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Classification of phyla is from NCBI page
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Data for CP000931  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000931.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000931_1210 CDS_1480118-1477329 97.3 3.3e-27 1
CP000931_1898 CDS_2291392-2293848 97.0 4.1e-27 1
CP000931_0719 CDS_890984-896269 96.8 4.6e-27 1
CP000931_3967 CDS_4874181-4876838 95.5 1.1e-26 1
CP000931_3753 CDS_4604051-4600440 85.1 9.4e-24 1
CP000931_2542 CDS_3100819-3102558 83.6 2.5e-23 1
CP000931_1507 CDS_1826973-1830515 83.1 3.5e-23 1
CP000931_3030 CDS_3730462-3729152 77.8 1.1e-21 1
CP000931_3387 CDS_4165750-4162586 69.2 3e-19 1
CP000931_0342 CDS_407615-406575 59.4 1.7e-16 1
CP000931_1435 CDS_1742467-1743591 54.1 5.7e-15 1
CP000931_1723 CDS_2079130-2076947 53.3 9.5e-15 1
CP000931_0337 CDS_402619-401249 52.4 1.8e-14 1
CP000931_0239 CDS_288165-286906 52.1 2.1e-14 2
CP000931_1688 CDS_2036919-2040347 47.7 3.7e-13 1
CP000931_0151 CDS_169773-171911 47.4 4.5e-13 1
CP000931_2886 CDS_3542023-3543312 46.1 1e-12 1
CP000931_0929 CDS_1150845-1149577 44.9 2.4e-12 1
CP000931_3920 CDS_4824389-4825645 43.1 7.5e-12 1
CP000931_3655 CDS_4494385-4492991 37.5 2.9e-10 1
CP000931_0407 CDS_479276-477495 33.4 4.3e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000931_1210 1/1 300 365 .. 1 87 [] 97.3 3.3e-27
CP000931_1898 1/1 330 395 .. 1 87 [] 97.0 4.1e-27
CP000931_0719 1/1 1036 1101 .. 1 87 [] 96.8 4.6e-27
CP000931_3967 1/1 382 447 .. 1 87 [] 95.5 1.1e-26
CP000931_3753 1/1 690 755 .. 1 87 [] 85.1 9.4e-24
CP000931_2542 1/1 217 282 .. 1 87 [] 83.6 2.5e-23
CP000931_1507 1/1 496 561 .. 1 87 [] 83.1 3.5e-23
CP000931_3030 1/1 205 271 .. 1 87 [] 77.8 1.1e-21
CP000931_3387 1/1 508 573 .. 1 87 [] 69.2 3e-19
CP000931_0342 1/1 126 191 .. 1 87 [] 59.4 1.7e-16
CP000931_1435 1/1 148 214 .. 1 87 [] 54.1 5.7e-15
CP000931_1723 1/1 498 563 .. 1 87 [] 53.3 9.5e-15
CP000931_0337 1/1 240 302 .. 1 87 [] 52.4 1.8e-14
CP000931_0239 1/2 214 274 .. 1 87 [] 50.5 6e-14
CP000931_1688 1/1 780 846 .. 1 87 [] 47.7 3.7e-13
CP000931_0151 1/1 467 534 .. 1 87 [] 47.4 4.5e-13
CP000931_2886 1/1 225 289 .. 1 87 [] 46.1 1e-12
CP000931_0929 1/1 200 269 .. 1 87 [] 44.9 2.4e-12
CP000931_3920 1/1 220 286 .. 1 87 [] 43.1 7.5e-12
CP000931_3655 1/1 249 316 .. 1 87 [] 37.5 2.9e-10
CP000931_0407 1/1 367 436 .. 1 87 [] 33.4 4.3e-09

Alignments of top-scoring domains:
CP000931_1210: domain 1 of 1, from 300 to 365: score 97.3, E = 3.3e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g+a+ Ll+ t+l + q
CP000931_1 300 IKSEFLANMSHELRTPLNGVIGFAKQLLK---------TPLHSSQ-- 335

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y++ti+r+a ll++ind+Ld+s++eag
CP000931_1 336 ----------QDYIRTIERSATNLLSIINDILDFSKLEAG 365

CP000931_1898: domain 1 of 1, from 330 to 395: score 97.0, E = 4.1e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks flan+sHE+RTPL++I+g++e+L + ++l++ q
CP000931_1 330 AKSSFLANMSHEIRTPLNGIIGMTEILTD---------SKLTAIQ-- 365

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl ti ++++ ll Lind+Ldls+ie+g
CP000931_1 366 ----------KDYLATINSSSQTLLMLINDILDLSKIESG 395

CP000931_0719: domain 1 of 1, from 1036 to 1101: score 96.8, E = 4.6e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+flan+sHE+RTP++aI+g+++l+l tel+ +q
CP000931_0 1036 AKSDFLANMSHEIRTPMNAIIGMSQLCLQ---------TELNRKQ-- 1071

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ y+ +i+r++++ll +ind+Ld+s+ieag
CP000931_0 1072 ----------QNYVLKIDRASKSLLGIINDILDFSKIEAG 1101

CP000931_3967: domain 1 of 1, from 382 to 447: score 95.5, E = 1.1e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks flan+sHE+RTPL++I+g+++++ t+l++ q
CP000931_3 382 AKSSFLANMSHEIRTPLNGIIGMSDIMAG---------TKLTATQ-- 417

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
eyl+ti+ +++ ll Lind+Ldls+ie+g
CP000931_3 418 ----------NEYLQTIETSSQTLLILINDILDLSKIESG 447

CP000931_3753: domain 1 of 1, from 690 to 755: score 85.1, E = 9.4e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHE+RT ++aI+g+++l+++ t l+++q
CP000931_3 690 YKSEFLANMSHEIRTRMNAIIGMLQLAQR---------TSLTPQQ-- 725

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle++ +a++llr+ind+Ld+s+ieag
CP000931_3 726 ----------KDYLEKAGFSAHSLLRIINDILDFSKIEAG 755

CP000931_2542: domain 1 of 1, from 217 to 282: score 83.6, E = 2.5e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++ HELRTPL++++g ael+ + t l++ q
CP000931_2 217 STRDFVAMINHELRTPLNGLLGSAELMSD---------TQLTPHQ-- 252

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++l+t+++++e l+ +indlLdls++ ag
CP000931_2 253 ----------RQLLNTMHQSGELLRVIINDLLDLSKMSAG 282

CP000931_1507: domain 1 of 1, from 496 to 561: score 83.1, E = 3.5e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+R PL+a++g ++l+l+ + l+ eq
CP000931_1 496 AKSRFLATMSHEIRSPLNAVLGSVDLILD---------SRLNKEQ-- 531

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r y +t+++++ +ll+ ind+Ld+s+ieag
CP000931_1 532 ----------RIYANTAKEAGTSLLSTINDILDFSKIEAG 561

CP000931_3030: domain 1 of 1, from 205 to 271: score 77.8, E = 1.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ef+an+sHEL+TPLt+++gy+e+++ + +e +
CP000931_3 205 MRKEFVANVSHELKTPLTVLQGYLEMMQS---------MAEPESPN- 241

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + +l+++ r+++++++lL lsrie
CP000931_3 242 ----------VRAMDQMLQQTTRMRSMVEQLLALSRIEDA 271

CP000931_3387: domain 1 of 1, from 508 to 573: score 69.2, E = 3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL++++g++ lL ++l++ q
CP000931_3 508 AKSLFLATMSHEIRTPLNGLLGTLTLLGH---------SKLPPAQ-- 543

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l + ++ l+ +nd+Ld+sr+e+
CP000931_3 544 ----------MQLLALSQYSGTLLQTVLNDILDFSRLEQR 573

CP000931_0342: domain 1 of 1, from 126 to 191: score 59.4, E = 1.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + +++nl+HE+++PL ++rg+a+lL + el e+++
CP000931_0 126 AAQYLVRNLAHEIKNPLGGLRGAAQLLSR----------ELKEPEL- 161

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+++ i+++a+rl++L+++lL r +
CP000931_0 162 ----------HEFTDLIIEQADRLRNLVDRLLGPQRPTQH 191

CP000931_1435: domain 1 of 1, from 148 to 214: score 54.1, E = 5.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a+l+H+ RTPL+a ++ya+ L + s++ r
CP000931_1 148 ALGKMVATLAHQVRTPLSAALLYASNLAS---------PRISDDAR- 184

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++ + ++ l++++nd+L +++ +++
CP000931_1 185 ----------KRFQGKLVDRLNELEHQVNDMLLMAKGRQQ 214

CP000931_1723: domain 1 of 1, from 498 to 563: score 53.3, E = 9.5e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + + lsHELRTP++++r +e L + ls++
CP000931_1 498 YLENMSSRLSHELRTPVAVVRSSLEHLGL---------QQLSPDS-- 533

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y++++++ ++rl+ ++n++ + +r+ea
CP000931_1 534 ----------RKYVDRAQEGVNRLNMILNNMSEATRLEAS 563

CP000931_0337: domain 1 of 1, from 240 to 302: score 52.4, E = 1.8e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++++++sHELRTPLt +++ + l ++ + ++e+
CP000931_0 240 SQQRLISDISHELRTPLTRLKLSLALSRK--------KGQETAET-- 276

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+i+ ea++l+++i +lL+lsr +
CP000931_0 277 --------------ERIEYEADQLEQMIAELLELSRVKLN 302

CP000931_0239: domain 1 of 2, from 214 to 274: score 50.5, E = 6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++a++sH+LRTPLt Ir+++e++ e e+
CP000931_0 214 DRALLMAGISHDLRTPLTRIRLASEMMVE--------------ED-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + i +++e ++++in++ + r +++
CP000931_0 245 ----------QYLKDGIVNDIEDMDAIINQFISYIRQDQE 274

CP000931_1688: domain 1 of 1, from 780 to 846: score 47.7, E = 3.7e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+fla++ H+L +PL+a r+++ L +++l+ e
CP000931_1 780 SKSRFLAAVGHDLMQPLNAARLFTASLSQ--------YPNLDQEG-- 816

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l+ + ++++ +L+ dlLd+s++++g
CP000931_1 817 ----------KTTLNHVNSSLKIAGELLTDLLDISKLDSG 846

CP000931_0151: domain 1 of 1, from 467 to 534: score 47.4, E = 4.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++e++a+++HE+++P ++I+g+ elL+ el +++ +
CP000931_0 467 ALGELTAGIAHEINNPTAVILGNMELLKYEL-------GDRAVDV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +e +++++ r++ +i+ lL++sr ++
CP000931_0 505 ----------EEEIELVIQQVGRISTIIRSLLQYSRPGEF 534

CP000931_2886: domain 1 of 1, from 225 to 289: score 46.1, E = 1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ s+fl ++sHELRTP+t+++ +a lL+ s+
CP000931_2 225 RESQFLQYASHELRTPITVVKSNAALLEQ----------LISPSN-- 259

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l++i+r+++ + +L + lL l+r e
CP000931_2 260 ----------MPPLQRIIRASNTMHHLTETLLWLTRKELA 289

CP000931_0929: domain 1 of 1, from 200 to 269: score 44.9, E = 2.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++sHE+RTPL+ +++++ lL l+e +++
CP000931_0 200 NQKHLSNAVSHEIRTPLARLKFALALLPQ---------YCLPESDVA 237

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +++l+ ++ +++ +++L+++lL+++ +e++
CP000931_0 238 KR--------QRFLDEMQLDIKEMENLLQELLTYASLETQ 269

CP000931_3920: domain 1 of 1, from 220 to 286: score 43.1, E = 7.5e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ef +sHELRTP+t+++g aelL + + + +
CP000931_3 220 REKEFSHFASHELRTPITVVKGSAELLAK---------IPDQHPLA- 256

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++lr+++ ++ L + +L l +
CP000931_3 257 ----------VNAVKRLLRASDEMQVLTETFLLLGKETID 286

CP000931_3655: domain 1 of 1, from 249 to 316: score 37.5, E = 2.9e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++HE+++PL++ ++++l +++ + ls+ +
CP000931_3 249 AIGQLAMGVAHEINNPLASSTLALDLWERKH-------PQLSDSE-- 286

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ yl++++ +er +++ +lL ++r +g
CP000931_3 287 ----------ANYLSRVRLGIERASSISKELLSYARPASG 316

CP000931_0407: domain 1 of 1, from 367 to 436: score 33.4, E = 4.3e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ ++l+HEL++PL+aIr+y+e l ++++ s+++
CP000931_0 367 LVDKMGSSLAHELNQPLSAIRLYTEGELS-------RRQKGSSQT-- 404

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++l +i+r++ r ++ ++++++l +a
CP000931_0 405 --------DIDQLLGKIRRQVIRVDEVVSRFRQLLHKQAV 436


Histogram of all scores:
score obs exp (one = represents 16 sequences)
----- --- ---
-15 2 0|=
-14 5 0|=
-13 47 3|*==
-12 198 97|======*======
-11 387 507|========================= *
-10 670 940|========================================== *
-9 904 971|========================================================= *
-8 707 727|=============================================*
-7 559 458|============================*======
-6 333 263|================*====
-5 205 144|========*====
-4 108 77|====*==
-3 45 40|==*
-2 29 21|=*
-1 21 11|*=
0 15 5|*
1 3 3|*
2 4 1|*
3 3 0|=
4 1 0|=
5 1 0|=
6 0 0|
7 0 0|
> 8 31 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 317.6074
P(chi-square) = 0

Total sequences searched: 4278

Whole sequence top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 29K


Acknowledgements:

This research is funded by:

Developed by: