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Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

3 accessions found for Yersinia pseudotuberculosis IP 31758  

Data for CP000720  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000720.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000720_3091 CDS_3529506-3528190 88.2 1.2e-24 1
CP000720_3782 CDS_4311670-4314489 86.8 3e-24 1
CP000720_3275 CDS_3731776-3734568 85.9 5.3e-24 1
CP000720_2725 CDS_3122460-3119611 79.3 3.9e-22 1
CP000720_0458 CDS_545570-547906 75.7 4.3e-21 1
CP000720_2054 CDS_2394700-2396085 69.5 2.4e-19 1
CP000720_1127 CDS_1354006-1355442 68.8 3.8e-19 1
CP000720_1280 CDS_1526862-1525318 67.1 1.2e-18 1
CP000720_1188 CDS_1423227-1421842 67.0 1.3e-18 1
CP000720_2130 CDS_2483694-2487554 65.8 2.7e-18 1
CP000720_0080 CDS_90174-88798 63.6 1.1e-17 1
CP000720_0023 CDS_31911-30862 62.4 2.5e-17 1
CP000720_1080 CDS_1307355-1304629 61.1 5.8e-17 1
CP000720_0856 CDS_1057957-1059390 58.1 4.2e-16 1
CP000720_1289 CDS_1539549-1540898 53.5 8.4e-15 1
CP000720_3923 CDS_4465263-4463911 53.0 1.2e-14 1
CP000720_2780 CDS_3188359-3186545 53.0 1.2e-14 1
CP000720_3558 CDS_4073755-4074822 46.9 6.2e-13 1
CP000720_3973 CDS_4538245-4540800 40.4 4.2e-11 1
CP000720_1796 CDS_2112430-2111126 36.2 6.4e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000720_3091 1/1 203 269 .. 1 87 [] 88.2 1.2e-24
CP000720_3782 1/1 397 462 .. 1 87 [] 86.8 3e-24
CP000720_3275 1/1 291 356 .. 1 87 [] 85.9 5.3e-24
CP000720_2725 1/1 471 536 .. 1 87 [] 79.3 3.9e-22
CP000720_0458 1/1 282 347 .. 1 87 [] 75.7 4.3e-21
CP000720_2054 1/1 238 304 .. 1 87 [] 69.5 2.4e-19
CP000720_1127 1/1 252 320 .. 1 87 [] 68.8 3.8e-19
CP000720_1280 1/1 280 350 .. 1 87 [] 67.1 1.2e-18
CP000720_1188 1/1 237 301 .. 1 87 [] 67.0 1.3e-18
CP000720_2130 1/1 692 756 .. 1 87 [] 65.8 2.7e-18
CP000720_0080 1/1 238 300 .. 1 87 [] 63.6 1.1e-17
CP000720_0023 1/1 129 194 .. 1 87 [] 62.4 2.5e-17
CP000720_1080 1/1 665 732 .. 1 87 [] 61.1 5.8e-17
CP000720_0856 1/1 255 320 .. 1 87 [] 58.1 4.2e-16
CP000720_1289 1/1 228 291 .. 1 87 [] 53.5 8.4e-15
CP000720_3923 1/1 233 293 .. 1 87 [] 53.0 1.2e-14
CP000720_2780 1/1 370 436 .. 1 87 [] 53.0 1.2e-14
CP000720_3558 1/1 136 196 .. 1 87 [] 46.9 6.2e-13
CP000720_3973 1/1 497 559 .. 1 87 [] 40.4 4.2e-11
CP000720_1796 1/1 211 271 .. 1 87 [] 36.2 6.4e-10

Alignments of top-scoring domains:
CP000720_3091: domain 1 of 1, from 203 to 269: score 88.2, E = 1.2e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ + +el + r
CP000720_3 203 ARRNFFANVSHELRTPLTVLQGYLEMMHD---------QELAGPLR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l t++++++r++ L+ +lL+lsriea
CP000720_3 240 ----------DKALGTMQEQTKRMDGLVKQLLTLSRIEAA 269

CP000720_3782: domain 1 of 1, from 397 to 462: score 86.8, E = 3e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+ l ++sHE+RTPL++ +g++elL++ t+l++ q
CP000720_3 397 RKSDHLTTISHEIRTPLNGALGAVELLQN---------TPLDAGQ-- 432

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ et+++++ +ll++in+lLd+srie+g
CP000720_3 433 ----------MRLAETAHQCSLSLLAIINNLLDFSRIESG 462

CP000720_3275: domain 1 of 1, from 291 to 356: score 85.9, E = 5.3e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l+ t l++ q
CP000720_3 291 IKSEFLANMSHELRTPLNGVIGFTRQTLK---------TSLTPTQ-- 326

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ti+r+a+ ll +ind+Ld+s++ea
CP000720_3 327 ----------TDYLQTIQRSANNLLCIINDVLDFSKLEAD 356

CP000720_2725: domain 1 of 1, from 471 to 536: score 79.3, E = 3.9e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP000720_2 471 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPQGV-- 506

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP000720_2 507 ----------DRLVTAMNNSSGLLLKIISDILDFSKIESE 536

CP000720_0458: domain 1 of 1, from 282 to 347: score 75.7, E = 4.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP000720_0 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELDAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ti+ +a l ++ nd+ ++ ++e
CP000720_0 318 ----------LKYLKTIHVSAITLGNIFNDIIEMDKLERR 347

CP000720_2054: domain 1 of 1, from 238 to 304: score 69.5, E = 2.4e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f a+++HELRTPLt ++g ++l l ++ ++
CP000720_2 238 QLESFNADVAHELRTPLTNLMGQTQLGLS---------RKRETHEL- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++le+ l+e+er+ +++nd+L ls ++ag
CP000720_2 275 ----------EDLLESNLEELERMTSIVNDMLFLSHAQAG 304

CP000720_1127: domain 1 of 1, from 252 to 320: score 68.8, E = 3.8e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ efl+++sHEL+TPL+++r +elL +e+ ++l+ +q
CP000720_1 252 QRHEFLRHISHELKTPLASMREGTELLADEVA------GPLTQDQ-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++++++++l++Li++lLd+ r a
CP000720_1 291 ----------QEVVAILDHSSRHLQQLIEQLLDYNRKLAD 320

CP000720_1280: domain 1 of 1, from 280 to 350: score 67.1, E = 1.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+ +sHEL+TPLt I +yae+L+e l+ ++ ++
CP000720_1 280 QQVSFVGQVSHELKTPLTNITLYAEMLQE-----LQPEQSVPPTAE- 320

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle+il+e++rl+rLi+++L ++++
CP000720_1 321 ----------QRYLEVILNESQRLSRLIQNILSFTKAPKL 350

CP000720_1188: domain 1 of 1, from 237 to 301: score 67.0, E = 1.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e+L+++l ++e
CP000720_1 237 MRRDFMADVSHELRTPLAVLRGELEALQDGL-------RQPTPES-- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l++++ e+ l +L+ndl +ls+ + g
CP000720_1 275 -------------LSSLQAEVAILTKLVNDLHQLSQSDRG 301

CP000720_2130: domain 1 of 1, from 692 to 756: score 65.8, E = 2.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks fla++sHELRTP+ aI+g++el + ++++ e+
CP000720_2 692 TKSTFLATISHELRTPMYAIMGLLELEIR---------SNRPVEK-- 727

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l t+ ++a++l L++d+ d ++ieag
CP000720_2 728 -----------DTLVTVSKSAQSLMLLLDDIIDSAKIEAG 756

CP000720_0080: domain 1 of 1, from 238 to 300: score 63.6, E = 1.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++++++sHELRTPLt +++++ l+++ + ++
CP000720_0 238 AQQRLISDISHELRTPLTRLQLATALMRR---------RHGEGKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL lsr ++
CP000720_0 274 -------------LERIEMEAQRLDSMINDLLVLSRSQHK 300

CP000720_0023: domain 1 of 1, from 129 to 194: score 62.4, E = 2.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP000720_0 129 AARDLVRGLAHEIKNPLGGLRGAAQLLAK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+++i+++a+rl++L+++lL r ++
CP000720_0 165 ----------LEYTQVIIEQADRLRNLVDRLLGPQRPGQH 194

CP000720_1080: domain 1 of 1, from 665 to 732: score 61.1, E = 5.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l ++ ++ +
CP000720_1 665 LRNSLLAALSHDLRTPLTVLFGQAEILTLDL-------AAEGSRH-- 702

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i++++ + rL+n+lLd++ri++g
CP000720_1 703 ----------APQANQIRQQVLSTTRLVNNLLDMARIQSG 732

CP000720_0856: domain 1 of 1, from 255 to 320: score 58.1, E = 4.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aI+g+aelL+e ++ +e
CP000720_0 255 YIEQYVHTLTHELKSPLAAISGAAELLRE---------SPPPETA-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i++++ r+++L++ +L +r+e+
CP000720_0 291 ----------QRFLINIEQQSARIQQLVDKMLVQARLESR 320

CP000720_1289: domain 1 of 1, from 228 to 291: score 53.5, E = 8.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++l ++sHELR PL+ +++++ l +++++ +
CP000720_1 228 AREQLLHDVSHELRSPLARLQLAIGL------------AHQNPGNV- 261

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++i++e+erl+++i +lL lsr+e+
CP000720_1 262 ----------DNALQRIEHESERLDKMIGELLALSRAENH 291

CP000720_3923: domain 1 of 1, from 233 to 293: score 53.0, E = 1.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP000720_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE--------------DD-- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP000720_3 264 ----------GYLSESINKDIEECNAIIEQFIDYLRTGQE 293

CP000720_2780: domain 1 of 1, from 370 to 436: score 53.0, E = 1.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++a+++HE+R+PL++I+g+a+ + +++++e+
CP000720_2 370 AIGNLAAGVAHEIRNPLSSIKGFAKYFEG--------HSPQGSEE-- 406

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ +++++e++rl+r + +lL l r
CP000720_2 407 ----------QELAKVMIKEVDRLNRAVTELLGLVRPSDL 436

CP000720_3558: domain 1 of 1, from 136 to 196: score 46.9, E = 6.2e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL++Ir+++el+++ + e +
CP000720_3 136 QERLFTADAAHELRTPLAGIRLHLELMEK---------QGIAESK-- 171

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ ++ l + i++lL lsr++++
CP000720_3 172 ---------------SLINRIDLLMHTIEQLLMLSRAGQN 196

CP000720_3973: domain 1 of 1, from 497 to 559: score 40.4, E = 4.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + + s+ +r
CP000720_3 497 AVGQLTGGLAHDFNNLLAVIIGSLELTAT----------DSSDATR- 532

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++l++aer +L ++lL +sr ++
CP000720_3 533 -------------IHRALKAAERGAQLTQRLLAFSRKQSL 559

CP000720_1796: domain 1 of 1, from 211 to 271: score 36.2, E = 6.4e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k ++ +++HELRTPL +r + + + l+e ++
CP000720_1 211 SKKLLIDGIAHELRTPLVRLRYRLAMSDN-----------LTESEQ- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++ +l++Li++lL+++r++ +
CP000720_1 246 --------------QALHHDIGQLEALIDELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-15 10 0|=
-14 37 0|===
-13 107 3|*========
-12 218 94|=======*=========
-11 398 488|=============================== *
-10 662 906|=================================================== *
-9 758 936|==========================================================*
-8 696 701|=====================================================*
-7 475 441|=================================*===
-6 316 254|===================*=====
-5 192 139|==========*====
-4 110 74|=====*===
-3 50 39|==*=
-2 27 20|=*=
-1 25 10|*=
0 6 5|*
1 6 2|*
2 3 1|*
3 1 0|=
4 3 0|=
5 0 0|
6 1 0|=
> 7 23 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 356.8352
P(chi-square) = 0

Total sequences searched: 4124

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: