMKRMVDDFRDYARTPPA 612

CP000572_2371: domain 1 of 1, from 227 to 286: score 39.7, E = 6.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ +
CP000572_2 227 DRALMLAGISHDLRTPLARLRLETEMSPSD----------------- 256

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + +++e+++r+i + d++r +
CP000572_2 257 ----------QATKDAMVDDIEQMDRIIAAFIDYARPAQR 286

CP000572_0475: domain 1 of 1, from 432 to 494: score 34.4, E = 2.1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+a+r +++ + +++e+ ++
CP000572_0 432 ALGQMAAGITHELNQPLAALRSFSDNTRV--------LLDRGEQAAA 470

peLRledpeyreyletilreaerllrLindlLdl<-*
re le i +er+ ++ n+l +
CP000572_0 471 ----------RENLEAIAALTERMGKITNQLKLF 494

CP000572_0196: domain 1 of 1, from 201 to 270: score 27.1, E = 2.4e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ +a+++HE+ TPL++I +++e L+e a +t+++
CP000572_0 201 ALGVQAATVAHEMGTPLSTIAMLTEELRE------AARTDAGLAR-- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y l++++++ ++ + + +l+ + +
CP000572_0 240 ---------YDADLKVLEEQMSQCTSALARLRSRASERPS 270


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-15 1 0|=
-14 33 0|===
-13 94 3|*=======
-12 273 91|======*==============
-11 409 476|================================ *
-10 671 883|==================================================== *
-9 759 912|==========================================================*
-8 666 683|====================================================*
-7 439 430|=================================*
-6 300 247|==================*=====
-5 174 135|==========*===
-4 78 72|=====*
-3 54 38|==*==
-2 28 20|=*=
-1 10 10|*
0 7 5|*
1 1 2|*
2 3 1|*
3 0 0|
> 4 19 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 476.2594
P(chi-square) = 0

Total sequences searched: 4019

Whole sequence top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: