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Thermotogae
Classification of phyla is from NCBI page
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4 accessions found for   

Data for CP000868  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000868.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000868_2004 CDS_2208511-2207192 92.9 4.3e-26 1
CP000868_0648 CDS_713201-711654 67.3 7.8e-19 1
CP000868_0989 CDS_1087778-1090633 65.4 2.7e-18 1
CP000868_1118 CDS_1232544-1233725 61.1 4.5e-17 1
CP000868_2326 CDS_2546338-2544917 57.5 4.7e-16 1
CP000868_0681 CDS_745408-746754 56.0 1.2e-15 1
CP000868_0074 CDS_81261-79780 55.5 1.7e-15 1
CP000868_0889 CDS_974708-976024 52.6 1.1e-14 1
CP000868_0033 CDS_40551-39184 47.4 3.4e-13 1
CP000868_1127 CDS_1247274-1244758 40.9 2.3e-11 1
CP000868_1325 CDS_1465113-1463752 40.7 2.7e-11 1
CP000868_3107 CDS_3406761-3404308 38.2 1.4e-10 1
CP000868_0431 CDS_474123-476129 34.4 1.6e-09 1
CP000868_3079 CDS_3374103-3372700 27.1 1.9e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000868_2004 1/1 206 272 .. 1 87 [] 92.9 4.3e-26
CP000868_0648 1/1 281 346 .. 1 87 [] 67.3 7.8e-19
CP000868_0989 1/1 678 756 .. 1 87 [] 65.4 2.7e-18
CP000868_1118 1/1 165 233 .. 1 87 [] 61.1 4.5e-17
CP000868_2326 1/1 252 318 .. 1 87 [] 57.5 4.7e-16
CP000868_0681 1/1 213 278 .. 1 87 [] 56.0 1.2e-15
CP000868_0074 1/1 239 304 .. 1 87 [] 55.5 1.7e-15
CP000868_0889 1/1 220 278 .. 1 87 [] 52.6 1.1e-14
CP000868_0033 1/1 235 301 .. 1 87 [] 47.4 3.4e-13
CP000868_1127 1/1 588 658 .. 1 87 [] 40.9 2.3e-11
CP000868_1325 1/1 234 293 .. 1 87 [] 40.7 2.7e-11
CP000868_3107 1/1 541 613 .. 1 87 [] 38.2 1.4e-10
CP000868_0431 1/1 419 481 .. 1 81 [. 34.4 1.6e-09
CP000868_3079 1/1 201 270 .. 1 87 [] 27.1 1.9e-07

Alignments of top-scoring domains:
CP000868_2004: domain 1 of 1, from 206 to 272: score 92.9, E = 4.3e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt+++g++e+++e +l+ee+r
CP000868_2 206 MRRDFVANVSHELKTPLTVLSGFLETMRE---------LPLGEEDR- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle ++++a r+++++ dlL l+++e +
CP000868_2 243 ----------ARYLEMMEQQASRMRHIVTDLLVLAKLEGE 272

CP000868_0648: domain 1 of 1, from 281 to 346: score 67.3, E = 7.8e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ae +l+ ++ +++
CP000868_0 281 LQKRFIADAAHQMKTPLAGLRTQAEFALR---------HPVPPDV-- 316

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ le i ++e+ rL+ +lL l+r+e+
CP000868_0 317 ----------QRSLEQIATSSEQAARLVTQLLALARAENR 346

CP000868_0989: domain 1 of 1, from 678 to 756: score 65.4, E = 2.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPLt+I g++++L + g++++s +++
CP000868_0 678 LRNSLLSAISHDLRTPLTTIVGFSSMLAN-------GRAAASFGDAA 717

peLR....ledpeyreyletilreaerllrLindlLdlsrieag<-*
++R +++ e+++ i++ea r+ ++ +lLd++r++ag
CP000868_0 718 AAARlaqrE-----GELVDAIHDEALRMTGIVTNLLDMARLQAG 756

CP000868_1118: domain 1 of 1, from 165 to 233: score 61.1, E = 4.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++nl+HE+++PL +Irg+a+lL+ el +e+ ++
CP000868_1 165 VNKQLIRNLAHEIKNPLGGIRGAAQLLEFEL-------GERERGEL- 203

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey+++i++e++rl+ L+++lL+ r +
CP000868_1 204 ----------REYTQVIIKESDRLQTLVDRLLEPHRHPHI 233

CP000868_2326: domain 1 of 1, from 252 to 318: score 57.5, E = 4.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f a+++HELRTP+t + + +e++l + +s+e+
CP000868_2 252 QLANFSADIAHELRTPVTNLTTQTEVALG---------QSRSAEE-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yre l + l+e r++r+i d+L l++ e+
CP000868_2 288 ---------YREVLYSNLEEFGRMSRMIGDMLFLAQTEND 318

CP000868_0681: domain 1 of 1, from 213 to 278: score 56.0, E = 1.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+a++ a+l + ++ ++
CP000868_0 213 TQKAFVADAAHELRTPLAAVQIQAQLVAR---------AKDDAAR-- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re+l+ +++ + r rL ++lL l+r+e
CP000868_0 249 ----------REALDDLQHGVTRATRLAEQLLALARAEPD 278

CP000868_0074: domain 1 of 1, from 239 to 304: score 55.5, E = 1.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLta++++ae + +++ +q+
CP000868_0 239 AQRKFIADAAHQLRTPLTAVKLHAEQAAV----------ARDTQQT- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l+ ++ +a+r rL n+lL l+r+e g
CP000868_0 275 ----------YAALRELRAAADRAVRLSNQLLSLARAEPG 304

CP000868_0889: domain 1 of 1, from 220 to 278: score 52.6, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+LRTPL+ +r+ ae++ +
CP000868_0 220 DRAVMLAGVAHDLRTPLARMRLRAEMMDD------------------ 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + + r+++++ ++++++L ++ +a
CP000868_0 249 ----------ARLRDGVVRDVDSMTHIVDQFLVFAHGGAD 278

CP000868_0033: domain 1 of 1, from 235 to 301: score 47.4, E = 3.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++H+LRTP++++ + ++ ++ ++ ++
CP000868_0 235 TQRRFIADAAHQLRTPIAVLDTQIQYAQQ---------RGNDDREL- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l++++r+++ + + + lL l+ +ea
CP000868_0 272 ----------ASVLDSMQRSSRKMADVTDKLLLLAHAEAT 301

CP000868_1127: domain 1 of 1, from 588 to 658: score 40.9, E = 2.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL++PL+aI y++ l+ l +++ ++e +
CP000868_1 588 TMGEMASSIAHELNQPLAAINNYCSGTLA-----LVKSGRGTPEML- 628

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le+ ++a r ++ +++++ + ++
CP000868_1 629 ----------QPALEKTAQQALRAGMIVKRIREFVKRSEP 658

CP000868_1325: domain 1 of 1, from 234 to 293: score 40.7, E = 2.7e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ +
CP000868_1 234 DRALMLAGISHDLRTPLARLRLETEMSPSD----------------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + +++e+++r+i + d++r +
CP000868_1 264 ----------QATKDAMVDDIEQMDRIIAAFIDYARPTQR 293

CP000868_3107: domain 1 of 1, from 541 to 613: score 38.2, E = 1.4e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l + + ++ +++ +
CP000868_3 541 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL---SDKLAPHDADVL- 583

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ i +++ + r+++d+++++r
CP000868_3 584 ----------KRGATMIVNQVAAMKRMVDDFREYARTPPA 613

CP000868_0431: domain 1 of 1, from 419 to 481: score 34.4, E = 1.6e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+a+r +++ + +++e+ ++
CP000868_0 419 ALGQMAAGITHELNQPLAALRSFSDNTRV--------LLDRGEQAAA 457

peLRledpeyreyletilreaerllrLindlLdl<-*
re le i +er+ ++ n+l +
CP000868_0 458 ----------RENLEAIAALTERMGKITNQLKLF 481

CP000868_3079: domain 1 of 1, from 201 to 270: score 27.1, E = 1.9e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ +a+++HE+ TPL++I ++ae L++ ++++++ ++
CP000868_3 201 ALGVQAATVAHEMGTPLSTIAMLAEELRD---------AARDDPGLA 238

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + l++++++ + + + +l+ + + a
CP000868_3 239 RY--------EADLKVLEEQMMLCTSALARLRSRASAPAS 270


Histogram of all scores:
score obs exp (one = represents 10 sequences)
----- --- ---
-14 6 0|=
-13 28 2|*==
-12 111 71|=======*====
-11 297 372|============================== *
-10 508 691|=================================================== *
-9 589 714|==========================================================*
-8 588 534|=====================================================*=====
-7 408 337|=================================*=======
-6 262 194|===================*=======
-5 152 106|==========*=====
-4 85 56|=====*===
-3 40 30|==*=
-2 28 15|=*=
-1 14 8|*=
0 10 4|*
1 3 2|*
2 1 1|*
3 0 0|
> 4 16 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 201.6469
P(chi-square) = 3.386e-37

Total sequences searched: 3146

Whole sequence top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: