Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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3 accessions found for   

Data for CP001069  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001069.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001069_0421 CDS_482500-480464 67.2 2.9e-19 1
CP001069_0431 CDS_493003-494559 64.4 1.9e-18 1
CP001069_0048 CDS_54933-57359 62.0 8.9e-18 1
CP001069_1070 CDS_1210738-1209422 60.5 2.3e-17 1
CP001069_0017 CDS_17844-15460 60.4 2.5e-17 1
CP001069_0409 CDS_464308-465594 54.7 1e-15 1
CP001069_0895 CDS_1025837-1024341 35.5 2.9e-10 1
CP001069_0028 CDS_30651-32558 30.2 9.1e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001069_0421 1/1 298 364 .. 1 87 [] 67.2 2.9e-19
CP001069_0431 1/1 281 345 .. 1 87 [] 64.4 1.9e-18
CP001069_0048 1/1 315 380 .. 1 87 [] 62.0 8.9e-18
CP001069_1070 1/1 215 280 .. 1 87 [] 60.5 2.3e-17
CP001069_0017 1/1 415 482 .. 1 87 [] 60.4 2.5e-17
CP001069_0409 1/1 217 275 .. 1 87 [] 54.7 1e-15
CP001069_0895 1/1 244 309 .. 1 87 [] 35.5 2.9e-10
CP001069_0028 1/1 407 475 .. 1 87 [] 30.2 9.1e-09

Alignments of top-scoring domains:
CP001069_0421: domain 1 of 1, from 298 to 364: score 67.2, E = 2.9e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++fla++sHELRTPL+a++g a+lL ++++ +e
CP001069_0 298 LKDDFLATVSHELRTPLNAVLGWAQLLNMRAY----------DEA-- 332

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ +e i+r+a+ +Li+dlLd+s i +g
CP001069_0 333 --------MFKRGIEAIERSARTQVHLIDDLLDMSAILSG 364

CP001069_0431: domain 1 of 1, from 281 to 345: score 64.4, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a++sHELRTPL+++rg +e+L++++ +l++
CP001069_0 281 MRRQLTADISHELRTPLAVLRGELEALEDGV-------RPLTATS-- 318

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l +++ e+ l++Li+dl +ls ++ g
CP001069_0 319 -------------LASLQAEVSTLSKLIDDLYELSLADVG 345

CP001069_0048: domain 1 of 1, from 315 to 380: score 62.0, E = 8.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k f+a +sHE+RTP+++I+ +elL++ + l+ +q
CP001069_0 315 DKAMFVAFISHEIRTPMHTILSSLELLQR---------SQLNGQQ-- 350

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++e ll+L++d+L++sr+e+
CP001069_0 351 ----------ASRAVAAISASETLLALLDDVLEYSRLESR 380

CP001069_1070: domain 1 of 1, from 215 to 280: score 60.5, E = 2.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++H LRTPL+a+++ ++++ + ++see+r
CP001069_1 215 HQRAFVADAAHALRTPLAALKLQLQVADR----------AQSEEER- 250

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + ++r +er+ rL+ +lL+l+r e g
CP001069_1 251 ----------RAAHADLHRGVERMIRLVGQLLTLARQEPG 280

CP001069_0017: domain 1 of 1, from 415 to 482: score 60.4, E = 2.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++fla +sHELR PL++I+ + +L+++l ++ s+
CP001069_0 415 ARDQFLAVVSHELRSPLNGIQNWTYVLENQL-------SDGSPLV-- 452

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ +e+ rLi+dlLd +r +g
CP001069_0 453 ----------QRALAGIKTGVEQQVRLIEDLLDATRVMSG 482

CP001069_0409: domain 1 of 1, from 217 to 275: score 54.7, E = 1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +la+++H+L+TPL+ +r+ ae+L +
CP001069_0 217 ERNTMLAGIAHDLKTPLSRLRLRAEMLAD------------------ 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ i+r++e+++++++++L +++ +
CP001069_0 246 ----------QKAGAGIERDVESMSAIVEQFLAYAQSGDS 275

CP001069_0895: domain 1 of 1, from 244 to 309: score 35.5, E = 2.9e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+a+++HELRTPL+aI++ a + se++r
CP001069_0 244 ADRRFFADAAHELRTPLAAIQAQAYVVSH----------SDSEDDR- 279

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l+ +r + r + + lL ++r++a
CP001069_0 280 ----------STALREFDRGISRATQSLAKLLAIARLDAR 309

CP001069_0028: domain 1 of 1, from 407 to 475: score 30.2, E = 9.1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++a++ HEL++PLta+ ++++ + la+++ +e
CP001069_0 407 VLGQMAAGITHELNQPLTALTTLSDNANQ-----LAERGRIDEVR-- 446

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l i + a+r+ r+++ + +sr +
CP001069_0 447 -----------GNLTHISQLANRMGRIVSHIKAFSRKGDA 475


Histogram of all scores:
score obs exp (one = represents 4 sequences)
----- --- ---
-15 2 0|=
-14 8 0|==
-13 9 0|===
-12 40 26|======*===
-11 112 136|============================ *
-10 183 253|============================================== *
-9 215 261|====================================================== *
-8 223 196|================================================*=======
-7 151 123|==============================*=======
-6 82 71|=================*===
-5 56 39|=========*====
-4 27 20|====*==
-3 21 11|==*===
-2 7 5|=*
-1 5 3|*=
0 0 1|*
1 1 0|=
2 1 0|=
3 0 0|
> 4 10 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 69.4899
P(chi-square) = 5.562e-11

Total sequences searched: 1153

Whole sequence top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: