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Thermotogae
Classification of phyla is from NCBI page
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1 accessions found for Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  

Data for CP001358  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001358.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001358_0189 CDS_241110-243110 98.9 6.4e-28 1
CP001358_1581 CDS_1925975-1928032 85.9 3.1e-24 1
CP001358_0558 CDS_687006-689015 78.8 3.2e-22 1
CP001358_0839 CDS_996825-998411 73.6 9.6e-21 1
CP001358_2152 CDS_2625559-2622536 68.4 2.8e-19 1
CP001358_0083 CDS_107283-109907 60.8 4.1e-17 1
CP001358_1659 CDS_2020588-2023473 53.2 5.8e-15 1
CP001358_0756 CDS_899903-901924 53.1 6.1e-15 1
CP001358_0719 CDS_856208-857899 49.5 6.5e-14 1
CP001358_0184 CDS_234547-236112 44.7 1.4e-12 1
CP001358_0805 CDS_955901-957256 30.8 1.3e-08 1
CP001358_0801 CDS_952510-954273 29.3 3.3e-08 1
CP001358_1548 CDS_1885547-1883844 28.7 4.9e-08 1
CP001358_2246 CDS_2735327-2733888 28.0 7.8e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001358_0189 1/1 284 349 .. 1 87 [] 98.9 6.4e-28
CP001358_1581 1/1 310 375 .. 1 87 [] 85.9 3.1e-24
CP001358_0558 1/1 445 510 .. 1 87 [] 78.8 3.2e-22
CP001358_0839 1/1 309 375 .. 1 87 [] 73.6 9.6e-21
CP001358_2152 1/1 319 384 .. 1 87 [] 68.4 2.8e-19
CP001358_0083 1/1 249 315 .. 1 87 [] 60.8 4.1e-17
CP001358_1659 1/1 717 784 .. 1 87 [] 53.2 5.8e-15
CP001358_0756 1/1 449 515 .. 1 87 [] 53.1 6.1e-15
CP001358_0719 1/1 273 346 .. 1 87 [] 49.5 6.5e-14
CP001358_0184 1/1 287 353 .. 1 87 [] 44.7 1.4e-12
CP001358_0805 1/1 136 210 .. 1 87 [] 30.8 1.3e-08
CP001358_0801 1/1 344 419 .. 1 87 [] 29.3 3.3e-08
CP001358_1548 1/1 332 406 .. 1 87 [] 28.7 4.9e-08
CP001358_2246 1/1 263 310 .. 1 76 [. 28.0 7.8e-08

Alignments of top-scoring domains:
CP001358_0189: domain 1 of 1, from 284 to 349: score 98.9, E = 6.4e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks flan+sHE+RTP+++I+g+a+l l+ t+ls++q
CP001358_0 284 AKSIFLANMSHEIRTPMNGIMGMAHLVLN---------TDLSPQQ-- 319

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y+e+i++ e+ll++indlLd+s+iea+
CP001358_0 320 ----------RDYVEKIHSTCESLLDIINDLLDFSKIEAN 349

CP001358_1581: domain 1 of 1, from 310 to 375: score 85.9, E = 3.1e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+efla++sHE+RTPL++I+g+++l+l ++ ++
CP001358_1 310 AKTEFLAHMSHEIRTPLNGIIGLTHLALQ----------SGPDGEL- 345

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl +i++++ ll++ind+Ldls+iea+
CP001358_1 346 ----------KEYLLKIRSSSTNLLAIINDVLDLSKIEAN 375

CP001358_0558: domain 1 of 1, from 445 to 510: score 78.8, E = 3.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHELRTPLtaI+gyae+L + ++e
CP001358_0 445 VRRDFVANVSHELRTPLTAIQGYAETLTS---------LDGPPEC-- 480

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ e+il+ + l+r+++dlL+l+r+e
CP001358_0 481 ----------RRFGEIILKNGACLSRMVDDLLTLARLEGK 510

CP001358_0839: domain 1 of 1, from 309 to 375: score 73.6, E = 9.6e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++ +a+++HE+R+PL Ir aelL++ ++++++ +
CP001358_0 309 SMGRVIASIAHEIRNPLGIIRSSAELLQR--------RSDADAGT-- 345

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++l i +e+ rl++ +nd+Ld++r +++
CP001358_0 346 ----------RRILGAIFDESVRLSQTVNDFLDYARPRQP 375

CP001358_2152: domain 1 of 1, from 319 to 384: score 68.4, E = 2.8e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++fl+ +sHE+RTPL+aI+g++ l l t+l+ q
CP001358_2 319 VQDDFLRRISHEIRTPLNAIIGMSYLSLQ---------TDLNGVQ-- 354

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+yl i +++ ll+++n++Ld+s + +g
CP001358_2 355 ----------RDYLAQINKSGSVLLDMVNRILDFSSASEG 384

CP001358_0083: domain 1 of 1, from 249 to 315: score 60.8, E = 4.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks f+a lsH++RTPLtaI+g++elL+ ++ se +r
CP001358_0 249 MKSAFMARLSHDMRTPLTAILGMSELLQQ---------QNVSERDR- 285

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ + +++ ll++++d+ d + +e+g
CP001358_0 286 ----------KKALRYLTQAGSALLEMVRDITDHATLEQG 315

CP001358_1659: domain 1 of 1, from 717 to 784: score 53.2, E = 5.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + l+++sH+LRTPLtaI g+a +L ++ ++ + r
CP001358_1 717 LRADVLRSVSHDLRTPLTAICGNAAMLAAG--------GDIEMQRR- 754

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + i+++a++l +++++lL l+r+e+
CP001358_1 755 ----------KSLARAIEEDARYLVEMVENLLALTRLEQY 784

CP001358_0756: domain 1 of 1, from 449 to 515: score 53.1, E = 6.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE R+PL++I+g a + + l+
CP001358_0 449 ALGHLAAGVAHEVRNPLSTIKGVALYIAK---------RMLPGGRE- 485

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ +++++e++rl+r +++lL+++r +a
CP001358_0 486 ----------EEAAQRMIDEVDRLDRVVSELLEFARPGAI 515

CP001358_0719: domain 1 of 1, from 273 to 346: score 49.5, E = 6.5e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkv.lagdtelseeqr
+ s f+ ++sHELRTPLt+++g +e+L+++l ++l + t++ e
CP001358_0 273 RESHFTGDVSHELRTPLTVMQGGLEVLEARL--QnLVRATPQAGEL- 316

lpeLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++lr + + r ++ lL l+r +
CP001358_0 317 -----------VPVVGRLLRTTSDMTRTVRTLLLLARKPGE 346

CP001358_0184: domain 1 of 1, from 287 to 353: score 44.7, E = 1.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++a+++HE+R+PL++I+gya ++ + ++e+
CP001358_0 287 AVGNLAAGVAHEIRNPLSSIKGYATYFGQRF--------PEGSED-- 323

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + +++ +e++rl+r i dl lsr
CP001358_0 324 ----------RAAANVMVSEVDRLNRVIMDLIGLSRPSDV 353

CP001358_0805: domain 1 of 1, from 136 to 210: score 30.8, E = 1.3e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++ + +++HE ++PL+ ++ +a l+++ l+e++++
CP001358_0 136 SLGRVAEGVAHEVNNPLNIMMQAAGLIRD----------CLDEPEAQ 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + e re+++ti+ ++ r +++ + lL
CP001358_0 173 ALA--DVDEMREAVNTIRAQSLRVREITRKLLMVGHGLDA 210

CP001358_0801: domain 1 of 1, from 344 to 419: score 29.3, E = 3.3e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++++a+++HE ++PL++I a l+++ ls ++
CP001358_0 344 SIGRLAAGVAHEVNNPLAVIYEKAGLARD----------LLSMGKVC 380

peLR....ledpeyreyletilreaerllrLindlLdlsrieag<-*
+e R++++l +le i++ +er +++ +lL ++r +
CP001358_0 381 GESRdrerL-----NGLLEGIESTVERARSITHRLLGFARRMEA 419

CP001358_1548: domain 1 of 1, from 332 to 406: score 28.7, E = 4.9e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++a+++HE ++PL I+ +a +++ ld +e++e +
CP001358_1 332 ALGKMAAGVAHEVNNPLMLIQENAGWIRDLLD------DEKPEAMK- 371

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ e +e+i++ ++r + +++L + r ++
CP001358_1 372 -----NYQEILESTEKIDQHVKRAKGITQRMLGFGRRMNP 406

CP001358_2246: domain 1 of 1, from 263 to 310: score 28.0, E = 7.8e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++ +a+lsH+LRTPLt +r+ +e
CP001358_2 263 ERERVFAALSHDLRTPLTRMRLRLESTPP------------------ 291

peLRledpeyreyletilreaerllrLin<-*
+ +++l+++++l + ++
CP001358_2 292 ----------GTFRQKMLEDVQSLHSTVE 310


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-14 14 0|==
-13 33 1|*====
-12 104 53|======*======
-11 214 279|=========================== *
-10 395 518|================================================== *
-9 465 535|==========================================================*
-8 412 400|=================================================*==
-7 268 252|===============================*==
-6 172 145|==================*===
-5 138 79|=========*========
-4 57 42|=====*==
-3 33 22|==*==
-2 10 11|=*
-1 10 6|*=
0 6 3|*
1 3 1|*
2 5 0|=
3 2 0|=
> 4 15 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 161.5467
P(chi-square) = 6.442e-29

Total sequences searched: 2356

Whole sequence top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: