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Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

2 accessions found for Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  

Data for CP001144  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001144.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001144_2977 CDS_3154269-3157025 100.2 5.4e-28 1
CP001144_0397 CDS_454878-456173 90.2 3.7e-25 1
CP001144_1782 CDS_1878389-1881151 82.3 6.1e-23 1
CP001144_2385 CDS_2494646-2491899 80.6 1.9e-22 1
CP001144_3344 CDS_3533663-3531327 78.9 5.6e-22 1
CP001144_3821 CDS_4059546-4062233 72.8 2.9e-20 1
CP001144_4030 CDS_4296701-4295328 67.0 1.3e-18 1
CP001144_2262 CDS_2354760-2356163 63.5 1.3e-17 1
CP001144_4134 CDS_4418872-4420269 62.5 2.5e-17 1
CP001144_0730 CDS_807317-804633 61.1 6.5e-17 1
CP001144_3972 CDS_4242275-4241226 60.3 1.1e-16 1
CP001144_1071 CDS_1162141-1160777 57.5 6.7e-16 1
CP001144_4505 CDS_4830409-4831833 56.9 9.9e-16 1
CP001144_3201 CDS_3388506-3389855 55.9 1.9e-15 1
CP001144_3505 CDS_3699544-3698201 54.9 3.6e-15 1
CP001144_4228 CDS_4548466-4547387 47.7 4e-13 1
CP001144_1711 CDS_1810414-1811715 47.4 4.7e-13 1
CP001144_2802 CDS_2978468-2977053 36.6 5.5e-10 1
CP001144_2515 CDS_2636645-2634639 35.3 1.3e-09 1
CP001144_1787 CDS_1886632-1884884 31.5 1.5e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001144_2977 1/1 292 357 .. 1 87 [] 100.2 5.4e-28
CP001144_0397 1/1 203 269 .. 1 87 [] 90.2 3.7e-25
CP001144_1782 1/1 395 460 .. 1 87 [] 82.3 6.1e-23
CP001144_2385 1/1 436 501 .. 1 87 [] 80.6 1.9e-22
CP001144_3344 1/1 282 347 .. 1 87 [] 78.9 5.6e-22
CP001144_3821 1/1 428 493 .. 1 87 [] 72.8 2.9e-20
CP001144_4030 1/1 238 300 .. 1 87 [] 67.0 1.3e-18
CP001144_2262 1/1 240 304 .. 1 87 [] 63.5 1.3e-17
CP001144_4134 1/1 246 312 .. 1 87 [] 62.5 2.5e-17
CP001144_0730 1/1 663 730 .. 1 87 [] 61.1 6.5e-17
CP001144_3972 1/1 129 186 .. 1 79 [. 60.3 1.1e-16
CP001144_1071 1/1 236 302 .. 1 87 [] 57.5 6.7e-16
CP001144_4505 1/1 255 320 .. 1 87 [] 56.9 9.9e-16
CP001144_3201 1/1 236 302 .. 1 87 [] 55.9 1.9e-15
CP001144_3505 1/1 230 290 .. 1 87 [] 54.9 3.6e-15
CP001144_4228 1/1 145 205 .. 1 87 [] 47.7 4e-13
CP001144_1711 1/1 211 271 .. 1 87 [] 47.4 4.7e-13
CP001144_2802 1/1 246 311 .. 1 87 [] 36.6 5.5e-10
CP001144_2515 1/1 447 515 .. 1 87 [] 35.3 1.3e-09
CP001144_1787 1/1 347 416 .. 1 87 [] 31.5 1.5e-08

Alignments of top-scoring domains:
CP001144_2977: domain 1 of 1, from 292 to 357: score 100.2, E = 5.4e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CP001144_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELNPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP001144_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CP001144_0397: domain 1 of 1, from 203 to 269: score 90.2, E = 3.7e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e+++e ++l +r
CP001144_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMQE---------QALEGATR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t+++++ r++ L+ +lL+ls+iea
CP001144_0 240 ----------EKALHTMREQTYRMEGLVKQLLTLSKIEAA 269

CP001144_1782: domain 1 of 1, from 395 to 460: score 82.3, E = 6.1e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks l +sHELRTP+++++g++elL++ t+l+ eq
CP001144_1 395 RKSIHLTVISHELRTPMNGVLGAIELLQT---------TPLNIEQ-- 430

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +t+++++ +ll++in+lLd+srie+g
CP001144_1 431 ----------QGLADTARNCTLSLLAIINNLLDFSRIESG 460

CP001144_2385: domain 1 of 1, from 436 to 501: score 80.6, E = 1.9e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001144_2 436 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 471

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001144_2 472 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 501

CP001144_3344: domain 1 of 1, from 282 to 347: score 78.9, E = 5.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ t+l++eq
CP001144_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TDLTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001144_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001144_3821: domain 1 of 1, from 428 to 493: score 72.8, E = 2.9e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+++lL + +l +
CP001144_3 428 AKSTFLAAMSHEIRTPLYGILGTVQLLAD---------KPLMANY-- 463

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll+++nd+Ld+s ie g
CP001144_3 464 ----------RDDLQAINDSGESLLAILNDILDYSAIEVG 493

CP001144_4030: domain 1 of 1, from 238 to 300: score 67.0, E = 1.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP001144_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RGGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP001144_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP001144_2262: domain 1 of 1, from 240 to 304: score 63.5, E = 1.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ ++e
CP001144_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RQFTPES-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP001144_2 278 -------------VTSLQAEVGTLTKLVDDLHQLSLSDEG 304

CP001144_4134: domain 1 of 1, from 246 to 312: score 62.5, E = 2.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +t+++ e
CP001144_4 246 AMGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RTPAGGES-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ +++ +ea+rl+r +++lL+l + +
CP001144_4 283 ----------HELAQVMAKEADRLNRVVSELLELVKPAHL 312

CP001144_0730: domain 1 of 1, from 663 to 730: score 61.1, E = 6.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + +++++
CP001144_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASAGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CP001144_0 701 ----------ARQASEIRQHILNTTRLVNNLLDMARIQSG 730

CP001144_3972: domain 1 of 1, from 129 to 186: score 60.3, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001144_3 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP001144_3 165 ----------TEYTKVIIEQADRLRNLVDRLL 186

CP001144_1071: domain 1 of 1, from 236 to 302: score 57.5, E = 6.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +l+HELRTP++ ++g +++l +e+s+e+
CP001144_1 236 RLNQFADDLAHELRTPVNILLGKNQVMLS---------QERSAEE-- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+++l ++e+e l+rL +++L l+r+e++
CP001144_1 272 ---------YQQALVDNIEELEGLSRLTENILFLARAEHQ 302

CP001144_4505: domain 1 of 1, from 255 to 320: score 56.9, E = 9.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +
CP001144_4 255 DIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPADVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++e il + r+++L+ lL +r+e+
CP001144_4 291 ----------TRFTENILAQNTRMQALVATLLRQARLENR 320

CP001144_3201: domain 1 of 1, from 236 to 302: score 55.9, E = 1.9e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PL+a++ +e+++ + ++ r
CP001144_3 236 RERRFTSDAAHELRSPLAALKVQTEVAQL---------SGDDPLSR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l ++ ++r rL+++lL+lsr+++
CP001144_3 273 ----------DKALTQLHAGIDRATRLVDQLLTLSRLDSL 302

CP001144_3505: domain 1 of 1, from 230 to 290: score 54.9, E = 3.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e e+
CP001144_3 230 DRTLLMAGVSHDLRTPLTRIRLATEMMGE--------------ED-- 260

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001144_3 261 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 290

CP001144_4228: domain 1 of 1, from 145 to 205: score 47.7, E = 4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CP001144_4 145 NERLFTADVAHELRTPLSGVRLHLELLSK---------TH------- 175

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ++++ + +++lL+l+r ++
CP001144_4 176 ----------NVDVAPLIARLDQMMDSVSQLLQLARVGQS 205

CP001144_1711: domain 1 of 1, from 211 to 271: score 47.4, E = 4.7e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ ++ l++++
CP001144_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSEN-----------LTPPE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001144_1 245 -------------SQALNRDIGQLEALIEELLTYARLDRP 271

CP001144_2802: domain 1 of 1, from 246 to 311: score 36.6, E = 5.5e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f a++sH+L+TPL+++++ a ++l+ + + +
CP001144_2 246 RQERFSADASHQLKTPLAVLKTQAAVALA----------SQHPHH-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e l+ + +++ +L ++lL+ls +
CP001144_2 281 ---------WYESLQAMSVTLDSTIQLTERLLQLSAVKHK 311

CP001144_2515: domain 1 of 1, from 447 to 515: score 35.3, E = 1.3e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l+HE+++PL+a+++y+ ++ + a+++ +s +
CP001144_2 447 VVGQTMTTLAHEINQPLNALSMYLFTAGR------AIEQGQSGQA-- 485

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l +++ ++r++++i+ l++++r +
CP001144_2 486 ----------RNTLTKAEGLINRIDAIIRSLRQFTRRAEL 515

CP001144_1787: domain 1 of 1, from 347 to 416: score 31.5, E = 1.5e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++ +HEL++PL+aIr ya+ +l +l +++e++ l
CP001144_1 347 VLGEMTSGFAHELNQPLSAIRHYAQGCLIRL-------RAADEQHPL 386

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+le i+++a+r + +++l+ +g
CP001144_1 387 ----------LPALEQIDQQAQRGADTLRNLRHWVSQAQG 416


Histogram of all scores:
score obs exp (one = represents 15 sequences)
----- --- ---
-16 1 0|=
-15 7 0|=
-14 54 0|====
-13 120 3|*=======
-12 282 103|======*============
-11 489 535|================================= *
-10 744 992|================================================== *
-9 844 1025|========================================================= *
-8 716 767|================================================ *
-7 513 483|================================*==
-6 310 278|==================*==
-5 206 152|==========*===
-4 88 81|=====*
-3 39 43|==*
-2 29 22|=*
-1 22 11|*=
0 15 6|*
1 6 3|*
2 6 1|*
> 3 23 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 459.6311
P(chi-square) = 0

Total sequences searched: 4514

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: