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Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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2 accessions found for   

Data for CP001182  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001182.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001182_3701 CDS_3949821-3951179 72.2 3.7e-20 1
CP001182_2403 CDS_2565750-2563096 68.5 4.1e-19 1
CP001182_2570 CDS_2733298-2731940 62.1 2.8e-17 1
CP001182_0779 CDS_852941-854533 61.6 3.7e-17 1
CP001182_0318 CDS_344566-343043 59.9 1.1e-16 1
CP001182_0648 CDS_703245-701869 59.1 1.9e-16 1
CP001182_2479 CDS_2645854-2644451 58.8 2.3e-16 1
CP001182_3279 CDS_3494723-3493167 56.7 9.2e-16 1
CP001182_2259 CDS_2406900-2408009 56.2 1.3e-15 1
CP001182_3624 CDS_3863967-3867464 53.0 1.1e-14 1
CP001182_3076 CDS_3298384-3297050 50.5 5.2e-14 1
CP001182_2472 CDS_2637537-2636209 50.4 5.7e-14 1
CP001182_3559 CDS_3797422-3798879 47.0 5.2e-13 1
CP001182_3302 CDS_3521626-3520358 41.8 1.6e-11 1
CP001182_2025 CDS_2164473-2165558 41.6 1.8e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001182_3701 1/1 224 290 .. 1 87 [] 72.2 3.7e-20
CP001182_2403 1/1 656 724 .. 1 87 [] 68.5 4.1e-19
CP001182_2570 1/1 224 290 .. 1 87 [] 62.1 2.8e-17
CP001182_0779 1/1 295 360 .. 1 87 [] 61.6 3.7e-17
CP001182_0318 1/1 298 362 .. 1 87 [] 59.9 1.1e-16
CP001182_0648 1/1 240 306 .. 1 87 [] 59.1 1.9e-16
CP001182_2479 1/1 236 302 .. 1 87 [] 58.8 2.3e-16
CP001182_3279 1/1 298 362 .. 1 87 [] 56.7 9.2e-16
CP001182_2259 1/1 137 194 .. 1 79 [. 56.2 1.3e-15
CP001182_3624 1/1 804 869 .. 1 87 [] 53.0 1.1e-14
CP001182_3076 1/1 218 280 .. 1 87 [] 50.5 5.2e-14
CP001182_2472 1/1 222 284 .. 1 87 [] 50.4 5.7e-14
CP001182_3559 1/1 260 318 .. 1 87 [] 47.0 5.2e-13
CP001182_3302 1/1 177 245 .. 1 87 [] 41.8 1.6e-11
CP001182_2025 1/1 139 203 .. 1 87 [] 41.6 1.8e-11

Alignments of top-scoring domains:
CP001182_3701: domain 1 of 1, from 224 to 290: score 72.2, E = 3.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +f+ n+sHELRTPLt+++gy+e+ + ++ ++
CP001182_3 224 MRKDFVDNISHELRTPLTVLSGYIETFTD--------QEDINPRW-- 260

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ ++++++r+++L+ndlL ls +e++
CP001182_3 261 ----------KRAFDQMQSQTKRMNALVNDLLLLSNLENN 290

CP001182_2403: domain 1 of 1, from 656 to 724: score 68.5, E = 4.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s +l+++sH+LR PL++I+g+a++L + +e++e+++
CP001182_2 656 LRSALLSSVSHDLRSPLASIIGAADTLAN-------FKAEMTEQDQ- 694

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++leti+ e+erl+r i++lLd++r++++
CP001182_2 695 ----------QDLLETIHLEGERLDRYIQNLLDMTRLGHE 724

CP001182_2570: domain 1 of 1, from 224 to 290: score 62.1, E = 2.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+a++sHELR PL+aI++ +++L++++ ++ +e +
CP001182_2 224 AEQRFTADASHELRSPLSAIQMRLQVLQRKY-------QHIPELD-- 261

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+i++++ r +++++lL l+r+e +
CP001182_2 262 -----------HDFERIQEDVSRSTKILENLLLLARLEPN 290

CP001182_0779: domain 1 of 1, from 295 to 360: score 61.6, E = 3.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++e+++++sHELRTP++ Ir+ +e+L e e + +r
CP001182_0 295 AQRELMRAVSHELRTPVARIRFGTEMLAE----------EDDYNHR- 330

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ i++++e l+ Li+++++++++e+g
CP001182_0 331 ----------MHQVDMIDKDIEALNTLIDEIMTYAKLEQG 360

CP001182_0318: domain 1 of 1, from 298 to 362: score 59.9, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++ a+++HE+R+PL+aI + elL++ +e+q
CP001182_0 298 ALGQLSASIAHEIRNPLAAIVQANELLKD----------SDPEQQ-- 332

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++i ++++r++++++d L l+r e
CP001182_0 333 ----------NTLRHIIGKQTKRIDSIVQDTLGLARSERT 362

CP001182_0648: domain 1 of 1, from 240 to 306: score 59.1, E = 1.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s+f ++l+HE+RTP++ +++ ++++l ++ +
CP001182_0 240 KLSDFSSDLAHEIRTPINNLMTQTQVCLS---------RSRDINT-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+e l + l+e erl r+++d+L l+++e+g
CP001182_0 276 ---------YQEVLFSNLEEFERLARMVSDMLFLAKAEHG 306

CP001182_2479: domain 1 of 1, from 236 to 302: score 58.8, E = 2.3e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f +++HE+RTPL+ ++g +e++l+ +e+s eq
CP001182_2 236 QLNRFSEDIAHEFRTPLNNLIGQTEIALT---------GERSVEQ-- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+++l + l++ +rl r+i+ +L l+r+++
CP001182_2 272 ---------YEDLLVSHLDDYHRLKRMIDSMLFLARADQK 302

CP001182_3279: domain 1 of 1, from 298 to 362: score 56.7, E = 9.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a+ sHEL+TPL+++++ +e+++++ ++++e+
CP001182_3 298 SRRQWVADTSHELKTPLAVLQAQIEAMQDGI-------RKATPEH-- 335

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+ + r++ +l +L +dl dl++++a+
CP001182_3 336 -------------LDAMMRQVSSLKKLTQDLADLAQADAQ 362

CP001182_2259: domain 1 of 1, from 137 to 194: score 56.2, E = 1.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++++HE+++PL++Irg+++lL + l++e
CP001182_2 137 VARQLVRGVAHEIKNPLAGIRGATQLLAR----------SLNDES-- 171

peLRledpeyreyletilreaerllrLindlL<-*
y+e++++i++e++rl +L + +L
CP001182_2 172 ---------YAEFTDIIINEVDRLTNLADTML 194

CP001182_3624: domain 1 of 1, from 804 to 869: score 53.0, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+f+a++sH+L +P++a r+++ +L+ + +ee+
CP001182_3 804 SKSRFIAAASHDLLQPMHAARLFSTVLEQ---------SISTEED-- 839

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ ++r++ +++++ lLd++r+e g
CP001182_3 840 ----------RQTLQQLDRALYGAESMLSALLDIARLEGG 869

CP001182_3076: domain 1 of 1, from 218 to 280: score 50.5, E = 5.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +f+a+++HELRTP+ta+ + +++Ll ++ +e+
CP001182_3 218 EQKQFIADAAHELRTPVTALNLQTKILLSQF-----------PEH-- 251

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e l+ + + + r+++L+ +lL l++ +
CP001182_3 252 -----------ESLQNLSKGLARIQHLVTQLLALAKQDVT 280

CP001182_2472: domain 1 of 1, from 222 to 284: score 50.4, E = 5.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +ef+ ++sHELRTPLt ++g+++l+++++ ++
CP001182_2 222 REREFTGDVSHELRTPLTILKGNVQLCQAKF-------GD------- 254

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l ++++ +e ++ L++ lL ++r
CP001182_2 255 ----------DKSLVRLHNTIEDMQLLVDTLLAIARNTVK 284

CP001182_3559: domain 1 of 1, from 260 to 318: score 47.0, E = 5.2e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +la++sH+LRTPLt Ir++ae+L +
CP001182_3 260 ERRIMLAGISHDLRTPLTRIRLTAEMLPD------------------ 288

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + e + +++ +++++n++ + r ++
CP001182_3 289 ----------EFLREGLVYDVDDMDAILNQFISYMRDGSD 318

CP001182_3302: domain 1 of 1, from 177 to 245: score 41.8, E = 1.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++f++ +sH+LR P ++++g++e+L + ++++l+e +
CP001182_3 177 SKTKFFSIISHDLRAPFHGLLGFSEVLAK-------ERETLDESSI- 215

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + +++ +++ +L++ lL+ + +e g
CP001182_3 216 ----------QNIADYLYDTSQSTYNLLESLLTWAMAEGG 245

CP001182_2025: domain 1 of 1, from 139 to 203: score 41.6, E = 1.8e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + a+++HELRTP+t ++g ++ + ++++ ++
CP001182_2 139 NAQVWNAAIAHELRTPITILQGRLQGIIDGVF----------KPD-- 173

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++l+++e l++L++dl++ls e++
CP001182_2 174 ----------EVLFKSLLNQVEGLSHLVEDLRTLSLVENQ 203


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-15 3 0|=
-14 19 0|==
-13 77 2|*=====
-12 230 86|======*===========
-11 400 449|=============================== *
-10 677 833|===================================================== *
-9 725 860|======================================================== *
-8 609 644|=============================================== *
-7 388 406|============================== *
-6 291 233|=================*=====
-5 159 128|=========*===
-4 95 68|=====*==
-3 39 36|==*
-2 27 19|=*=
-1 21 9|*=
0 4 5|*
1 2 2|*
2 2 1|*
3 2 0|=
4 3 0|=
5 1 0|=
> 6 16 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 343.6772
P(chi-square) = 0

Total sequences searched: 3790

Whole sequence top hits:
tophits_s report:
Total hits: 15
Satisfying E cutoff: 15
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 15
Satisfying E cutoff: 15
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: