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Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
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Firmicutes Fusobacteria Gammaproteobacteria
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Thermotogae
Classification of phyla is from NCBI page
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25 projects found  

1 accessions found for Acidithiobacillus ferrooxidans ATCC 53993  

Data for CP001132  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001132.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001132_1128 CDS_1122864-1124192 74.8 5.3e-21 1
CP001132_2502 CDS_2542368-2540821 71.3 5.1e-20 1
CP001132_1843 CDS_1871081-1868340 67.4 6.4e-19 1
CP001132_0355 CDS_340814-342406 61.6 2.8e-17 1
CP001132_2452 CDS_2481535-2480450 53.9 4.4e-15 1
CP001132_1655 CDS_1662303-1660996 47.8 2.3e-13 1
CP001132_2795 CDS_2856508-2857770 45.9 8.1e-13 1
CP001132_0024 CDS_25961-28171 44.5 2e-12 1
CP001132_0028 CDS_30028-31521 38.2 1.2e-10 1
CP001132_0602 CDS_568955-567471 35.0 1e-09 1
CP001132_1912 CDS_1951246-1949951 33.3 2.9e-09 1
CP001132_0106 CDS_101051-99750 33.3 3e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001132_1128 1/1 206 273 .. 1 87 [] 74.8 5.3e-21
CP001132_2502 1/1 259 327 .. 1 87 [] 71.3 5.1e-20
CP001132_1843 1/1 682 749 .. 1 87 [] 67.4 6.4e-19
CP001132_0355 1/1 306 371 .. 1 87 [] 61.6 2.8e-17
CP001132_2452 1/1 136 192 .. 1 78 [. 53.9 4.4e-15
CP001132_1655 1/1 218 283 .. 1 87 [] 47.8 2.3e-13
CP001132_2795 1/1 219 278 .. 1 87 [] 45.9 8.1e-13
CP001132_0024 1/1 509 580 .. 1 87 [] 44.5 2e-12
CP001132_0028 1/1 281 342 .. 1 83 [. 38.2 1.2e-10
CP001132_0602 1/1 265 333 .. 1 87 [] 35.0 1e-09
CP001132_1912 1/1 226 287 .. 1 87 [] 33.3 2.9e-09
CP001132_0106 1/1 214 274 .. 1 87 [] 33.3 3e-09

Alignments of top-scoring domains:
CP001132_1128: domain 1 of 1, from 206 to 273: score 74.8, E = 5.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHELR PLt++rg++e +l+ ++ + ++++
CP001132_1 206 VRQDFVANVSHELRSPLTVVRGFLENMLD--------SPIAADDEV- 243

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+ +++++ r+++L++dlL l+r+ea
CP001132_1 244 ----------SSQLRLMEQQTLRMQSLVEDLLSLARMEAA 273

CP001132_2502: domain 1 of 1, from 259 to 327: score 71.3, E = 5.1e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak fl+ lsHEL+TPLtaIr aelL+e+l +el++eq
CP001132_2 259 AKLHFLRQLSHELKTPLTAIREGAELLQEDLG------HELGAEQ-- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+++++++ + rl+rLi+dlL +s +e +
CP001132_2 298 ----------QEIVHIVRDNSLRLQRLIEDLLRFSLAEGP 327

CP001132_1843: domain 1 of 1, from 682 to 749: score 67.4, E = 6.4e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l ++sH+LRTPL++++g+a +L++++ + l++e+
CP001132_1 682 LQNALLGAVSHDLRTPLAGVLGTATTLQRNA-------QGLTAEE-- 719

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++le i+++++ +++ ++++L ++ +++g
CP001132_1 720 ----------HDLLENIREQTQKMEHTVDRILHMAALQSG 749

CP001132_0355: domain 1 of 1, from 306 to 371: score 61.6, E = 2.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++an++HE+R+PL++Ir + lL e ++
CP001132_0 306 ALGRLAANIAHEIRNPLSVIRHAGNLLAE---------RMDDPAS-- 341

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l++++re+ r++++++ +L+++r
CP001132_0 342 ----------QHLLDILERETVRINAIVESVLEMARPSPA 371

CP001132_2452: domain 1 of 1, from 136 to 192: score 53.9, E = 4.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e+l++l+HE+++PL ++rg+a+lL + el +++
CP001132_2 136 AAQEMLRGLAHEIKNPLGGLRGAAQLLDR----------ELQRPEL- 171

peLRledpeyreyletilreaerllrLindl<-*
++y+++il+e++rl +L+++l
CP001132_2 172 ----------KDYTRVILHEVDRLHHLVDRL 192

CP001132_1655: domain 1 of 1, from 218 to 283: score 47.8, E = 2.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a+++HELRTPLta+++ ++ L++ ++ +e
CP001132_1 218 QERRFIADAAHELRTPLTALSLQVQNLER---------ADSLSEC-- 253

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l +++ +er ++L+++lL l+r ++
CP001132_1 254 ----------QKRLLPLQSGLERSRHLLDQLLGLARQQTA 283

CP001132_2795: domain 1 of 1, from 219 to 278: score 45.9, E = 8.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ l ++sH+LRTPLt +r+ ae L +e
CP001132_2 219 EREMVLVGVSHDLRTPLTRMRLSAEFLPAE----------------- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ + i+ ++ +++ i ++Ld++r +++
CP001132_2 249 ----------EEARSEIIANIQEMDKVIHQFLDYARSGEQ 278

CP001132_0024: domain 1 of 1, from 509 to 580: score 44.5, E = 2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a se ++ l+HE+++PLt I++ ae L++++ +++ e++
CP001132_0 509 AWSEVARRLAHEIKNPLTPIQLSAERLRRKY----LERLGDEGETL- 550

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ti+++++ l +++ + +++r +
CP001132_0 551 ----------DRATRTIIHQVDALKVMVDAFSEYARQPQL 580

CP001132_0028: domain 1 of 1, from 281 to 342: score 38.2, E = 1.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+e+ a ++HE+R+ L+++rg+a L + e++
CP001132_0 281 TIGEMSAQVAHEIRNALSSLRGAARYLVR---------YEQPVNR-- 316

peLRledpeyreyletilreaerllrLindlLdlsr<-*
+e++++i++e++rl ++ + +Ld+ r
CP001132_0 317 ----------QEFINIIEEEVQRLYDMTQGFLDFGR 342

CP001132_0602: domain 1 of 1, from 265 to 333: score 35.0, E = 1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ efl+ +sHEL TPL++ r +elLl + ++l + q
CP001132_0 265 LRHEFLSQVSHELITPLASARSGSELLLS------ERIGPLLPRQ-- 303

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re le+i r+++ l + i+++Ld+ ++a
CP001132_0 304 ----------REVLEIIVRQVKELYAAIQEMLDMHALQAR 333

CP001132_1912: domain 1 of 1, from 226 to 287: score 33.3, E = 2.9e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s +l ++sH+LR PL+ +r++ elL +
CP001132_1 226 HQSLLLTGISHDLRSPLARLRMAWELLPD-------------NTP-- 257

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + e +l+++er+++L+ + L l r +
CP001132_1 258 ----------QHLREGMLQDIERMDALLAQSLALGRGMSA 287

CP001132_0106: domain 1 of 1, from 214 to 274: score 33.3, E = 3e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +l ++sHELRTPL+ ++++++l ++ ++l + +
CP001132_0 214 ERTLLLTGISHELRTPLSRLLLTLHL-QD---------PDLLAGK-- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l ++ +++ i+ +L+l r + +
CP001132_0 249 --------------AAMLVDVSEMDETIDKFLTLVRSGDE 274


Histogram of all scores:
score obs exp (one = represents 10 sequences)
----- --- ---
-14 11 0|==
-13 46 2|*====
-12 142 64|======*========
-11 283 334|============================= *
-10 479 621|================================================ *
-9 545 641|======================================================= *
-8 466 480|===============================================*
-7 327 302|==============================*==
-6 216 174|=================*====
-5 149 95|=========*=====
-4 63 51|=====*=
-3 32 27|==*=
-2 20 14|=*
-1 14 7|*=
0 9 3|*
1 6 2|*
2 2 1|*
3 2 0|=
> 4 14 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 202.1713
P(chi-square) = 2.636e-37

Total sequences searched: 2826

Whole sequence top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: