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Classification of phyla is from NCBI page
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264 projects found  

3 accessions found for Klebsiella pneumoniae 342  

Data for CP000964  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000964.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000964_3026 CDS_3140023-3142716 106.3 1.2e-29 1
CP000964_0978 CDS_1009941-1007191 96.8 5.9e-27 1
CP000964_4260 CDS_4381526-4380231 91.9 1.4e-25 1
CP000964_0624 CDS_651183-647941 83.1 4.3e-23 1
CP000964_1480 CDS_1535924-1538764 79.4 5e-22 1
CP000964_0494 CDS_524129-526468 78.8 7.1e-22 1
CP000964_3605 CDS_3714507-3713035 77.1 2.2e-21 1
CP000964_1216 CDS_1260793-1262232 76.9 2.5e-21 1
CP000964_5322 CDS_5528521-5529894 66.1 2.9e-18 1
CP000964_4666 CDS_4814035-4812611 64.2 1e-17 1
CP000964_1601 CDS_1671727-1670225 63.0 2.2e-17 1
CP000964_5171 CDS_5352855-5351461 62.4 3.3e-17 1
CP000964_5367 CDS_5571908-5572957 60.3 1.3e-16 1
CP000964_4798 CDS_4950278-4948845 60.2 1.4e-16 1
CP000964_3783 CDS_3900611-3903298 59.2 2.6e-16 1
CP000964_0670 CDS_693186-691837 56.3 1.8e-15 1
CP000964_0339 CDS_377409-378764 53.8 8.6e-15 1
CP000964_1610 CDS_1686106-1684250 50.2 9.5e-14 1
CP000964_3700 CDS_3812225-3813322 46.4 1.1e-12 1
CP000964_2881 CDS_2987284-2988585 44.0 5.4e-12 1
CP000964_2611 CDS_2728868-2730064 43.4 7.6e-12 1
CP000964_5064 CDS_5231503-5229218 41.0 3.8e-11 1
CP000964_2495 CDS_2606133-2607476 32.9 7.2e-09 1
CP000964_3354 CDS_3433778-3435244 26.8 3.8e-07 2

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000964_3026 1/1 267 332 .. 1 87 [] 106.3 1.2e-29
CP000964_0978 1/1 292 357 .. 1 87 [] 96.8 5.9e-27
CP000964_4260 1/1 203 269 .. 1 87 [] 91.9 1.4e-25
CP000964_0624 1/1 596 662 .. 1 87 [] 83.1 4.3e-23
CP000964_1480 1/1 467 532 .. 1 87 [] 79.4 5e-22
CP000964_0494 1/1 282 347 .. 1 87 [] 78.8 7.1e-22
CP000964_3605 1/1 268 336 .. 1 87 [] 77.1 2.2e-21
CP000964_1216 1/1 255 323 .. 1 87 [] 76.9 2.5e-21
CP000964_5322 1/1 238 300 .. 1 87 [] 66.1 2.9e-18
CP000964_4666 1/1 255 320 .. 1 87 [] 64.2 1e-17
CP000964_1601 1/1 273 337 .. 1 87 [] 63.0 2.2e-17
CP000964_5171 1/1 241 307 .. 1 87 [] 62.4 3.3e-17
CP000964_5367 1/1 129 186 .. 1 79 [. 60.3 1.3e-16
CP000964_4798 1/1 258 324 .. 1 87 [] 60.2 1.4e-16
CP000964_3783 1/1 663 730 .. 1 87 [] 59.2 2.6e-16
CP000964_0670 1/1 236 302 .. 1 87 [] 56.3 1.8e-15
CP000964_0339 1/1 233 293 .. 1 87 [] 53.8 8.6e-15
CP000964_1610 1/1 398 463 .. 1 87 [] 50.2 9.5e-14
CP000964_3700 1/1 143 203 .. 1 87 [] 46.4 1.1e-12
CP000964_2881 1/1 211 271 .. 1 87 [] 44.0 5.4e-12
CP000964_2611 1/1 170 233 .. 1 87 [] 43.4 7.6e-12
CP000964_5064 1/1 402 464 .. 1 87 [] 41.0 3.8e-11
CP000964_2495 1/1 226 284 .. 1 87 [] 32.9 7.2e-09

Alignments of top-scoring domains:
CP000964_3026: domain 1 of 1, from 267 to 332: score 106.3, E = 1.2e-29
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks flan+sHE+RTP+++I+g+++l+l+ t+l++eq
CP000964_3 267 AKSAFLANMSHEIRTPMNGILGMTQLCLD---------TPLTAEQ-- 302

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
reyl+ + ++a++ll++ind+Ld+srie+g
CP000964_3 303 ----------REYLSLVMSSAQSLLHIINDILDFSRIESG 332

CP000964_0978: domain 1 of 1, from 292 to 357: score 96.8, E = 5.9e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ t+l++ q
CP000964_0 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TDLNATQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l ti+r+a+ ll++ind+Ld+s++eag
CP000964_0 328 ----------RDHLTTIERSANNLLAIINDVLDFSKLEAG 357

CP000964_4260: domain 1 of 1, from 203 to 269: score 91.9, E = 1.4e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e+++e + l +r
CP000964_4 203 ARRNFFANVSHELRTPLTVLQGYLEMMQE---------QVLEGATR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+lsriea
CP000964_4 240 ----------EKALHTMREQTQRMEGLVKQLLTLSRIEAA 269

CP000964_0624: domain 1 of 1, from 596 to 662: score 83.1, E = 4.3e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHELRTP++aI g++elL + +el+ qr
CP000964_0 596 AKSRFLASMSHELRTPVSAIVGFLELLAK---------PELNGGQR- 632

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e + + a+ ll Li ++Ld+ +ie+g
CP000964_0 633 ----------KEAIELAGSTAQTLLGLIGNILDIDKIESG 662

CP000964_1480: domain 1 of 1, from 467 to 532: score 79.4, E = 5e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ +l+
CP000964_1 467 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KALPKGV-- 502

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP000964_1 503 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 532

CP000964_0494: domain 1 of 1, from 282 to 347: score 78.8, E = 7.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP000964_0 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTSEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP000964_0 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP000964_3605: domain 1 of 1, from 268 to 336: score 77.1, E = 2.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef+an+sH+LRTPLt+++gy+e+L +d+ l++e+r
CP000964_3 268 QRREFVANISHDLRTPLTSLLGYLETLTL-------KDERLTAEER- 306

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+yl ++lr+++ ++L ++l +l+r+e+g
CP000964_3 307 ----------RQYLTIALRQGNKVRHLSQQLFELARLEHG 336

CP000964_1216: domain 1 of 1, from 255 to 323: score 76.9, E = 2.5e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP000964_1 255 QRHQFLRHLSHELKTPLASMREGTELLADRVA------GPLTPEQ-- 293

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e+++++++ l++Li++lLd+ r +a
CP000964_1 294 ----------QEIVEILDSSSRNLQKLIEQLLDYNRKQAD 323

CP000964_5322: domain 1 of 1, from 238 to 300: score 66.1, E = 2.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP000964_5 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr +a
CP000964_5 274 -------------LERIETEAHRLDSMINDLLVMSRNQAK 300

CP000964_4666: domain 1 of 1, from 255 to 320: score 64.2, E = 1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + + +l HEL+ PL+aIrg+ae+L+e ++ ++
CP000964_4 255 AIENYVYDLTHELKSPLAAIRGAAEILRE---------GPPPAVA-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r++ L+++lL+ +r+e+
CP000964_4 291 ----------ARFTDNILAQNTRMQLLVERLLQQARLESR 320

CP000964_1601: domain 1 of 1, from 273 to 337: score 63.0, E = 2.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a++sHELRTPL+++rg +e++++++ ++e
CP000964_1 273 MRRDLMADISHELRTPLAVLRGELEAIQDGV-------RRFTPES-- 310

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP000964_1 311 -------------IPSLQAEVATLTKLVDDLHQLSMSDEG 337

CP000964_5171: domain 1 of 1, from 241 to 307: score 62.4, E = 3.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +t+ + e
CP000964_5 241 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RTPPGGEA-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l r +
CP000964_5 278 ----------QQLAQVMAKEADRLNRVVSELLELVRPAHL 307

CP000964_5367: domain 1 of 1, from 129 to 186: score 60.3, E = 1.3e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP000964_5 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP000964_5 165 ----------TEYTKVIIEQADRLRNLVDRLL 186

CP000964_4798: domain 1 of 1, from 258 to 324: score 60.2, E = 1.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t + + +e++l + +s +++
CP000964_4 258 RQSNFSADIAHEIRTPITNLVTQTEIALS---------QSRSQQEL- 294

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l + l+e r++r+++d+L l++++++
CP000964_4 295 ----------EEVLYSNLEEFSRMSRMVSDMLFLAQADNN 324

CP000964_3783: domain 1 of 1, from 663 to 730: score 59.2, E = 2.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CP000964_3 663 LRNSLLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSKH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i++ + rL+n+lLd++ri++g
CP000964_3 701 ----------APQANEIRQHVLNTTRLVNNLLDMARIQSG 730

CP000964_0670: domain 1 of 1, from 236 to 302: score 56.3, E = 1.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PL+a++ +++++ + ++e r
CP000964_0 236 RERRFTSDAAHELRSPLAALKVQTDVAQL---------SMDDAEGR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CP000964_0 273 ----------EKALAQLHQGIDRATRLVDQLLTLSRLDSL 302

CP000964_0339: domain 1 of 1, from 233 to 293: score 53.8, E = 8.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP000964_0 233 DRTLLMAGVSHDLRTPLTRIRLATEMMGE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP000964_0 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP000964_1610: domain 1 of 1, from 398 to 463: score 50.2, E = 9.5e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +++HE+RTPL++I++++e L+ +++s+ q
CP000964_1 398 HQRQFMGMVAHEFRTPLAVIQAALENLRL---------SAASASQ-- 433

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++i r+a rl +L ++ L +r+ +
CP000964_1 434 ----------EARFDRIGRAATRLVQLTDNCLADARLASH 463

CP000964_3700: domain 1 of 1, from 143 to 203: score 46.4, E = 1.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL+++r+++elL + +
CP000964_3 143 RERLFTADVAHELRTPLAGLRLHLELLSK----------VHGVGV-- 177

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ ++++ i++lL+l+r ++
CP000964_3 178 --------------DPLIQRLDQMTTSISQLLQLARVGQS 203

CP000964_2881: domain 1 of 1, from 211 to 271: score 44.0, E = 5.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ ++ l+e +
CP000964_2 211 SKKQLIDGIAHELRTPLVRLRYRLEMSEN-----------LTEAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP000964_2 245 -------------SQALNRDIGQLEALIEELLTYARLDRP 271

CP000964_2611: domain 1 of 1, from 170 to 233: score 43.4, E = 7.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +a ++HELR PLta +g ++ +l++++ ++s+eq
CP000964_2 170 LRTSHVA-MAHELRSPLTAAIGRLQGMLDGVF-------DASPEQ-- 206

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l + +++++l+rL ++l ls +ag
CP000964_2 207 -------------LAMVMKQLQHLNRLTDELHLLSLSDAG 233

CP000964_5064: domain 1 of 1, from 402 to 464: score 41.0, E = 3.8e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + ++++++
CP000964_5 402 AVGQLTGGLAHDFNNLLAVIIGSLELVEP---------DARDAPR-- 437

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++l++aer L ++lL +sr +a
CP000964_5 438 -------------LSRALKAAERGALLTQRLLAFSRKQAL 464

CP000964_2495: domain 1 of 1, from 226 to 284: score 32.9, E = 7.2e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + la++sH+L TP+t +++ +e++
CP000964_2 226 ERARILAAISHDLQTPITRMKLRVEMADQ------------------ 254

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ +++l++++ + rL+++ ++r ++
CP000964_2 255 ----------PELRDKLLQDLDNMTRLVREGIAFARTSQP 284


Histogram of all scores:
score obs exp (one = represents 18 sequences)
----- --- ---
-15 8 0|=
-14 29 0|==
-13 115 4|*======
-12 244 123|======*=======
-11 496 643|============================ *
-10 943 1193|===================================================== *
-9 1021 1231|========================================================= *
-8 940 922|===================================================*=
-7 659 581|================================*====
-6 416 334|==================*=====
-5 231 183|==========*==
-4 139 98|=====*==
-3 65 51|==*=
-2 35 27|=*
-1 28 14|*=
0 13 7|*
1 8 3|*
2 5 2|*
3 4 1|*
> 4 26 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 321.1424
P(chi-square) = 0

Total sequences searched: 5425

Whole sequence top hits:
tophits_s report:
Total hits: 24
Satisfying E cutoff: 24
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 23
Satisfying E cutoff: 23
Total memory: 30K


Acknowledgements:

This research is funded by:

Developed by: