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Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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106 projects found  

1 accessions found for Mycobacterium tuberculosis H37Ra  

Data for CP000611  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000611.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000611_1058 CDS_1159263-1157734 86.2 4.2e-24 1
CP000611_3873 CDS_4219455-4218028 82.2 6e-23 1
CP000611_3351 CDS_3637396-3635693 74.9 7e-21 1
CP000611_0778 CDS_853702-855159 73.5 1.7e-20 1
CP000611_0500 CDS_580659-581891 72.4 3.5e-20 1
CP000611_1053 CDS_1152994-1150412 65.2 3.9e-18 1
CP000611_1006 CDS_1098816-1100330 60.6 7.7e-17 1
CP000611_0923 CDS_1007148-1005808 54.0 5.7e-15 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000611_1058 1/1 277 344 .. 1 87 [] 86.2 4.2e-24
CP000611_3873 1/1 246 312 .. 1 87 [] 82.2 6e-23
CP000611_3351 1/1 295 362 .. 1 87 [] 74.9 7e-21
CP000611_0778 1/1 249 313 .. 1 87 [] 73.5 1.7e-20
CP000611_0500 1/1 157 223 .. 1 87 [] 72.4 3.5e-20
CP000611_1053 1/1 632 700 .. 1 87 [] 65.2 3.9e-18
CP000611_1006 1/1 239 311 .. 1 87 [] 60.6 7.7e-17
CP000611_0923 1/1 230 296 .. 1 87 [] 54.0 5.7e-15

Alignments of top-scoring domains:
CP000611_1058: domain 1 of 1, from 277 to 344: score 86.2, E = 4.2e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPL+aI+gyael + ++ ++l++ +
CP000611_1 277 RMRQFITDASHELRTPLAAIQGYAELTRQDS-------SDLPPTT-- 314

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +i++ea+r+ L+++lL lsr+ +g
CP000611_1 315 ----------EYALARIESEARRMTLLVDELLLLSRLSEG 344

CP000611_3873: domain 1 of 1, from 246 to 312: score 82.2, E = 6e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++f+a++sHELRTPL+aIrgy+el ++ ++e +
CP000611_3 246 CVRQFVADASHELRTPLAAIRGYTELTQR---------IGDDPEAV- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++ +e+er+ rL++dlL l+r+++g
CP000611_3 283 ----------AHAMSRVASETERITRLVEDLLLLARLDSG 312

CP000611_3351: domain 1 of 1, from 295 to 362: score 74.9, E = 7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++++l++
CP000611_3 295 LQRRFTSDVSHELRTPLTTVRMAADLIYD-------HSADLDPTL-- 332

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e + +e++r + L+ndlL++sr +ag
CP000611_3 333 ----------RRSTELMVSELDRFETLLNDLLEISRHDAG 362

CP000611_0778: domain 1 of 1, from 249 to 313: score 73.5, E = 1.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ + ++
CP000611_0 249 RMRQFITDASHELRTPLTTIRGFAELYRQGA-----------ARDV- 283

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++i++ea r+ L++dlL l+r++a
CP000611_0 284 ----------GMLLSRIESEASRMGLLVDDLLLLARLDAH 313

CP000611_0500: domain 1 of 1, from 157 to 223: score 72.4, E = 3.5e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+an+sHEL+TP+ a+ ++ae+Ll+ ++ ++e++
CP000611_0 157 ARRDFVANVSHELKTPVGAMALLAEALLA---------SADDSETV- 193

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ e++l ea+rl +++ +l +lsr++
CP000611_0 194 ----------RRFAEKVLIEANRLGDMVAELIELSRLQGA 223

CP000611_1053: domain 1 of 1, from 632 to 700: score 65.2, E = 3.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPL+a + +++ L++ +d + s+e++
CP000611_1 632 LRRSLLSAVSHDLRTPLAAAKVAVSSLRT-------EDVAFSPEDT- 670

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l ti++++++l +L+ +lLd sr+ ag
CP000611_1 671 ----------AELLATIEESIDQLTALVANLLDSSRLAAG 700

CP000611_1006: domain 1 of 1, from 239 to 311: score 60.6, E = 7.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +++ ++ HELRTPLt++r+++elL + + ++g + l+ +++
CP000611_1 239 RQARLVTDAGHELRTPLTSLRTNVELLMASM---APGAPRLPKQEM- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +l ++e l+ L+ dl dlsr +ag
CP000611_1 282 ----------VDLRADVLAQIEELSTLVGDLVDLSRGDAG 311

CP000611_0923: domain 1 of 1, from 230 to 296: score 54.0, E = 5.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a sHELRTPLta+r+++e+L + +l+++qr
CP000611_0 230 SARDFAAVSSHELRTPLTAMRTNLEVLST---------LDLPDDQR- 266

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l+ ++r r+++ ++ l l++ e
CP000611_0 267 ----------KEVLNDVIRTQSRIEATLSALERLAQGELS 296


Histogram of all scores:
score obs exp (one = represents 14 sequences)
----- --- ---
-14 2 0|=
-13 44 3|*===
-12 174 92|======*======
-11 393 478|============================= *
-10 744 887|====================================================== *
-9 810 916|==========================================================*
-8 680 685|================================================*
-7 492 432|==============================*=====
-6 285 248|=================*===
-5 177 136|=========*===
-4 108 73|=====*==
-3 61 38|==*==
-2 28 20|=*
-1 9 10|*
0 9 5|*
1 2 2|*
2 3 1|*
3 2 0|=
4 1 0|=
5 0 0|
> 6 10 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 183.9240
P(chi-square) = 6.672e-33

Total sequences searched: 4034

Whole sequence top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: