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Classification of phyla is from NCBI page
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264 projects found  

2 accessions found for Enterobacter sp. 638  

Data for CP000653  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000653.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000653_3212 CDS_3527631-3530387 98.7 1.2e-27 1
CP000653_0862 CDS_966497-967792 91.8 1.2e-25 1
CP000653_2773 CDS_3030330-3027481 81.3 1.1e-22 1
CP000653_3612 CDS_3946769-3944436 78.8 5.4e-22 1
CP000653_1366 CDS_1504737-1506209 78.4 7.1e-22 1
CP000653_3015 CDS_3309461-3308028 71.5 6.3e-20 1
CP000653_2664 CDS_2900530-2901933 66.7 1.4e-18 1
CP000653_1198 CDS_1331284-1328597 59.8 1.3e-16 1
CP000653_4026 CDS_4415163-4416536 59.7 1.4e-16 1
CP000653_4061 CDS_4453296-4454345 59.2 2e-16 1
CP000653_3399 CDS_3735543-3736889 58.2 3.9e-16 1
CP000653_1849 CDS_2020287-2021675 56.9 9.1e-16 1
CP000653_0557 CDS_627633-629057 56.3 1.3e-15 1
CP000653_3782 CDS_4117176-4115830 54.9 3.3e-15 1
CP000653_3585 CDS_3924082-3925125 54.3 4.7e-15 1
CP000653_1488 CDS_1653793-1654869 45.9 1.2e-12 2
CP000653_1829 CDS_2000057-1998759 41.8 1.7e-11 1
CP000653_0289 CDS_340002-342278 36.2 6.5e-10 2

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000653_3212 1/1 292 357 .. 1 87 [] 98.7 1.2e-27
CP000653_0862 1/1 203 269 .. 1 87 [] 91.8 1.2e-25
CP000653_2773 1/1 469 534 .. 1 87 [] 81.3 1.1e-22
CP000653_3612 1/1 282 347 .. 1 87 [] 78.8 5.4e-22
CP000653_1366 1/1 268 336 .. 1 87 [] 78.4 7.1e-22
CP000653_3015 1/1 249 317 .. 1 87 [] 71.5 6.3e-20
CP000653_2664 1/1 240 304 .. 1 87 [] 66.7 1.4e-18
CP000653_1198 1/1 663 730 .. 1 87 [] 59.8 1.3e-16
CP000653_4026 1/1 238 300 .. 1 87 [] 59.7 1.4e-16
CP000653_4061 1/1 129 186 .. 1 79 [. 59.2 2e-16
CP000653_3399 1/1 236 302 .. 1 87 [] 58.2 3.9e-16
CP000653_1849 1/1 242 307 .. 1 87 [] 56.9 9.1e-16
CP000653_0557 1/1 255 320 .. 1 87 [] 56.3 1.3e-15
CP000653_3782 1/1 233 293 .. 1 87 [] 54.9 3.3e-15
CP000653_3585 1/1 136 196 .. 1 87 [] 54.3 4.7e-15
CP000653_1488 2/2 136 200 .. 1 87 [] 42.9 8.3e-12
CP000653_1829 1/1 211 271 .. 1 87 [] 41.8 1.7e-11
CP000653_0289 2/2 398 460 .. 1 87 [] 35.7 9.3e-10

Alignments of top-scoring domains:
CP000653_3212: domain 1 of 1, from 292 to 357: score 98.7, E = 1.2e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ +el++ q
CP000653_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------SELNPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP000653_3 328 ----------RDHLHTIERSANNLLAIINDVLDFSKLEAG 357

CP000653_0862: domain 1 of 1, from 203 to 269: score 91.8, E = 1.2e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e+++e ++l r
CP000653_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMQE---------QTLEGAPR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CP000653_0 240 ----------EKALHTMREQTHRMEGLVKQLLTLSKIEAA 269

CP000653_2773: domain 1 of 1, from 469 to 534: score 81.3, E = 1.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP000653_2 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ + +++ ll++i+d+Ld+s+ie++
CP000653_2 505 ----------ERLVTAMNNSSSLLLKIISDILDFSKIESE 534

CP000653_3612: domain 1 of 1, from 282 to 347: score 78.8, E = 5.4e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP000653_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTSEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP000653_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP000653_1366: domain 1 of 1, from 268 to 336: score 78.4, E = 7.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef+an+sH+LRTPLt+++gy+e+L +++ ++l++e+
CP000653_1 268 QRREFIANISHDLRTPLTSLLGYLETLSMKS-------ATLTAEES- 306

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl t+lr+++ ++L ++l +l+r+e g
CP000653_1 307 ----------QKYLATALRQGQKVRHLSQQLFELARLEYG 336

CP000653_3015: domain 1 of 1, from 249 to 317: score 71.5, E = 6.3e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl+++sHEL+TPL+++r +elL +e+ ++l++eq
CP000653_3 249 QRHQFLRHISHELKTPLASMREGTELLADEVA------GPLTAEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e+++ +++ l++Li++lLd+ r a
CP000653_3 288 ----------KEIVEILDASSRNLQKLIEQLLDYNRKLAD 317

CP000653_2664: domain 1 of 1, from 240 to 304: score 66.7, E = 1.4e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ ++e
CP000653_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RQFTPES-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L+ndl +ls ++g
CP000653_2 278 -------------VTSLQAEVGTLTKLVNDLHQLSMSDEG 304

CP000653_1198: domain 1 of 1, from 663 to 730: score 59.8, E = 1.3e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l ++ ++++
CP000653_1 663 IRNSLLAALSHDLRTPLTVLFGQAEILTLDL-------AAENSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i++ + rL+n+lLd++ri++g
CP000653_1 701 ----------APQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CP000653_4026: domain 1 of 1, from 238 to 300: score 59.7, E = 1.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP000653_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP000653_4 274 -------------LERIEMEAHRLDSMINDLLVMSRNQQK 300

CP000653_4061: domain 1 of 1, from 129 to 186: score 59.2, E = 2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP000653_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLTK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
+ey+++i+++a+rl++L+++lL
CP000653_4 165 ----------AEYTNVIIEQADRLRNLVDRLL 186

CP000653_3399: domain 1 of 1, from 236 to 302: score 58.2, E = 3.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ + + ++ q
CP000653_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL--------SLDDPAAQ-- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l ++ ++r +rL+++lL+lsr+++
CP000653_3 273 ----------EKALAQLHTGIDRASRLVDQLLTLSRLDSL 302

CP000653_1849: domain 1 of 1, from 242 to 307: score 56.9, E = 9.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL+a+r ++e+L+ se q
CP000653_1 242 RERIFIADAAHELRTPLAAMRINVEALQS---------YISSESQ-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l i+r+ r rL+n+lL l ea
CP000653_1 278 ----------QELLAGIIRSNSRAARLVNQLLLLMHSEAR 307

CP000653_0557: domain 1 of 1, from 255 to 320: score 56.3, E = 1.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + +l HEL+ PL+aIrg ae+L e ++ +
CP000653_0 255 YIEHYVHALTHELKSPLAAIRGSAEILAE---------QPPPQVA-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL+ +r+e+
CP000653_0 291 ----------ARFVDNILVQNARMQSLVEKLLEQARLENR 320

CP000653_3782: domain 1 of 1, from 233 to 293: score 54.9, E = 3.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e e+
CP000653_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMGE--------------ED-- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP000653_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP000653_3585: domain 1 of 1, from 136 to 196: score 54.3, E = 4.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL++Ir+++el+ +
CP000653_3 136 QERLFTADAAHELRTPLAGIRLHLELMAQSG---------------- 166

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+t+++ +++l + +++lL l+r+++
CP000653_3 167 ----------TPQASTLIDRIDQLMHTVEQLLMLARAGQA 196

CP000653_1488: domain 2 of 2, from 136 to 200: score 42.9, E = 8.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ + a+++HELRTP+t +rg ++ L + + ++
CP000653_1 136 QRNLWNAAIAHELRTPVTILRGRLQGLVD---------GVFEPDP-- 171

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +l+++e l +Li+dl+ s +
CP000653_1 172 -----------ALFRNLLKQTEGLTNLIEDLRVVSSSGGA 200

CP000653_1829: domain 1 of 1, from 211 to 271: score 41.8, E = 1.7e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k ++ +++HELRTPL +r +e+ ++ l++ +
CP000653_1 211 SKKALIDGIAHELRTPLVRLRYRLEMSEN-----------LTAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l + r++ +l++Li++lL+++r++ +
CP000653_1 245 -------------LVALNRDIGQLEALIEELLTYARLDRP 271

CP000653_0289: domain 2 of 2, from 398 to 460: score 35.7, E = 9.3e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el+ + +++
CP000653_0 398 AVGQLTGGLAHDFNNLLAVIIGSLELANP---------DSPDAPR-- 433

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++l++aer L ++lL +sr ++
CP000653_0 434 -------------ITRALKAAERGALLTQRLLAFSRKQSL 460


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-14 6 0|=
-13 37 3|*==
-12 170 94|=======*======
-11 402 487|=============================== *
-10 723 904|======================================================== *
-9 765 934|==========================================================*
-8 700 699|=====================================================*
-7 538 440|=================================*========
-6 323 253|===================*=====
-5 176 139|==========*===
-4 115 74|=====*===
-3 58 39|==*==
-2 30 20|=*=
-1 27 10|*==
0 9 5|*
1 6 2|*
2 5 1|*
3 3 0|=
4 2 0|=
> 5 20 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 255.1632
P(chi-square) = 0

Total sequences searched: 4115

Whole sequence top hits:
tophits_s report:
Total hits: 18
Satisfying E cutoff: 18
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 18
Satisfying E cutoff: 18
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: