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Classification of phyla is from NCBI page
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76 projects found  

4 accessions found for Burkholderia phymatum STM815  

Data for CP001043  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001043.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001043_0132 CDS_144107-149002 101.7 1.4e-28 2
CP001043_0130 CDS_140895-142343 93.1 3.5e-26 1
CP001043_0354 CDS_402606-407063 91.8 8.4e-26 1
CP001043_0880 CDS_992153-993466 87.0 1.9e-24 1
CP001043_2035 CDS_2306427-2303578 80.0 1.9e-22 1
CP001043_0131 CDS_142340-143983 72.7 2.3e-20 1
CP001043_0433 CDS_499097-497550 66.0 1.8e-18 1
CP001043_3029 CDS_3433753-3435252 60.4 6.6e-17 1
CP001043_1465 CDS_1671732-1670590 60.0 8.8e-17 1
CP001043_1176 CDS_1330926-1332368 55.3 1.8e-15 1
CP001043_0637 CDS_726816-728279 51.8 1.9e-14 1
CP001043_0984 CDS_1110609-1112600 51.6 2.1e-14 1
CP001043_2137 CDS_2422428-2421088 50.3 4.9e-14 1
CP001043_0465 CDS_533522-534823 50.1 5.7e-14 1
CP001043_1135 CDS_1283440-1284948 47.5 3e-13 1
CP001043_0222 CDS_249625-251676 42.2 9.6e-12 1
CP001043_0994 CDS_1124887-1123538 40.6 2.8e-11 1
CP001043_0039 CDS_47612-50023 39.7 5.1e-11 1
CP001043_2335 CDS_2646623-2645022 37.6 1.9e-10 1
CP001043_1456 CDS_1656683-1659208 31.6 1e-08 1
CP001043_0065 CDS_76529-77833 31.1 1.4e-08 1
CP001043_2759 CDS_3131363-3132676 27.2 1.8e-07 1
CP001043_1181 CDS_1337120-1335765 26.8 2.2e-07 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001043_0130 1/1 233 301 .. 1 87 [] 93.1 3.5e-26
CP001043_0354 1/1 846 911 .. 1 87 [] 91.8 8.4e-26
CP001043_0880 1/1 206 272 .. 1 87 [] 87.0 1.9e-24
CP001043_2035 1/1 683 750 .. 1 87 [] 80.0 1.9e-22
CP001043_0132 1/2 362 429 .. 1 87 [] 76.2 2.2e-21
CP001043_0131 1/1 139 206 .. 1 87 [] 72.7 2.3e-20
CP001043_0433 1/1 278 343 .. 1 87 [] 66.0 1.8e-18
CP001043_3029 1/1 237 302 .. 1 87 [] 60.4 6.6e-17
CP001043_1465 1/1 152 220 .. 1 87 [] 60.0 8.8e-17
CP001043_1176 1/1 248 313 .. 1 87 [] 55.3 1.8e-15
CP001043_0637 1/1 251 321 .. 1 87 [] 51.8 1.9e-14
CP001043_0984 1/1 290 356 .. 1 87 [] 51.6 2.1e-14
CP001043_2137 1/1 223 281 .. 1 87 [] 50.3 4.9e-14
CP001043_0465 1/1 213 278 .. 1 87 [] 50.1 5.7e-14
CP001043_1135 1/1 270 338 .. 1 87 [] 47.5 3e-13
CP001043_0222 1/1 437 499 .. 1 81 [. 42.2 9.6e-12
CP001043_0994 1/1 234 293 .. 1 87 [] 40.6 2.8e-11
CP001043_0039 1/1 534 606 .. 1 87 [] 39.7 5.1e-11
CP001043_2335 1/1 155 224 .. 1 87 [] 37.6 1.9e-10
CP001043_1456 1/1 591 661 .. 1 87 [] 31.6 1e-08
CP001043_0065 1/1 201 270 .. 1 87 [] 31.1 1.4e-08
CP001043_2759 1/1 218 276 .. 1 87 [] 27.2 1.8e-07
CP001043_1181 1/1 243 301 .. 1 87 [] 26.8 2.2e-07

Alignments of top-scoring domains:
CP001043_0130: domain 1 of 1, from 233 to 301: score 93.1, E = 3.5e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+fl+n+sHELRTPL++Ir+++ lLl++ld ++ls eq
CP001043_0 233 MKSRFLSNMSHELRTPLSSIRALSNLLLNRLD------GDLSGEQ-- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i+++ae l++++ndlLdl++ieag
CP001043_0 272 ----------ERQVLLIRKSAEDLSEIVNDLLDLAKIEAG 301

CP001043_0354: domain 1 of 1, from 846 to 911: score 91.8, E = 8.4e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak++fla++sHE+RTP+++++g++e+L++ t l+++q
CP001043_0 846 AKDDFLAMMSHEIRTPMNGVLGLVEVLER---------TRLDADQ-- 881

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+l i+++a ll++++dlLd+s+ieag
CP001043_0 882 ----------GEMLGMIHESAGALLQILDDLLDYSKIEAG 911

CP001043_0880: domain 1 of 1, from 206 to 272: score 87.0, E = 1.9e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHEL+TPLt+++g++e+++e +l+e +r
CP001043_0 206 MRRDFVANVSHELKTPLTVLSGFLETMRE---------IPLDESER- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ + ++a+r++++++dlL l+ +e
CP001043_0 243 ----------VRYLDLMMQQAQRMQHIVSDLLVLATLEGD 272

CP001043_2035: domain 1 of 1, from 683 to 750: score 80.0, E = 1.9e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPLtaI g++++L + +++++++ q
CP001043_2 683 LRNSLLSAISHDLRTPLTAIVGFSSMLAA-------QRDARTDAQ-- 720

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ i++ea r+ ++ +lLd++r++ag
CP001043_2 721 ----------GELVDAIHEEALRMTGIVTNLLDMARLQAG 750

CP001043_0132: domain 1 of 2, from 362 to 429: score 76.2, E = 2.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ f++n+sHE+RTPLt ++g +e Ll+ + +++s+ +
CP001043_0 362 AKTTFFSNISHEFRTPLTLMLGPLEELLA-------RPDAASASD-- 399

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+++e+ +r + rll+L+n lLd+srieag
CP001043_0 400 ----------RQLIEVTHRNGLRLLKLVNALLDFSRIEAG 429

CP001043_0131: domain 1 of 1, from 139 to 206: score 72.7, E = 2.3e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++fla+l+HELR+PL+ Ir ++el+ ++ +++ +
CP001043_0 139 RKDQFLATLAHELRNPLAPIRNAVELMDPRY-------HAAEDAV-- 176

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++r++e+l+rL++dlLd sri +g
CP001043_0 177 ----------CHARMIARRQVEHLSRLVDDLLDVSRITHG 206

CP001043_0433: domain 1 of 1, from 278 to 343: score 66.0, E = 1.8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++H+++TPL+++r+ ael+l+ +++s+e
CP001043_0 278 LQKRFIADAAHQMKTPLAGLRTQAELALR---------QDASAEV-- 313

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ le i ++e+ rL+ +lL l+r+e+
CP001043_0 314 ----------HRSLEQIATSSEHAARLVTQLLALARAENR 343

CP001043_3029: domain 1 of 1, from 237 to 302: score 60.4, E = 6.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLtaI+++ae + +++++q+
CP001043_3 237 AQRKFIADAAHQLRTPLTAIKLHAEQAAI----------ARDPQQT- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ++ +a+r rL n+lL l+r+e g
CP001043_3 273 ----------LAAVKELRAAADRAVRLSNQLLSLARAEPG 302

CP001043_1465: domain 1 of 1, from 152 to 220: score 60.0, E = 8.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++nl+HE+++PL +Irg+a+lL+ el +e+ +++
CP001043_1 152 VNKQLIRNLAHEIKNPLGGIRGAAQLLEFEL-------GERERDEL- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey++++++e++rl+ L+++lL+ r +
CP001043_1 191 ----------REYTQVVIKESDRLQTLVDRLLEPHRHPHI 220

CP001043_1176: domain 1 of 1, from 248 to 313: score 55.3, E = 1.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HEL+TPL+aI+ a+++l+ ++ +++q
CP001043_1 248 RERAFTADAAHELKTPLAAIKVQAQVALA---------AHDGAQQ-- 283

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ + ++r +L ++lL l+r+++
CP001043_1 284 ----------QQAMQRVVQGVDRSAHLAEQLLLLARLDER 313

CP001043_0637: domain 1 of 1, from 251 to 321: score 51.8, E = 1.9e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+l+HEL++PLtaI+ + +++++++d +e s+
CP001043_0 251 TMGELAASLAHELNQPLTAILSNGQAAQRFMD------QEPSDLA-- 289

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+r++l+ i +++ r ++ i++++ + + +++
CP001043_0 290 --------EVRDILKDIVDDSGRASEVIRRMRAFVKKDEQ 321

CP001043_0984: domain 1 of 1, from 290 to 356: score 51.6, E = 2.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak++fla+lsHELRTPLt +++ a +L+ + +e +
CP001043_0 290 AKDRFLAMLSHELRTPLTPVLAGARMLEI---------MPDLPEPV- 326

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + i+r +e rLi+dlLdl+r +g
CP001043_0 327 ----------RAGVVMIRRNVELEARLIDDLLDLTRVANG 356

CP001043_2137: domain 1 of 1, from 223 to 281: score 50.3, E = 4.9e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+L+TPL+ +r+ ae+++e
CP001043_2 223 DRAVMLAGVAHDLKTPLARLRLRAEMMEE------------------ 251

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + + r+++++ ++++++L ++ +a
CP001043_2 252 ----------AKMRDGVVRDVDSMTHIVEQFLVFAHDGAD 281

CP001043_0465: domain 1 of 1, from 213 to 278: score 50.1, E = 5.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+a++ ++l + +++e +r
CP001043_0 213 TQKAFVADAAHELRTPLAAVQIQSQLVAR----------AQDEAER- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+l+ ++ + r rL ++lL l+r e
CP001043_0 249 ----------SEALRDLQAGVTRATRLAEQLLALARSEPD 278

CP001043_1135: domain 1 of 1, from 270 to 338: score 47.5, E = 3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +sH+L PL a+ g ++lL++++ + l++
CP001043_1 270 DLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQ------GQLDARA-- 308

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++ + + a r+++Li+dlL +sr +
CP001043_1 309 ----------EEFITHAVDGATRMQKLIDDLLSYSRVGRS 338

CP001043_0222: domain 1 of 1, from 437 to 499: score 42.2, E = 9.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a++ HEL++PL+a+rg+++ + +l + + e +
CP001043_0 437 ALGQMAAGITHELNQPLAALRGFSDNTRVFL-------ERGDQESA- 475

peLRledpeyreyletilreaerllrLindlLdl<-*
+e le i +er+ ++ n+l +
CP001043_0 476 ----------KENLEAIAALTERMGKITNQLKLF 499

CP001043_0994: domain 1 of 1, from 234 to 293: score 40.6, E = 2.8e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la++sH+LRTPL+ +r+ +e+ +
CP001043_0 234 DRALMLAGISHDLRTPLARLRLETEMSPSD----------------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++++e+++ +i ++Ld++r +
CP001043_0 264 ----------QATKDAMIDDIEQMDMIIGRFLDYARPVQR 293

CP001043_0039: domain 1 of 1, from 534 to 606: score 39.7, E = 5.1e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae L+++l + + + ++e +
CP001043_0 534 AWGEVARRLAHEIKNPLTPIQLSAERLQMKL---ADKLMPSDAEVL- 576

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ti +++ + ++++d++d++r
CP001043_0 577 ----------KRGATTIVNQVAAMKQMVDDFRDYARTPPA 606

CP001043_2335: domain 1 of 1, from 155 to 224: score 37.6, E = 1.9e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++ +++H++++ L ++ gy+++L++ ++++++ + +
CP001043_2 155 ALGQLTGGIAHDFNNLLQVMAGYVDVLQM------GIEGHAQSAVM- 194

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l++i+ ++ L ++lL ++r +
CP001043_2 195 ----------AQSLDRIRGAVAKATTLTQQLLAFARKQKL 224

CP001043_1456: domain 1 of 1, from 591 to 661: score 31.6, E = 1e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++l+HEL++PL+aI y++ + l +++ +++ +
CP001043_1 591 TMGEMASSLAHELNQPLAAINNYCSGTVA-----LVKSGRTTPDNL- 631

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+ ++a r +i +++++ + ++
CP001043_1 632 ----------LPVLEKTAQQAVRAGMIIKRIREFVKRSEP 661

CP001043_0065: domain 1 of 1, from 201 to 270: score 31.1, E = 1.4e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ +a+++HE+ TPL++I +++e L++ +++s+e +
CP001043_0 201 ALGVQAATVAHEIGTPLSTIAMLTEELRD---------AARSDEGLK 238

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
p+ + l++++++ + + + +l+ + +
CP001043_0 239 PY--------AADLDILDQQMTLCTSALARLRSRASTQGS 270

CP001043_2759: domain 1 of 1, from 218 to 276: score 27.2, E = 1.8e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +la+++H+L+ PLt +++ a++L +
CP001043_2 218 DQAVMLAGVAHDLKAPLTRLKLRASVLTD------------------ 246

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++r++++l ++++++L+++ a+
CP001043_2 247 ----------ENERAGLIRDVDSLTNIVQQFLEFAGQSAE 276

CP001043_1181: domain 1 of 1, from 243 to 301: score 26.8, E = 2.2e-07
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + la++sH+L TP+t +r+ a++L +e++
CP001043_1 243 ERLQILAAISHDLQTPITRMRLRADMLDDEAE--------------- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++++ ++ L+++ ++r +g
CP001043_1 275 -------------RGRLQKDLKEMELLVREGVAYARTLHG 301


Histogram of all scores:
score obs exp (one = represents 11 sequences)
----- --- ---
-14 8 0|=
-13 35 2|*===
-12 117 70|======*====
-11 278 364|========================== *
-10 488 675|============================================= *
-9 614 697|======================================================== *
-8 527 522|===============================================*
-7 417 329|=============================*========
-6 261 189|=================*======
-5 142 103|=========*===
-4 75 55|====*==
-3 34 29|==*=
-2 24 15|=*=
-1 12 8|*=
0 6 4|*
1 3 2|*
2 2 1|*
> 3 29 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 192.3040
P(chi-square) = 2.929e-35

Total sequences searched: 3072

Whole sequence top hits:
tophits_s report:
Total hits: 23
Satisfying E cutoff: 23
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 23
Satisfying E cutoff: 23
Total memory: 30K


Acknowledgements:

This research is funded by:

Developed by: