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Classification of phyla is from NCBI page
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106 projects found  

1 accessions found for Mycobacterium sp. JLS  

Data for CP000580  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000580.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000580_3902 CDS_4164373-4162775 86.3 5.8e-24 1
CP000580_0651 CDS_708091-709269 74.1 1.7e-20 1
CP000580_0339 CDS_374224-378396 73.9 1.9e-20 1
CP000580_4924 CDS_5214547-5213126 71.7 7.7e-20 1
CP000580_1371 CDS_1478322-1479980 71.3 1e-19 1
CP000580_0700 CDS_747790-746756 67.8 1e-18 1
CP000580_4559 CDS_4836423-4838933 62.8 2.6e-17 1
CP000580_4632 CDS_4917186-4915639 60.5 1.2e-16 1
CP000580_2976 CDS_3143220-3144575 53.5 1.1e-14 1
CP000580_2686 CDS_2833895-2835478 50.3 9e-14 1
CP000580_4480 CDS_4749023-4750180 50.1 1e-13 1
CP000580_4783 CDS_5080859-5082205 48.8 2.4e-13 1
CP000580_0156 CDS_164262-165599 46.1 1.4e-12 1
CP000580_4521 CDS_4792324-4793511 45.0 2.9e-12 1
CP000580_2902 CDS_3057076-3058215 42.7 1.3e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000580_3902 1/1 300 367 .. 1 87 [] 86.3 5.8e-24
CP000580_0651 1/1 158 224 .. 1 87 [] 74.1 1.7e-20
CP000580_0339 1/1 351 417 .. 1 87 [] 73.9 1.9e-20
CP000580_4924 1/1 245 309 .. 1 87 [] 71.7 7.7e-20
CP000580_1371 1/1 294 361 .. 1 87 [] 71.3 1e-19
CP000580_0700 1/1 112 178 .. 1 87 [] 67.8 1e-18
CP000580_4559 1/1 607 675 .. 1 87 [] 62.8 2.6e-17
CP000580_4632 1/1 240 312 .. 1 87 [] 60.5 1.2e-16
CP000580_2976 1/1 235 301 .. 1 87 [] 53.5 1.1e-14
CP000580_2686 1/1 288 356 .. 1 87 [] 50.3 9e-14
CP000580_4480 1/1 147 211 .. 1 87 [] 50.1 1e-13
CP000580_4783 1/1 231 297 .. 1 87 [] 48.8 2.4e-13
CP000580_0156 1/1 221 287 .. 1 87 [] 46.1 1.4e-12
CP000580_4521 1/1 156 220 .. 1 87 [] 45.0 2.9e-12
CP000580_2902 1/1 141 205 .. 1 87 [] 42.7 1.3e-11

Alignments of top-scoring domains:
CP000580_3902: domain 1 of 1, from 300 to 367: score 86.3, E = 5.8e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+aIrgy+el+++ ++++l+ +
CP000580_3 300 RVRQFVADASHELRTPLAAIRGYTELAQR-------HSDALPGDV-- 337

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++++e+ r+ rL++d+L l+r++ g
CP000580_3 338 ----------AHAMNRVESETARMTRLVEDMLLLARLDDG 367

CP000580_0651: domain 1 of 1, from 158 to 224: score 74.1, E = 1.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a+ ++ae+Ll+ ++ ++e++
CP000580_0 158 TRRDFVANVSHELKTPVGAMGLLAEALLA---------SADDPETV- 194

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ ++ +ea+rl ++i +l +lsr++ g
CP000580_0 195 ----------RRFAGKMVDEAHRLADMIGELIELSRLQGG 224

CP000580_0339: domain 1 of 1, from 351 to 417: score 73.9, E = 1.9e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ f++n+sHE+RTPLt I+g + +l+ +el+
CP000580_0 351 AKTTFFSNISHEFRTPLTLILGPLAEMLR--------TSELDVRV-- 387

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re le ++r + rl +L+n lLd+sri+ag
CP000580_0 388 ----------REELELAHRNGLRLAKLVNTLLDFSRIQAG 417

CP000580_4924: domain 1 of 1, from 245 to 309: score 71.7, E = 7.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ +++ e +
CP000580_4 245 RMRRFITDASHELRTPLTTIRGFAELYRQGA--------ARDVEML- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++i++e++r+ L++dlL l+r++a+
CP000580_4 283 -------------MNRIESESRRMGLLVEDLLLLARLDAQ 309

CP000580_1371: domain 1 of 1, from 294 to 361: score 71.3, E = 1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++++l++
CP000580_1 294 LQRRFTSDVSHELRTPLTTVRMAADLIHD-------HSDDLDPAL-- 331

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e + +e++r + L++dlL++sr +ag
CP000580_1 332 ----------RRSTELMVSELDRFETLLSDLLEISRHDAG 361

CP000580_0700: domain 1 of 1, from 112 to 178: score 67.8, E = 1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a +sH+LRTPL++Ir+ +e++ + + + +++
CP000580_0 112 SRRQLVAFVSHDLRTPLAGIRAVSEAIAD---------GLVGGDEV- 148

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + i++e+ rl+++++dl ++s+i ag
CP000580_0 149 ----------RAHAKHIEQESIRLSEMVDDLFEMSKINAG 178

CP000580_4559: domain 1 of 1, from 607 to 675: score 62.8, E = 2.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPL+a +++++ L+ + + s+++r
CP000580_4 607 LRRSLLSAVSHDLRTPLAAAKAAVSSLRS-------DEVDFSADDR- 645

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l t+++++++l +L+ +lLd sr+ ag
CP000580_4 646 ----------AELLATVEESVDQLTALVANLLDSSRLAAG 675

CP000580_4632: domain 1 of 1, from 240 to 312: score 60.5, E = 1.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++++++ HELRTPLt++r+++elL + + ++g + l+ee++
CP000580_4 240 RQARLVSDAGHELRTPLTSLRTNVELLMASQ---APGAPRLPEEEM- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ ++e l+ L+ dl dl+r eag
CP000580_4 283 ----------AGLRADVIAQIEELSTLVGDLVDLTRDEAG 312

CP000580_2976: domain 1 of 1, from 235 to 301: score 53.5, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a +sHELRTPLta+r+++e+L + ++++eqr
CP000580_2 235 SARDFAAVASHELRTPLTAMRTNLEVLST---------LDMTDEQR- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ + r r+++ + l l++ e
CP000580_2 272 ----------KEVINDVVRTQTRIEATLTALERLAQGELT 301

CP000580_2686: domain 1 of 1, from 288 to 356: score 50.3, E = 9e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL + +++lL++++ +++ +e
CP000580_2 288 ELEQFAYVASHDLQEPLRKVASFCQLLEKRY-------GDKLDERG- 326

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey++ + + a+r++ LindlL++sr +
CP000580_2 327 ----------VEYIKYAVDGAKRMQVLINDLLTFSRVGRL 356

CP000580_4480: domain 1 of 1, from 147 to 211: score 50.1, E = 1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a+l+HE+RTP++++++y+e++++++ l++++
CP000580_4 147 SRRQLFADLAHEIRTPVSVLQAYTEAIEDGV-------RSLTPDT-- 184

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++++++rl r +d+ l+++e+
CP000580_4 185 -------------TAMLRDQTQRLVRFAEDVAALAQAEES 211

CP000580_4783: domain 1 of 1, from 231 to 297: score 48.8, E = 2.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f++ +HELRTPLta+r+++e+L + +l +eqr
CP000580_4 231 SARDFASVSAHELRTPLTAMRTNLEVLAT---------LDLADEQR- 267

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ ++r r+++ ++ l l++ e
CP000580_4 268 ----------KEVINDVIRTQSRIEATLSALERLAQGELS 297

CP000580_0156: domain 1 of 1, from 221 to 287: score 46.1, E = 1.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+an++HELRTPLta+r+ +++L+ ++l+e++r
CP000580_0 221 AAQDFAANAAHELRTPLTAMRADLDTLRI---------HDLPEDER- 257

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + + r+ +r +++i l +l+ +
CP000580_0 258 ----------AEVVADLSRAQRRVEAIITALGQLASGQLA 287

CP000580_4521: domain 1 of 1, from 156 to 220: score 45.0, E = 2.9e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ +l+HE+RTP++++ +y+e+L++++ l++++
CP000580_4 156 TRQQLFGDLAHEIRTPVAVLEAYIEALEDGV-------RSLTPQT-- 193

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++rl r +d+ l+++e+
CP000580_4 194 -------------AAMLRDQTRRLVRFSDDVAALAKAEES 220

CP000580_2902: domain 1 of 1, from 141 to 205: score 42.7, E = 1.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++++l+HE+RTP++++ +y e++++++ l++e+
CP000580_2 141 TRRRLFSDLAHEIRTPVAVLEAYFEAIEDGV-------RSLTPET-- 178

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ rl r dl l+r+e+
CP000580_2 179 -------------AAMLRDQTGRLVRFAGDLGALARAEES 205


Histogram of all scores:
score obs exp (one = represents 20 sequences)
----- --- ---
-15 2 0|=
-14 11 0|=
-13 64 4|*===
-12 222 131|======*=====
-11 529 680|=========================== *
-10 977 1262|================================================= *
-9 1170 1303|==========================================================*
-8 1043 975|================================================*====
-7 717 614|==============================*=====
-6 405 353|=================*===
-5 261 194|=========*====
-4 155 103|=====*==
-3 65 54|==*=
-2 46 28|=*=
-1 25 15|*=
0 13 7|*
1 7 4|*
2 6 2|*
3 2 1|*
4 1 0|=
> 5 18 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 273.7458
P(chi-square) = 0

Total sequences searched: 5739

Whole sequence top hits:
tophits_s report:
Total hits: 15
Satisfying E cutoff: 15
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 15
Satisfying E cutoff: 15
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: