hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000759.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]
Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000759_1165 CDS_1334226-1337393 88.3 4.6e-25 1
CP000759_1022 CDS_1167420-1170158 74.2 4.6e-21 1
CP000759_0758 CDS_880142-878754 56.0 6.7e-16 1
CP000759_0496 CDS_572059-570719 53.1 4.3e-15 1
CP000759_0722 CDS_841194-839329 39.5 3.2e-11 1
CP000759_1366 CDS_1559357-1557819 36.4 2.4e-10 1
CP000759_0357 CDS_430656-432434 31.0 8.2e-09 1
Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000759_1165 1/1 815 884 .. 1 87 [] 88.3 4.6e-25
CP000759_1022 1/1 681 749 .. 1 87 [] 74.2 4.6e-21
CP000759_0758 1/1 243 308 .. 1 87 [] 56.0 6.7e-16
CP000759_0496 1/1 230 295 .. 1 87 [] 53.1 4.3e-15
CP000759_0722 1/1 404 472 .. 1 87 [] 39.5 3.2e-11
CP000759_1366 1/1 290 358 .. 1 87 [] 36.4 2.4e-10
CP000759_0357 1/1 367 435 .. 1 87 [] 31.0 8.2e-09
Alignments of top-scoring domains:
CP000759_1165: domain 1 of 1, from 815 to 884: score 88.3, E = 4.6e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+efla +sHE+RTPL+aI+g++el+ + + + + +
CP000759_1 815 QKTEFLARISHEIRTPLNAIIGFSELMAD------EKFGSIGNDR-- 853
peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+yl+ i r++++ l+L+ndlLd+s+ieag
CP000759_1 854 ---------YRDYLRDINRSGNHVLALVNDLLDISKIEAG 884
CP000759_1022: domain 1 of 1, from 681 to 749: score 74.2, E = 4.6e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s +l ++sH+L+TPL+aI+g+a +L++++ + l++ +r
CP000759_1 681 LRSALLTSISHDLKTPLAAILGAATTLRDYS-------SSLPDTDR- 719
peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ t+ +++erl+r i +lLd++rieag
CP000759_1 720 ----------SDLVATVVDQSERLNRFIANLLDMTRIEAG 749
CP000759_0758: domain 1 of 1, from 243 to 308: score 56.0, E = 6.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+ +f+ n++H+LRTPL+++++ a+ +++ t++ ++
CP000759_0 243 AQHRFIQNAAHQLRTPLATLSTQASFAER---------TTCESDR-- 278
peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l i++ + +l+rL +lL+lsr+e g
CP000759_0 279 ----------KDVLAGIKNTTMQLSRLAGQLLTLSRAEPG 308
CP000759_0496: domain 1 of 1, from 230 to 295: score 53.1, E = 4.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a ++HELRTPL+++++ a+++l+ +++ + +
CP000759_0 230 RERNFTAFAAHELRTPLAGLKTQAQVALA--------SGDGTIRE-- 266
peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l+ i ++r rL+++lLd+s ea
CP000759_0 267 -----------QALRQIMVGVDRTGRLVRQLLDMSAVEAL 295
CP000759_0722: domain 1 of 1, from 404 to 472: score 39.5, E = 3.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +a+++HE+++P+++Ir+ya+ ++++ + ++ ++
CP000759_0 404 IMGQVAAGVAHEINQPVATIRAYADNAKTFIE------RKRLSDA-- 442
peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e l+ i ++r+ + dl l+r +
CP000759_0 443 ----------TENLSEIAALTDRIGTITGDLKALARKGRT 472
CP000759_1366: domain 1 of 1, from 290 to 358: score 36.4, E = 2.4e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL +PLta+++ a++ ++ l+++ ++++
CP000759_1 290 TMGEMASGMAHELTQPLTALLAGAQAGRR-----LLSRNNMTALA-- 329
peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l+ + ++a+r ++++++l+ sr +
CP000759_1 330 -----------GALDDMVDQARRASAILDRLRNWSRPQRR 358
CP000759_0357: domain 1 of 1, from 367 to 435: score 31.0, E = 8.2e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +a+l HE+++P+++Ir+++e ++ + ++ +++
CP000759_0 367 SLGSITAGLVHEINQPVATIRTLTENAQH-------HLAHGKLDKV- 405
peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l+t + + r+ ++ ++++ ++r ++g
CP000759_0 406 ----------AQNLNTSVELTARIGSITQEMRRFARRRSG 435
Histogram of all scores:
score obs exp (one = represents 7 sequences)
----- --- ---
-14 1 0|=
-13 15 1|*==
-12 55 38|=====*==
-11 145 200|===================== *
-10 266 372|====================================== *
-9 379 384|======================================================*
-8 297 287|========================================*==
-7 228 181|=========================*=======
-6 128 104|==============*====
-5 79 57|========*===
-4 42 30|====*=
-3 27 16|==*=
-2 5 8|=*
-1 10 4|*=
0 2 2|*
1 2 1|*
2 1 0|=
3 2 0|=
> 4 9 -|==
% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 91.4386
P(chi-square) = 2.776e-15
Total sequences searched: 1693
Whole sequence top hits:
tophits_s report:
Total hits: 7
Satisfying E cutoff: 7
Total memory: 21K
Domain top hits:
tophits_s report:
Total hits: 7
Satisfying E cutoff: 7
Total memory: 23K
