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Classification of phyla is from NCBI page
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3 accessions found for Burkholderia cenocepacia MC0-3  

Data for CP000958  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000958.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000958_1271 CDS_1399821-1401140 93.4 3.1e-26 1
CP000958_2288 CDS_2581893-2579050 70.0 1.3e-19 1
CP000958_2662 CDS_2989348-2990901 67.3 7.8e-19 1
CP000958_2146 CDS_2415485-2414343 61.1 4.5e-17 1
CP000958_1296 CDS_1430725-1427063 60.6 6e-17 1
CP000958_2625 CDS_2949511-2948165 59.8 1.1e-16 1
CP000958_0091 CDS_108886-107402 55.9 1.3e-15 1
CP000958_2384 CDS_2688148-2686832 53.1 8.2e-15 1
CP000958_1327 CDS_1473112-1471727 48.3 1.8e-13 1
CP000958_0049 CDS_68170-66803 47.1 4e-13 1
CP000958_2136 CDS_2399622-2402138 42.8 6.8e-12 1
CP000958_1943 CDS_2184265-2185626 40.2 3.6e-11 1
CP000958_3114 CDS_3482042-3479628 38.6 1e-10 1
CP000958_2861 CDS_3208044-3206035 34.4 1.6e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000958_1271 1/1 206 272 .. 1 87 [] 93.4 3.1e-26
CP000958_2288 1/1 678 756 .. 1 87 [] 70.0 1.3e-19
CP000958_2662 1/1 283 348 .. 1 87 [] 67.3 7.8e-19
CP000958_2146 1/1 152 220 .. 1 87 [] 61.1 4.5e-17
CP000958_1296 1/1 848 919 .. 1 87 [] 60.6 6e-17
CP000958_2625 1/1 213 278 .. 1 87 [] 59.8 1.1e-16
CP000958_0091 1/1 240 305 .. 1 87 [] 55.9 1.3e-15
CP000958_2384 1/1 220 278 .. 1 87 [] 53.1 8.2e-15
CP000958_1327 1/1 207 272 .. 1 87 [] 48.3 1.8e-13
CP000958_0049 1/1 235 301 .. 1 87 [] 47.1 4e-13
CP000958_2136 1/1 588 658 .. 1 87 [] 42.8 6.8e-12
CP000958_1943 1/1 234 293 .. 1 87 [] 40.2 3.6e-11
CP000958_3114 1/1 541 613 .. 1 87 [] 38.6 1e-10
CP000958_2861 1/1 420 482 .. 1 81 [. 34.4 1.6e-09

Alignments of top-scoring domains:
CP000958_1271: domain 1 of 1, from 206 to 272: score 93.4, E = 3.1e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt+++g++e+++e +l+ee+r
CP000958_1 206 MRRDFVANVSHELKTPLTVLSGFLETMRE---------LPLNEEDR- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ ++++a r+++++ dlL l+++e +
CP000958_1 243 ----------ARYLDMMEQQASRMRHIVTDLLVLAKLEGE 272

CP000958_2288: domain 1 of 1, from 678 to 756: score 70.0, E = 1.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPLt+I g++++L + g++++ + +++
CP000958_2 678 LRNSLLSAISHDLRTPLTTIVGFSSMLAN-------GRAAAQAGDAA 717

peLR....ledpeyreyletilreaerllrLindlLdlsrieag<-*
++R +++ e+++ i++ea r+ ++ +lLd++r++ag
CP000958_2 718 AAARlaqrE-----GELVDAIHDEALRMTGIVTNLLDMARLQAG 756

CP000958_2662: domain 1 of 1, from 283 to 348: score 67.3, E = 7.8e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ae +l+ ++ +++
CP000958_2 283 LQKRFIADAAHQMKTPLAGLRTQAEFALR---------HPVPPDV-- 318

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ le i ++e+ rL+ +lL l+r+e+
CP000958_2 319 ----------QRSLEQIATSSEQAARLVTQLLALARAENR 348

CP000958_2146: domain 1 of 1, from 152 to 220: score 61.1, E = 4.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++nl+HE+++PL +Irg+a+lL+ el +e+ ++
CP000958_2 152 VNKQLIRNLAHEIKNPLGGIRGAAQLLEFEL-------GERERGEL- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey+++i++e++rl+ L+++lL+ r +
CP000958_2 191 ----------REYTQVIIKESDRLQTLVDRLLEPHRHPHI 220

CP000958_1296: domain 1 of 1, from 848 to 919: score 60.6, E = 6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fla +sHELR PL++I+g a +L + + +++ ++e++
CP000958_1 848 AKDNFLALVSHELRSPLNVISGWAAVLMT-----ARERGVSTDEEMS 889

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ tilr + +Li+dlLd sri +g
CP000958_1 890 ----------QRAVTTILRHCQLQAELIDDLLDVSRISSG 919

CP000958_2625: domain 1 of 1, from 213 to 278: score 59.8, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+a++ a+l + ++ ++
CP000958_2 213 TQKAFVADAAHELRTPLAAVQIQAQLVAR---------AKDDASR-- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re++ +++ + r rL ++lL l+r+e
CP000958_2 249 ----------REAIADLQDGVSRATRLTEQLLALARAEPD 278

CP000958_0091: domain 1 of 1, from 240 to 305: score 55.9, E = 1.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLta++++ae + ++++ q+
CP000958_0 240 AQRKFIADAAHQLRTPLTAVKLHAEQAAV----------ARDPHQT- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++ +a+r rL n+lL l+r+e g
CP000958_0 276 ----------FAAVRELRAAADRAVRLSNQLLSLARAEPG 305

CP000958_2384: domain 1 of 1, from 220 to 278: score 53.1, E = 8.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+LRTPL+ +r+ ae++ +
CP000958_2 220 DRAVMLAGVAHDLRTPLARMRLRAEMMDD------------------ 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + + r++++++++++++L ++ +a
CP000958_2 249 ----------ARLRDGVVRDVDSMSHIVDQFLVFAHGGAD 278

CP000958_1327: domain 1 of 1, from 207 to 272: score 48.3, E = 1.8e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++ ++sHEL+TPL+ + + + lL + ++ +
CP000958_1 207 QQREMMHGISHELKTPLARLEFGLALLAD---------ADETGRM-- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re + ++r+++ l++L+ +lL++ r+e+g
CP000958_1 243 ----------RERRDALRRDVRELDELVTELLTIGRLEQG 272

CP000958_0049: domain 1 of 1, from 235 to 301: score 47.1, E = 4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++H+LRTP++++ + ++ ++ ++ ++
CP000958_0 235 TQRRFIADAAHQLRTPIAVLDTQIQYAQQ---------RGNDDREL- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l++++r+++ + + + lL l+ +ea
CP000958_0 272 ----------AAVLDSMQRSSRKMADVTDKLLLLAHAEAT 301

CP000958_2136: domain 1 of 1, from 588 to 658: score 42.8, E = 6.8e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++++HEL++PL+aI y++ l+ l +++ ++e++
CP000958_2 588 TMGEMASSIAHELNQPLAAINNYCSGTLA-----LVKSGRGTPETL- 628

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le+ ++a r ++ +++++ + ++
CP000958_2 629 ----------QPALEKTAQQALRAGMIVKRIREFVKRSEP 658

CP000958_1943: domain 1 of 1, from 234 to 293: score 40.2, E = 3.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ +
CP000958_1 234 DRALMLAGISHDLRTPLARLRLETEMSPSD----------------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + +++e+++r+i + d++r +
CP000958_1 264 ----------QATKDAMVDDIEQMDRIIAAFIDYARPSQR 293

CP000958_3114: domain 1 of 1, from 541 to 613: score 38.6, E = 1e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l +++l +++ +
CP000958_3 541 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL------SDKLAPPD-A 580

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ L ++ i +++ + r+++d+++++r
CP000958_3 581 DVL-------KRGATMIVNQVAAMKRMVDDFREYARTPPA 613

CP000958_2861: domain 1 of 1, from 420 to 482: score 34.4, E = 1.6e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+a+r +++ + +++e+ ++
CP000958_2 420 ALGQMAAGITHELNQPLAALRSFSDNTRV--------LLDRGEQAAA 458

peLRledpeyreyletilreaerllrLindlLdl<-*
re le i +er+ ++ n+l +
CP000958_2 459 ----------RENLEAIAALTERMGKITNQLKLF 482


Histogram of all scores:
score obs exp (one = represents 11 sequences)
----- --- ---
-14 9 0|=
-13 29 2|*==
-12 109 72|======*===
-11 277 374|========================== *
-10 523 694|================================================ *
-9 622 717|========================================================= *
-8 569 537|================================================*===
-7 435 338|==============================*=========
-6 251 194|=================*=====
-5 146 106|=========*====
-4 80 57|=====*==
-3 38 30|==*=
-2 30 15|=*=
-1 12 8|*=
0 6 4|*
1 5 2|*
2 1 1|*
3 0 0|
> 4 18 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 184.5622
P(chi-square) = 1.171e-33

Total sequences searched: 3160

Whole sequence top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: