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Firmicutes Fusobacteria Gammaproteobacteria
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Thermotogae
Classification of phyla is from NCBI page
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Data for CP001110  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001110.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001110_1579 CDS_1817137-1818963 90.2 2.2e-25 1
CP001110_0918 CDS_1030239-1028737 55.7 1.3e-15 1
CP001110_0636 CDS_724585-728844 53.8 4.5e-15 1
CP001110_1224 CDS_1384254-1386296 50.3 4.2e-14 1
CP001110_2557 CDS_2851840-2855667 48.5 1.4e-13 1
CP001110_1838 CDS_2072100-2070148 47.3 3.1e-13 1
CP001110_1532 CDS_1749068-1752415 33.7 2.2e-09 1
CP001110_1989 CDS_2228199-2224825 32.2 5.9e-09 1
CP001110_1545 CDS_1776535-1773380 30.0 2.4e-08 1
CP001110_1115 CDS_1254857-1258237 29.5 3.4e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001110_1579 1/1 363 430 .. 1 87 [] 90.2 2.2e-25
CP001110_0918 1/1 274 340 .. 1 87 [] 55.7 1.3e-15
CP001110_0636 1/1 1024 1090 .. 1 87 [] 53.8 4.5e-15
CP001110_1224 1/1 464 533 .. 1 87 [] 50.3 4.2e-14
CP001110_2557 1/1 904 970 .. 1 87 [] 48.5 1.4e-13
CP001110_1838 1/1 286 352 .. 1 87 [] 47.3 3.1e-13
CP001110_1532 1/1 743 809 .. 1 87 [] 33.7 2.2e-09
CP001110_1989 1/1 750 816 .. 1 87 [] 32.2 5.9e-09
CP001110_1545 1/1 666 732 .. 1 87 [] 30.0 2.4e-08
CP001110_1115 1/1 751 818 .. 1 87 [] 29.5 3.4e-08

Alignments of top-scoring domains:
CP001110_1579: domain 1 of 1, from 363 to 430: score 90.2, E = 2.2e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a++sHELRTPLt+I gy+e+Ll+ +++ e++++
CP001110_1 363 IRRDFVASVSHELRTPLTVITGYTETLLD---------GAMHEPEHA 400

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l+til ++e+l +L+nd+Ldlsrie+g
CP001110_1 401 ----------TAFLQTILLATEQLTALVNDVLDLSRIESG 430

CP001110_0918: domain 1 of 1, from 274 to 340: score 55.7, E = 1.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a++sHEL+TPL+ ++g++e+L + ++ e+
CP001110_0 274 REKHFTADASHELKTPLAIVKGTLEVLIR---------KPREREH-- 309

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ ++ l+e++r+ +Li++lL l+r e+
CP001110_0 310 ---------YEARIQFCLKELNRMAKLIDQLLMLARYESS 340

CP001110_0636: domain 1 of 1, from 1024 to 1090: score 53.8, E = 4.5e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++ +++H++++ Lt I+gyae+ l +++q
CP001110_0 1024 TIGTLAGGIAHDFNNILTPIMGYAEMGLL--------TLSGDAPQ-- 1060

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y++ i ++a+r ++L++++L++sr+++
CP001110_0 1061 ----------HDYFSEIVNAADRAQNLVSQILTFSRAQES 1090

CP001110_1224: domain 1 of 1, from 464 to 533: score 50.3, E = 4.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++e++++++HE+R+PL+aI +a+ L e+ +++++ee+
CP001110_1 464 AMGELASGVAHEIRNPLNAIGILAQRLAIEF------SPTADEEE-- 502

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr++++ + +e+ r +++i+++L ++r
CP001110_1 503 ---------YRQLVRAVVSEVYRVNAIIQRFLKFARPSKL 533

CP001110_2557: domain 1 of 1, from 904 to 970: score 48.5, E = 1.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++ +++H++++ Lt I+gyae+ ++ +++ +
CP001110_2 904 TIGTLAGGIAHDFNNILTPILGYAEMGIL---------SPSNDDFQ- 940

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ey++ i+++aer +L+ ++L++s +++
CP001110_2 941 ----------QEYFSEIIKAAERAKNLVAQILTFSMAQES 970

CP001110_1838: domain 1 of 1, from 286 to 352: score 47.3, E = 3.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++++ +++H+L++ Lt I+gyae+L++el + ++ q
CP001110_1 286 SIGRLAGGVAHDLNNLLTPILGYAEMLEMEL--------AGNAGQ-- 322

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ i+r++ + ++Li +lL +sr ++
CP001110_1 323 ----------QEEVRAIQRASTSARKLIWQLLAFSRTQTL 352

CP001110_1532: domain 1 of 1, from 743 to 809: score 33.7, E = 2.2e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++++ +++H++++ Lt I+g++e++le + ++ q+
CP001110_1 743 MVGRLAGGIAHDFNNMLTLILGHTEMALE----------HFDPSQT- 778

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ le i+++a r +L ++lL ++r +
CP001110_1 779 ---------VYTDLEAIREAATRSADLTRQLLAFARKQII 809

CP001110_1989: domain 1 of 1, from 750 to 816: score 32.2, E = 5.9e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++ +++H++++ L +I+g+ae++l +++ e +
CP001110_1 750 LVGRLAGGIAHDFNNMLCVILGHAEMALL---------DNQLNESL- 786

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re l+ i ++ae +L +lL ++r +
CP001110_1 787 ----------RESLQEIFNAAEKSADLTHQLLAFARKQPL 816

CP001110_1545: domain 1 of 1, from 666 to 732: score 30.0, E = 2.4e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++++ +++H++++ Lt+I+g++e++ e +++q+
CP001110_1 666 MIGRLAGGIAHDFNNMLTVILGHSEMAIE---------LFDPSQQA- 702

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le i++++ r +L ++lL ++r +
CP001110_1 703 ----------YADLEAIRQAGARSADLTRQLLAFARKQIV 732

CP001110_1115: domain 1 of 1, from 751 to 818: score 29.5, E = 3.4e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++ +++H++++ L++I+g++e++ + +e+ e+ l
CP001110_1 751 LVGQLAGGIAHDFNNMLAVIIGNIEMAMD---------QEAAYEEPL 788

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+ il++a r +L ++lL ++r +
CP001110_1 789 ----------PFNLKNILNAATRSAHLTRQLLAFARKQPV 818


Histogram of all scores:
score obs exp (one = represents 9 sequences)
----- --- ---
-15 2 0|=
-14 8 0|=
-13 42 2|*====
-12 152 61|======*==========
-11 284 320|================================ *
-10 447 595|================================================== *
-9 531 614|==========================================================*
-8 403 460|============================================= *
-7 299 290|================================*=
-6 235 166|==================*========
-5 124 91|==========*===
-4 67 49|=====*==
-3 48 25|==*===
-2 21 13|=*=
-1 8 7|*
0 9 3|*
1 3 1|*
2 1 1|*
3 1 0|=
> 4 22 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 260.1808
P(chi-square) = 0

Total sequences searched: 2707

Whole sequence top hits:
tophits_s report:
Total hits: 10
Satisfying E cutoff: 10
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 10
Satisfying E cutoff: 10
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: