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Thermotogae
Classification of phyla is from NCBI page
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25 projects found  

1 accessions found for Methylacidiphilum infernorum V4  

Data for CP000975  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP000975.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP000975_0155 CDS_159592-158273 65.6 1.9e-18 1
CP000975_0753 CDS_722368-725076 59.5 9.7e-17 1
CP000975_0764 CDS_732549-734090 56.3 7.8e-16 2
CP000975_0599 CDS_585220-583835 42.5 6.4e-12 2
CP000975_1131 CDS_1070337-1071794 39.6 4.3e-11 1
CP000975_2093 CDS_1951498-1950302 36.4 3.4e-10 1
CP000975_1018 CDS_974944-973496 29.9 2.4e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP000975_0155 1/1 203 270 .. 1 87 [] 65.6 1.9e-18
CP000975_0753 1/1 666 734 .. 1 87 [] 59.5 9.7e-17
CP000975_0764 1/2 295 361 .. 1 87 [] 50.5 3.5e-14
CP000975_0599 2/2 229 295 .. 1 87 [] 41.2 1.5e-11
CP000975_1131 1/1 274 329 .. 1 78 [. 39.6 4.3e-11
CP000975_2093 1/1 153 221 .. 1 79 [. 36.4 3.4e-10
CP000975_1018 1/1 265 331 .. 1 87 [] 29.9 2.4e-08

Alignments of top-scoring domains:
CP000975_0155: domain 1 of 1, from 203 to 270: score 65.6, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+ ef+ n+sHELRTPL+ +gy+e+L ++ + ls ++
CP000975_0 203 ARKEFVINVSHELRTPLAIFKGYVETLTDN--------PRLSKSEV- 240

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ e++++ +rl++Li+dlL l+++e+
CP000975_0 241 ----------KRIYEILKKHCQRLSSLIEDLLLLAKLESR 270

CP000975_0753: domain 1 of 1, from 666 to 734: score 59.5, E = 9.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +l ++sHE++TP+++I +++e L + + ++++
CP000975_0 666 LSRTLLNSISHEMKTPIAVITTAIESLSK------EDQSIKTADR-- 704

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++e i++++ rl+r++++lLd++rie+g
CP000975_0 705 ----------AQLIEEIRSATLRLNRIVRNLLDMARIESG 734

CP000975_0764: domain 1 of 2, from 295 to 361: score 50.5, E = 3.5e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ ++a ++HE+R+PLt+I ++++ L+ + +++
CP000975_0 295 SLGLLAAEIAHEIRNPLTVIHMLIHSLKS--------RIQCDPVS-- 331

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ le++++ +++r+++++L l ++ ++
CP000975_0 332 ----------QKDLEVLEKKMVQMNRIVDQVLVLGKAPQP 361

CP000975_0599: domain 2 of 2, from 229 to 295: score 41.2, E = 1.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +++a++sHEL+TPLt ++ +e +l +++ + ++
CP000975_0 229 REIRLTADASHELKTPLTILKNELESALQ--------RSDVDLQT-- 265

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + ++++++ l++L + lL ls ++
CP000975_0 266 ----------EKTFLNLYEQVQTLSSLTQTLLFLSNLDRD 295

CP000975_1131: domain 1 of 1, from 274 to 329: score 39.6, E = 4.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +a+l HELR+PL++I++ +e +l + ++ + e
CP000975_1 274 TLGKVAATLTHELRNPLATIQLEVENALQ-------SKDKGNKEP-- 311

peLRledpeyreyletilreaerllrLindl<-*
le +++++er+ +L++ +
CP000975_1 312 -------------LECVQEQVERMKKLLDSI 329

CP000975_2093: domain 1 of 1, from 153 to 221: score 36.4, E = 3.4e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkv.lagdtelseeqr
++ ++a+++HEL +P++a+ + +l+++++ k+ +++ + +++++
CP000975_2 153 LLTMLAAGVAHELGNPINALGIHFQLIEKKYKKLlQQKNGQIGDKEI 199

lpeLRledpeyreyletilreaerllrLindlL<-*
+ + i++e++rl+ +in++L
CP000975_2 200 -----------ENSFAAIRSEIRRLDGIINQFL 221

CP000975_1018: domain 1 of 1, from 265 to 331: score 29.9, E = 2.4e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + +a+++H +++PL++Ir++ae+ l +++l +
CP000975_1 265 SIEATAAAVAHGIKNPLSSIRALAEVSLL--------EENLEQST-- 301

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r ++ il e++ l++ in lL +++ +
CP000975_1 302 ----------RATFKEILIETDILNKRINHLLSYTKPSVP 331


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-15 8 0|=
-14 42 0|======
-13 108 1|*=============
-12 199 56|======*==================
-11 293 293|====================================*
-10 429 543|====================================================== *
-9 450 561|========================================================= *
-8 352 420|============================================ *
-7 243 264|=============================== *
-6 141 152|==================*
-5 90 83|==========*=
-4 46 44|=====*
-3 32 23|==*=
-2 19 12|=*=
-1 5 6|*
0 2 3|*
1 1 1|*
2 2 0|=
3 1 0|=
4 0 0|
> 5 9 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 426.7626
P(chi-square) = 0

Total sequences searched: 2472

Whole sequence top hits:
tophits_s report:
Total hits: 7
Satisfying E cutoff: 7
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 7
Satisfying E cutoff: 7
Total memory: 23K


Acknowledgements:

This research is funded by:

Developed by: