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Classification of phyla is from NCBI page
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106 projects found  

2 accessions found for Mycobacterium marinum M  

Data for CP000854  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000854.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000854_4392 CDS_5475080-5476624 88.9 9.8e-25 1
CP000854_5249 CDS_6424203-6422689 76.3 3.8e-21 1
CP000854_1287 CDS_1584281-1585960 75.4 6.7e-21 1
CP000854_4874 CDS_6001044-5999599 72.2 5.4e-20 1
CP000854_0804 CDS_977583-978809 69.9 2.5e-19 1
CP000854_0624 CDS_747565-750084 66.7 1.9e-18 1
CP000854_0727 CDS_885627-889490 64.7 7.1e-18 1
CP000854_4463 CDS_5557634-5556099 62.0 4.2e-17 1
CP000854_4566 CDS_5686255-5687604 53.4 1.1e-14 1
CP000854_2277 CDS_2763233-2764753 51.1 5e-14 1
CP000854_1251 CDS_1543772-1545394 41.3 3.1e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000854_4392 1/1 272 339 .. 1 87 [] 88.9 9.8e-25
CP000854_5249 1/1 275 341 .. 1 87 [] 76.3 3.8e-21
CP000854_1287 1/1 295 362 .. 1 87 [] 75.4 6.7e-21
CP000854_4874 1/1 249 313 .. 1 87 [] 72.2 5.4e-20
CP000854_0804 1/1 156 222 .. 1 87 [] 69.9 2.5e-19
CP000854_0624 1/1 615 683 .. 1 87 [] 66.7 1.9e-18
CP000854_0727 1/1 357 423 .. 1 87 [] 64.7 7.1e-18
CP000854_4463 1/1 239 311 .. 1 87 [] 62.0 4.2e-17
CP000854_4566 1/1 233 299 .. 1 87 [] 53.4 1.1e-14
CP000854_2277 1/1 276 348 .. 1 87 [] 51.1 5e-14
CP000854_1251 1/1 296 364 .. 1 87 [] 41.3 3.1e-11

Alignments of top-scoring domains:
CP000854_4392: domain 1 of 1, from 272 to 339: score 88.9, E = 9.8e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPL+aI+gyael + ++ ++l++ +
CP000854_4 272 RMRQFITDASHELRTPLAAIQGYAELTRQDS-------SDLPPTT-- 309

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l +i++ea+r+ +L+++lL lsr+++g
CP000854_4 310 ----------EYALARIESEARRMASLVDELLLLSRLGEG 339

CP000854_5249: domain 1 of 1, from 275 to 341: score 76.3, E = 3.8e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+aIrgy+el+++ ++ +
CP000854_5 275 RVRQFVADASHELRTPLAAIRGYTELAQR----------MGDDRAA- 310

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + +++ +e+er+ +L++dlL l+r+++g
CP000854_5 311 ---------VAHAMSRVGSETERITSLVEDLLLLARLDSG 341

CP000854_1287: domain 1 of 1, from 295 to 362: score 75.4, E = 6.7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++++l++
CP000854_1 295 LQRRFTSDVSHELRTPLTTVRMAADLIYD-------HSADLDPTL-- 332

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e + +e++r ++L+ndlL++sr +ag
CP000854_1 333 ----------RRSTELMVNELDRFESLLNDLLEISRHDAG 362

CP000854_4874: domain 1 of 1, from 249 to 313: score 72.2, E = 5.4e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ + ++
CP000854_4 249 RMRRFITDASHELRTPLTTIRGFAELYRQGA-----------ARDV- 283

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l++i++ea r+ L++dlL+l+r++ +
CP000854_4 284 ----------AMLLSRIESEASRMGLLVDDLLTLARLDVQ 313

CP000854_0804: domain 1 of 1, from 156 to 222: score 69.9, E = 2.5e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a+ ++ae+Ll+ ++ +++++
CP000854_0 156 TRRDFVANVSHELKTPVGAMALLAEALLA---------SADDSDTV- 192

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ e++l ea+rl +++ +l +lsr++
CP000854_0 193 ----------RRFAEKVLIEANRLGDMVAELIELSRLQGA 222

CP000854_0624: domain 1 of 1, from 615 to 683: score 66.7, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPL+a +++++ L+ d + s++++
CP000854_0 615 LRRALLSAVSHDLRTPLAAAKAAVSSLRS-------DDVDFSADDM- 653

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+l ti++++++l +L+ +lLd sr+ ag
CP000854_0 654 ----------GELLATIEESVDQLTALVGNLLDSSRLAAG 683

CP000854_0727: domain 1 of 1, from 357 to 423: score 64.7, E = 7.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl n+sHE+RTPLt ++g +e +l+ ++ ++ +
CP000854_0 357 AKTAFLTNVSHEFRTPLTLLLGPVEDALA---------DAGGDTVL- 393

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l+t++r a+rl+r+++ lL +srieag
CP000854_0 394 ----------ADRLDTARRNARRLQRMVDSLLAFSRIEAG 423

CP000854_4463: domain 1 of 1, from 239 to 311: score 62.0, E = 4.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++++++ HELRTPLt++r+++elL + ++ +g + l+e+++
CP000854_4 239 RQARLVSDAGHELRTPLTSLRTNVELLMASME---PGAPRLPEQEM- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e + ++e l+ L+ dl dl+r +ag
CP000854_4 282 ----------VGLREDVVAQIEELSTLVGDLVDLTRGDAG 311

CP000854_4566: domain 1 of 1, from 233 to 299: score 53.4, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a sHELRTPLta+r+++e+L + +l+++qr
CP000854_4 233 SARDFAAVSSHELRTPLTAMRTNLEVLST---------LDLPDDQR- 269

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l+ ++r r+++ + l l++ e
CP000854_4 270 ----------KEVLNDVIRTQSRIEATLGALERLAQGELS 299

CP000854_2277: domain 1 of 1, from 276 to 348: score 51.1, E = 5e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++fl +++HELRTP+++++ +ae L ++ + e+
CP000854_2 276 ATRQFLVDAAHELRTPIAGMQVAAEQLAS--------SAGQQQED-- 312

peLR.ledpeyreyletilreaerllrLindlLdlsrieag<-*
p++R+ + + +l++a+r rL+ d+Ldlsri+ag
CP000854_2 313 PAARgQ-----YRRASLLLSDARRAGRLVADMLDLSRIDAG 348

CP000854_1251: domain 1 of 1, from 296 to 364: score 41.3, E = 3.1e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL + ++++lL++++ + l+e +
CP000854_1 296 ELEQFAYVASHDLQEPLRKVAAFCQLLERRYA------DQLDERGI- 335

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+ + + a+r++ LindlL +sr +
CP000854_1 336 -----------EYIGFAVDGAKRMQVLINDLLSFSRVGRL 364


Histogram of all scores:
score obs exp (one = represents 19 sequences)
----- --- ---
-15 1 0|=
-14 13 0|=
-13 44 4|*==
-12 229 123|======*======
-11 501 642|=========================== *
-10 933 1192|================================================== *
-9 1103 1231|==========================================================*
-8 937 922|================================================*=
-7 690 581|==============================*======
-6 414 334|=================*====
-5 237 183|=========*===
-4 146 98|=====*==
-3 59 51|==*=
-2 50 27|=*=
-1 27 14|*=
0 13 7|*
1 7 3|*
2 3 2|*
3 3 1|*
> 4 13 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 304.4996
P(chi-square) = 0

Total sequences searched: 5423

Whole sequence top hits:
tophits_s report:
Total hits: 11
Satisfying E cutoff: 11
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 11
Satisfying E cutoff: 11
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: