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Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

1 accessions found for Acidithiobacillus ferrooxidans ATCC 23270  

Data for CP001219  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001219.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001219_1348 CDS_1237889-1239217 74.8 5.9e-21 1
CP001219_2809 CDS_2643001-2641481 71.3 5.6e-20 1
CP001219_2112 CDS_1985548-1982807 67.4 7.1e-19 1
CP001219_0178 CDS_162300-163892 61.6 3.1e-17 1
CP001219_2755 CDS_2579711-2578626 53.9 4.9e-15 1
CP001219_1920 CDS_1781196-1779889 47.8 2.6e-13 1
CP001219_3113 CDS_2952059-2953321 45.9 9e-13 1
CP001219_0022 CDS_24231-26363 44.5 2.2e-12 1
CP001219_0025 CDS_28118-29713 38.2 1.4e-10 1
CP001219_0430 CDS_390437-388953 35.0 1.1e-09 1
CP001219_2197 CDS_2065690-2064419 33.3 3.2e-09 1
CP001219_0102 CDS_99282-97942 33.3 3.3e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001219_1348 1/1 206 273 .. 1 87 [] 74.8 5.9e-21
CP001219_2809 1/1 250 318 .. 1 87 [] 71.3 5.6e-20
CP001219_2112 1/1 682 749 .. 1 87 [] 67.4 7.1e-19
CP001219_0178 1/1 306 371 .. 1 87 [] 61.6 3.1e-17
CP001219_2755 1/1 136 192 .. 1 78 [. 53.9 4.9e-15
CP001219_1920 1/1 218 283 .. 1 87 [] 47.8 2.6e-13
CP001219_3113 1/1 219 278 .. 1 87 [] 45.9 9e-13
CP001219_0022 1/1 483 554 .. 1 87 [] 44.5 2.2e-12
CP001219_0025 1/1 315 376 .. 1 83 [. 38.2 1.4e-10
CP001219_0430 1/1 265 333 .. 1 87 [] 35.0 1.1e-09
CP001219_2197 1/1 218 279 .. 1 87 [] 33.3 3.2e-09
CP001219_0102 1/1 227 287 .. 1 87 [] 33.3 3.3e-09

Alignments of top-scoring domains:
CP001219_1348: domain 1 of 1, from 206 to 273: score 74.8, E = 5.9e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHELR PLt++rg++e +l+ ++ + ++++
CP001219_1 206 VRQDFVANVSHELRSPLTVVRGFLENMLD--------SPIAADDEV- 243

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+ +++++ r+++L++dlL l+r+ea
CP001219_1 244 ----------SSQLRLMEQQTLRMQSLVEDLLSLARMEAA 273

CP001219_2809: domain 1 of 1, from 250 to 318: score 71.3, E = 5.6e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak fl+ lsHEL+TPLtaIr aelL+e+l +el++eq
CP001219_2 250 AKLHFLRQLSHELKTPLTAIREGAELLQEDLG------HELGAEQ-- 288

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+++++++ + rl+rLi+dlL +s +e +
CP001219_2 289 ----------QEIVHIVRDNSLRLQRLIEDLLRFSLAEGP 318

CP001219_2112: domain 1 of 1, from 682 to 749: score 67.4, E = 7.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l ++sH+LRTPL++++g+a +L++++ + l++e+
CP001219_2 682 LQNALLGAVSHDLRTPLAGVLGTATTLQRNA-------QGLTAEE-- 719

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++le i+++++ +++ ++++L ++ +++g
CP001219_2 720 ----------HDLLENIREQTQKMEHTVDRILHMAALQSG 749

CP001219_0178: domain 1 of 1, from 306 to 371: score 61.6, E = 3.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++an++HE+R+PL++Ir + lL e ++
CP001219_0 306 ALGRLAANIAHEIRNPLSVIRHAGNLLAE---------RMDDPAS-- 341

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l++++re+ r++++++ +L+++r
CP001219_0 342 ----------QHLLDILERETVRINAIVESVLEMARPSPA 371

CP001219_2755: domain 1 of 1, from 136 to 192: score 53.9, E = 4.9e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e+l++l+HE+++PL ++rg+a+lL + el +++
CP001219_2 136 AAQEMLRGLAHEIKNPLGGLRGAAQLLDR----------ELQRPEL- 171

peLRledpeyreyletilreaerllrLindl<-*
++y+++il+e++rl +L+++l
CP001219_2 172 ----------KDYTRVILHEVDRLHHLVDRL 192

CP001219_1920: domain 1 of 1, from 218 to 283: score 47.8, E = 2.6e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a+++HELRTPLta+++ ++ L++ ++ +e
CP001219_1 218 QERRFIADAAHELRTPLTALSLQVQNLER---------ADSLSEC-- 253

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l +++ +er ++L+++lL l+r ++
CP001219_1 254 ----------QKRLLPLQSGLERSRHLLDQLLGLARQQTA 283

CP001219_3113: domain 1 of 1, from 219 to 278: score 45.9, E = 9e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ l ++sH+LRTPLt +r+ ae L +e
CP001219_3 219 EREMVLVGVSHDLRTPLTRMRLSAEFLPAE----------------- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ + i+ ++ +++ i ++Ld++r +++
CP001219_3 249 ----------EEARSEIIANIQEMDKVIHQFLDYARSGEQ 278

CP001219_0022: domain 1 of 1, from 483 to 554: score 44.5, E = 2.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a se ++ l+HE+++PLt I++ ae L++++ +++ e++
CP001219_0 483 AWSEVARRLAHEIKNPLTPIQLSAERLRRKY----LERLGDEGETL- 524

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ti+++++ l +++ + +++r +
CP001219_0 525 ----------DRATRTIIHQVDALKVMVDAFSEYARQPQL 554

CP001219_0025: domain 1 of 1, from 315 to 376: score 38.2, E = 1.4e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+e+ a ++HE+R+ L+++rg+a L + e++
CP001219_0 315 TIGEMSAQVAHEIRNALSSLRGAARYLVR---------YEQPVNR-- 350

peLRledpeyreyletilreaerllrLindlLdlsr<-*
+e++++i++e++rl ++ + +Ld+ r
CP001219_0 351 ----------QEFINIIEEEVQRLYDMTQGFLDFGR 376

CP001219_0430: domain 1 of 1, from 265 to 333: score 35.0, E = 1.1e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ efl+ +sHEL TPL++ r +elLl + ++l + q
CP001219_0 265 LRHEFLSQVSHELITPLASARSGSELLLS------ERIGPLLPRQ-- 303

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re le+i r+++ l + i+++Ld+ ++a
CP001219_0 304 ----------REVLEIIVRQVKELYAAIQEMLDMHALQAR 333

CP001219_2197: domain 1 of 1, from 218 to 279: score 33.3, E = 3.2e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s +l ++sH+LR PL+ +r++ elL +
CP001219_2 218 HQSLLLTGISHDLRSPLARLRMAWELLPD-------------NTP-- 249

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + e +l+++er+++L+ + L l r +
CP001219_2 250 ----------QHLREGMLQDIERMDALLAQSLALGRGMSA 279

CP001219_0102: domain 1 of 1, from 227 to 287: score 33.3, E = 3.3e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +l ++sHELRTPL+ ++++++l ++ ++l + +
CP001219_0 227 ERTLLLTGISHELRTPLSRLLLTLHL-QD---------PDLLAGK-- 261

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l ++ +++ i+ +L+l r + +
CP001219_0 262 --------------AAMLVDVSEMDETIDKFLTLVRSGDE 287


Histogram of all scores:
score obs exp (one = represents 10 sequences)
----- --- ---
-15 3 0|=
-14 29 0|===
-13 82 2|*========
-12 232 71|=======*================
-11 367 373|=====================================*
-10 515 692|==================================================== *
-9 576 714|==========================================================*
-8 491 535|================================================== *
-7 304 337|=============================== *
-6 222 194|===================*===
-5 153 106|==========*=====
-4 71 56|=====*==
-3 31 30|==*=
-2 21 15|=*=
-1 15 8|*=
0 10 4|*
1 6 2|*
2 2 1|*
3 2 0|=
4 1 0|=
> 5 14 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 470.5154
P(chi-square) = 0

Total sequences searched: 3147

Whole sequence top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: