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Classification of phyla is from NCBI page
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106 projects found  

1 accessions found for Mycobacterium tuberculosis F11  

Data for CP000717  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000717.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000717_1050 CDS_1161723-1160194 86.2 4.2e-24 1
CP000717_3787 CDS_4224103-4222583 83.7 2.1e-23 1
CP000717_3265 CDS_3638391-3636688 74.9 6.8e-21 1
CP000717_0773 CDS_856265-857722 73.5 1.7e-20 1
CP000717_0498 CDS_582518-583750 72.4 3.5e-20 1
CP000717_1046 CDS_1155454-1152872 65.2 3.8e-18 1
CP000717_1000 CDS_1101277-1102791 60.6 7.6e-17 1
CP000717_0920 CDS_1009666-1008326 54.0 5.6e-15 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000717_1050 1/1 277 344 .. 1 87 [] 86.2 4.2e-24
CP000717_3787 1/1 277 343 .. 1 87 [] 83.7 2.1e-23
CP000717_3265 1/1 295 362 .. 1 87 [] 74.9 6.8e-21
CP000717_0773 1/1 249 313 .. 1 87 [] 73.5 1.7e-20
CP000717_0498 1/1 157 223 .. 1 87 [] 72.4 3.5e-20
CP000717_1046 1/1 632 700 .. 1 87 [] 65.2 3.8e-18
CP000717_1000 1/1 239 311 .. 1 87 [] 60.6 7.6e-17
CP000717_0920 1/1 230 296 .. 1 87 [] 54.0 5.6e-15

Alignments of top-scoring domains:
CP000717_1050: domain 1 of 1, from 277 to 344: score 86.2, E = 4.2e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPL+aI+gyael + ++ ++l++ +
CP000717_1 277 RMRQFITDASHELRTPLAAIQGYAELTRQDS-------SDLPPTT-- 314

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +i++ea+r+ L+++lL lsr+ +g
CP000717_1 315 ----------EYALARIESEARRMTLLVDELLLLSRLSEG 344

CP000717_3787: domain 1 of 1, from 277 to 343: score 83.7, E = 2.1e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+aIrgy+el ++ ++e +
CP000717_3 277 RVRQFVADASHELRTPLAAIRGYTELTQR---------IGDDPEAV- 313

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++ +e+er+ rL++dlL l+r+++g
CP000717_3 314 ----------AHAMSRVASETERITRLVEDLLLLARLDSG 343

CP000717_3265: domain 1 of 1, from 295 to 362: score 74.9, E = 6.8e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++++l++
CP000717_3 295 LQRRFTSDVSHELRTPLTTVRMAADLIYD-------HSADLDPTL-- 332

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e + +e++r + L+ndlL++sr +ag
CP000717_3 333 ----------RRSTELMVSELDRFETLLNDLLEISRHDAG 362

CP000717_0773: domain 1 of 1, from 249 to 313: score 73.5, E = 1.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ + ++
CP000717_0 249 RMRQFITDASHELRTPLTTIRGFAELYRQGA-----------ARDV- 283

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++i++ea r+ L++dlL l+r++a
CP000717_0 284 ----------GMLLSRIESEASRMGLLVDDLLLLARLDAH 313

CP000717_0498: domain 1 of 1, from 157 to 223: score 72.4, E = 3.5e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+an+sHEL+TP+ a+ ++ae+Ll+ ++ ++e++
CP000717_0 157 ARRDFVANVSHELKTPVGAMALLAEALLA---------SADDSETV- 193

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ e++l ea+rl +++ +l +lsr++
CP000717_0 194 ----------RRFAEKVLIEANRLGDMVAELIELSRLQGA 223

CP000717_1046: domain 1 of 1, from 632 to 700: score 65.2, E = 3.8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPL+a + +++ L++ +d + s+e++
CP000717_1 632 LRRSLLSAVSHDLRTPLAAAKVAVSSLRT-------EDVAFSPEDT- 670

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l ti++++++l +L+ +lLd sr+ ag
CP000717_1 671 ----------AELLATIEESIDQLTALVANLLDSSRLAAG 700

CP000717_1000: domain 1 of 1, from 239 to 311: score 60.6, E = 7.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +++ ++ HELRTPLt++r+++elL + + ++g + l+ +++
CP000717_1 239 RQARLVTDAGHELRTPLTSLRTNVELLMASM---APGAPRLPKQEM- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +l ++e l+ L+ dl dlsr +ag
CP000717_1 282 ----------VDLRADVLAQIEELSTLVGDLVDLSRGDAG 311

CP000717_0920: domain 1 of 1, from 230 to 296: score 54.0, E = 5.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a sHELRTPLta+r+++e+L + +l+++qr
CP000717_0 230 SARDFAAVSSHELRTPLTAMRTNLEVLST---------LDLPDDQR- 266

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l+ ++r r+++ ++ l l++ e
CP000717_0 267 ----------KEVLNDVIRTQSRIEATLSALERLAQGELS 296


Histogram of all scores:
score obs exp (one = represents 14 sequences)
----- --- ---
-14 2 0|=
-13 38 2|*==
-12 165 90|======*=====
-11 361 467|========================== *
-10 710 866|=================================================== *
-9 816 894|==========================================================*
-8 669 670|===============================================*
-7 488 422|==============================*====
-6 287 243|=================*===
-5 173 133|=========*===
-4 106 71|=====*==
-3 61 37|==*==
-2 29 19|=*=
-1 9 10|*
0 9 5|*
1 2 2|*
2 3 1|*
3 2 0|=
4 1 0|=
5 0 0|
> 6 10 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 189.8648
P(chi-square) = 4.004e-34

Total sequences searched: 3950

Whole sequence top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: