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4 accessions found for Mycobacterium gilvum PYR-GCK  

Data for CP000656  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000656.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000656_0987 CDS_1046914-1050399 88.3 1.4e-24 1
CP000656_2249 CDS_2355541-2357181 87.1 3.2e-24 1
CP000656_0036 CDS_32638-33660 74.9 9e-21 1
CP000656_1568 CDS_1654644-1656251 71.1 1.1e-19 1
CP000656_4683 CDS_5021549-5019894 68.0 8.3e-19 1
CP000656_0083 CDS_74374-73166 63.5 1.5e-17 1
CP000656_1872 CDS_1967608-1969056 62.8 2.3e-17 1
CP000656_4396 CDS_4708609-4704524 59.5 2.1e-16 1
CP000656_4216 CDS_4504780-4503416 54.5 5.4e-15 1
CP000656_3250 CDS_3459539-3461128 48.1 3.4e-13 1
CP000656_2818 CDS_2998028-2996844 45.9 1.5e-12 1
CP000656_0458 CDS_485882-484539 45.7 1.6e-12 1
CP000656_0880 CDS_937677-936493 45.4 2e-12 1
CP000656_3863 CDS_4152679-4153821 44.8 3.1e-12 1
CP000656_1727 CDS_1811368-1810025 41.5 2.7e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000656_0987 1/1 479 546 .. 1 87 [] 88.3 1.4e-24
CP000656_2249 1/1 315 382 .. 1 87 [] 87.1 3.2e-24
CP000656_0036 1/1 112 178 .. 1 87 [] 74.9 9e-21
CP000656_1568 1/1 268 332 .. 1 87 [] 71.1 1.1e-19
CP000656_4683 1/1 291 362 .. 1 87 [] 68.0 8.3e-19
CP000656_0083 1/1 158 224 .. 1 87 [] 63.5 1.5e-17
CP000656_1872 1/1 246 318 .. 1 87 [] 62.8 2.3e-17
CP000656_4396 1/1 321 387 .. 1 87 [] 59.5 2.1e-16
CP000656_4216 1/1 236 302 .. 1 87 [] 54.5 5.4e-15
CP000656_3250 1/1 289 357 .. 1 87 [] 48.1 3.4e-13
CP000656_2818 1/1 156 220 .. 1 87 [] 45.9 1.5e-12
CP000656_0458 1/1 222 288 .. 1 87 [] 45.7 1.6e-12
CP000656_0880 1/1 156 220 .. 1 87 [] 45.4 2e-12
CP000656_3863 1/1 156 220 .. 1 87 [] 44.8 3.1e-12
CP000656_1727 1/1 231 297 .. 1 87 [] 41.5 2.7e-11

Alignments of top-scoring domains:
CP000656_0987: domain 1 of 1, from 479 to 546: score 88.3, E = 1.4e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++I+ +a lL e +d++l+++q
CP000656_0 479 YKSEFLANMSHELRTPLNSILILAGLLTE-------SDEPLNAKQ-- 516

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ eti+++++ ll+Li+++Ldl++ e+g
CP000656_0 517 ----------HEFAETIQQSGKDLLNLIDEVLDLAKVESG 546

CP000656_2249: domain 1 of 1, from 315 to 382: score 87.1, E = 3.2e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+aIrgy+el+++++ +el+++
CP000656_2 315 RVRQFVADASHELRTPLAAIRGYTELAQRKQ-------AELPDDV-- 352

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++++e+ r+ +L++d+L l+r+++g
CP000656_2 353 ----------AHAMSRVESETARMTQLVEDMLLLARLDTG 382

CP000656_0036: domain 1 of 1, from 112 to 178: score 74.9, E = 9e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a +sH+LRTPL++Ir+ ae++ + + ++e++
CP000656_0 112 SRRRLVAFVSHDLRTPLAGIRAVAEAIAD---------GVVPDEEV- 148

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + i++e+ rl+++++dl ++s+i ag
CP000656_0 149 ----------RVHAKHIENESIRLSEMVDDLFEMSKINAG 178

CP000656_1568: domain 1 of 1, from 268 to 332: score 71.1, E = 1.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ +++ e +
CP000656_1 268 RMRRFITDASHELRTPLTTIRGFAELYRQGA--------ARDVEML- 305

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+i++e++r+ L++dlL l+r++a+
CP000656_1 306 -------------MGRIKSESRRMGLLVEDLLLLARLDAQ 332

CP000656_4683: domain 1 of 1, from 291 to 362: score 68.0, E = 8.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + + s++++
CP000656_4 291 LQRRFTSDVSHELRTPLTTVRMAADLIHD--------HIHDSPDDLD 329

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
p+L r+ +e + +e++r ++L+ndlL++sr +ag
CP000656_4 330 PAL-------RRSTELMVNELDRFESLLNDLLEISRHDAG 362

CP000656_0083: domain 1 of 1, from 158 to 224: score 63.5, E = 1.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a+ +ae+ l+ + +++++
CP000656_0 158 TRRDFVANVSHELKTPVGALGVLAEAVLA---------SVEDPDTV- 194

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + e++ ea+rl +++ +l +lsr++ g
CP000656_0 195 ----------RHFAEKMVTEADRLANMVGELIELSRLQGG 224

CP000656_1872: domain 1 of 1, from 246 to 318: score 62.8, E = 2.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+++a++ HELRTPLt++r+++elL + +g + +ee++
CP000656_1 246 RQSRLVADAGHELRTPLTSLRTNVELLMSSMK---PGAPRIPEEDM- 288

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + ++ ++e l+ L+ dl dl+r eag
CP000656_1 289 ----------DDLRSDVIGQIEELSTLVGDLVDLTRDEAG 318

CP000656_4396: domain 1 of 1, from 321 to 387: score 59.5, E = 2.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ f++n+sHE+RTPLt I+ ++ L++ ++l++
CP000656_4 321 AKTTFFSNISHEFRTPLTLILDPVSELRR--------ADTLGDAA-- 357

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+++ r + rl++L+n lLd+srieag
CP000656_4 358 ----------RQELDVVWRNGLRLNKLVNTLLDFSRIEAG 387

CP000656_4216: domain 1 of 1, from 236 to 302: score 54.5, E = 5.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a +sHELRTPLta+r+++e+L + +l++eqr
CP000656_4 236 SARDFAAVASHELRTPLTAMRTNLEVLAT---------LDLGAEQR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l ++r r+++ + l l++ e
CP000656_4 273 ----------QEVLGDVIRTQSRIEATLTALERLAQGELT 302

CP000656_3250: domain 1 of 1, from 289 to 357: score 48.1, E = 3.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL + +++lL++++ +++ +e
CP000656_3 289 ELEQFAYVASHDLQEPLRKVASFCQLLEKRY-------GDQLDERG- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ey+ + + a+r++ LindlL++sr +
CP000656_3 328 ----------KEYIGFAVDGAKRMQVLINDLLTFSRVGRL 357

CP000656_2818: domain 1 of 1, from 156 to 220: score 45.9, E = 1.5e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ +l+HE+RTP++++ +y+e+L++++ +l++++
CP000656_2 156 TRQQLFGDLAHEIRTPVAVLEAYIEALEDGV-------RTLTPQT-- 193

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++rl r nd+ l+++e+
CP000656_2 194 -------------ATMLRDQTRRLVRFSNDVAALAKAEES 220

CP000656_0458: domain 1 of 1, from 222 to 288: score 45.7, E = 1.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+an++HELRTPLta+r+ +++L+ ++l++e+r
CP000656_0 222 AAQDFAANAAHELRTPLTAMRADLDTLRI---------HNLPDEER- 258

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e + + r+ +r + +i l +l+ +
CP000656_0 259 ----------DEVVADLARAQRRVEGIITALGQLASGQLA 288

CP000656_0880: domain 1 of 1, from 156 to 220: score 45.4, E = 2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ +l+HE+RTP++++ +y+e+L++++ +l++++
CP000656_0 156 TRQRLFGDLAHEIRTPVAVLEAYIEALEDGV-------RTLTPQT-- 193

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++++rl r +d+ l+++e+
CP000656_0 194 -------------AAMLRDQTRRLVRFSDDVAALAKAEES 220

CP000656_3863: domain 1 of 1, from 156 to 220: score 44.8, E = 3.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ +l+HE+RTP++++ +y+e+L++++ +l++++
CP000656_3 156 TRRRLFGDLAHEIRTPVAVLDAYVEALEDGV-------RTLNPDT-- 193

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++++++ rl r d+ l+++e+
CP000656_3 194 -------------VAVLRDQTGRLVRFSGDVAALAKAEES 220

CP000656_1727: domain 1 of 1, from 231 to 297: score 41.5, E = 2.7e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f++ +HELRTPLta+r+++e+L + else+ r
CP000656_1 231 SARDFASVSAHELRTPLTAMRTNLEVLAT---------LELSEDGR- 267

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e l + r r+++ + l l++ e
CP000656_1 268 ----------NEVLGDVMRTQTRIEATLGALERLAQGELS 297


Histogram of all scores:
score obs exp (one = represents 19 sequences)
----- --- ---
-15 1 0|=
-14 12 0|=
-13 45 3|*==
-12 209 119|======*====
-11 481 621|========================== *
-10 893 1152|=============================================== *
-9 1078 1190|========================================================= *
-8 945 891|==============================================*===
-7 666 561|=============================*======
-6 392 323|================*====
-5 235 177|=========*===
-4 138 94|====*===
-3 44 50|==*
-2 37 26|=*
-1 23 13|*=
0 11 7|*
1 5 3|*
2 5 1|*
3 3 1|*
4 1 0|=
5 1 0|=
6 0 0|
7 0 0|
> 8 16 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 256.1921
P(chi-square) = 0

Total sequences searched: 5241

Whole sequence top hits:
tophits_s report:
Total hits: 15
Satisfying E cutoff: 15
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 15
Satisfying E cutoff: 15
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: