Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
264 projects found  

1 accessions found for Escherichia coli HS  

Data for CP000802  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000802.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000802_2773 CDS_2933266-2936022 100.1 5.3e-28 1
CP000802_0451 CDS_481681-482976 91.0 2.1e-25 1
CP000802_2376 CDS_2515779-2519372 81.6 9.4e-23 1
CP000802_1046 CDS_1117014-1114270 80.7 1.7e-22 1
CP000802_2235 CDS_2360858-2358009 80.6 1.9e-22 1
CP000802_3227 CDS_3403952-3401616 78.9 5.6e-22 1
CP000802_2236 CDS_2361025-2362851 76.4 2.9e-21 1
CP000802_2566 CDS_2729432-2728005 75.4 5.5e-21 1
CP000802_2102 CDS_2207117-2208520 69.8 2.2e-19 1
CP000802_3918 CDS_4132984-4131611 66.6 1.7e-18 1
CP000802_4380 CDS_4638582-4640006 62.4 2.6e-17 1
CP000802_4005 CDS_4231508-4232884 61.5 4.7e-17 1
CP000802_0595 CDS_630864-629416 61.0 6.5e-17 1
CP000802_3035 CDS_3215315-3216664 60.7 8.2e-17 1
CP000802_3874 CDS_4086478-4085429 59.7 1.6e-16 1
CP000802_0708 CDS_750494-747810 59.6 1.6e-16 1
CP000802_3414 CDS_3580227-3578875 55.0 3.3e-15 1
CP000802_1969 CDS_2057252-2055894 52.3 1.8e-14 1
CP000802_4110 CDS_4357293-4356202 45.0 2.2e-12 1
CP000802_1603 CDS_1705016-1706317 42.4 1.2e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000802_2773 1/1 292 357 .. 1 87 [] 100.1 5.3e-28
CP000802_0451 1/1 203 269 .. 1 87 [] 91.0 2.1e-25
CP000802_2376 1/1 711 777 .. 1 87 [] 81.6 9.4e-23
CP000802_1046 1/1 443 508 .. 1 87 [] 80.7 1.7e-22
CP000802_2235 1/1 469 534 .. 1 87 [] 80.6 1.9e-22
CP000802_3227 1/1 282 347 .. 1 87 [] 78.9 5.6e-22
CP000802_2236 1/1 388 453 .. 1 87 [] 76.4 2.9e-21
CP000802_2566 1/1 249 317 .. 1 87 [] 75.4 5.5e-21
CP000802_2102 1/1 240 304 .. 1 87 [] 69.8 2.2e-19
CP000802_3918 1/1 238 300 .. 1 87 [] 66.6 1.7e-18
CP000802_4380 1/1 255 320 .. 1 87 [] 62.4 2.6e-17
CP000802_4005 1/1 237 303 .. 1 87 [] 61.5 4.7e-17
CP000802_0595 1/1 261 327 .. 1 87 [] 61.0 6.5e-17
CP000802_3035 1/1 236 302 .. 1 87 [] 60.7 8.2e-17
CP000802_3874 1/1 129 186 .. 1 79 [. 59.7 1.6e-16
CP000802_0708 1/1 663 730 .. 1 87 [] 59.6 1.6e-16
CP000802_3414 1/1 233 293 .. 1 87 [] 55.0 3.3e-15
CP000802_1969 1/1 235 301 .. 1 87 [] 52.3 1.8e-14
CP000802_4110 1/1 142 202 .. 1 87 [] 45.0 2.2e-12
CP000802_1603 1/1 211 271 .. 1 87 [] 42.4 1.2e-11

Alignments of top-scoring domains:
CP000802_2773: domain 1 of 1, from 292 to 357: score 100.1, E = 5.3e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CP000802_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP000802_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CP000802_0451: domain 1 of 1, from 203 to 269: score 91.0, E = 2.1e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CP000802_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CP000802_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CP000802_2376: domain 1 of 1, from 711 to 777: score 81.6, E = 9.4e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CP000802_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CP000802_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

CP000802_1046: domain 1 of 1, from 443 to 508: score 80.7, E = 1.7e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
CP000802_1 443 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
CP000802_1 479 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 508

CP000802_2235: domain 1 of 1, from 469 to 534: score 80.6, E = 1.9e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP000802_2 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP000802_2 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

CP000802_3227: domain 1 of 1, from 282 to 347: score 78.9, E = 5.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP000802_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP000802_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP000802_2236: domain 1 of 1, from 388 to 453: score 76.4, E = 2.9e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ ++ ++ +
CP000802_2 388 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTSDPIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
CP000802_2 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

CP000802_2566: domain 1 of 1, from 249 to 317: score 75.4, E = 5.5e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP000802_2 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
CP000802_2 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

CP000802_2102: domain 1 of 1, from 240 to 304: score 69.8, E = 2.2e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
CP000802_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP000802_2 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

CP000802_3918: domain 1 of 1, from 238 to 300: score 66.6, E = 1.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP000802_3 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP000802_3 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP000802_4380: domain 1 of 1, from 255 to 320: score 62.4, E = 2.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CP000802_4 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CP000802_4 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CP000802_4005: domain 1 of 1, from 237 to 303: score 61.5, E = 4.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
CP000802_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
CP000802_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

CP000802_0595: domain 1 of 1, from 261 to 327: score 61.0, E = 6.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CP000802_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CP000802_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

CP000802_3035: domain 1 of 1, from 236 to 302: score 60.7, E = 8.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CP000802_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CP000802_3 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

CP000802_3874: domain 1 of 1, from 129 to 186: score 59.7, E = 1.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP000802_3 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP000802_3 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CP000802_0708: domain 1 of 1, from 663 to 730: score 59.6, E = 1.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CP000802_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CP000802_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CP000802_3414: domain 1 of 1, from 233 to 293: score 55.0, E = 3.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP000802_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP000802_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP000802_1969: domain 1 of 1, from 235 to 301: score 52.3, E = 1.8e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
CP000802_1 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CP000802_1 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CP000802_4110: domain 1 of 1, from 142 to 202: score 45.0, E = 2.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CP000802_4 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CP000802_4 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

CP000802_1603: domain 1 of 1, from 211 to 271: score 42.4, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CP000802_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP000802_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 14 sequences)
----- --- ---
-16 1 0|=
-15 7 0|=
-14 55 0|====
-13 98 3|*======
-12 235 100|=======*=========
-11 456 519|================================= *
-10 710 964|=================================================== *
-9 786 995|========================================================= *
-8 706 745|=================================================== *
-7 512 469|=================================*===
-6 345 270|===================*=====
-5 204 148|==========*====
-4 90 79|=====*=
-3 55 41|==*=
-2 34 21|=*=
-1 35 11|*==
0 17 5|*=
1 7 3|*
2 7 1|*
3 2 0|=
4 0 0|
> 5 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 427.9037
P(chi-square) = 0

Total sequences searched: 4384

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: