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Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

1 accessions found for Legionella pneumophila str. Corby  

Data for CP000675  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000675.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000675_1537 CDS_1743113-1740663 99.2 7e-28 2
CP000675_1320 CDS_1489574-1492306 99.0 8.1e-28 1
CP000675_1579 CDS_1829717-1831747 70.8 7.8e-20 1
CP000675_0621 CDS_685554-687140 60.1 8.7e-17 1
CP000675_0693 CDS_764773-763358 56.6 8.2e-16 1
CP000675_0829 CDS_918552-917185 52.0 1.7e-14 1
CP000675_1168 CDS_1315767-1314745 47.4 3.4e-13 1
CP000675_2494 CDS_2804476-2805573 45.9 9.1e-13 1
CP000675_1948 CDS_2226232-2227509 35.7 7e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000675_1320 1/1 297 362 .. 1 87 [] 99.0 8.1e-28
CP000675_1537 1/2 194 260 .. 1 87 [] 71.0 7e-20
CP000675_1579 1/1 280 338 .. 1 80 [. 70.8 7.8e-20
CP000675_0621 1/1 310 376 .. 1 87 [] 60.1 8.7e-17
CP000675_0693 1/1 246 311 .. 1 87 [] 56.6 8.2e-16
CP000675_0829 1/1 231 295 .. 1 87 [] 52.0 1.7e-14
CP000675_1168 1/1 123 189 .. 1 87 [] 47.4 3.4e-13
CP000675_2494 1/1 138 204 .. 1 87 [] 45.9 9.1e-13
CP000675_1948 1/1 205 273 .. 1 87 [] 35.7 7e-10
CP000675_1537 2/2 592 660 .. 1 87 [] 28.2 9.2e-08

Alignments of top-scoring domains:
CP000675_1320: domain 1 of 1, from 297 to 362: score 99.0, E = 8.1e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ksef+an+sHE+RTP+++++g++ +Lle ++l++ q
CP000675_1 297 QKSEFIANMSHEIRTPMNGVIGFTNVLLE---------SKLDPLQ-- 332

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y++ti+++a+ ll++ind+Ld+s+i+ag
CP000675_1 333 ----------LDYVKTIKSSAQDLLSIINDILDFSKIDAG 362

CP000675_1537: domain 1 of 2, from 194 to 260: score 71.0, E = 7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f+an+sHELRTPL I+g +e+Ll+ + l++
CP000675_1 194 IKTQFFANVSHELRTPLMLILGSLEMLLA--------EKRLPSFV-- 230

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l++i++ a+ ll+ +ndlL +s+++ag
CP000675_1 231 ----------LNTLRRIQNNAQILLKHVNDLLNISKLDAG 260

CP000675_1579: domain 1 of 1, from 280 to 338: score 70.8, E = 7.8e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ f+an+sH++RTPLt+++g++elL++ t +++eq
CP000675_1 280 AKTAFIANMSHDIRTPLTGVIGMSELLEN---------TVKDPEQ-- 315

peLRledpeyreyletilreaerllrLindlLd<-*
+e + +++++e ll+++nd+Ld
CP000675_1 316 ----------KEEAHMLHDSGEELLNMLNDILD 338

CP000675_0621: domain 1 of 1, from 310 to 376: score 60.1, E = 8.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f a+++HELR+PL aI +++l ++ ++l+ee
CP000675_0 310 ALGRFSASIAHELRNPLGAIAHAIQLFGDN--------EDLNEEN-- 346

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i + er++r i ++L+lsr e
CP000675_0 347 ----------TRLKQLIMNNCERMNRVIKNVLQLSRREKS 376

CP000675_0693: domain 1 of 1, from 246 to 311: score 56.6, E = 8.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++HELRTPL+a+++ a+++l+ ++ ee+
CP000675_0 246 REKRFAADAAHELRTPLAALKAQAQVALN---------SNDIEEK-- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++++ +++r +++++lL++s++ +
CP000675_0 282 ----------NQALQKLIASVNRSTHIVQQLLTMSKLVPE 311

CP000675_0829: domain 1 of 1, from 231 to 295: score 52.0, E = 1.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++++ ++sHELR PL+ ++ ++el +++ +l + +
CP000675_0 231 SKERLIQDISHELRSPLARLKIAIELGKKKT-------KHLADNE-- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ rl++Li ++Ld++r+e
CP000675_0 269 -------------FARMEIETSRLNDLIGEILDFARLEKS 295

CP000675_1168: domain 1 of 1, from 123 to 189: score 47.4, E = 3.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++a l+H++RTPL++ ++y+e L + + l+
CP000675_1 123 SIGTMTAQLAHQIRTPLSSAILYTEHLNN--------LPSLDHRI-- 159

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++ +++++i+dlL ++r +
CP000675_1 160 ----------KNWIHRLQECHASIEQQIQDLLLFARGTSI 189

CP000675_2494: domain 1 of 1, from 138 to 204: score 45.9, E = 9.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+f a+++HELR+P++ +r+++e+ l+ +++ e+
CP000675_2 138 HIKQFSASIAHELRNPIHYLRTATEITLT---------KPQTIET-- 173

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ l+t l+e ++l +Li++lL l+r e+g
CP000675_2 174 ---------YQHVLQTHLEEYQSLTQLIDNLLFLTRCEHG 204

CP000675_1948: domain 1 of 1, from 205 to 273: score 35.7, E = 7e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ef +sH+L+ PL aI+ +a ++e+ +l++
CP000675_1 205 DLEEFSYIISHDLKAPLRAIIQLATWIEEDCG------NKLDSLS-- 243

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ +++ ++r++ +++ lL+++r++
CP000675_1 244 ----------RKNLQLLRERTRRMSGMVDGLLQYARAGRV 273

CP000675_1537: domain 2 of 2, from 592 to 660: score 28.2, E = 9.2e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sH+L+ PL a+ +++ ++e+l +e+ +eq
CP000675_1 592 ELDQFVYHASHDLKAPLPAMEHLISWIEEDL-------GEMLSEQS- 630

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl +++ a r+++L++ lL +++ +
CP000675_1 631 ----------KKYLLLLRQRASRMSKLLDGLLKYAQSGYV 660


Histogram of all scores:
score obs exp (one = represents 11 sequences)
----- --- ---
-15 6 0|=
-14 21 0|==
-13 69 2|*======
-12 193 73|======*===========
-11 312 380|============================= *
-10 519 705|================================================ *
-9 624 728|========================================================= *
-8 501 545|============================================== *
-7 377 343|===============================*===
-6 238 197|=================*====
-5 139 108|=========*===
-4 82 58|=====*==
-3 45 30|==*==
-2 31 16|=*=
-1 19 8|*=
0 7 4|*
1 5 2|*
2 3 1|*
3 2 0|=
4 1 0|=
5 0 0|
> 6 12 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 339.1694
P(chi-square) = 0

Total sequences searched: 3206

Whole sequence top hits:
tophits_s report:
Total hits: 9
Satisfying E cutoff: 9
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 10
Satisfying E cutoff: 10
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: