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Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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76 projects found  

3 accessions found for Burkholderia cenocepacia MC0-3  

Data for CP000959  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000959.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000959_1030 CDS_1156442-1159450 86.2 3e-24 1
CP000959_1434 CDS_1648608-1645024 84.4 1e-23 1
CP000959_1490 CDS_1711310-1707597 83.1 2.2e-23 1
CP000959_2448 CDS_2821096-2817674 81.6 6.2e-23 1
CP000959_1486 CDS_1699562-1702924 74.7 5.6e-21 1
CP000959_2758 CDS_3174355-3172385 73.8 9.7e-21 1
CP000959_0043 CDS_51280-52764 67.0 8.3e-19 1
CP000959_0651 CDS_757332-755908 65.9 1.6e-18 1
CP000959_1036 CDS_1177437-1180472 65.8 1.8e-18 1
CP000959_0084 CDS_98258-96834 61.0 4.1e-17 1
CP000959_0917 CDS_1048070-1049479 59.5 1.1e-16 1
CP000959_2136 CDS_2466300-2467430 59.1 1.4e-16 1
CP000959_2272 CDS_2626418-2627869 57.5 4.1e-16 1
CP000959_2148 CDS_2488915-2487548 55.1 1.9e-15 1
CP000959_0958 CDS_1087987-1089819 52.3 1.2e-14 1
CP000959_1173 CDS_1339658-1340743 44.7 1.7e-12 1
CP000959_0486 CDS_577384-578163 39.1 6.5e-11 1
CP000959_1028 CDS_1155119-1153683 36.0 5e-10 1
CP000959_1878 CDS_2165260-2167158 33.6 2.5e-09 1
CP000959_0742 CDS_858524-859948 30.6 1.7e-08 1
CP000959_0889 CDS_1020017-1018665 28.6 6.1e-08 1
CP000959_1716 CDS_1961006-1959123 26.9 1.9e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000959_1030 1/1 515 580 .. 1 87 [] 86.2 3e-24
CP000959_1434 1/1 601 666 .. 1 87 [] 84.4 1e-23
CP000959_1490 1/1 643 708 .. 1 87 [] 83.1 2.2e-23
CP000959_2448 1/1 686 753 .. 1 87 [] 81.6 6.2e-23
CP000959_1486 1/1 535 600 .. 1 87 [] 74.7 5.6e-21
CP000959_2758 1/1 275 340 .. 1 87 [] 73.8 9.7e-21
CP000959_0043 1/1 234 301 .. 1 87 [] 67.0 8.3e-19
CP000959_0651 1/1 242 308 .. 1 87 [] 65.9 1.6e-18
CP000959_1036 1/1 525 590 .. 1 87 [] 65.8 1.8e-18
CP000959_0084 1/1 244 309 .. 1 87 [] 61.0 4.1e-17
CP000959_0917 1/1 247 313 .. 1 87 [] 59.5 1.1e-16
CP000959_2136 1/1 161 226 .. 1 87 [] 59.1 1.4e-16
CP000959_2272 1/1 255 320 .. 1 87 [] 57.5 4.1e-16
CP000959_2148 1/1 230 295 .. 1 87 [] 55.1 1.9e-15
CP000959_0958 1/1 235 300 .. 1 87 [] 52.3 1.2e-14
CP000959_1173 1/1 134 198 .. 1 87 [] 44.7 1.7e-12
CP000959_0486 1/1 28 95 .. 1 87 [] 39.1 6.5e-11
CP000959_1028 1/1 254 322 .. 1 87 [] 36.0 5e-10
CP000959_1878 1/1 404 474 .. 1 87 [] 33.6 2.5e-09
CP000959_0742 1/1 241 298 .. 1 79 [. 30.6 1.7e-08
CP000959_0889 1/1 247 305 .. 1 87 [] 28.6 6.1e-08
CP000959_1716 1/1 394 462 .. 1 87 [] 26.9 1.9e-07

Alignments of top-scoring domains:
CP000959_1030: domain 1 of 1, from 515 to 580: score 86.2, E = 3e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL+aI+g++el+ + ++l + q
CP000959_1 515 AKSAFLATMSHEIRTPLNAILGNLELIGR---------EPLADTQ-- 550

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re l+t++ ++ ll+Li+d+Ldls+ieag
CP000959_1 551 ----------RERLQTVEGASSVLLNLISDILDLSKIEAG 580

CP000959_1434: domain 1 of 1, from 601 to 666: score 84.4, E = 1e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+fla++sHE+RTP+++I+g++elL+ + ls q
CP000959_1 601 SKSRFLATMSHEIRTPMNGIIGMLELLRH---------ESLSTNQ-- 636

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ i ++a l ++++d+Ld+s+i+ag
CP000959_1 637 ----------QRMLHMIGESAMTLMQILDDVLDFSKIDAG 666

CP000959_1490: domain 1 of 1, from 643 to 708: score 83.1, E = 2.2e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +fla++sHE+RTP+++I g++elL+ + ls +q
CP000959_1 643 SKARFLATMSHEIRTPMNGIVGMLELLRH---------ESLSLKQ-- 678

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ i ++a l ++++d+Ld+s+i+ag
CP000959_1 679 ----------QRMLHMIGESAMTLMQILDDVLDFSKIDAG 708

CP000959_2448: domain 1 of 1, from 686 to 753: score 81.6, E = 6.2e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+ +++lsHELRTPL++I+gya+lLl +el++
CP000959_2 686 AKSRYVSGLSHELRTPLNSILGYAQLLLQ-------AKEELTPMR-- 723

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ti+r++e+ll+L++ lLd++rieag
CP000959_2 724 ----------YNAVRTIHRSGEHLLALVDGLLDIARIEAG 753

CP000959_1486: domain 1 of 1, from 535 to 600: score 74.7, E = 5.6e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+ fla++sHE+RTPL++ +g++elL + l+ eq
CP000959_1 535 EKGMFLATMSHEIRTPLHGALGNLELLSR---------MGLTQEQ-- 570

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l +++++ +ll+Lin +Ldlsrieag
CP000959_1 571 ----------RSRLLIAQDSFGSLLSLINGVLDLSRIEAG 600

CP000959_2758: domain 1 of 1, from 275 to 340: score 73.8, E = 9.7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+e+la++sHELRTPL++I g ae+L++ ++ +
CP000959_2 275 LKDELLATVSHELRTPLNVIYGWAEVLRN---------ADGQDFA-- 310

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ i+r+a++l++++ dlLd s + +g
CP000959_2 311 ----------QQAVDAIDRSARSLSHMVADLLDASSLATG 340

CP000959_0043: domain 1 of 1, from 234 to 301: score 67.0, E = 8.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f a+++HELRTP++ ++g ++++l+ + ++s + +
CP000959_0 234 RLEAFNADVAHELRTPISILIGQTQVALT--------SRDRSVDRM- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l++ l+e erl+ +ind+L lsr + g
CP000959_0 272 ----------RQTLQSNLEEFERLRVIINDMLFLSRSDRG 301

CP000959_0651: domain 1 of 1, from 242 to 308: score 65.9, E = 1.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f +nl+H++RTPLt ++++a++ l +++s+++
CP000959_0 242 RLSQFSSNLAHDMRTPLTNLQAAAQVVLS---------QPRSADE-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr +e+ ++e +rl+r+i+d+L l+r e+
CP000959_0 278 ---------YRIVIESSIDEYQRLSRMIDDMLFLARSEQA 308

CP000959_1036: domain 1 of 1, from 525 to 590: score 65.8, E = 1.8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL+a++g++elL + ++ +
CP000959_1 525 AKSTFLATISHEIRTPLNAMLGNLELLDK---------APDRNRE-- 560

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l+ + ++a+ ll+++n++Ld+++iea
CP000959_1 561 ----------KSRLHAVTSAARMLLDMLNNVLDMTKIEAD 590

CP000959_0084: domain 1 of 1, from 244 to 309: score 61.0, E = 4.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+L+TPL+a+++ +el+l+ ++ +
CP000959_0 244 ARRRFFADAAHQLKTPLAAVQAGVELALR---------PDEQPRA-- 279

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++ ++++ +++++lL lsr+++
CP000959_0 280 ----------NVHLRRANGAVRQAAKIVQQLLSLSRLDSD 309

CP000959_0917: domain 1 of 1, from 247 to 313: score 59.5, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f ++l+H++RTPL+ ++ +++ l +++ ++
CP000959_0 247 RLSQFSSDLAHDMRTPLANVISSSQITLS---------RARTTDE-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++e+ ++e erl+r+i+++L l+r ++
CP000959_0 283 ---------YEALIESNIEECERLQRMIENMLFLARTDNA 313

CP000959_2136: domain 1 of 1, from 161 to 226: score 59.1, E = 1.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++ ++sHELRTPL+ +r+++e+L+e + s+ +
CP000959_2 161 AQRDLTNGISHELRTPLARVRFALEMLRE----------PGSAAE-- 195

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ +l++i +++ l++Li+ L+++r+e
CP000959_2 196 ---------YQGALDSIAQDVTELEELIDMSLTYARLEYS 226

CP000959_2272: domain 1 of 1, from 255 to 320: score 57.5, E = 4.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + +l HE++ PL+aI+g+aelL+e +++ r
CP000959_2 255 YVETYIHTLTHEMKSPLAAISGAAELLQE----------DMPVANR- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+++e i+r+a rl+++i+ lL l+ e+
CP000959_2 291 ----------RRFTENIRRQAGRLEQMIRKLLALAEVEQK 320

CP000959_2148: domain 1 of 1, from 230 to 295: score 55.1, E = 1.9e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++HELRTP+ +++ ++lL++ ++++e+r
CP000959_2 230 LQRHFIADAAHELRTPIMGLSIQSQLLRR----------AATAEER- 265

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l i+ + rl +L ++lL+l+r+e
CP000959_2 266 ----------EHILAQIQAGTTRLGHLAEQLLTLARLEPD 295

CP000959_0958: domain 1 of 1, from 235 to 300: score 52.3, E = 1.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl ++sHELRTPL aI g +e+Ll+ ++s+
CP000959_0 235 AKNAFLGMVSHELRTPLQAICGSIEILLA---------RPQSDAN-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++a +l++L+ dl d+ ++++
CP000959_0 271 ----------LKTIRRLQNSALSLEALVKDLTDYIKLRST 300

CP000959_1173: domain 1 of 1, from 134 to 198: score 44.7, E = 1.7e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ + a+++HELRTP+t++rg ++ L e + ++ +
CP000959_1 134 EQTFWNAAIAHELRTPVTVLRGRLQGLAE---------GVFTPSD-- 169

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++l ++e l rLi+dl+ s +++g
CP000959_1 170 -----------ALYRSLLVQVEGLTRLIEDLRVVSLADSG 198

CP000959_0486: domain 1 of 1, from 28 to 95: score 39.1, E = 6.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ l+++sH+LR PL+a+ a +L+++l +++++
CP000959_0 28 LRDQALSTASHDLRSPLNAMHSWAYVLERQL-------ANADPNL-- 65

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ +++ +Li+ +Ld r+e+
CP000959_0 66 ----------QRALAGIRTGIDQQVALIDGVLDAPRAETR 95

CP000959_1028: domain 1 of 1, from 254 to 322: score 36.0, E = 5e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HEL++PL+aI +++ ++++ l +l++e
CP000959_1 254 TLGEMAAGIAHELNQPLAAIVAHTRAAERML--------DLPAER-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++r++l++ +a+r ++++ L + ag
CP000959_1 291 -------DGVRRALQSSVAQAKRAATILDR-LRGAMTSAG 322

CP000959_1878: domain 1 of 1, from 404 to 474: score 33.6, E = 2.5e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++a+++HE +PL+aI ++ e+ + + ++s+++
CP000959_1 404 MLGELAASIAHEVTQPLAAIVTAGEAGMR--------WIKRSPPD-- 440

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e++ +l + ++a+r + i +++ +++ + +
CP000959_1 441 ------FTEVQYALGQMTHDARRATQVIHQIRSMAQRRDP 474

CP000959_0742: domain 1 of 1, from 241 to 298: score 30.6, E = 1.7e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H++RTPL+ + + +elL + ++ +
CP000959_0 241 AMQRFIADAAHQMRTPLARLDAQIELLDG---------ESDPARH-- 276

peLRledpeyreyletilreaerllrLindlL<-*
+ l+ ++ + rL +lL
CP000959_0 277 ----------AARLDALRATSSDVGRLTGQLL 298

CP000959_0889: domain 1 of 1, from 247 to 305: score 28.6, E = 6.1e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++fla+++HEL TPLt +rg +el ++ s +
CP000959_0 247 VQQQFLAAAAHELQTPLTLVRGQIEL--Q---------PDISQKA-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+lre++ + r++ +lL l+ +
CP000959_0 281 ---------------LLLREIDLMARQVKQLLHLAEVSEA 305

CP000959_1716: domain 1 of 1, from 394 to 462: score 26.9, E = 1.9e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++a+l HEL++PL aIr++++ ++++++ ++++
CP000959_1 394 VLGQMAAGLTHELNQPLVAIRTLCDNARTFFE------RGQPAPA-- 432

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le++ + ++ + L +l +++r
CP000959_1 433 ----------LANLERVGKLVDGMAVLTGELKTFARKPDV 462


Histogram of all scores:
score obs exp (one = represents 10 sequences)
----- --- ---
-14 9 0|=
-13 23 2|*==
-12 81 63|======*==
-11 228 331|======================= *
-10 468 614|=============================================== *
-9 555 634|======================================================== *
-8 520 475|===============================================*====
-7 381 299|=============================*=========
-6 214 172|=================*====
-5 138 94|=========*====
-4 68 50|====*==
-3 38 26|==*=
-2 17 14|=*
-1 10 7|*
0 6 3|*
1 5 1|*
2 3 1|*
3 1 0|=
4 0 0|
5 0 0|
> 6 30 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 150.5635
P(chi-square) = 1.143e-26

Total sequences searched: 2795

Whole sequence top hits:
tophits_s report:
Total hits: 22
Satisfying E cutoff: 22
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 22
Satisfying E cutoff: 22
Total memory: 29K


Acknowledgements:

This research is funded by:

Developed by: