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Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

3 accessions found for Salmonella enterica subsp. enterica serovar Newport str. SL254  

Data for CP001113  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001113.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001113_2981 CDS_3090858-3093614 100.2 5.5e-28 1
CP001113_0410 CDS_455956-457251 90.2 3.7e-25 1
CP001113_1418 CDS_1479039-1476277 82.3 6.2e-23 1
CP001113_2304 CDS_2375356-2372510 81.3 1.2e-22 1
CP001113_3358 CDS_3474887-3472551 78.9 5.7e-22 1
CP001113_3847 CDS_3997083-3999770 72.8 3e-20 1
CP001113_4055 CDS_4230387-4229014 67.0 1.3e-18 1
CP001113_2174 CDS_2234547-2235950 63.5 1.4e-17 1
CP001113_4193 CDS_4378573-4379970 62.5 2.5e-17 1
CP001113_0714 CDS_774309-771625 61.1 6.6e-17 1
CP001113_4000 CDS_4179910-4178861 60.3 1.1e-16 1
CP001113_4603 CDS_4815131-4816555 59.8 1.5e-16 1
CP001113_1122 CDS_1185980-1184616 57.5 6.8e-16 1
CP001113_3215 CDS_3330784-3332133 56.8 1.1e-15 1
CP001113_3524 CDS_3640885-3639542 54.9 3.7e-15 1
CP001113_4313 CDS_4524819-4523740 47.7 4.1e-13 1
CP001113_1490 CDS_1547149-1545848 47.4 4.8e-13 1
CP001113_2797 CDS_2910414-2908999 36.6 5.6e-10 1
CP001113_2432 CDS_2509474-2507468 35.3 1.3e-09 1
CP001113_1412 CDS_1470794-1472542 31.5 1.6e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001113_2981 1/1 292 357 .. 1 87 [] 100.2 5.5e-28
CP001113_0410 1/1 203 269 .. 1 87 [] 90.2 3.7e-25
CP001113_1418 1/1 395 460 .. 1 87 [] 82.3 6.2e-23
CP001113_2304 1/1 469 534 .. 1 87 [] 81.3 1.2e-22
CP001113_3358 1/1 282 347 .. 1 87 [] 78.9 5.7e-22
CP001113_3847 1/1 428 493 .. 1 87 [] 72.8 3e-20
CP001113_4055 1/1 238 300 .. 1 87 [] 67.0 1.3e-18
CP001113_2174 1/1 240 304 .. 1 87 [] 63.5 1.4e-17
CP001113_4193 1/1 246 312 .. 1 87 [] 62.5 2.5e-17
CP001113_0714 1/1 663 730 .. 1 87 [] 61.1 6.6e-17
CP001113_4000 1/1 129 186 .. 1 79 [. 60.3 1.1e-16
CP001113_4603 1/1 255 320 .. 1 87 [] 59.8 1.5e-16
CP001113_1122 1/1 236 302 .. 1 87 [] 57.5 6.8e-16
CP001113_3215 1/1 236 302 .. 1 87 [] 56.8 1.1e-15
CP001113_3524 1/1 230 290 .. 1 87 [] 54.9 3.7e-15
CP001113_4313 1/1 145 205 .. 1 87 [] 47.7 4.1e-13
CP001113_1490 1/1 211 271 .. 1 87 [] 47.4 4.8e-13
CP001113_2797 1/1 246 311 .. 1 87 [] 36.6 5.6e-10
CP001113_2432 1/1 447 515 .. 1 87 [] 35.3 1.3e-09
CP001113_1412 1/1 347 416 .. 1 87 [] 31.5 1.6e-08

Alignments of top-scoring domains:
CP001113_2981: domain 1 of 1, from 292 to 357: score 100.2, E = 5.5e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CP001113_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELNPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP001113_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CP001113_0410: domain 1 of 1, from 203 to 269: score 90.2, E = 3.7e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e+++e ++l +r
CP001113_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMQE---------QALEGATR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t+++++ r++ L+ +lL+ls+iea
CP001113_0 240 ----------EKALHTMREQTYRMEGLVKQLLTLSKIEAA 269

CP001113_1418: domain 1 of 1, from 395 to 460: score 82.3, E = 6.2e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks l +sHELRTP+++++g++elL++ t+l+ eq
CP001113_1 395 RKSIHLTVISHELRTPMNGVLGAIELLQT---------TPLNIEQ-- 430

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +t+++++ +ll++in+lLd+srie+g
CP001113_1 431 ----------QGLADTARNCTLSLLAIINNLLDFSRIESG 460

CP001113_2304: domain 1 of 1, from 469 to 534: score 81.3, E = 1.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001113_2 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ + +++ ll++i+d+Ld+s+ie++
CP001113_2 505 ----------ERLVTAMNNSSSLLLKIISDILDFSKIESE 534

CP001113_3358: domain 1 of 1, from 282 to 347: score 78.9, E = 5.7e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ t+l++eq
CP001113_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TDLTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001113_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001113_3847: domain 1 of 1, from 428 to 493: score 72.8, E = 3e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+++lL + +l +
CP001113_3 428 AKSTFLAAMSHEIRTPLYGILGTVQLLAD---------KPLMANY-- 463

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll+++nd+Ld+s ie g
CP001113_3 464 ----------RDDLQAINDSGESLLAILNDILDYSAIEVG 493

CP001113_4055: domain 1 of 1, from 238 to 300: score 67.0, E = 1.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP001113_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RGGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP001113_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP001113_2174: domain 1 of 1, from 240 to 304: score 63.5, E = 1.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ ++e
CP001113_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RQFTPES-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP001113_2 278 -------------VTSLQAEVGTLTKLVDDLHQLSLSDEG 304

CP001113_4193: domain 1 of 1, from 246 to 312: score 62.5, E = 2.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +t+++ e
CP001113_4 246 AMGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RTPAGGES-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ +++ +ea+rl+r +++lL+l + +
CP001113_4 283 ----------HELAQVMAKEADRLNRVVSELLELVKPAHL 312

CP001113_0714: domain 1 of 1, from 663 to 730: score 61.1, E = 6.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + +++++
CP001113_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASAGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CP001113_0 701 ----------ARQASEIRQHILNTTRLVNNLLDMARIQSG 730

CP001113_4000: domain 1 of 1, from 129 to 186: score 60.3, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001113_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP001113_4 165 ----------TEYTKVIIEQADRLRNLVDRLL 186

CP001113_4603: domain 1 of 1, from 255 to 320: score 59.8, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++ + +l HEL+ PL+aIrg+ae+L+e ++ +
CP001113_4 255 EIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPADVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++e il + r+++L++ lL +r+e+
CP001113_4 291 ----------TRFTENILAQNTRMQALVETLLRQARLENR 320

CP001113_1122: domain 1 of 1, from 236 to 302: score 57.5, E = 6.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +l+HELRTP++ ++g +++l +e+s+e+
CP001113_1 236 RLNQFADDLAHELRTPVNILLGKNQVMLS---------QERSAEE-- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+++l ++e+e l+rL +++L l+r+e++
CP001113_1 272 ---------YQQALVDNIEELEGLSRLTENILFLARAEHQ 302

CP001113_3215: domain 1 of 1, from 236 to 302: score 56.8, E = 1.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PL+a++ +e+++ + ++ r
CP001113_3 236 RERRFTSDAAHELRSPLAALKVQTEVAQL---------SGDDPLSR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l ++ ++r rL+++lL+lsr+++
CP001113_3 273 ----------DKALAQLHAGIDRATRLVDQLLTLSRLDSL 302

CP001113_3524: domain 1 of 1, from 230 to 290: score 54.9, E = 3.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e e+
CP001113_3 230 DRTLLMAGVSHDLRTPLTRIRLATEMMGE--------------ED-- 260

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001113_3 261 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 290

CP001113_4313: domain 1 of 1, from 145 to 205: score 47.7, E = 4.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CP001113_4 145 NERLFTADVAHELRTPLSGVRLHLELLSK---------TH------- 175

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ++++ + +++lL+l+r ++
CP001113_4 176 ----------NVDVAPLIARLDQMMDSVSQLLQLARVGQS 205

CP001113_1490: domain 1 of 1, from 211 to 271: score 47.4, E = 4.8e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ ++ l++++
CP001113_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSEN-----------LTPPE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001113_1 245 -------------SQALNRDIGQLEALIEELLTYARLDRP 271

CP001113_2797: domain 1 of 1, from 246 to 311: score 36.6, E = 5.6e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f a++sH+L+TPL+++++ a ++l+ + + +
CP001113_2 246 RQERFSADASHQLKTPLAVLKTQAAVALA----------SQHPHH-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e l+ + +++ +L ++lL+ls +
CP001113_2 281 ---------WYESLQAMSVTLDSTIQLTERLLQLSAVKHK 311

CP001113_2432: domain 1 of 1, from 447 to 515: score 35.3, E = 1.3e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l+HE+++PL+a+++y+ ++ + a+++ +s +
CP001113_2 447 VVGQTMTTLAHEINQPLNALSMYLFTAGR------AIEQGQSGQA-- 485

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l +++ ++r++++i+ l++++r +
CP001113_2 486 ----------RNTLTKAEGLINRIDAIIRSLRQFTRRAEL 515

CP001113_1412: domain 1 of 1, from 347 to 416: score 31.5, E = 1.6e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++ +HEL++PL+aIr ya+ +l +l +++e++ l
CP001113_1 347 VLGEMTSGFAHELNQPLSAIRHYAQGCLIRL-------RAADEQHPL 386

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+le i+++a+r + +++l+ +g
CP001113_1 387 ----------LPALEQIDQQAQRGADTLRNLRHWVSQAQG 416


Histogram of all scores:
score obs exp (one = represents 15 sequences)
----- --- ---
-15 10 0|=
-14 53 0|====
-13 136 3|*=========
-12 277 105|======*============
-11 527 546|====================================*
-10 744 1014|================================================== *
-9 840 1047|======================================================== *
-8 751 784|=================================================== *
-7 504 494|================================*=
-6 310 284|==================*==
-5 223 156|==========*====
-4 93 83|=====*=
-3 41 44|==*
-2 29 23|=*
-1 24 12|*=
0 14 6|*
1 7 3|*
2 5 1|*
3 2 0|=
4 0 0|
> 5 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 449.5828
P(chi-square) = 0

Total sequences searched: 4612

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: