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Thermotogae
Classification of phyla is from NCBI page
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132 projects found  

1 accessions found for Methylocella silvestris BL2  

Data for CP001280  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001280.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001280_1845 CDS_2046615-2048993 98.0 1.8e-27 1
CP001280_1633 CDS_1808697-1807213 89.3 5.4e-25 1
CP001280_0188 CDS_201577-199190 88.8 7.6e-25 1
CP001280_2417 CDS_2701193-2706571 84.4 1.3e-23 1
CP001280_0825 CDS_925899-924808 82.7 4e-23 1
CP001280_3378 CDS_3814647-3817157 81.4 9.6e-23 1
CP001280_2756 CDS_3100740-3098035 80.7 1.5e-22 1
CP001280_1315 CDS_1437861-1439417 78.4 6.7e-22 1
CP001280_0249 CDS_293571-291736 74.2 1.1e-20 1
CP001280_0654 CDS_724826-722247 65.8 2.4e-18 1
CP001280_0515 CDS_586584-587729 58.8 2.4e-16 1
CP001280_1958 CDS_2171843-2175208 58.2 3.6e-16 1
CP001280_2285 CDS_2542452-2543915 53.7 6.6e-15 1
CP001280_2418 CDS_2706581-2708260 52.6 1.4e-14 1
CP001280_0186 CDS_194805-196268 51.6 2.6e-14 1
CP001280_0517 CDS_589478-591745 49.7 8.8e-14 1
CP001280_2620 CDS_2933845-2931845 48.7 1.7e-13 1
CP001280_1786 CDS_1991766-1989874 42.7 8.8e-12 1
CP001280_1490 CDS_1648233-1646815 41.7 1.7e-11 1
CP001280_3431 CDS_3875846-3873327 39.5 7e-11 1
CP001280_3492 CDS_3951860-3949908 37.5 2.7e-10 1
CP001280_3130 CDS_3524170-3522302 32.5 6.9e-09 1
CP001280_2714 CDS_3056985-3058661 31.3 1.5e-08 1
CP001280_3800 CDS_4281075-4283564 30.8 2.1e-08 1
CP001280_3329 CDS_3753090-3754460 30.4 2.6e-08 1
CP001280_2452 CDS_2746071-2747432 28.9 7e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001280_1845 1/1 560 628 .. 1 87 [] 98.0 1.8e-27
CP001280_1633 1/1 229 298 .. 1 87 [] 89.3 5.4e-25
CP001280_0188 1/1 537 606 .. 1 87 [] 88.8 7.6e-25
CP001280_2417 1/1 1125 1193 .. 1 87 [] 84.4 1.3e-23
CP001280_0825 1/1 127 194 .. 1 87 [] 82.7 4e-23
CP001280_3378 1/1 596 665 .. 1 87 [] 81.4 9.6e-23
CP001280_2756 1/1 669 737 .. 1 87 [] 80.7 1.5e-22
CP001280_1315 1/1 261 330 .. 1 87 [] 78.4 6.7e-22
CP001280_0249 1/1 362 427 .. 1 87 [] 74.2 1.1e-20
CP001280_0654 1/1 619 687 .. 1 87 [] 65.8 2.4e-18
CP001280_0515 1/1 145 209 .. 1 87 [] 58.8 2.4e-16
CP001280_1958 1/1 674 738 .. 1 87 [] 58.2 3.6e-16
CP001280_2285 1/1 113 183 .. 1 87 [] 53.7 6.6e-15
CP001280_2418 1/1 192 258 .. 1 87 [] 52.6 1.4e-14
CP001280_0186 1/1 236 302 .. 1 87 [] 51.6 2.6e-14
CP001280_0517 1/1 508 579 .. 1 87 [] 49.7 8.8e-14
CP001280_2620 1/1 440 510 .. 1 87 [] 48.7 1.7e-13
CP001280_1786 1/1 400 472 .. 1 87 [] 42.7 8.8e-12
CP001280_1490 1/1 237 303 .. 1 87 [] 41.7 1.7e-11
CP001280_3431 1/1 464 530 .. 1 87 [] 39.5 7e-11
CP001280_3492 1/1 280 346 .. 1 87 [] 37.5 2.7e-10
CP001280_3130 1/1 247 314 .. 1 87 [] 32.5 6.9e-09
CP001280_2714 1/1 188 256 .. 1 87 [] 31.3 1.5e-08
CP001280_3800 1/1 454 520 .. 1 87 [] 30.8 2.1e-08
CP001280_3329 1/1 235 300 .. 1 87 [] 30.4 2.6e-08
CP001280_2452 1/1 250 308 .. 1 87 [] 28.9 7e-08

Alignments of top-scoring domains:
CP001280_1845: domain 1 of 1, from 560 to 628: score 98.0, E = 1.8e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks+f+an+sHELRTPL+aI+gyaelL+++l+ +el++
CP001280_1 560 HKSRFFANMSHELRTPLNAILGYAELLRDGLY------GELPDRA-- 598

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ le++++ + +ll Lind+Ldls++eag
CP001280_1 599 ----------KSVLERVESNGAHLLGLINDVLDLSKLEAG 628

CP001280_1633: domain 1 of 1, from 229 to 298: score 89.3, E = 5.4e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+ flan+sHELRTPL+aI+g++e+L + + + + +++q
CP001280_1 229 SKDHFLANVSHELRTPLNAIIGFSEILGD-----ADQAPRDPAKQ-- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey +i+r++++ll+ +n +Ldls+i +g
CP001280_1 269 ----------REYAAIIHRSGQHLLSVVNSILDLSKIHSG 298

CP001280_0188: domain 1 of 1, from 537 to 606: score 88.8, E = 7.6e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
akseflan+sHELRTPL+aI+g++e+++ e + ++l++++
CP001280_0 537 AKSEFLANMSHELRTPLNAIIGFSEVMQQETF------GPLGSKK-- 575

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y +y + i++++e+ll i+d+Ld+sr+e+g
CP001280_0 576 ---------YVDYSNDIKQSGEYLLGVISDVLDMSRLESG 606

CP001280_2417: domain 1 of 1, from 1125 to 1193: score 84.4, E = 1.3e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++I+ + + L ++++ ++ls+ q
CP001280_2 1125 YKSEFLANMSHELRTPLNSILILGQQLSDNVE------HNLSDRQ-- 1163

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e +ti+ ++ ll+Li+d+Ldls+ie+g
CP001280_2 1164 ----------VECARTIHAAGSDLLNLISDILDLSKIESG 1193

CP001280_0825: domain 1 of 1, from 127 to 194: score 82.7, E = 4e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +f+an+sHELRTPL++++g++e+L+ +++++ ++
CP001280_0 127 MRVDFVANASHELRTPLASLLGFVETLQG---------PARDDSAAR 164

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l+++ ++a+r+ rL++dlL lsrie+
CP001280_0 165 ----------GKFLKIMGEQARRMTRLVDDLLSLSRIEQH 194

CP001280_3378: domain 1 of 1, from 596 to 665: score 81.4, E = 9.6e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks+fla +sHE+RTPL+aI+g+ae++ e + ++ +
CP001280_3 596 LKSDFLAKVSHEIRTPLNAIIGFAEVIME------ERFGPIGNAR-- 634

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++yl+ i++++ +L+ndlLdls+ieag
CP001280_3 635 ---------YKDYLKDIHSSGSLVMSLVNDLLDLSKIEAG 665

CP001280_2756: domain 1 of 1, from 669 to 737: score 80.7, E = 1.5e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s +l ++sH+LRTPL++I+g+a +L +++ + l++e +
CP001280_2 669 LRSALLTSISHDLRTPLASIMGAAGALSDFA-------GQLTDESK- 707

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re+++ti++eaerl+r i +lLd++r+e+g
CP001280_2 708 ----------RELTDTIQEEAERLNRFIANLLDMTRLESG 737

CP001280_1315: domain 1 of 1, from 261 to 330: score 78.4, E = 6.7e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHELRTPL+aI+g++e+++ el+ ++
CP001280_1 261 AKSHFLATMSHELRTPLNAILGFSEVMKGELF------GAHIVAS-- 299

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ey + i+ ++++ll Lin++Ldlsrieag
CP001280_1 300 ---------YKEYSNDIHASGHHLLMLINEILDLSRIEAG 330

CP001280_0249: domain 1 of 1, from 362 to 427: score 74.2, E = 1.1e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+a+++HEL++PLt++r ++e+L + +++e q
CP001280_0 362 AIESFAADVAHELKNPLTSLRSAVETLPN---------VKKPESQ-- 397

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +i+++++rl+rLi+d+ d sr++a+
CP001280_0 398 ----------ARLLAVIQHDVKRLDRLISDISDASRLDAE 427

CP001280_0654: domain 1 of 1, from 619 to 687: score 65.8, E = 2.4e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ ++s ELR PLt I+g+++lL + ++ ++l++ q
CP001280_0 619 LRNDFVHHVSYELRSPLTNIIGFIQLLGD------PSVGPLNPRQ-- 657

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey + +++ ll++ind+Ldl+ i+a
CP001280_0 658 ----------LEYAGYVTKSSSALLAIINDILDLASIDAD 687

CP001280_0515: domain 1 of 1, from 145 to 209: score 58.8, E = 2.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++++l+HE+++PL++Irg+a+lL++ e+++ +
CP001280_0 145 SVAAMASMLAHEIKNPLSGIRGAAQLLET----------EANDSD-- 179

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +++ i +e++r+ +L++++ +s +
CP001280_0 180 ----------RALTRLICEETDRIVKLVDRMSAFSDGRPI 209

CP001280_1958: domain 1 of 1, from 674 to 738: score 58.2, E = 3.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+ + +lsHE+RTPL++I gya+l++ ++ e +
CP001280_1 674 AKSRYIVGLSHEIRTPLNSIFGYAQLMEG-----------APIESN- 708

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +++i+r ae+l +L++ lLd+srie+g
CP001280_1 709 ----------ADGVRIIRRNAEHLASLLDGLLDISRIETG 738

CP001280_2285: domain 1 of 1, from 113 to 183: score 53.7, E = 6.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++fla++sH+L +PL++ r+++ +L e + +e s++q +
CP001280_2 113 SKTRFLAAASHDLHQPLNVARLFLGMLGE-------HVGEYSDPQSR 152

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e++ i+ +++ ++L++ l d+sr++ag
CP001280_2 153 G---------SELVANIEAALDTVDELVRTLVDISRLDAG 183

CP001280_2418: domain 1 of 1, from 192 to 258: score 52.6, E = 1.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ LtaI+g +elL++ l++e r
CP001280_2 192 AIGQLTGGVAHDFNNLLTAIMGSLELLKK----------RLPDEPR- 227

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++++t+ + aer +L ++lL +sr ++
CP001280_2 228 ---------ISRLVDTAMQGAERGAALTQRLLAFSRRQEL 258

CP001280_0186: domain 1 of 1, from 236 to 302: score 51.6, E = 2.6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + n++H+L+TPLt +r+ ae++l ++ +++e+
CP001280_0 236 GLKQVSDNIAHDLKTPLTRLRARAEAALQFG---------KTPED-- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr +le++l+e++rl ++ + lL ++r+eag
CP001280_0 272 ---------YRGALEKVLEESDRLIQIFDALLKIARAEAG 302

CP001280_0517: domain 1 of 1, from 508 to 579: score 49.7, E = 8.8e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++ ++HE+R+PLt I++ ae L++++ g+ + ++
CP001280_0 508 AWADVARRIAHEIRNPLTPIQLSAERLKRKY-----GRLITQDRDI- 548

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ti+r+++ + r+++++ ++r+ +
CP001280_0 549 ---------FDQCTDTIIRQVDDIKRMVDEFSSFARMPKP 579

CP001280_2620: domain 1 of 1, from 440 to 510: score 48.7, E = 1.7e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+a+++HE ++PL+aI +ya+ +++l e+++ q
CP001280_2 440 LLGQFAASIAHEVNQPLAAITTYAQSGRRWLT------REAPAAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+r+ l+ i + ++r ++ + l l++ +a
CP001280_2 479 --------EVRDCLDHIVENGRRASEVVAGLKALTKKGAA 510

CP001280_1786: domain 1 of 1, from 400 to 472: score 42.7, E = 8.8e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++e++++l+HEL++PLtaI y+ +++ ld ++++ ++
CP001280_1 400 AMGEMASTLAHELNQPLTAIASYLNGCRRLLD------ADRGGDK-- 438

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++r+ +e++ +a r ++i +++++ ++
CP001280_1 439 ------VAMVRDGVERAAAQALRAGQIIKRMRQFVARGES 472

CP001280_1490: domain 1 of 1, from 237 to 303: score 41.7, E = 1.7e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ n++H+LRTPL+ +rg +el+ + ls+e++
CP001280_1 237 GVRQVSDNIAHDLRTPLSRMRGRLELAAK---------RRLSAEHA- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + e++r l+L + +L ++r+e++
CP001280_1 274 ----------DILIRETIGELDRVLALFSAILRIARLETQ 303

CP001280_3431: domain 1 of 1, from 464 to 530: score 39.5, E = 7e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ LtaI+g+++lLl++ + +++
CP001280_3 464 AIGQLAGGVAHDFNNVLTAIIGFSDLLLAN--------HRPTDPS-- 500

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i++ a r L+++lL +sr ++
CP001280_3 501 ----------FRDIMQIKQNAIRAAGLVRQLLAFSRRQTL 530

CP001280_3492: domain 1 of 1, from 280 to 346: score 37.5, E = 2.7e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ L aI+g +el ++ + +++++
CP001280_3 280 AIGQLTGGVAHDFNNLLMAILGSLELVQK--------RLPADPKI-- 316

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ ++ +a+r +L +++L ++r ++
CP001280_3 317 ----------ASLIDNAILAAQRGTSLTQRMLAFARRQEL 346

CP001280_3130: domain 1 of 1, from 247 to 314: score 32.5, E = 6.9e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ L++++ + lL++++ e+++ +
CP001280_3 247 AIGQLTGGIAHDFNNMLAVVISSLNLLKRRV--------ERGDTD-- 283

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++++ +l+ a+r L +lL ++r +
CP001280_3 284 ---------FMKFVDGALDGAQRAATLTHRLLAFARQQPL 314

CP001280_2714: domain 1 of 1, from 188 to 256: score 31.3, E = 1.5e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ Lt+++g ++++++ + +++ e+
CP001280_2 188 AVGQLTGGIAHDFNNMLTGVIGSLDIMRR------RIASHRLEDL-- 226

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + + +a+r L ++lL +sr ++
CP001280_2 227 ----------DRFMDAAAASANRAAGLTQRLLAFSRRQSL 256

CP001280_3800: domain 1 of 1, from 454 to 520: score 30.8, E = 2.1e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++++++H +++ + aI+gyae++++++ ++++ +
CP001280_3 454 TVGALTSGIAHNFNNIIGAILGYAEMAEAKV--------KADARLI- 491

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l+ i+r+ae ++Li+++L + r +
CP001280_3 492 -----------RDLHEIRRAAELARDLIDQILVFGRPRDA 520

CP001280_3329: domain 1 of 1, from 235 to 300: score 30.4, E = 2.6e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + n++H+LR PL+ r+ +e l+ ++ e+++
CP001280_3 235 QIRSVSDNIAHDLRSPLAITRLSLERGLA----------AAAEKDL- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r ++e++l e++r l ++ lL +s ie g
CP001280_3 271 ----------RLATERALAELDRALTTVSALLRISEIELG 300

CP001280_2452: domain 1 of 1, from 250 to 308: score 28.9, E = 7e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +l ++sH+LRT Lt ++ + l+ + +e+
CP001280_2 250 QRTTMLNGVSHDLRTVLTRFKLSLALMPD-------------SEE-- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +++++ ++r+++ L ++r ag
CP001280_2 282 -------------TQELQKDVAEMQRMLEAYLAFARGAAG 308


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-15 1 0|=
-14 12 0|=
-13 38 2|*==
-12 155 87|======*=====
-11 350 452|=========================== *
-10 650 839|================================================== *
-9 731 867|========================================================= *
-8 674 649|=================================================*==
-7 465 409|===============================*====
-6 292 235|==================*====
-5 200 129|=========*======
-4 113 69|=====*===
-3 54 36|==*==
-2 26 19|=*
-1 13 10|*
0 8 5|*
1 3 2|*
2 3 1|*
3 1 0|=
> 4 29 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 242.0538
P(chi-square) = 1.061e-314

Total sequences searched: 3818

Whole sequence top hits:
tophits_s report:
Total hits: 26
Satisfying E cutoff: 26
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 26
Satisfying E cutoff: 26
Total memory: 31K


Acknowledgements:

This research is funded by:

Developed by: