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Classification of phyla is from NCBI page
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264 projects found  

6 accessions found for Klebsiella pneumoniae subsp. pneumoniae MGH 78578  

Data for CP000647  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000647.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000647_3068 CDS_3428200-3430950 96.8 5.2e-27 1
CP000647_0332 CDS_380770-382065 91.9 1.2e-25 1
CP000647_3452 CDS_3838120-3841362 82.7 5e-23 1
CP000647_2595 CDS_2902892-2900052 79.4 4.4e-22 1
CP000647_3588 CDS_3975534-3973195 78.8 6.2e-22 1
CP000647_0867 CDS_997024-998496 78.8 6.4e-22 1
CP000647_2830 CDS_3166769-3165330 76.9 2.2e-21 1
CP000647_4174 CDS_4621094-4619721 66.1 2.6e-18 1
CP000647_4773 CDS_5310158-5311582 65.2 4.7e-18 1
CP000647_4667 CDS_5194283-5195716 63.4 1.5e-17 1
CP000647_2487 CDS_2771741-2773219 63.0 1.9e-17 1
CP000647_4320 CDS_4794118-4795512 61.8 4.2e-17 1
CP000647_4132 CDS_4577725-4576676 60.3 1.1e-16 1
CP000647_3376 CDS_3766178-3767065 59.4 2e-16 1
CP000647_0696 CDS_801558-798871 59.2 2.3e-16 1
CP000647_3737 CDS_4120713-4119358 53.8 7.6e-15 1
CP000647_2479 CDS_2757286-2759220 48.5 2.4e-13 1
CP000647_0781 CDS_902355-901258 45.8 1.4e-12 1
CP000647_2034 CDS_2265206-2266267 44.2 4e-12 1
CP000647_1489 CDS_1690184-1688883 44.1 4.4e-12 1
CP000647_4421 CDS_4915352-4917637 41.0 3.3e-11 1
CP000647_1692 CDS_1903762-1901753 35.1 1.5e-09 1
CP000647_1776 CDS_1995688-1994345 32.9 6.4e-09 1
CP000647_1107 CDS_1292135-1290669 26.8 3.4e-07 2

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000647_3068 1/1 292 357 .. 1 87 [] 96.8 5.2e-27
CP000647_0332 1/1 203 269 .. 1 87 [] 91.9 1.2e-25
CP000647_3452 1/1 596 662 .. 1 87 [] 82.7 5e-23
CP000647_2595 1/1 467 532 .. 1 87 [] 79.4 4.4e-22
CP000647_3588 1/1 282 347 .. 1 87 [] 78.8 6.2e-22
CP000647_0867 1/1 268 336 .. 1 87 [] 78.8 6.4e-22
CP000647_2830 1/1 255 323 .. 1 87 [] 76.9 2.2e-21
CP000647_4174 1/1 238 300 .. 1 87 [] 66.1 2.6e-18
CP000647_4773 1/1 255 320 .. 1 87 [] 65.2 4.7e-18
CP000647_4667 1/1 258 324 .. 1 87 [] 63.4 1.5e-17
CP000647_2487 1/1 265 329 .. 1 87 [] 63.0 1.9e-17
CP000647_4320 1/1 241 307 .. 1 87 [] 61.8 4.2e-17
CP000647_4132 1/1 129 186 .. 1 79 [. 60.3 1.1e-16
CP000647_3376 1/1 82 148 .. 1 87 [] 59.4 2e-16
CP000647_0696 1/1 663 730 .. 1 87 [] 59.2 2.3e-16
CP000647_3737 1/1 233 293 .. 1 87 [] 53.8 7.6e-15
CP000647_2479 1/1 424 489 .. 1 87 [] 48.5 2.4e-13
CP000647_0781 1/1 143 203 .. 1 87 [] 45.8 1.4e-12
CP000647_2034 1/1 136 200 .. 1 87 [] 44.2 4e-12
CP000647_1489 1/1 211 271 .. 1 87 [] 44.1 4.4e-12
CP000647_4421 1/1 402 464 .. 1 87 [] 41.0 3.3e-11
CP000647_1692 1/1 448 516 .. 1 87 [] 35.1 1.5e-09
CP000647_1776 1/1 226 284 .. 1 87 [] 32.9 6.4e-09

Alignments of top-scoring domains:
CP000647_3068: domain 1 of 1, from 292 to 357: score 96.8, E = 5.2e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ t+l++ q
CP000647_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TDLNATQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l ti+r+a+ ll++ind+Ld+s++eag
CP000647_3 328 ----------RDHLTTIERSANNLLAIINDVLDFSKLEAG 357

CP000647_0332: domain 1 of 1, from 203 to 269: score 91.9, E = 1.2e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e+++e + l +r
CP000647_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMQE---------QVLEGATR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+lsriea
CP000647_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSRIEAA 269

CP000647_3452: domain 1 of 1, from 596 to 662: score 82.7, E = 5e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHELRTP++aI g++elL + +el+ qr
CP000647_3 596 AKSRFLASMSHELRTPVSAIVGFLELLAK---------PELNVGQR- 632

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e + + a+ ll Li ++Ld+ +ie+g
CP000647_3 633 ----------KEAIELAGSTAQTLLGLIGNILDIDKIESG 662

CP000647_2595: domain 1 of 1, from 467 to 532: score 79.4, E = 4.4e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ +l+
CP000647_2 467 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KALPKGV-- 502

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP000647_2 503 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 532

CP000647_3588: domain 1 of 1, from 282 to 347: score 78.8, E = 6.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP000647_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTSEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP000647_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP000647_0867: domain 1 of 1, from 268 to 336: score 78.8, E = 6.4e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef+an+sH+LRTPLt+++gy+e+L +d+ l++e+r
CP000647_0 268 QRREFVANISHDLRTPLTSLLGYLETLTL-------KDEWLTAEER- 306

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+yl ++lr+++ ++L ++l +l+r+e+g
CP000647_0 307 ----------RQYLTIALRQGNKVRHLSQQLFELARLEHG 336

CP000647_2830: domain 1 of 1, from 255 to 323: score 76.9, E = 2.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP000647_2 255 QRHQFLRHLSHELKTPLASMREGTELLADRVA------GPLTPEQ-- 293

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e+++++++ l++Li++lLd+ r +a
CP000647_2 294 ----------QEIVEILDSSSRNLQKLIEQLLDYNRKQAD 323

CP000647_4174: domain 1 of 1, from 238 to 300: score 66.1, E = 2.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP000647_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr +a
CP000647_4 274 -------------LERIETEAHRLDSMINDLLVMSRNQAK 300

CP000647_4773: domain 1 of 1, from 255 to 320: score 65.2, E = 4.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + + +l HEL+ PL+aIrg+ae+L+e ++ +e
CP000647_4 255 AIENYVYDLTHELKSPLAAIRGAAEILRE---------GPPPEVA-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r++ L+++lL+ +r+e+
CP000647_4 291 ----------ARFTDNILAQNTRMQLLVERLLQQARLESR 320

CP000647_4667: domain 1 of 1, from 258 to 324: score 63.4, E = 1.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t + + +e++l + +s++++
CP000647_4 258 RQSNFSADIAHEIRTPITNLVTQTEIALS---------QSRSPQEL- 294

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l + l+e r++r+++d+L l++++++
CP000647_4 295 ----------EEVLYSNLEEFSRMSRMVSDMLFLAQADNN 324

CP000647_2487: domain 1 of 1, from 265 to 329: score 63.0, E = 1.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a++sHELRTPL+++rg +e++++++ ++e
CP000647_2 265 MRRDLMADISHELRTPLAVLRGELEAIQDGV-------RRFTPES-- 302

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP000647_2 303 -------------IPSLQAEVATLTKLVDDLHQLSMSDEG 329

CP000647_4320: domain 1 of 1, from 241 to 307: score 61.8, E = 4.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +t+ + e
CP000647_4 241 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RTPPGGES-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l r +
CP000647_4 278 ----------HQLAQVMAKEADRLNRVVSELLELVRPAHL 307

CP000647_4132: domain 1 of 1, from 129 to 186: score 60.3, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP000647_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP000647_4 165 ----------TEYTKVIIEQADRLRNLVDRLL 186

CP000647_3376: domain 1 of 1, from 82 to 148: score 59.4, E = 2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PL+a++ +e+++ + ++e r
CP000647_3 82 RERRFTSDAAHELRSPLAALKVQTEVAQL---------SLDDPEGR- 118

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ +++ ++r rL+++lL+lsr+++
CP000647_3 119 ----------EKALDQLHQGIDRATRLVDQLLTLSRLDSL 148

CP000647_0696: domain 1 of 1, from 663 to 730: score 59.2, E = 2.3e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CP000647_0 663 LRNSLLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSKH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i++ + rL+n+lLd++ri++g
CP000647_0 701 ----------APQANEIRQHVLNTTRLVNNLLDMARIQSG 730

CP000647_3737: domain 1 of 1, from 233 to 293: score 53.8, E = 7.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP000647_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMGE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP000647_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP000647_2479: domain 1 of 1, from 424 to 489: score 48.5, E = 2.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +++HE+RTPL++I++++e L+ +++s q
CP000647_2 424 HQRQFMGMVAHEFRTPLAVIQAALENLRL---------SAASTSQ-- 459

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++i r+a rl +L ++ L +r+ +
CP000647_2 460 ----------EARFDRIGRAATRLVQLTDNCLADARLASH 489

CP000647_0781: domain 1 of 1, from 143 to 203: score 45.8, E = 1.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL+++r+++elL + + ++
CP000647_0 143 RERLFTADVAHELRTPLAGLRLHLELLAK--------VHGMG----- 176

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +++ ++++ i++lL+l+r ++
CP000647_0 177 -------------VDPLIQRLDQMTTSISQLLQLARVGQS 203

CP000647_2034: domain 1 of 1, from 136 to 200: score 44.2, E = 4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ + a+++HELRTP+t +rg ++ L + + +e
CP000647_2 136 QRNLWNAAIAHELRTPVTILRGRLQGLVD---------GVFEPEP-- 171

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +l+++e l +Li+dl+ s +
CP000647_2 172 -----------SLFRNLLKQTEGLTNLIEDLRVVSSSGGA 200

CP000647_1489: domain 1 of 1, from 211 to 271: score 44.1, E = 4.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ ++ lse +
CP000647_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSEN-----------LSEAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP000647_1 245 -------------SQALNRDIGQLEALIEELLTYARLDRP 271

CP000647_4421: domain 1 of 1, from 402 to 464: score 41.0, E = 3.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + ++++++
CP000647_4 402 AVGQLTGGLAHDFNNLLAVIIGSLELVEP---------DARDAPR-- 437

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++l++aer L ++lL +sr +a
CP000647_4 438 -------------LSRALKAAERGALLTQRLLAFSRKQAL 464

CP000647_1692: domain 1 of 1, from 448 to 516: score 35.1, E = 1.5e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l+HE+++PL+a+++y+ ++ + a+++ + e+
CP000647_1 448 VVGQTMTTLAHEINQPLNALSMYLFTAGR------AIEQGQAEQA-- 486

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l++++ ++r++++i+ l++++r +
CP000647_1 487 ----------RTTLSKAEGLINRIDAIIRSLRQFTRRAEL 516

CP000647_1776: domain 1 of 1, from 226 to 284: score 32.9, E = 6.4e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + la++sH+L TP+t +++ +e++
CP000647_1 226 ERARILAAISHDLQTPITRMKLRVEMADQ------------------ 254

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ +++l++++ + rL+++ ++r ++
CP000647_1 255 ----------PELRDKLLQDLDNMTRLVREGIAFARTSQP 284


Histogram of all scores:
score obs exp (one = represents 16 sequences)
----- --- ---
-15 3 0|=
-14 9 0|=
-13 53 3|*===
-12 186 109|======*=====
-11 409 566|========================== *
-10 800 1050|================================================== *
-9 934 1084|==========================================================*
-8 856 812|==================================================*===
-7 605 511|===============================*======
-6 409 294|==================*=======
-5 216 161|==========*===
-4 110 86|=====*=
-3 64 45|==*=
-2 43 23|=*=
-1 29 12|*=
0 10 6|*
1 5 3|*
2 6 1|*
3 3 0|=
> 4 26 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 312.8544
P(chi-square) = 0

Total sequences searched: 4776

Whole sequence top hits:
tophits_s report:
Total hits: 24
Satisfying E cutoff: 24
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 23
Satisfying E cutoff: 23
Total memory: 30K


Acknowledgements:

This research is funded by:

Developed by: